CU20190056A7 - Ácidos carboxílicos de benzimidazoles y 4-aza, 5-aza, 7-aza y 4,7-diaza-benzimidazoles como agonistas receptores de glp-1, útiles para tratar o prevenir enfermedades cardiometabólicas - Google Patents
Ácidos carboxílicos de benzimidazoles y 4-aza, 5-aza, 7-aza y 4,7-diaza-benzimidazoles como agonistas receptores de glp-1, útiles para tratar o prevenir enfermedades cardiometabólicasInfo
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- aza
- benzimidazoles
- diaza
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Abstract
<p>La presente invención se refiere a 6 ácidos carboxílicos de benzimidazoles y 4-aza, 5-aza, 7-aza y 4,7-diaza-benzimidazoles como agonistas de GLP-1R, de fórmula general I:</p> <p>ESPACIO PARA LA FÓRMULA</p> <p>útiles en el tratamiento o prevención de enfermedades cardiometabólicas como diabetes, pre-diabetes, esteatohepatitis no alcohólica y enfermedad cardiovascular.</p>
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662435533P | 2016-12-16 | 2016-12-16 | |
| PCT/IB2017/057577 WO2018109607A1 (en) | 2016-12-16 | 2017-12-01 | Glp-1 receptor agonists and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20190056A7 true CU20190056A7 (es) | 2020-01-03 |
| CU24573B1 CU24573B1 (es) | 2022-01-13 |
Family
ID=60702906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2019000056A CU24573B1 (es) | 2016-12-16 | 2017-12-01 | Ácidos carboxílicos de benzimidazoles y 4-aza, 5-aza, 7-aza y 4,7-diaza-benzimidazoles como agonistas receptores de glp-1, útiles para tratar o prevenir enfermedades cardiometabólicas |
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| WO2010115736A2 (en) | 2009-04-02 | 2010-10-14 | Merck Serono S.A. | Dihydroorotate dehydrogenase inhibitors |
| KR101564806B1 (ko) * | 2010-05-13 | 2015-10-30 | 암젠 인크 | Ｐｄｅ10 저해제로서 유용한 질소 헤테로시클릭 화합물 |
| BR112013021236B1 (pt) | 2011-02-25 | 2021-05-25 | Merck Sharp & Dohme Corp | composto derivado de benzimidazol, e, composição |
| CR20190289A (es) | 2016-12-16 | 2019-08-21 | Pfizer | Agonistas receptores de glp-1 y usos de los mismos |
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