CN1679661A - Medicine for treating female mazoplasia and preparation thereof - Google Patents
Medicine for treating female mazoplasia and preparation thereof Download PDFInfo
- Publication number
- CN1679661A CN1679661A CN 200410033146 CN200410033146A CN1679661A CN 1679661 A CN1679661 A CN 1679661A CN 200410033146 CN200410033146 CN 200410033146 CN 200410033146 A CN200410033146 A CN 200410033146A CN 1679661 A CN1679661 A CN 1679661A
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- Prior art keywords
- medicine
- rhizoma
- radix
- curcumae
- treatment
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- 239000003814 drug Substances 0.000 title claims abstract description 46
- 229940079593 drug Drugs 0.000 title claims description 11
- 238000002360 preparation method Methods 0.000 title claims description 8
- 239000002775 capsule Substances 0.000 claims abstract description 9
- 230000002265 prevention Effects 0.000 claims description 8
- 241000218176 Corydalis Species 0.000 claims description 6
- 241000411851 herbal medicine Species 0.000 claims description 6
- 210000005075 mammary gland Anatomy 0.000 claims description 6
- 210000000582 semen Anatomy 0.000 claims description 6
- 230000035755 proliferation Effects 0.000 claims description 5
- 241000522620 Scorpio Species 0.000 claims description 4
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 4
- 239000009490 scorpio Substances 0.000 claims description 4
- 241000628997 Flos Species 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 2
- 241000196324 Embryophyta Species 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 244000003416 Asparagus officinalis Species 0.000 abstract 1
- 235000005340 Asparagus officinalis Nutrition 0.000 abstract 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 1
- 244000179560 Prunella vulgaris Species 0.000 abstract 1
- 241001530126 Scrophularia Species 0.000 abstract 1
- 230000000249 desinfective effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000007493 shaping process Methods 0.000 abstract 1
- 238000007873 sieving Methods 0.000 abstract 1
- 210000000481 breast Anatomy 0.000 description 19
- 208000002193 Pain Diseases 0.000 description 10
- 230000000694 effects Effects 0.000 description 9
- 206010006272 Breast mass Diseases 0.000 description 6
- 235000012054 meals Nutrition 0.000 description 6
- 206010062717 Increased upper airway secretion Diseases 0.000 description 5
- 230000002146 bilateral effect Effects 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 208000026435 phlegm Diseases 0.000 description 5
- 206010006298 Breast pain Diseases 0.000 description 4
- 208000006662 Mastodynia Diseases 0.000 description 4
- 230000008034 disappearance Effects 0.000 description 4
- 239000005556 hormone Substances 0.000 description 3
- 229940088597 hormone Drugs 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 230000003213 activating effect Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000008451 emotion Effects 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 239000004753 textile Substances 0.000 description 2
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 201000008275 breast carcinoma Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000009313 farming Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000008361 herbal raw material Substances 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 230000004630 mental health Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000036651 mood Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 230000032696 parturition Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
A Chinese medicine 'Rubao capsule' or 'Rubao bra' for treating mastoplasia of woman is prepared from 11 Chinese-medicinal materials including prunella spike, oyster shell, scrophularia root, asparagus root, etc through proportional mixing, grinding, sieving, disinfecting and high-pressure shaping.
Description
One, technical field
The present invention relates to the preparation method of the medicine of a kind of treatment and prevention female mammary gland proliferation.
Two, background technology
The hyperplasia of mammary glands disease belongs to the dialectical category of motherland's traditional medicine " nodules of the breast ", and it is many because of damaged by excess of seven emotions, depression of liver-QI, QI-blood circulation are smooth, phlegm-damp is tied mutually, stagnating is disease to fall ill.Cardinal symptom be women oneself lay one's hand on and one-sided or bilateral breast in size, tuberosity that how many degree depths are different are arranged.Also there are many women oneself not know that the state of an illness needs the health check-up generaI investigation just to learn.Most women occur together before menstrual onset distending pain of the breast, fidgety, sx or the disappearance after row of mood, mastalgia slightly or does not not bitterly have periodically at ordinary times, good sending out in giving birth to the high age bracket of vigorous hormonal readiness in 20-40 year.This disease often influences women's physical and mental health and life and work as if untimely healing, the tendency that with the passing of time oriented bad disease (breast carcinoma) transforms.To the prevention of cyclomastopathy, medicament categories is many, but only limits to oral medication at present.
Three, summary of the invention
The purpose of this invention is to provide a kind of Orally taken and externally and develop simultaneously, the curative effect of working along both lines is reliable, and adaptability is strong, is specifically designed to the pure Chinese herbal medicine of treatment and prevention cyclomastopathy.
Another object of the present invention provides the preparation method of treatment cyclomastopathy medicine.Contain herbal raw material ratio prescriptions in accordance with regulations such as Spica Prunellae, Concha Ostreae, Radix Scrophulariae, Radix Asparagi, Bulbus Fritillariae Thunbergii, Radix Curcumae, Semen Vaccariae, rhizoma sparganic, Rhizoma Curcumae, Rhizoma Cyperi, corydalis tuber in the Chinese herb medicine of the present invention's treatment and prevention cyclomastopathy, the weight proportion of described each composition following (unit is gram)
Fructus Trichosanthis 30-45g rhizoma sparganic 15-20g Fructus Toosendan 20-30g
Rhizoma Chuanxiong 20-30g Rhizoma Curcumae 15-20g Caulis Spatholobi 30-40g
Flos Carthami 10-15g Radix Curcumae 20-30g Bulbus Fritillariae Thunbergii 30-60g
Semen Vaccariae 30-40g Radix Platycodonis 10-15g Spica Prunellae 60-80g
Rhizoma Cyperi 15-20g Even sticks up 15-30g Herba Taraxaci 30-45g
Rhizoma Dioscoreae Bulbiferae 10-20g Concha Ostreae 40-60g Scorpio 20-30g
The red Radix Paeoniae Alba 30-40g of corydalis tuber 20-30g Radix Asparagi 30-40g
Radix Scrophulariae 60-80g Fructus Aurantii 30-40g
The preparation method that the present invention relates to a kind of treatment and prevention female mammary gland proliferation medicine is to incapsulate and make the medicine cover after the said herbal medicine thing is ground not, sieves, mixes, sterilizes to form by quantitative package.
Medicine of the present invention is from traditional Chinese medical science viewpoint, thinks that the pathogenic factor of cyclomastopathy is except with damaged by excess of seven emotions, depression of liver-QI, QI-blood circulation are smooth, phlegm-damp is tied mutually, stagnate to sick relevant, also relevant with women's hormone in vivo off-leveling simultaneously.At 20-40 year period of duration women's pathogenic factor and disease performance, choose have hard masses softening and resolving, the Chinese herbal medicine of activating QI to eliminate phlegm, removing obstruction in the collateral to relieve pain, the horizontal effect of adjusting women hormone in vivo, rigorous prescription.
The performance that relates to Chinese herbal medicine in the pharmaceutical formulation of the present invention is: Spica Prunellae, Fructus Trichosanthis, Bulbus Fritillariae Thunbergii, Fructus Toosendan hard masses softening and resolving reduce phlegm, and going stagnates is principal agent, rhizoma sparganic, Rhizoma Curcumae, Rhizoma Dioscoreae Bulbiferae, Caulis Spatholobi, the red Radix Paeoniae Alba, corydalis tuber, Scorpio, it is up for the pharmacy of holding concurrently, Radix Platycodonis, Semen Vaccariae, Rhizoma Chuanxiong medicine carrying that removing obstruction in the collateral to relieve pain is adjuvant, Radix Asparagi, Radix Ophiopogonis, Radix Curcumae, Herba Taraxaci diminishing inflammation and resolving masses, and through sick institute mediation lactiferous ducts is for drawing and medicine.The mutual compatibility of said medicine through strictness processing fill capsule and medicine cover Orally taken and externally, has the effect of hard masses softening and resolving, activating QI to eliminate phlegm, removing obstruction in the collateral to relieve pain, adjusting women hormone in vivo level.
Using method:
A: Rubao capsule three times on the one, a 3-5 grain taking medicine after meal (every contains crude drug 0.1g) was a course of treatment in 30-60 days.
B: newborn precious medicine cover: circular textile sheet, diameter 8-10cm, weight 20-30g are put into each one of two breast brassiere, and 15-30 days is a course of treatment.
The advantage of drug use of the present invention is: external application develops simultaneously, and the curative effect of working along both lines is reliable, and adaptability is strong, is specifically designed to the pure Chinese herbal medicine of treatment and prevention cyclomastopathy.
In order to prove that medicine of the present invention has the effect of treatment cyclomastopathy, the cyclomastopathy patient of the bright Yong of selection of clinical 120 example diagnosis is divided into treatment group and each 60 example of matched group at random by patient's wish.(the 1-3 month) treatment group gives Rubao capsule three times on the one in the treatment time of regulation, and a 3-5 grain taking medicine after meal (every contains crude drug 0.1g) adds with newborn precious medicine cover and puts into each one of two breast brassiere, and 15-30 days is a course of treatment.
Efficacy assessment standard: cure, breast nodule is subdued mastalgia and is disappeared.Produce effects, breast nodule does not disappear, but mastalgia disappears.Invalid, breast nodule and pain ditto do not have improvement.
Experimental result: 60 routine total effective rates 86.6% are organized in treatment, cure 31 examples, 21 examples that take a turn for the better, and treatment time is 30-60 days, matched group 60 examples, total effective rate 60.5% is cured 27 examples, and 8 examples take a turn for the better.Two groups of total effects significant differences, treatment group clinical effectiveness is apparently higher than matched group.Follow up a case by regular visits to nontoxic pair of effect and untoward reaction.
Medical record is given an example:
1, Lin: Altay City paper mill, 39 years old Chinese Xinjiang of women, accounting.April 27 calendar year 2001 because of conscious bilateral breast before row distending pain through back disappearance, show effect repeatedly, March is surplus to check UP and does B ultrasonic and the two breast scannings of infrared ray, pin and inhale breast nodule cytolgical examination Yong and examine and be cyclomastopathy, come my institute to go to a doctor and give Rubao capsule three times on the one, a 3-5 grain taking medicine after meal (every contains crude drug 0.1g), add with newborn precious medicine cover and put into each one of two breast brassiere, one course of treatment of medication, treatment back transference cure, tuberosity is subdued distending pain of the breast and is disappeared in the bilateral breast.Do not recur with anti-after 1 year.
2, Wang: woman 27 years old, Bei Tun forest farm, Xinjiang cadre, on March 14th, 2002 examined and is cyclomastopathy because of Physical Check-Ups (two newborn B ultrasonic scannings, noctovisor scan, pin are inhaled the breast nodule inspection) Yong.Conscious right breast distending pain can be touched bar hitch joint, tenderness is obvious, come my institute to go to a doctor and give Rubao capsule three times on the one, a 3-5 grain taking medicine after meal (every contains crude drug 0.1g), add with newborn precious medicine cover and put into each one of two breast brassiere, tuberosity is subdued the distending pain of the breast disappearance in the transference cure after medicine for treatment 15-30 days, bilateral breast.Do not recur with anti-after 1 year.
3, Lee: woman 23 years old, 181 cadres of Xinjiang Bei Tun farming ten teachers because of conscious right breast distending pain can be touched bar hitch joint, tenderness obviously comes me to examine prescription on individual diagnosis by gate, inhale the breast nodule inspection through two newborn B ultrasonic scannings, noctovisor scan, pin) Yong examines and is cyclomastopathy.Give Rubao capsule three times on the one, a 3-5 grain taking medicine after meal (every contains crude drug 0.1g) adds with newborn precious medicine cover and puts into each one of two breast brassiere, and 15-30 days is a course of treatment, and tuberosity is subdued the distending pain of the breast disappearance in the transference cure after the medicine for treatment, bilateral breast.Do not recur with anti-after 1 year.
Four, the specific embodiment:
According to components by weight percent, choose:
Fructus Trichosanthis 30g rhizoma sparganic 15g Fructus Toosendan 20g
Rhizoma Chuanxiong 20g Rhizoma Curcumae 15g Caulis Spatholobi 30g
Flos Carthami 10g Radix Curcumae 20g Bulbus Fritillariae Thunbergii 30g
Semen Vaccariae 30g Radix Platycodonis 10g Spica Prunellae 60g
Rhizoma Cyperi 15g Even sticks up 15g Herba Taraxaci 30g
Rhizoma Dioscoreae Bulbiferae 10g Concha Ostreae 40g Scorpio 20g
The red Radix Paeoniae Alba 30g of corydalis tuber 20g Radix Asparagi 30g
Radix Scrophulariae 60g Fructus Aurantii 30g
The preparation method that the present invention relates to the medicine of a kind of treatment and prevention female mammary gland proliferation is to incapsulate and make the medicine cover after said medicine is ground not, sieved, mixes, sterilizes to form by quantitative package.
When treatment is used:
A: with medicine Rubao capsule of the present invention three times on the one, a 3-5 grain taking medicine after meal (every contains crude drug 0.1g) was a course of treatment in 30-60 days.
B: newborn precious medicine cover: circular textile sheet, diameter 8-10cm, weight 20-3g are put into each one of two breast brassiere, and 15-30 days is a course of treatment.
Claims (1)
1, plants the Chinese herbal and crude drugs preparations of treatment and prevention female mammary gland proliferation, form (Rubao capsule and newborn precious medicine cover) through strict processing and manufacturing.They include Chinese herbal medicine such as Spica Prunellae, Concha Ostreae, Radix Scrophulariae, Radix Asparagi, Bulbus Fritillariae Thunbergii, Radix Curcumae, Semen Vaccariae, rhizoma sparganic, Rhizoma Curcumae, Rhizoma Cyperi, corydalis tuber, it is characterized in that, be to make by following step:
The parts by weight proportioning of wherein said each composition is (unit is gram):
Fructus Trichosanthis 30g rhizoma sparganic 15g Fructus Toosendan 20g
Rhizoma Chuanxiong 20g Rhizoma Curcumae 15g Caulis Spatholobi 30g
Flos Carthami 10g Radix Curcumae 20g Bulbus Fritillariae Thunbergii 30g
Semen Vaccariae 30g Radix Platycodonis 10g Spica Prunellae 60g
Rhizoma Cyperi 15g Even sticks up 15g Herba Taraxaci 30g
Rhizoma Dioscoreae Bulbiferae 10g Concha Ostreae 40g Scorpio 20g
The red Radix Paeoniae Alba 30g of corydalis tuber 20g Radix Asparagi 30g
Radix Scrophulariae 60g Fructus Aurantii 30g
Preparation method is to incapsulate and make the medicine cover after said medicine is ground not, sieved, mixes, sterilizes to form by quantitative package.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100331462A CN100418570C (en) | 2004-04-07 | 2004-04-07 | Medicine for treating female mazoplasia and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100331462A CN100418570C (en) | 2004-04-07 | 2004-04-07 | Medicine for treating female mazoplasia and preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1679661A true CN1679661A (en) | 2005-10-12 |
| CN100418570C CN100418570C (en) | 2008-09-17 |
Family
ID=35066667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100331462A Expired - Fee Related CN100418570C (en) | 2004-04-07 | 2004-04-07 | Medicine for treating female mazoplasia and preparation thereof |
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| Country | Link |
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| CN (1) | CN100418570C (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100374147C (en) * | 2006-02-17 | 2008-03-12 | 徐樊 | Traditional Chinese medicine preparation for treating mammary gland hyperplasia |
| CN101244177B (en) * | 2008-03-21 | 2010-06-23 | 朱霞 | Rupisan medicine and preparation thereof |
| CN101143162B (en) * | 2007-09-03 | 2010-09-01 | 马海龙 | Medicinal liquor for treating mastoproliferation and its preparing process |
| CN101337044B (en) * | 2008-08-20 | 2010-12-01 | 刘芳 | External preparation for mammary gland disease and preparation method thereof |
| CN101134080B (en) * | 2006-08-30 | 2011-09-07 | 瑞普（天津）生物药业有限公司 | Compound traditional Chinese powder medicine for treating acute mastitis for cows |
| CN101757521B (en) * | 2008-12-25 | 2011-11-23 | 刘桂荫 | Traditional Chinese medicine for treating proliferation of mammary gland |
| CN102908562A (en) * | 2012-11-05 | 2013-02-06 | 贵州苗珍堂生物科技有限公司 | Traditional Chinese medicine combination for treating breast diseases and preparation method thereof |
| CN103734920A (en) * | 2013-12-17 | 2014-04-23 | 张月婵 | Green herbal medicine bra |
| CN105106852A (en) * | 2015-09-17 | 2015-12-02 | 李朕 | Traditional Chinese medicine preparation for treating hyperplasia of mammary glands and breast cancer |
| CN105168345A (en) * | 2015-08-14 | 2015-12-23 | 殷永洲 | Chinese herbal medicine combination for treating breast cancer |
| CN105288503A (en) * | 2015-12-03 | 2016-02-03 | 苏州枫灵医药科技有限公司 | Pharmaceutic preparation for treating nodules of breasts |
| CN105853913A (en) * | 2016-04-28 | 2016-08-17 | 张传水 | External plaster for treating hyperplasia of mammary glands |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1205948C (en) * | 2002-01-18 | 2005-06-15 | 屈旭 | A kind of internal medicine for treating mammary gland hyperplasia |
-
2004
- 2004-04-07 CN CNB2004100331462A patent/CN100418570C/en not_active Expired - Fee Related
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100374147C (en) * | 2006-02-17 | 2008-03-12 | 徐樊 | Traditional Chinese medicine preparation for treating mammary gland hyperplasia |
| CN101134080B (en) * | 2006-08-30 | 2011-09-07 | 瑞普（天津）生物药业有限公司 | Compound traditional Chinese powder medicine for treating acute mastitis for cows |
| CN101143162B (en) * | 2007-09-03 | 2010-09-01 | 马海龙 | Medicinal liquor for treating mastoproliferation and its preparing process |
| CN101244177B (en) * | 2008-03-21 | 2010-06-23 | 朱霞 | Rupisan medicine and preparation thereof |
| CN101337044B (en) * | 2008-08-20 | 2010-12-01 | 刘芳 | External preparation for mammary gland disease and preparation method thereof |
| CN101757521B (en) * | 2008-12-25 | 2011-11-23 | 刘桂荫 | Traditional Chinese medicine for treating proliferation of mammary gland |
| CN102908562A (en) * | 2012-11-05 | 2013-02-06 | 贵州苗珍堂生物科技有限公司 | Traditional Chinese medicine combination for treating breast diseases and preparation method thereof |
| CN102908562B (en) * | 2012-11-05 | 2015-02-11 | 贵州苗珍堂生物科技有限公司 | Traditional Chinese medicine combination for treating breast diseases and preparation method thereof |
| CN103734920A (en) * | 2013-12-17 | 2014-04-23 | 张月婵 | Green herbal medicine bra |
| CN105168345A (en) * | 2015-08-14 | 2015-12-23 | 殷永洲 | Chinese herbal medicine combination for treating breast cancer |
| CN105106852A (en) * | 2015-09-17 | 2015-12-02 | 李朕 | Traditional Chinese medicine preparation for treating hyperplasia of mammary glands and breast cancer |
| CN105288503A (en) * | 2015-12-03 | 2016-02-03 | 苏州枫灵医药科技有限公司 | Pharmaceutic preparation for treating nodules of breasts |
| CN105853913A (en) * | 2016-04-28 | 2016-08-17 | 张传水 | External plaster for treating hyperplasia of mammary glands |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100418570C (en) | 2008-09-17 |
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Granted publication date: 20080917 |