CN1223362C - Chinese medicine composition for treating colitis - Google Patents
Chinese medicine composition for treating colitis Download PDFInfo
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- CN1223362C CN1223362C CN 02138144 CN02138144A CN1223362C CN 1223362 C CN1223362 C CN 1223362C CN 02138144 CN02138144 CN 02138144 CN 02138144 A CN02138144 A CN 02138144A CN 1223362 C CN1223362 C CN 1223362C
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- chinese medicine
- medicine composition
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- 239000003814 drug Substances 0.000 title claims abstract description 24
- 239000000203 mixture Substances 0.000 title claims abstract description 13
- 206010009887 colitis Diseases 0.000 title claims abstract description 8
- 239000002775 capsule Substances 0.000 claims description 6
- 241001038563 Pseudostellaria Species 0.000 claims description 5
- 239000008361 herbal raw material Substances 0.000 claims description 2
- 239000002552 dosage form Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 12
- 208000002193 Pain Diseases 0.000 abstract description 6
- 241000411851 herbal medicine Species 0.000 abstract description 3
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 abstract description 3
- 206010061218 Inflammation Diseases 0.000 abstract description 2
- 230000008030 elimination Effects 0.000 abstract description 2
- 238000003379 elimination reaction Methods 0.000 abstract description 2
- 230000023597 hemostasis Effects 0.000 abstract description 2
- 241000131766 Caryopteris incana Species 0.000 abstract 3
- 231100000331 toxic Toxicity 0.000 abstract 2
- 230000002588 toxic effect Effects 0.000 abstract 2
- 241000132012 Atractylodes Species 0.000 abstract 1
- 241000612166 Lysimachia Species 0.000 abstract 1
- 241001077898 Melanthera Species 0.000 abstract 1
- 241001664510 Saussurea costus Species 0.000 abstract 1
- 235000006784 Saussurea lappa Nutrition 0.000 abstract 1
- 230000003260 anti-sepsis Effects 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 208000035861 hematochezia Diseases 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 210000000952 spleen Anatomy 0.000 description 7
- 206010012735 Diarrhoea Diseases 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 239000012467 final product Substances 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 4
- 210000002784 stomach Anatomy 0.000 description 4
- 229940079593 drug Drugs 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
- 206010009900 Colitis ulcerative Diseases 0.000 description 2
- 201000006704 Ulcerative Colitis Diseases 0.000 description 2
- 208000019790 abdominal distention Diseases 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 230000002757 inflammatory effect Effects 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- GSDSWSVVBLHKDQ-UHFFFAOYSA-N 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Chemical class FC1=CC(C(C(C(O)=O)=C2)=O)=C3N2C(C)COC3=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-UHFFFAOYSA-N 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 208000002881 Colic Diseases 0.000 description 1
- 208000005016 Intestinal Neoplasms Diseases 0.000 description 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-N Salicylic acid Natural products OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 1
- 208000032023 Signs and Symptoms Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical class C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 229940124599 anti-inflammatory drug Drugs 0.000 description 1
- 239000003212 astringent agent Substances 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 201000002313 intestinal cancer Diseases 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- -1 salicylic acid sulfapyridine class Chemical class 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to a Chinese medicine composition for treating colitis, which is characterized in that the Chinese medicine composition comprises caryopteris incana, saussurea lappa clarke, fructus toosendan, heterophylla falsestarwort, stirred largehead atractylodes rhizome, Halloysitum Rubrum, etc. The Chinese herbal medicine, caryopteris incana, also called square stem lysimachia, is the main component in the formula. The caryopteris incana has the favorable functions of antisepsis anti-inflammation, heat and toxic material clearing, hemostasis, pain alleviating and pus and blood stool elimination in records. The formula has the advantages of reasonable combination, obvious curative effect, unique medicine selection and no obvious side and toxic effects. 86 clinical tests prove that the Chinese medicine composition takes effect on 93 % of patients who take the Chinese medicine composition for a first course, and the cure rate reaches 65.3%.
Description
Technical field
The present invention relates to Chinese medicine composition, exactly is the Chinese medicine composition of treatment colitis.
Background technology
Though chronic colitis, chronic ulcerative colitis are the highest with American-European countries's sickness rate; Also be the commonly encountered diseases of China, frequently-occurring disease.Wherein ulcerative colitis and intestinal cancer has a substantial connection, also becomes one of national healthy disease of harm.At present, healing clinically still acquires a certain degree of difficulty, and does not have specific drug, and easily outbreak repeatedly is one of common difficult disease.The report of relevant integrative therapy is a lot of in recent years, Western medicine is used antibiosis anti-inflammatory drugs such as salicylic acid sulfapyridine class, ofloxacin class, amoxicillin class always, though the part curative effect is arranged, radical rate is low, easily recurrence, wherein some Western medicine life-time service easily develops immunity to drugs and side effect.
The often unfixing prescription of Chinese traditional treatment, clinical many with heat-clearing and toxic substances removing, relieving diarrhea with astringents, regulating QI to relieve pain, invigorating the spleen to clear away damp pathogen, therapies such as blood circulation promoting and blood stasis dispelling, determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs often can alleviate partial symptoms, but produce effects is slower, need take medicine for a long time, radical rate is low, uses inconvenience, also imperfect therapy.Chinese patent medicine is used Spleen Invigorating and Intestine Tonifying Pill, JIECHANGYAN WAN, the intestines and stomach Yiganning capsule etc. always.
Summary of the invention
Through studying for a long period of time, provide the Chinese medicine composition of the treatment colitis that a kind of therapeutic effect is good, radical rate is high, have no side effect.
Drug regimen composition formula of the present invention following (herbal raw material with the quality proportioning is formed):
Herba caryopteridis nepetaefoliae 40～60 Radix Aucklandiae (Radix Vladimiriae) 5～15
Fructus Toosendan 5～15 Radix Pseudostellariaes 5～15
Rhizoma Atractylodis Macrocephalae (parched) 5～15 Halloysitum Rubrums 3～7
Rhizoma Zingiberis 3～7
The main component of the present invention's prescription is the Chinese herbal medicine Herba caryopteridis nepetaefoliae, the side of having another name called stalk Herba Lysimachiae, and tool is put down in writing this medicine good anti-inflammation, heat-clearing and toxic substances removing, hemostasis and pain-relieving, blood circulation promoting and blood stasis dispelling, reduce inflammatory exudation, eliminate bloody purulent stool, the reparation and the healing effect of cleaning and promotion intestinal mucosa ulcer surface.Adjuvant Radix Pseudostellariae invigorating the spleen and replenishing QI, nourishing YIN to lower pathogenic fire; The Halloysitum Rubrum astringing to arrest diarrhea; The Rhizoma Atractylodis Macrocephalae (parched) spleen reinforcing is good for the stomach, dampness removing and diarrhea-relieving; Fructus Toosendan, Radix Aucklandiae (Radix Vladimiriae) regulating QI to relieve pain, the effect of elimination abdominal distention; Rhizoma Zingiberis warming spleen and stomach for dispelling cold and stomach and alleviating pain, its effect warm in nature is compatible with single flower Herba caryopteridis nepetaefoliae's effect cool in nature, can send out better therapeutic.
Symptoms such as because of inflammatory stimulus, the patient has enterospasm, stomachache, times of defecation to increase, and it is more than to have loose bowels, Radix Aucklandiae (Radix Vladimiriae), Fructus Toosendan have regulating QI to relieve pain, eliminate the effect of stomachache, abdominal distention, alleviation intestinal colic.
The traditional Chinese medical science thinks that chronic diarrhea must be empty, thus with the Radix Pseudostellariae invigorating the spleen and replenishing QI, nourishing YIN to lower pathogenic fire, auxilliary Rhizoma Atractylodis Macrocephalae (parched) invigorating the spleen to clear away damp pathogen, Halloysitum Rubrum is held back intestinal antidiarrheal and is helped it.
Chinese medicine composition formula and prescription of the present invention is reasonable, and curative effect is more outstanding, selects medicine unique, no obvious toxic-side effects.Through 86 routine clinical verifications, 93% patient gets final product produce effects in first course of treatment of taking medicine, and cure rate reaches 65.3%.
The Chinese herbal medicine Herba caryopteridis nepetaefoliae is distributed more widely on the south the Changjiang river, aboundresources, but also establishing in large scale, and cultivation does not need special cultivation technique.All the other adjuvants are medicine commonly used.
The present invention can be made into capsule, and technology is simple, and is cheap for manufacturing cost.
The specific embodiment
Embodiment 1:
Take off the row raw material
Herba caryopteridis nepetaefoliae 400 Radix Aucklandiae (Radix Vladimiriae) 50
Fructus Toosendan 50 Radix Pseudostellariaes 50
Rhizoma Atractylodis Macrocephalae (parched) 50 Halloysitum Rubrums 30
Rhizoma Zingiberis 30
Pulverize and get final product in incapsulating after fine ground.Every capsules content of dispersion 0.5g.
Using method: oral, be grown up each 20, the child is cut down according to the circumstance, and three times on the one, one month is a course of treatment, and lapse on the state of an illness total course of treatment decides.
Embodiment 2:
Take off the row raw material
Herba caryopteridis nepetaefoliae 500 Radix Aucklandiae (Radix Vladimiriae) 70
Fructus Toosendan 70 Radix Pseudostellariaes 80
Rhizoma Atractylodis Macrocephalae (parched) 60 Halloysitum Rubrums 40
Rhizoma Zingiberis 40
Making capsule by example 1 gets final product.
Embodiment 3:
Take off the row raw material
Herba caryopteridis nepetaefoliae 600 Radix Aucklandiae (Radix Vladimiriae) 70
Fructus Toosendan 60 Radix Pseudostellariaes 80
Rhizoma Atractylodis Macrocephalae (parched) 70 Halloysitum Rubrums 60
Rhizoma Zingiberis 60
Making capsule by example 1 gets final product.
Claims (2)
1, the Chinese medicine composition of treatment colitis is characterized in that: be made up of the herbal raw material of following quality proportioning
5～15 parts of 40～60 portions of Radix Aucklandiae (Radix Vladimiriae) of Herba caryopteridis nepetaefoliae
5～15 parts of 5～15 parts of Radix Pseudostellariaes of Fructus Toosendan
3～7 parts of 5～15 parts of Halloysitum Rubrums of Rhizoma Atractylodis Macrocephalae (parched)
3～7 parts of Rhizoma Zingiberiss.
2, the Chinese medicine composition of treatment colitis according to claim 1 is characterized in that: the dosage form of described pharmaceutical composition is a capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02138144 CN1223362C (en) | 2002-08-17 | 2002-08-17 | Chinese medicine composition for treating colitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02138144 CN1223362C (en) | 2002-08-17 | 2002-08-17 | Chinese medicine composition for treating colitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1401378A CN1401378A (en) | 2003-03-12 |
| CN1223362C true CN1223362C (en) | 2005-10-19 |
Family
ID=4749311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02138144 Expired - Fee Related CN1223362C (en) | 2002-08-17 | 2002-08-17 | Chinese medicine composition for treating colitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1223362C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104623610A (en) * | 2015-02-26 | 2015-05-20 | 王燕 | Heat-clearing and dampness-resolving preparation for treating enteritis and preparation method thereof |
-
2002
- 2002-08-17 CN CN 02138144 patent/CN1223362C/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| CN1401378A (en) | 2003-03-12 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |