[go: up one dir, main page]

CR9595A - BENZOFURARONA DERIVATIVES AS NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS - Google Patents

BENZOFURARONA DERIVATIVES AS NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS

Info

Publication number
CR9595A
CR9595A CR9595A CR9595A CR9595A CR 9595 A CR9595 A CR 9595A CR 9595 A CR9595 A CR 9595A CR 9595 A CR9595 A CR 9595A CR 9595 A CR9595 A CR 9595A
Authority
CR
Costa Rica
Prior art keywords
benzofurarona
derivatives
progesterone receptors
steroid modulators
modulators
Prior art date
Application number
CR9595A
Other languages
Spanish (es)
Inventor
Schwede Wolfgang
Moeller Carsten
Schmidt Anja
Fuhrmann Ulrike
Schmees Norbert
Bothe Ulrich
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of CR9595A publication Critical patent/CR9595A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Furan Compounds (AREA)

Abstract

La presente invencion se refiere a moduladores no esteroides del receptor de progesterona de la formula general I, al proceso para su produccion, al uso de los moduladores del receptor de progesterona para la preparacion de agentes farmaceuticos asi como tambien composiciones farmaceuticas que contienen estos compuestos.The present invention relates to non-steroidal progesterone receptor modulators of the general formula I, to the process for their production, to the use of progesterone receptor modulators for the preparation of pharmaceutical agents as well as pharmaceutical compositions containing these compounds.

CR9595A 2005-06-24 2007-12-14 BENZOFURARONA DERIVATIVES AS NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS CR9595A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005030294A DE102005030294A1 (en) 2005-06-24 2005-06-24 Nonsteroidal progesterone receptor modulators

Publications (1)

Publication Number Publication Date
CR9595A true CR9595A (en) 2008-05-05

Family

ID=36716643

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9595A CR9595A (en) 2005-06-24 2007-12-14 BENZOFURARONA DERIVATIVES AS NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS

Country Status (22)

Country Link
EP (1) EP1899315A1 (en)
JP (1) JP2008543911A (en)
KR (1) KR20080018275A (en)
CN (1) CN101248056A (en)
AR (1) AR057409A1 (en)
AU (1) AU2006261049A1 (en)
BR (1) BRPI0612305A2 (en)
CA (1) CA2611900A1 (en)
CR (1) CR9595A (en)
DE (1) DE102005030294A1 (en)
DO (1) DOP2006000150A (en)
EA (1) EA200702604A1 (en)
EC (1) ECSP078043A (en)
GT (1) GT200600272A (en)
IL (1) IL188022A0 (en)
MX (1) MX2008000070A (en)
NO (1) NO20080441L (en)
PE (1) PE20070170A1 (en)
TW (1) TW200738665A (en)
UY (1) UY29626A1 (en)
WO (1) WO2006136462A1 (en)
ZA (1) ZA200800689B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY30805A1 (en) * 2006-12-21 2008-07-31 Bayer Schering Pharma Ag NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS
DE102007032800A1 (en) * 2007-07-10 2009-01-15 Bayer Schering Pharma Aktiengesellschaft Nonsteroidal progesterone receptor modulators
DE102007058747A1 (en) 2007-12-05 2009-06-10 Bayer Schering Pharma Aktiengesellschaft Nonsteroidal progesterone receptor modulators
TWI477276B (en) * 2008-04-28 2015-03-21 Repros Therapeutics Inc Antiprogestin dosing regimens
SG11201407397WA (en) 2012-05-31 2014-12-30 Repros Therapeutics Inc Formulations and methods for vaginal delivery of antiprogestins
JP6343619B2 (en) 2012-11-02 2018-06-13 レプロス セラピューティクス インコーポレイティド Methods and compositions for treating progesterone-dependent conditions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19723722A1 (en) * 1997-05-30 1998-12-10 Schering Ag Nonsteroidal progestogens
CN1353717A (en) * 1999-05-04 2002-06-12 莱加制药公司 Tetracyclic progesterone receptor modulator compounds and methods
US6358948B1 (en) * 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
JP2005519897A (en) * 2002-01-14 2005-07-07 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド Glucocorticoid mimetics, method for producing the same, pharmaceutical preparation containing the same, and use thereof
ES2280766T3 (en) * 2002-03-11 2007-09-16 Bayer Schering Pharma Aktiengesellschaft 5- (2-HIDROXI-3'-1- (3-TRIFLUOROMETILFENIL) -CICLOPROPIL) -PROPIONILAMINO) -FTALIDA AND RELATED COMPOUNDS WITH MODULATING ACTIVITY OF THE PROGESTERONE RECEIVER, FOR USE IN FERTILITY CONTROL AND REPLACEMENT THERAPY.
DE10346939A1 (en) * 2003-10-06 2005-05-19 Schering Ag New arylalkanol derivatives used for treating e.g. respiratory diseases, joint diseases, vascular inflammations, skin disorders, kidney and liver diseases and neurological diseases

Also Published As

Publication number Publication date
PE20070170A1 (en) 2007-03-02
EP1899315A1 (en) 2008-03-19
ECSP078043A (en) 2008-01-23
DOP2006000150A (en) 2006-12-31
DE102005030294A1 (en) 2007-01-04
AU2006261049A1 (en) 2006-12-28
JP2008543911A (en) 2008-12-04
IL188022A0 (en) 2008-03-20
CN101248056A (en) 2008-08-20
ZA200800689B (en) 2009-07-29
AR057409A1 (en) 2007-12-05
KR20080018275A (en) 2008-02-27
TW200738665A (en) 2007-10-16
CA2611900A1 (en) 2006-12-28
MX2008000070A (en) 2008-03-19
UY29626A1 (en) 2007-01-31
BRPI0612305A2 (en) 2010-11-03
NO20080441L (en) 2008-03-07
EA200702604A1 (en) 2008-06-30
GT200600272A (en) 2007-08-20
WO2006136462A1 (en) 2006-12-28

Similar Documents

Publication Publication Date Title
CR10922A (en) DERIVATIVES OF INDOL AS RECEIVING ANTAGONISTS OF S1P1
SV2010003580A (en) NEW AGONISTS OF GLUCOCORTICOID RECEPTORS
ECSP11011348A (en) 2-MERCAPTOQUINOLIN-3-SUBSTITUTED CARBOXAMIDS AS MODULATORS OF KCNQ2 / 3
CR9814A (en) CARBOXAMIDE DERIVATIVES AS ANTAGONISTS OF THE MUSCARINIC RECEIVER
ECSP088623A (en) DERIVATIVES OF AZEPINOINDOL AS PHARMACEUTICAL AGENTS
CR11623A (en) COMPOUNDS
ECSP066856A (en) NEW COMPOUNDS AS OPIOID RECEIVER MODULATORS
CR10497A (en) USEFUL PIPERAZINYL DERIVATIVES IN THE TREATMENT OF DISEASES MEDIATED BY THE GPR38 RECEIVER
ECSP099338A (en) DERIVATIVES OF CARBYXYCLIC ACID (IHL) ACID (IHL) CHINICLIDINE AS MUSCARINIC RECEIVER ANTAGONISTS
CO6351723A2 (en) DERIVATIVES OF PIRAZOLO- [5,1-B] -OXAZOL AS AN ANTIGONIST OF CRF1
UY32744A (en) DERIVATIVES OF 2-CARBOXAMIDA-7-PIPERAZINIL-BENZOFURANO 774
ECSP11011345A (en) 2-MERCAPTO-3-AMINOPIRIDINE REPLACED AS MODULATORS OF KCNQ2 / 3
ECSP11011346A (en) 3-Amino-2-mercaptoquinoline substituted as a modulator of KCNQ2 / 3
CR9595A (en) BENZOFURARONA DERIVATIVES AS NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS
CR11171A (en) NEW LIGHTING COMPOUNDS OF THE ADENOSINE A3 RECEIVER
CR20190379A (en) Estrogen receptor modulators
NI201100015A (en) NOVEL COMPOUNDS ACTIVE AS MUSCARINIC RECEPTOR ANTAGONISTS.
CO6531479A2 (en) DERIVATIVES OF SPIROMACTAM AND USE OF THE SAME
ECSP10010200A (en) PIRAZOL DERIVATIVES AS 5-LO INHIBITORS
UY31338A1 (en) NEW NOVEDOUS COMPOUNDS AS ANTAGONISTS OF MUSCARINIC RECEPTORS
ECSP067028A (en) STEROID PROPHARMS WITH ANDROGENIC ACTION
UY31428A1 (en) 1,2,4-TRIAZOL THIOPHEN DERIVATIVES FUSED AS MODULATORS OF MGLUR5
UY29817A1 (en) NEW AZETIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PREPARATION PROCESSES AND THERAPEUTIC USE OF THEM.
CU23564A3 (en) CARBOXAMIDE DERIVATIVES AS ANTAGONISTS OF THE MUSCARINIC RECEIVER
CR11790A (en) QUINUCLIDINE DERIVATIVES AS M3 MUSCARINIC RECEPTORS ANTAGONISTS

Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)