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CU20080114A7 - Emulsión intravenosa de butilftalida y aplicación de la misma - Google Patents

Emulsión intravenosa de butilftalida y aplicación de la misma

Info

Publication number
CU20080114A7
CU20080114A7 CU20080114A CU20080114A CU20080114A7 CU 20080114 A7 CU20080114 A7 CU 20080114A7 CU 20080114 A CU20080114 A CU 20080114A CU 20080114 A CU20080114 A CU 20080114A CU 20080114 A7 CU20080114 A7 CU 20080114A7
Authority
CU
Cuba
Prior art keywords
butilftalida
application
same
emulsion
intravenous
Prior art date
Application number
CU20080114A
Other languages
English (en)
Other versions
CU23814A3 (es
Inventor
Zhen Chen
Zhanqi Niu
Chunshun Zhao
Original Assignee
Shijiazhuang Pharma Group Nbp Pharmaceutical Co Lt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shijiazhuang Pharma Group Nbp Pharmaceutical Co Lt filed Critical Shijiazhuang Pharma Group Nbp Pharmaceutical Co Lt
Publication of CU20080114A7 publication Critical patent/CU20080114A7/es
Publication of CU23814A3 publication Critical patent/CU23814A3/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Esta invención presenta una emulsión intravenosa de butilftalida que se administra mediante infusión o inyección por vía intravenosa, la cual contiene butilftalida o derivados de ella como ingrediente activo en una cantidad de 0,01- 50 wt% y un excipiente en una cantidad de 50-90wt%, basados en el peso total de la emulsión.
CU20080114A 2005-12-16 2008-06-17 Emulsión intravenosa de butilftalida y aplicación de la misma CU23814A3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB2005101023552A CN100367951C (zh) 2005-12-16 2005-12-16 丁苯酞静脉乳剂及其应用

Publications (2)

Publication Number Publication Date
CU20080114A7 true CU20080114A7 (es) 2010-08-30
CU23814A3 CU23814A3 (es) 2012-06-21

Family

ID=36934680

Family Applications (1)

Application Number Title Priority Date Filing Date
CU20080114A CU23814A3 (es) 2005-12-16 2008-06-17 Emulsión intravenosa de butilftalida y aplicación de la misma

Country Status (13)

Country Link
US (2) US20090281177A1 (es)
EP (1) EP1970050B1 (es)
JP (2) JP5571311B2 (es)
KR (1) KR101061268B1 (es)
CN (1) CN100367951C (es)
AU (1) AU2006324219B2 (es)
BR (1) BRPI0619915B1 (es)
CA (1) CA2633170C (es)
CU (1) CU23814A3 (es)
EA (1) EA014518B1 (es)
IL (1) IL192169A (es)
UA (1) UA89315C2 (es)
WO (1) WO2007068212A1 (es)

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ES2609640T3 (es) * 2009-08-14 2017-04-21 Opko Health, Inc Formulaciones intravenosas de rolapitant
CN102178643B (zh) * 2011-04-29 2014-05-14 石药集团恩必普药业有限公司 一种丁苯酞或其衍生物的微乳透皮凝胶剂及其制备方法
CN107648222A (zh) * 2012-06-06 2018-02-02 石药集团中奇制药技术（石家庄）有限公司 一种丁苯酞药物活性组合物及其制备方法
CN103505409B (zh) * 2012-06-27 2017-12-26 石药集团中奇制药技术（石家庄）有限公司 一种丁苯酞注射液及其制备方法
CN103505414B (zh) * 2012-06-28 2017-08-08 石药集团恩必普药业有限公司 丁苯酞滴鼻剂及其制备方法
JP6552967B2 (ja) * 2013-02-06 2019-07-31 ホアン，ジンジュン 経口および非経口送達用のクロピドグレル遊離塩基の安定な医薬組成物
TWI547280B (zh) * 2014-04-24 2016-09-01 長弘生物科技股份有限公司 穩定醫藥組合物
CN105030760B (zh) 2014-04-24 2018-10-02 长弘生物科技股份有限公司 稳定医药组合物
CN119157850A (zh) * 2015-08-28 2024-12-20 康霈生技股份有限公司 用于减少局部脂肪的医药组成物及其用途
CN105796486A (zh) * 2016-03-17 2016-07-27 南京天翔医药科技有限公司 丁苯酞脂肪乳注射剂及其制备工艺
CN110101658B (zh) * 2018-02-01 2021-09-07 北京睿悦生物医药科技有限公司 丁苯酞脂微球注射液及其制备方法
CN110548004B (zh) * 2018-05-30 2023-05-16 成都施贝康生物医药科技有限公司 一种稳定的丁苯酞大容量注射液及其制备方法
CA3141337A1 (en) * 2019-05-24 2020-12-03 Piedmont Animal Health Inc. Long-acting injectable formulations and use thereof
CN111407725B (zh) * 2020-04-13 2024-07-19 中山大学 一种拉莫三嗪乳剂及其制备方法
CN114073694B (zh) * 2020-08-14 2024-03-12 北京科莱博医药开发有限责任公司 丁苯酞制剂及其制备方法
CN120478336A (zh) * 2021-04-01 2025-08-15 长春藤生物科技股份有限公司 正丁基苯酞的应用
CN114010595A (zh) * 2021-10-14 2022-02-08 山东诚创蓝海医药科技有限公司 一种丁苯酞乳剂及其制备方法
CN116407510B (zh) * 2021-12-29 2025-11-21 河北赛谱睿思医药科技有限公司 一种丁苯酞舌下片及其制备方法
CN114886848B (zh) * 2022-05-20 2024-03-08 山东泰合医药科技有限公司 一种纳米胶束组合物制备方法及制备的纳米胶束组合物
CN116459224A (zh) * 2023-05-15 2023-07-21 济南大学 一种丁苯酞纳米脂质体冻干粉针剂及其制备方法
CN116549388A (zh) * 2023-06-08 2023-08-08 华北制药集团新药研究开发有限责任公司 7-羟基-丁苯酞纳米乳制剂、其制备方法及应用
CN116942604A (zh) * 2023-08-16 2023-10-27 合肥亿帆生物制药有限公司 一种丁苯酞注射液及其制备方法

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Also Published As

Publication number Publication date
CU23814A3 (es) 2012-06-21
US20090281177A1 (en) 2009-11-12
IL192169A (en) 2016-02-29
CA2633170C (en) 2011-05-24
JP2012193206A (ja) 2012-10-11
US20110288167A1 (en) 2011-11-24
CA2633170A1 (en) 2007-06-21
BRPI0619915B1 (pt) 2021-06-01
BRPI0619915A2 (pt) 2011-10-25
JP5571311B2 (ja) 2014-08-13
EA200870060A1 (ru) 2009-02-27
AU2006324219B2 (en) 2010-03-04
KR101061268B1 (ko) 2011-08-31
EP1970050A1 (en) 2008-09-17
EP1970050A4 (en) 2009-12-09
IL192169A0 (en) 2008-12-29
JP2009519253A (ja) 2009-05-14
WO2007068212A1 (fr) 2007-06-21
CN1823729A (zh) 2006-08-30
KR20080091141A (ko) 2008-10-09
UA89315C2 (en) 2010-01-11
EA014518B1 (ru) 2010-12-30
CN100367951C (zh) 2008-02-13
EP1970050B1 (en) 2016-05-11
AU2006324219A1 (en) 2007-06-21
US10463614B2 (en) 2019-11-05

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