|
US20120101114A1
(en)
|
2007-03-28 |
2012-04-26 |
Pharmacyclics, Inc. |
Inhibitors of bruton's tyrosine kinase
|
|
WO2011152351A1
(ja)
|
2010-05-31 |
2011-12-08 |
小野薬品工業株式会社 |
プリノン誘導体
|
|
MX342405B
(es)
|
2010-06-03 |
2016-09-28 |
Pharmacyclics Inc |
El uso de inhibidores de la tirosina quinasa de bruton (btk).
|
|
WO2012158795A1
(en)
|
2011-05-17 |
2012-11-22 |
Principia Biopharma Inc. |
Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors
|
|
PT2710005T
(pt)
|
2011-05-17 |
2016-11-16 |
Principia Biopharma Inc |
Inibidores de tirosina-quinase
|
|
EA201490265A1
(ru)
|
2011-07-13 |
2014-12-30 |
Фармасайкликс, Инк. |
Ингибиторы тирозинкиназы брутона
|
|
ES2950569T3
(es)
|
2011-07-19 |
2023-10-11 |
Merck Sharp & Dohme |
(S)-4-(8-amino-3-(1-(but-2-inoil)pirrolidin-2-il)imidazo[1,5-a]pirazin-1-il)-2-metoxi-n-(piridin-2-il)benzamida como inhibidor de la Btk
|
|
EP2548877A1
(en)
|
2011-07-19 |
2013-01-23 |
MSD Oss B.V. |
4-(5-Membered fused pyridinyl)benzamides as BTK-inhibitors
|
|
LT2786996T
(lt)
|
2011-11-29 |
2017-01-10 |
Ono Pharmaceutical Co., Ltd. |
Purinono darinio hidrochloridas
|
|
US8377946B1
(en)
|
2011-12-30 |
2013-02-19 |
Pharmacyclics, Inc. |
Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors
|
|
US8501724B1
(en)
*
|
2012-01-31 |
2013-08-06 |
Pharmacyclics, Inc. |
Purinone compounds as kinase inhibitors
|
|
MX387669B
(es)
|
2012-06-04 |
2025-03-18 |
Pharmacyclics Llc |
Formas cristalinas de un inhibidor de tirosina quinasa de bruton.
|
|
BR112015001690A2
(pt)
|
2012-07-24 |
2017-11-07 |
Pharmacyclics Inc |
mutações associadas com a resistência a inibidores da tirosina quinase de bruton (btk)
|
|
PE20150756A1
(es)
|
2012-08-10 |
2015-06-03 |
Boehringer Ingelheim Int |
Compuestos heteroaromaticos como inhibidores de btk
|
|
PT2892900T
(pt)
|
2012-09-10 |
2017-11-06 |
Principia Biopharma Inc |
Compostos de pirazolopirimidina como inibidores de cinase
|
|
BR112015011171A2
(pt)
|
2012-11-15 |
2017-07-11 |
Pharmacyclics Inc |
compostos de pirrolopirimidina como inibidores da quinase
|
|
US8895750B2
(en)
|
2013-03-14 |
2014-11-25 |
Boehringer Ingelheim International Gmbh |
Heteroaromatic compounds as BTK inhibitors
|
|
WO2014152114A1
(en)
|
2013-03-15 |
2014-09-25 |
Boehringer Ingelheim International Gmbh |
Heteroaromatic compounds as btk inhibitors
|
|
US8957080B2
(en)
|
2013-04-09 |
2015-02-17 |
Principia Biopharma Inc. |
Tyrosine kinase inhibitors
|
|
EA028756B1
(ru)
|
2013-04-25 |
2017-12-29 |
Бэйджин, Лтд. |
Конденсированные гетероциклические соединения в качестве ингибиторов протеинкиназы
|
|
US9637487B2
(en)
*
|
2013-07-02 |
2017-05-02 |
Pharmacyclics Llc |
Purinone compounds as kinase inhibitors
|
|
PL3702373T3
(pl)
|
2013-09-13 |
2022-12-05 |
Beigene Switzerland Gmbh |
Przeciwciała anty-PD1 i ich zastosowanie jako środki terapeutyczne i diagnostyczne
|
|
US9624224B2
(en)
|
2013-09-30 |
2017-04-18 |
Pharmacyclics Llc |
Inhibitors of Bruton's tyrosine kinase
|
|
CN113995843A
(zh)
*
|
2013-11-07 |
2022-02-01 |
豪夫迈·罗氏有限公司 |
抗cd20抗体与btk抑制剂的组合疗法
|
|
JP2016540053A
(ja)
|
2013-12-05 |
2016-12-22 |
アセルタ ファーマ ビー．ブイ． |
Ｐｉ３ｋ阻害剤とｂｔｋ阻害剤の治療的組み合わせ
|
|
US10272083B2
(en)
|
2014-01-21 |
2019-04-30 |
Acerta Pharma B.V. |
Methods of treating chronic lymphocytic leukemia and small lymphocytic leukemia using a BTK inhibitor
|
|
JP6486954B2
(ja)
|
2014-01-29 |
2019-03-20 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｂｔｋ阻害剤としてのピラゾール化合物
|
|
PT3107544T
(pt)
|
2014-02-21 |
2021-01-05 |
Principia Biopharma Inc |
Sais e forma sólida de um inibidor de btk
|
|
KR20160127754A
(ko)
|
2014-03-12 |
2016-11-04 |
노파르티스 아게 |
Btk 억제제 및 akt 억제제를 포함하는 조합물
|
|
US9885086B2
(en)
|
2014-03-20 |
2018-02-06 |
Pharmacyclics Llc |
Phospholipase C gamma 2 and resistance associated mutations
|
|
EP3122360B1
(en)
|
2014-03-25 |
2020-06-17 |
ONO Pharmaceutical Co., Ltd. |
Prophylactic agent and/or therapeutic agent for diffuse large b-cell lymphoma
|
|
WO2015181633A2
(en)
*
|
2014-04-11 |
2015-12-03 |
Acerta Pharma B.V. |
Methods of blocking the cxcr-4/sdf-1 signaling pathway with inhibitors of bruton's tyrosine kinase
|
|
TW202134236A
(zh)
|
2014-06-12 |
2021-09-16 |
美商西爾拉癌症醫學公司 |
N-(氰基甲基)-4-(2-(4-𠰌啉基苯基胺基)嘧啶-4-基)苯甲醯胺
|
|
KR20170012558A
(ko)
|
2014-06-13 |
2017-02-02 |
길리애드 사이언시즈, 인코포레이티드 |
포스파티딜이노시톨 3-키나제 억제제
|
|
AU2015274696B2
(en)
|
2014-06-13 |
2018-09-27 |
Gilead Sciences, Inc. |
Phosphatidylinositol 3-kinase inhibitors
|
|
TW201613644A
(en)
|
2014-06-17 |
2016-04-16 |
Acerta Pharma Bv |
Therapeutic combinations of a BTK inhibitor, a PI3K inhibitor, and/or a JAK-2 inhibitor
|
|
CN110156892B
(zh)
|
2014-07-03 |
2023-05-16 |
百济神州有限公司 |
抗pd-l1抗体及其作为治疗剂及诊断剂的用途
|
|
WO2016019233A1
(en)
|
2014-08-01 |
2016-02-04 |
Pharmacyclics Llc |
Inhibitors of bruton's tyrosine kinase
|
|
CA2955747A1
(en)
|
2014-08-07 |
2016-02-11 |
Pharmacyclics Llc |
Novel formulations of a bruton's tyrosine kinase inhibitor
|
|
HRP20211813T1
(hr)
|
2014-08-11 |
2022-03-04 |
Acerta Pharma B.V. |
Terapeutske kombinacije inhibitora btk i inhibitora bcl-2
|
|
CA2970723C
(en)
|
2014-12-18 |
2023-09-05 |
Principia Biopharma Inc. |
Treatment of pemphigus
|
|
IL315294A
(en)
|
2015-03-03 |
2024-10-01 |
Pharmacyclics Llc |
Pharmaceutical formulations of bruton's tyrosine kinase inhibitor
|
|
MY199989A
(en)
|
2015-03-04 |
2023-12-02 |
Gilead Sciences Inc |
Toll-like receptor modulating 4,6-diamino-pyrido[3,2-d]pyrimidine compounds
|
|
US10239879B2
(en)
|
2015-04-09 |
2019-03-26 |
Ono Pharmaceutical Co., Ltd. |
Process for producing purinone derivative
|
|
PE20180521A1
(es)
|
2015-06-03 |
2018-03-14 |
Principia Biopharma Inc |
Inhibidores de tirosina-cinasas
|
|
JP6785804B2
(ja)
*
|
2015-06-23 |
2020-11-18 |
ギリアド サイエンシズ， インコーポレイテッド |
Ｂ細胞悪性腫瘍を治療するための組合せ療法
|
|
EP3313839A1
(en)
|
2015-06-24 |
2018-05-02 |
Principia Biopharma Inc. |
Tyrosine kinase inhibitors
|
|
RS60411B1
(sr)
|
2015-07-02 |
2020-07-31 |
Acerta Pharma Bv |
Čvrsti oblici i formulacije (s)-4-(8-amino-3-(1-(but-2-inoil)pirolidin-2-il)imidazo[1,5-a]pirazin-1-il)-n-(piridin-2-il)benzamida
|
|
WO2017035230A1
(en)
|
2015-08-26 |
2017-03-02 |
Gilead Sciences, Inc. |
Deuterated toll-like receptor modulators
|
|
CN105753863B
(zh)
*
|
2015-09-11 |
2018-07-31 |
东莞市真兴贝特医药技术有限公司 |
氧代二氢咪唑并吡啶类化合物及其应用
|
|
US20190054090A1
(en)
|
2015-10-01 |
2019-02-21 |
Gilead Sciences, Inc. |
Combination of a btk inhibitor and a checkpoint inhibitor for treating cancers
|
|
EP3414234B1
(en)
|
2015-10-14 |
2022-06-29 |
Zibo Biopolar Changsheng Pharmaceutical Co. Ltd. |
Bruton's tyrosine kinase inhibitors
|
|
EA034561B1
(ru)
|
2015-12-16 |
2020-02-20 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Бипиразолильные производные, пригодные для лечения аутоиммунных заболеваний
|
|
US10570118B2
(en)
|
2016-01-13 |
2020-02-25 |
Boehringer Ingelheim International Gmbh |
Isoquinolones as BTK inhibitors
|
|
CA3016081A1
(en)
|
2016-03-04 |
2017-09-08 |
Gilead Sciences, Inc. |
Compositions and combinations of autotaxin inhibitors
|
|
US20170306050A1
(en)
|
2016-04-08 |
2017-10-26 |
Gilead Sciences, Inc. |
Compositions and methods for treating cancer, inflammatory diseases and autoimmune diseases
|
|
EP4019019B1
(en)
|
2016-05-20 |
2024-02-07 |
Biohaven Pharmaceutical Holding Company Ltd. |
Use of riluzole, riluzole prodrugs or riluzole analogs with immunotherapies to treat cancers
|
|
BR102017010009A2
(pt)
|
2016-05-27 |
2017-12-12 |
Gilead Sciences, Inc. |
Compounds for the treatment of hepatitis b virus infection
|
|
KR102202984B1
(ko)
|
2016-05-27 |
2021-01-13 |
길리애드 사이언시즈, 인코포레이티드 |
Ns5a, ns5b 또는 ns3 억제제를 사용하여 b형 간염 바이러스 감염을 치료하는 방법
|
|
IL293621B2
(en)
|
2016-06-29 |
2023-09-01 |
Principia Biopharma Inc |
Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[4,3-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4 -Methyl-4-[4-(oxane-3-yl)piperazine-1-yl)penta-2-ananitrile
|
|
WO2018002958A1
(en)
*
|
2016-06-30 |
2018-01-04 |
Sun Pharma Advanced Research Company Limited |
Novel hydrazide containing compounds as btk inhibitors
|
|
WO2018007885A1
(en)
|
2016-07-05 |
2018-01-11 |
Beigene, Ltd. |
COMBINATION OF A PD-l ANTAGONIST AND A RAF INHIBITOR FOR TREATING CANCER
|
|
MX384627B
(es)
|
2016-08-16 |
2025-03-14 |
Beigene Ltd |
Forma cristalina de (s)-7-(1-acriloilpiperidin-4-il)-2-(4-fenoxifenil)-4,5,6,7-tetra-hidropirazolo[1,5-a]pirimidin-3-carboxamida, preparacion y usos de la misma
|
|
WO2018033091A1
(zh)
*
|
2016-08-17 |
2018-02-22 |
深圳市塔吉瑞生物医药有限公司 |
用于抑制酪氨酸激酶活性的稠合双环类化合物
|
|
CN107759602B
(zh)
*
|
2016-08-17 |
2020-04-21 |
中国科学院上海药物研究所 |
含有共轭联烯结构的化合物、其药物组合物和用途
|
|
AU2017313085B2
(en)
|
2016-08-19 |
2024-06-20 |
Beone Medicines I Gmbh |
Use of a combination comprising a Btk inhibitor for treating cancers
|
|
JOP20190024A1
(ar)
|
2016-08-26 |
2019-02-19 |
Gilead Sciences Inc |
مركبات بيروليزين بها استبدال واستخداماتها
|
|
AU2017318601B2
(en)
|
2016-09-02 |
2020-09-03 |
Gilead Sciences, Inc. |
Toll like receptor modulator compounds
|
|
ES2826748T3
(es)
|
2016-09-02 |
2021-05-19 |
Gilead Sciences Inc |
Derivados de 4,6-diamino-pirido[3,2-d]pirimidina como moduladores de receptores de tipo Toll
|
|
IL295972A
(en)
*
|
2016-09-16 |
2022-10-01 |
Vitae Pharmaceuticals Llc |
Inhibitors of the menin-mll interaction
|
|
BR112019005337A2
(pt)
|
2016-09-19 |
2019-08-27 |
Mei Pharma Inc |
terapia combinada
|
|
TW201825465A
(zh)
|
2016-09-23 |
2018-07-16 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
|
WO2018057808A1
(en)
|
2016-09-23 |
2018-03-29 |
Gilead Sciences, Inc. |
Benzimidazole derivatives and their use as phosphatidylinositol 3-kinase inhibitors
|
|
TW201813963A
(zh)
|
2016-09-23 |
2018-04-16 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
|
IL265921B2
(en)
|
2016-10-14 |
2024-05-01 |
Prec Biosciences Inc |
Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome
|
|
US11590167B2
(en)
|
2016-12-03 |
2023-02-28 |
Juno Therapeutic, Inc. |
Methods and compositions for use of therapeutic T cells in combination with kinase inhibitors
|
|
ES2909234T3
(es)
*
|
2016-12-21 |
2022-05-05 |
Ono Pharmaceutical Co |
Compuestos de 6-amino-7,9-dihidro-8H-purin-8-ona como inhibidores de Brk
|
|
CN106588937B
(zh)
*
|
2017-01-16 |
2018-09-21 |
东莞市真兴贝特医药技术有限公司 |
咪唑并吡嗪类化合物及其制备方法和应用
|
|
EP3573989A4
(en)
|
2017-01-25 |
2020-11-18 |
Beigene, Ltd. |
CRYSTALLINE FORMS OF (S) -7- (1- (BUT-2-YNOYL) PIPERIDIN-4-YL) -2- (4-PHENOXYPHENYL) -4, 5, 6, 7-TETRAHY DROPYRAZOLO [1, 5-A ] PYRIMIDINE-3-CARBOXAMIDE, PREPARATION AND ASSOCIATED USES
|
|
TWI714820B
(zh)
|
2017-01-31 |
2021-01-01 |
美商基利科學股份有限公司 |
替諾福韋艾拉酚胺(tenofovir alafenamide)之晶型
|
|
JOP20180008A1
(ar)
|
2017-02-02 |
2019-01-30 |
Gilead Sciences Inc |
مركبات لعلاج إصابة بعدوى فيروس الالتهاب الكبدي b
|
|
US10314844B2
(en)
*
|
2017-02-24 |
2019-06-11 |
Gilead Sciences, Inc. |
Inhibitors of Bruton's tyrosine kinase
|
|
CN110312720A
(zh)
|
2017-02-24 |
2019-10-08 |
吉利德科学公司 |
布鲁顿氏酪氨酸激酶的抑制剂
|
|
JOP20180040A1
(ar)
|
2017-04-20 |
2019-01-30 |
Gilead Sciences Inc |
مثبطات pd-1/pd-l1
|
|
CN109111446B
(zh)
*
|
2017-06-22 |
2021-11-30 |
上海度德医药科技有限公司 |
一种具有药物活性的杂芳基化合物
|
|
AU2018290532A1
(en)
|
2017-06-26 |
2019-11-21 |
Beigene, Ltd. |
Immunotherapy for hepatocellular carcinoma
|
|
CN110997677A
(zh)
|
2017-08-12 |
2020-04-10 |
百济神州有限公司 |
具有改进的双重选择性的Btk抑制剂
|
|
CN111051305A
(zh)
|
2017-08-22 |
2020-04-21 |
吉利德科学公司 |
治疗性杂环化合物
|
|
WO2019108795A1
(en)
|
2017-11-29 |
2019-06-06 |
Beigene Switzerland Gmbh |
Treatment of indolent or aggressive b-cell lymphomas using a combination comprising btk inhibitors
|
|
KR102492115B1
(ko)
|
2017-12-20 |
2023-01-27 |
인스티튜트 오브 오가닉 케미스트리 앤드 바이오케미스트리 에이에스 씨알 브이.브이.아이. |
Sting 어댑터 단백질을 활성화하는 포스포네이트 결합을 가진 2'3' 사이클릭 다이뉴클레오티드
|
|
AU2018392213B2
(en)
|
2017-12-20 |
2021-03-04 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3' cyclic dinucleotides with phosphonate bond activating the STING adaptor protein
|
|
CA3087886A1
(en)
|
2018-01-19 |
2019-07-25 |
Idorsia Pharmaceuticals Ltd |
C5a receptor modulators
|
|
BR112020016466A2
(pt)
|
2018-02-13 |
2020-12-15 |
Gilead Sciences, Inc. |
Composto, composição farmacêutica, métodos para inibir pd-1, pd-l1 e/ou a interação de pd-1/pd-l1, para tratar câncer e para aprimorar a função de células-t em pacientes com hepatite b crônica (chb), e, kit para tratar ou prevenir câncer ou uma doença ou condição.
|
|
JP7050165B2
(ja)
|
2018-02-26 |
2022-04-07 |
ギリアード サイエンシーズ， インコーポレイテッド |
Ｈｂｖ複製阻害剤としての置換ピロリジン化合物
|
|
WO2019195181A1
(en)
|
2018-04-05 |
2019-10-10 |
Gilead Sciences, Inc. |
Antibodies and fragments thereof that bind hepatitis b virus protein x
|
|
TW202005654A
(zh)
|
2018-04-06 |
2020-02-01 |
捷克科學院有機化學與生物化學研究所 |
２，２，─環二核苷酸
|
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
|
TWI833744B
(zh)
|
2018-04-06 |
2024-03-01 |
捷克科學院有機化學與生物化學研究所 |
3'3'-環二核苷酸
|
|
US11142750B2
(en)
|
2018-04-12 |
2021-10-12 |
Precision Biosciences, Inc. |
Optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome
|
|
ES3035911T3
(en)
|
2018-04-19 |
2025-09-11 |
Gilead Sciences Inc |
Pd-1/pd-l1 inhibitors
|
|
US20210113568A1
(en)
|
2018-04-27 |
2021-04-22 |
Ono Pharmaceutical Co., Ltd. |
PREVENTIVE AND/OR THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASE COMPRISING COMPOUND HAVING Btk INHIBITORY ACTIVITY AS ACTIVE INGREDIENT
|
|
WO2019211799A1
(en)
|
2018-05-03 |
2019-11-07 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide
|
|
US11098027B2
(en)
|
2018-07-06 |
2021-08-24 |
Gilead Sciences, Inc. |
Therapeutic heterocyclic compounds
|
|
AU2019297428C1
(en)
|
2018-07-06 |
2023-03-23 |
Gilead Sciences, Inc. |
Therapeutic heterocyclic compounds
|
|
AU2019301811B2
(en)
|
2018-07-13 |
2022-05-26 |
Gilead Sciences, Inc. |
PD-1/PD-L1 inhibitors
|
|
WO2020028097A1
(en)
|
2018-08-01 |
2020-02-06 |
Gilead Sciences, Inc. |
Solid forms of (r)-11-(methoxymethyl)-12-(3-methoxypropoxy)-3,3-dimethyl-8-0x0-2,3,8,13b-tetrahydro-1h-pyrido[2,1-a]pyrrolo[1,2-c] phthalazine-7-c arboxylic acid
|
|
US20220362357A1
(en)
|
2018-08-31 |
2022-11-17 |
Stichting Radboud Universitair Medisch Centrum |
Synergistic Combinations of Amino Acid Depletion Agent Sensitizers (AADAS) and Amino Acid Depletion Agents (AADA), and Therapeutic Methods of Use Thereof
|
|
JP7158577B2
(ja)
|
2018-10-24 |
2022-10-21 |
ギリアード サイエンシーズ， インコーポレイテッド |
Ｐｄ－１／ｐｄ－ｌ１阻害剤
|
|
EP3873608A1
(en)
|
2018-10-31 |
2021-09-08 |
Gilead Sciences, Inc. |
Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity
|
|
AU2019372046B2
(en)
|
2018-10-31 |
2022-05-26 |
Gilead Sciences, Inc. |
Substituted 6-azabenzimidazole compounds as HPK1 inhibitors
|
|
EP3903828A4
(en)
|
2018-12-21 |
2022-10-05 |
Daiichi Sankyo Company, Limited |
ANTIBODY-DRUG CONJUGATE AND KINAS INHIBITOR COMBINATION
|
|
JP7350872B2
(ja)
|
2019-03-07 |
2023-09-26 |
インスティチュート オブ オーガニック ケミストリー アンド バイオケミストリー エーエスシーアール，ヴイ．ヴイ．アイ． |
３’３’－環状ジヌクレオチドおよびそのプロドラッグ
|
|
US12318403B2
(en)
|
2019-03-07 |
2025-06-03 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2′3′-cyclic dinucleotides and prodrugs thereof
|
|
EP3935065A1
(en)
|
2019-03-07 |
2022-01-12 |
Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. |
3'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator
|
|
EP3942045A1
(en)
|
2019-03-21 |
2022-01-26 |
Onxeo |
A dbait molecule in combination with kinase inhibitor for the treatment of cancer
|
|
TWI751517B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TWI751516B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
WO2020237025A1
(en)
|
2019-05-23 |
2020-11-26 |
Gilead Sciences, Inc. |
Substituted exo-methylene-oxindoles which are hpk1/map4k1 inhibitors
|
|
CN113939289A
(zh)
|
2019-06-10 |
2022-01-14 |
百济神州瑞士有限责任公司 |
一种含有布鲁顿氏酪氨酸激酶抑制剂的口服固体片剂及其制备方法
|
|
WO2020255038A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and pyridopyrimidine derivatives
|
|
MX2021015452A
(es)
|
2019-06-25 |
2022-02-11 |
Gilead Sciences Inc |
Proteinas de fusion flt3l-fc y metodos de uso.
|
|
WO2021011891A1
(en)
|
2019-07-18 |
2021-01-21 |
Gilead Sciences, Inc. |
Long-acting formulations of tenofovir alafenamide
|
|
WO2021034804A1
(en)
|
2019-08-19 |
2021-02-25 |
Gilead Sciences, Inc. |
Pharmaceutical formulations of tenofovir alafenamide
|
|
WO2021038540A1
(en)
|
2019-08-31 |
2021-03-04 |
Sun Pharma Advanced Research Company Limited |
Cycloalkylidene carboxylic acids and derivatives as btk inhibitors
|
|
KR20220074917A
(ko)
|
2019-09-30 |
2022-06-03 |
길리애드 사이언시즈, 인코포레이티드 |
Hbv 백신 및 hbv를 치료하는 방법
|
|
CA3154257A1
(en)
|
2019-10-14 |
2021-04-22 |
Principia Biopharma Inc. |
Methods for treating immune thrombocytopenia by administering (r)-2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile
|
|
KR20220098759A
(ko)
|
2019-11-08 |
2022-07-12 |
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) |
키나제 억제제에 대해 내성을 획득한 암의 치료 방법
|
|
CN116057068A
(zh)
|
2019-12-06 |
2023-05-02 |
精密生物科学公司 |
对乙型肝炎病毒基因组中的识别序列具有特异性的优化的工程化大范围核酸酶
|
|
CN120118089A
(zh)
|
2020-01-02 |
2025-06-10 |
迪哲(江苏)医药股份有限公司 |
Btk抑制剂
|
|
EP4093397A1
(en)
|
2020-01-20 |
2022-11-30 |
Genzyme Corporation |
Therapeutic tyrosine kinase inhibitors for relapsing multiple sclerosis (rms)
|
|
WO2021148581A1
(en)
|
2020-01-22 |
2021-07-29 |
Onxeo |
Novel dbait molecule and its use
|
|
AU2021209884A1
(en)
|
2020-01-22 |
2022-09-15 |
Principia Biopharma Inc. |
Crystalline forms of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile
|
|
AU2021237718B2
(en)
|
2020-03-20 |
2023-09-21 |
Gilead Sciences, Inc. |
Prodrugs of 4'-C-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same
|
|
PE20230779A1
(es)
|
2020-08-07 |
2023-05-09 |
Gilead Sciences Inc |
Profarmacos de analogos de nucleotidos de fosfonamida y su uso farmaceutico
|
|
TW202406932A
(zh)
|
2020-10-22 |
2024-02-16 |
美商基利科學股份有限公司 |
介白素2-Fc融合蛋白及使用方法
|
|
WO2022087422A1
(en)
|
2020-10-22 |
2022-04-28 |
Chulalongkorn University |
Pyrrolidine-3-carboxamide derivatives and related uses
|
|
WO2022121670A1
(zh)
|
2020-12-10 |
2022-06-16 |
苏州科睿思制药有限公司 |
Tolebrutinib的晶型及其制备方法和用途
|
|
WO2022140246A1
(en)
|
2020-12-21 |
2022-06-30 |
Hangzhou Jijing Pharmaceutical Technology Limited |
Methods and compounds for targeted autophagy
|
|
WO2022212893A1
(en)
|
2021-04-02 |
2022-10-06 |
Biogen Ma Inc. |
Combination treatment methods of multiple sclerosis
|
|
JP2024518558A
(ja)
|
2021-05-13 |
2024-05-01 |
ギリアード サイエンシーズ， インコーポレイテッド |
ＴＬＲ８調節化合物と抗ＨＢＶ ｓｉＲＮＡ治療薬との組合せ
|
|
WO2022242740A1
(zh)
*
|
2021-05-21 |
2022-11-24 |
杭州领业医药科技有限公司 |
Tolebrutinib盐及其晶型、其制备方法、其药物组合物和用途
|
|
CA3220923A1
(en)
|
2021-06-23 |
2022-12-29 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
|
EP4359413A1
(en)
|
2021-06-23 |
2024-05-01 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
|
CN117377671A
(zh)
|
2021-06-23 |
2024-01-09 |
吉利德科学公司 |
二酰基甘油激酶调节化合物
|
|
CN117355531A
(zh)
|
2021-06-23 |
2024-01-05 |
吉利德科学公司 |
二酰基甘油激酶调节化合物
|
|
CN118660705A
(zh)
*
|
2022-02-16 |
2024-09-17 |
贝达药业股份有限公司 |
一种药物组合物及所含活性成分化合物的制备方法
|
|
US11786531B1
(en)
|
2022-06-08 |
2023-10-17 |
Beigene Switzerland Gmbh |
Methods of treating B-cell proliferative disorder
|
|
WO2024037527A1
(en)
*
|
2022-08-16 |
2024-02-22 |
Beijing Neox Biotech Limited |
Btk degrading compounds
|
|
CN118027035A
(zh)
*
|
2022-11-14 |
2024-05-14 |
天津征程医药科技有限公司 |
作为btk抑制剂的嘌呤衍生物
|
|
WO2025240242A1
(en)
|
2024-05-13 |
2025-11-20 |
Gilead Sciences, Inc. |
Combination therapies with ribavirin
|
|
WO2025240246A1
(en)
|
2024-05-13 |
2025-11-20 |
Gilead Sciences, Inc. |
Combination therapies with ribavirin
|
|
US20250345389A1
(en)
|
2024-05-13 |
2025-11-13 |
Gilead Sciences, Inc. |
Combination therapies
|
|
US20250345390A1
(en)
|
2024-05-13 |
2025-11-13 |
Gilead Sciences, Inc. |
Combination therapies
|
|
CN118598781B
(zh)
*
|
2024-06-13 |
2025-06-10 |
迪嘉药业集团股份有限公司 |
一种孟鲁司特钠关键中间体的制备方法
|