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CN1088370C - Tongguan Shugan ointment and its preparation method - Google Patents

Tongguan Shugan ointment and its preparation method Download PDF

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CN1088370C
CN1088370C CN98104834A CN98104834A CN1088370C CN 1088370 C CN1088370 C CN 1088370C CN 98104834 A CN98104834 A CN 98104834A CN 98104834 A CN98104834 A CN 98104834A CN 1088370 C CN1088370 C CN 1088370C
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ointment
milk
medicine
plaster
preparation
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CN1223127A (en
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韩钰
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Abstract

A Chinese medicine in the form of plaster for treating hepatism is prepared from musk, bezoar, asafetida, Dragon's blood, croton seed, white mustard seed, amomum fruit, bupleurum root, oriental wormwood, etc through preparing plaster with milk, and sticking it to liver.

Description

通关舒肝膏及制备方法Tongguan Shugan ointment and its preparation method

本发明涉及一种治疗肝炎病的药物,具体地说是以中药为原料制备的药物,本发明还涉及该药物的制备方法。The invention relates to a medicine for treating hepatitis, in particular a medicine prepared from traditional Chinese medicine, and also relates to a preparation method of the medicine.

肝病是严重危害人类健康的一种疾病,它不仅具有传染性,而且不宜治愈,因此患有此病的人不仅自身感到痛苦,而且给周围人带来极大精神负担。Liver disease is a disease that seriously endangers human health. It is not only contagious, but also unsuitable for cure. Therefore, people suffering from this disease not only feel pain themselves, but also bring great mental burden to those around them.

为治疗该病,现已有不少医务工作者为之付出努力,除市面上已销售的药物外,专利申请91106266和91109404均分别公布了一种速效肝炎灵的配置方法,和速治肝炎口服液配制方法,这两种药物均以中草药为原料加工而成药,它们均有一定的疗效,但均为口服药物。In order to treat this disease, many medical workers have made great efforts for it. In addition to the drugs sold on the market, patent applications 91106266 and 91109404 have respectively announced a preparation method of quick-acting Ganyanling, and oral medicine for quick-curing hepatitis. Liquid preparation method, these two kinds of medicines are all processed into medicine with Chinese herbal medicine as raw materials, they all have certain curative effect, but all are oral medicines.

本发明的目的是提供一种能直接作用于肝区,能免去病人吃药之苦且渗透力强的治疗肝病的外用药物。The purpose of the present invention is to provide an externally used medicine for treating liver disease which can directly act on the liver area, save the patient from taking the medicine, and has strong penetrating power.

本发明的另一目的是提供该药的制备方法。Another object of the present invention is to provide a preparation method of the medicine.

本发明的解决方案是基于祖国医学对肝病的认识及治疗原则,参考现代药理研究的成就,从中药宝库中筛选出具有扶正固本,凉血活血,理气养阴,清热利湿,解毒祛邪,芳香化浊的天然药物组成,并加以特有的制作工艺,制造而成。The solution of the present invention is based on the understanding and treatment principles of liver disease in Chinese medicine, and with reference to the achievements of modern pharmacological research, from the treasury of traditional Chinese medicines, it screens out the medicines with the functions of strengthening the body, cooling blood and promoting blood circulation, regulating qi and nourishing yin, clearing away heat and dampness, detoxifying and eliminating pathogenic factors. , aromatized and turbid natural medicine composition, and with a unique production process, it is manufactured.

本发明是由下列药物组份制备而成(用量为重量份):The present invention is prepared from the following pharmaceutical components (amounts are parts by weight):

麝香 0.5-5份                牛黄   0.3-3份Musk 0.5-5 parts Bezoar 0.3-3 parts

阿魏 10-67.5份              血竭   10-67.5份Asafoetida 10-67.5 servings Blood jerky 10-67.5 servings

巴豆 7.5-60份               白芥子 15-80份Croton 7.5-60 parts White Mustard Seed 15-80 parts

砂仁 1.5-9份                柴胡   20-80份Amomum 1.5-9 parts Bupleurum 20-80 parts

茵陈 20-80份                奶     84-496份Yinchen 20-80 parts Grandma 84-496 parts

制备本发明药物的配方优选重量份配比范围是:The preferred proportioning range of parts by weight of the formula for preparing the medicine of the present invention is:

麝香 0.8-3份              牛黄   0.5-2份Musk 0.8-3 parts Bezoar 0.5-2 parts

阿魏 10-45份              血竭   10-45份Asafoetida 10-45 servings Blood jerky 10-45 servings

巴豆 10-37.5份            白芥子 20-50份Croton 10-37.5 parts White Mustard Seed 20-50 parts

砂仁 1.5-7份              柴胡   25-70份Amomum 1.5-7 parts Bupleurum 25-70 parts

茵陈 25-65份              奶     102-359份Yinchen 25-65 parts Grandma 102-359 parts

将上述各组份制成本药物的生产方法是:The production method that above-mentioned each component is made into this medicine is:

(1)取配方中所规定量的麝香、牛黄粉碎成能过100-120目筛的细粉。(1) Get musk and bezoar of the prescribed amount in the formula and pulverize into fine powder that can pass through a 100-120 mesh sieve.

(2)取配方中规定量的巴豆,将其去皮留用白仁,再称取配方中规定量的阿魏、血竭、白芥子、砂仁、茵陈、柴胡,将这些药物共同粉碎至能过100-120目筛的细粉。(2) Take the specified amount of croton in the formula, peel it and keep the white kernels, then weigh the specified amount of ferulicum, blood jellyfish, white mustard seed, amomum, capillary, and Bupleurum, and crush these drugs together To a fine powder that can pass through a 100-120 mesh sieve.

(3)把两次加工成的细粉合在一起,并混合均匀。(3) Combine the fine powders processed twice and mix them evenly.

(4)在给病人医治使用前将上述药粉用配量中的奶调制均匀后分摊在布上,制成膏药,每块膏药的药物重量为100-200克,药物摊放直径10-15公分。(4) Before the patient is treated and used, the above-mentioned medicated powder is prepared evenly with the milk in the dose and spread on the cloth to make a plaster. The medicine weight of each plaster is 100-200 grams, and the diameter of the medicine is 10-15 centimeters .

膏药中药物调制所用的奶以人奶最佳。The milk used for the preparation of the medicine in the plaster is best with human milk.

医治时先用生姜清理肝区,再将制成的膏药敷上,使用4-8小时,用过的膏药的药物可加奶重复再用,对病人连续用药时间为8天,而后休息七天,每半个月为一个疗程,根据病情掌握需治疗的疗程数。When treating, first use ginger to clean the liver area, then apply the plaster made, and use it for 4-8 hours. The used plaster can be used repeatedly with milk. The continuous medication time for the patient is 8 days, and then rest for 7 days. Every half a month is a course of treatment, and the number of courses of treatment required is mastered according to the condition.

采用此种药物治疗肝病,免去了病人吃药之苦,药物直接贴于经生姜清理过的肝区,因此便于药物的渗入和对肝病的治疗。Using this medicine to treat liver disease saves patients the pain of taking medicine, and the medicine is directly pasted on the liver area cleaned by ginger, so it is convenient for the penetration of medicine and the treatment of liver disease.

为了表明本发明对肝病的治疗效果,从1992-1997年本发明对1523例病人进行了临床观察,其中男性患者1297人,女性患者226人,按年龄分组为:20岁以下53人,21-35岁428人,36-50岁409人,51-60岁320人,60岁以上313人;按病史分组为:8年以下的患者为789人,8-15年的患者为624人,15年以上患者为110人;按病型分组为:甲型189人,乙型1229人,非甲、非乙型109人。上述病人均为医院检查、确诊的患者。In order to show the therapeutic effect of the present invention on liver disease, the present invention has carried out clinical observation to 1523 routine patients from 1992-1997, wherein male patient 1297 people, female patient 226 people, grouped by age: 53 people under 20 years old, 21- 428 people were 35 years old, 409 people were 36-50 years old, 320 people were 51-60 years old, and 313 people were over 60 years old; grouped by medical history: 789 patients under 8 years old, 624 patients 8-15 years old, 15 There were 110 patients over 100 years old; grouped by disease type: 189 patients with type A, 1229 patients with type B, and 109 patients with non-A or non-B type. The above-mentioned patients are all patients who have been examined and diagnosed by the hospital.

治疗期间停用其他任何治疗肝病的药物,仅贴用本发明所制备的药物。During the treatment, stop using any other medicines for treating liver diseases, and only paste the medicines prepared by the present invention.

治疗情况为:    肝病类型     甲型     乙型 非甲、乙型  治疗人数(人)     187     1229     109     显效率     99%     98%     97%     治愈率     98%     90%     93% Treatment conditions are: type of liver disease Type A Type B Non-A, B Number of people treated (person) 187 1229 109 Significant efficiency 99% 98% 97% cure rate 98% 90% 93%

治疗标准为:The standard of treatment is:

1、病症消失。1. The symptoms disappeared.

2、肝区无压痛或叩击痛。2. No tenderness or percussion pain in the liver area.

3、检查证明肝功能恢复正常。3. Examination proves that the liver function has returned to normal.

4、乙型肝病患者HBeAg转阴。4. HBeAg turned negative in patients with hepatitis B disease.

对上述患者进行治疗过程中,在使用本发明5个疗程后,对病人询问,得出:所有病人不再有乏力、恶心、厌油、腹胀、肝区疼痛等自觉症状,饮食睡眠恢复正常。During the treatment process of the above-mentioned patients, after using the present invention for 5 courses of treatment, the patients were inquired, and it was found that all patients no longer had subjective symptoms such as fatigue, nausea, oily, abdominal distension, pain in the liver area, and their diet and sleep returned to normal.

实施例1:Example 1:

按下列配方及配量称取原料:Weigh the raw materials according to the following formula and proportion:

麝香 0.5千克            牛黄   0.3千克Musk 0.5 kg Bezoar 0.3 kg

阿魏 4.5千克            血竭   4.5千克Asafoetida 4.5 kg Blood jerky 4.5 kg

巴豆 4.5千克            白芥子 7.5千克Croton 4.5 kg White Mustard Seed 7.5 kg

砂仁 0.9千克            柴胡   8千克Amomum 0.9 kg Bupleurum 8 kg

茵陈 7.5千克            奶     36千克Capsicum chen 7.5 kg milk 36 kg

按下述方法制造:Manufactured as follows:

把按配方中要求量的麝香、牛黄粉碎至能过100目筛的细粉,取配方中要求量的巴豆,将其去皮留用白仁,称取配方中要求量的阿魏、血竭、砂仁、茵陈、柴胡,将它们共同粉碎至能过100目筛的细粉,而后把两次加工成的细粉混合均匀,将上述药物用配方中量的奶调和,而后摊于布上,制成膏药,每块膏药含药量为200克,膏药直径为15公分,用奶调和工序在使用前进行。Grind musk and bezoar according to the amount required in the formula to a fine powder that can pass through a 100-mesh sieve, get the amount of croton required in the formula, peel it and keep the white kernels, and take the amount of Ferulicum, dried blood, Amomum, Capsicum chinensis, and Bupleurum chinensis are crushed together to fine powder that can pass through a 100-mesh sieve, and then the fine powder processed twice is mixed evenly, and the above-mentioned medicine is mixed with the amount of milk in the formula, and then spread on the cloth Go up, make plaster, and every piece of plaster contains 200 grams of medicine, and the diameter of plaster is 15 centimeters, and is carried out before using with milk reconciling operation.

实施例2:按下列配量称取原料:Embodiment 2: take raw material by following proportioning:

麝香 0.25千克            牛黄   0.2千克Musk 0.25 kg Bezoar 0.2 kg

阿魏 3千克               血竭   3千克Asafoetida 3kg Blood Dried Blood 3kg

巴豆 2.5千克             白芥子 4.5千克Croton 2.5 kg White Mustard Seed 4.5 kg

砂仁 0.25千克            柴胡   4千克Amomum 0.25kg Bupleurum 4kg

茵陈 2.9千克             人奶   12千克Capsicum chen 2.9kg Human milk 12kg

把按配方中要求量的麝香、牛黄粉碎至120目的细粉,将配方中的巴豆去皮留用白仁,称取配方中重量的阿魏和血竭,再称取配方中规定量的砂仁、茵陈、柴胡,将它们共同粉碎至120目的细粉,而后把两次加工成的细粉混合均匀,在使用前把上述药物制成的粉剂用配方中规定量的人奶调和均匀,摊于布上,制成直径为12公分、重量为100克的膏药。Grind musk and bezoar according to the amount required in the formula to 120 mesh fine powder, peel off the croton in the formula and keep the white kernels, weigh the ferulicum and dried blood in the formula, and then weigh the amomum in the specified amount in the formula , Capsicum chinensis, Bupleurum chinensis, crush them together to 120-mesh fine powder, then mix the fine powder processed twice, and mix the powder made of the above-mentioned medicine with the prescribed amount of human milk in the formula before use, Spread it on the cloth to make a plaster with a diameter of 12 centimeters and a weight of 100 grams.

Claims (5)

1, a kind of Tongguanshugan ointment for the treatment of hepatopathy is characterized in that: medicine that it is contained and consumption weight portion thereof are:
Moschus 0.5-5 part Calculus Bovis 0.3-3 part
Resina Ferulae 10-67.5 part Sanguis Draxonis 10-67.5 part
Fructus Crotonis 7.5-60 part Semen Sinapis Albae 15-80 part
Fructus Amomi 1.5-9 part Radix Bupleuri 20-80 part
Herba Artemisiae Scopariae 20-80 part milk 84-496 part.
2, the Tongguanshugan ointment of treatment hepatopathy according to claim 1 is characterized in that: medicine that it is contained and consumption weight portion are:
Moschus 0.8-3 part Calculus Bovis 0.5-2 part
Resina Ferulae 10-45 part Sanguis Draxonis 10-45 part
Fructus Crotonis 10-37.5 part Semen Sinapis Albae 20-50 part
Fructus Amomi 1.5-7 part Radix Bupleuri 25-70 part
Herba Artemisiae Scopariae 25-65 part milk 102-359 part.
3, a kind of preparation method of Tongguanshugan ointment as claimed in claim 1 or 2 is characterized in that:
A, the Moschus of getting defined weight portion in the prescription, bovine calculus powder are broken to the fine powder that can cross the 100-120 mesh sieve;
B, get the Fructus Crotonis of predetermined weight part in the prescription again, Bai Ren is continued to employ in its peeling, take by weighing Resina Ferulae, Sanguis Draxonis, Fructus Amomi, Herba Artemisiae Scopariae, the Radix Bupleuri of ormal weight in the prescription again, they are crushed to the fine powder that can cross the 100-120 mesh sieve jointly;
C, the fine powder that is processed into for twice is lumped together, and mix homogeneously, cure to patient use before with above-mentioned medicated powder with prescription in the milk of ormal weight modulate, and spread out on cloth, make plaster.
4, according to the preparation method of the described Tongguanshugan ointment of claim 3, it is characterized in that; The weight of every plaster contained drug is the 100-200 gram, and it is the 10-15 centimetre that its plaster medicine spreads diameter.
5, the preparation method of Tongguanshugan ointment according to claim 4 is characterized in that: the used milk of preparation plaster is people's milk.
CN98104834A 1998-01-15 1998-01-15 Tongguan Shugan ointment and its preparation method Expired - Fee Related CN1088370C (en)

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CN98104834A CN1088370C (en) 1998-01-15 1998-01-15 Tongguan Shugan ointment and its preparation method

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNB001160486A Division CN1150919C (en) 2000-09-22 2000-09-22 Paste for eradicating liver disease and preparing method

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CN1223127A CN1223127A (en) 1999-07-21
CN1088370C true CN1088370C (en) 2002-07-31

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102406859B (en) * 2011-12-01 2014-07-23 张玉芹 External traditional Chinese medicine composition for treating hepatitis B
CN109125415A (en) * 2018-11-03 2019-01-04 杜文建 A kind of external application Chinese medicine patch and preparation method thereof for treating hepatopathy

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1063819A (en) * 1991-02-05 1992-08-26 王柱亭 Formula of Kezeng ointment
CN1076628A (en) * 1993-02-12 1993-09-29 宋美琼 Yuer ointment

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1063819A (en) * 1991-02-05 1992-08-26 王柱亭 Formula of Kezeng ointment
CN1076628A (en) * 1993-02-12 1993-09-29 宋美琼 Yuer ointment

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
吉林中医药1983,(4) 1983.4.30 郭广义等防治肝炎中草药研究近况 *
吉林中医药1983,(4) 1983.4.30 郭广义等防治肝炎中草药研究近况;山东中医学院学报1988,12(4) 1988.4.30 任日君 安宫牛黄丸研究概况 *
山东中医学院学报1988,12(4) 1988.4.30 任日君 安宫牛黄丸研究概况 *

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