CN1375282A - Micron level Chinese medicine powder and its prepn. - Google Patents
Micron level Chinese medicine powder and its prepn. Download PDFInfo
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- CN1375282A CN1375282A CN 01106567 CN01106567A CN1375282A CN 1375282 A CN1375282 A CN 1375282A CN 01106567 CN01106567 CN 01106567 CN 01106567 A CN01106567 A CN 01106567A CN 1375282 A CN1375282 A CN 1375282A
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- 239000003814 drug Substances 0.000 title claims abstract description 155
- 239000000843 powder Substances 0.000 title claims abstract description 68
- 239000000203 mixture Substances 0.000 claims abstract description 87
- 238000000034 method Methods 0.000 claims abstract description 79
- 239000000126 substance Substances 0.000 claims abstract description 11
- 239000008187 granular material Substances 0.000 claims abstract description 8
- 239000000284 extract Substances 0.000 claims description 71
- 238000001035 drying Methods 0.000 claims description 60
- 229940079593 drug Drugs 0.000 claims description 41
- 238000002360 preparation method Methods 0.000 claims description 37
- 238000010298 pulverizing process Methods 0.000 claims description 30
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 14
- 238000011156 evaluation Methods 0.000 claims description 11
- 238000003756 stirring Methods 0.000 claims description 7
- 238000000605 extraction Methods 0.000 claims description 6
- 238000001802 infusion Methods 0.000 claims description 6
- 238000000194 supercritical-fluid extraction Methods 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 238000005325 percolation Methods 0.000 claims description 5
- 229910052756 noble gas Inorganic materials 0.000 claims description 4
- 239000012567 medical material Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 4
- 238000000227 grinding Methods 0.000 abstract description 3
- 235000019580 granularity Nutrition 0.000 abstract 2
- 230000002860 competitive effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000002604 ultrasonography Methods 0.000 abstract 1
- 241001619461 Poria <basidiomycete fungus> Species 0.000 description 10
- 241000756943 Codonopsis Species 0.000 description 6
- 239000010231 banlangen Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 235000003935 Hippophae Nutrition 0.000 description 4
- 241000229143 Hippophae Species 0.000 description 4
- 239000009636 Huang Qi Substances 0.000 description 4
- 241000180649 Panax notoginseng Species 0.000 description 4
- 235000003143 Panax notoginseng Nutrition 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 210000000582 semen Anatomy 0.000 description 4
- 210000000952 spleen Anatomy 0.000 description 4
- 241000208340 Araliaceae Species 0.000 description 3
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 3
- 235000003140 Panax quinquefolius Nutrition 0.000 description 3
- 241000209140 Triticum Species 0.000 description 3
- 235000021307 Triticum Nutrition 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 235000008434 ginseng Nutrition 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 240000001008 Dimocarpus longan Species 0.000 description 2
- 235000000235 Euphoria longan Nutrition 0.000 description 2
- 241000222640 Polyporus Species 0.000 description 2
- 239000008862 fructus schizandrae, radix ginseng, radix ophiopogonis drug combination Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- 239000008843 wulingsan Substances 0.000 description 2
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000007159 enucleation Effects 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
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- 239000007787 solid Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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Abstract
The present invention has opened a medicinal powder of micron Chinese medicine and its preparing method to the public. The method is to identify, process and dry Chinese medicine crop or Chinese medicine compound firstly and then to grind them into granules as granularities of bigger than one micron but smaller than seventy five micron by ultrasound of ultramicro grinding method after they bieng preground or medicinal effectiveness matters being picked up, to dry then again, to classify them according to the size of granularity and to general blend them for obtaining the final medicinal powder of micron Chinese medicine. The invented medicinal power can raise biological utilization rate and curative effect, keep substance basis of medicinal effectiveness, save resources of Chinese medicine crop and help to enhance the competitive force of Chinese medicine on the international medicine market.
Description
The present invention relates to Chinese medicine preparation and preparation method thereof, more specifically relate to micron Chinese medicine powder and preparation method thereof.
Chinese medicine and Chinese medicine preparation thereof are traditional rarities of the Chinese nation, for the prosperity of the Chinese nation has been made indelible contribution.Chinese powder medicine is a kind of Chinese medicine preparation commonly used, the following method of the general employing of the processing of existing Chinese powder medicine, at first carry out Chinese crude drug or herbal mixture evaluation, the process of preparing Chinese medicine, drying, carrying out conventional Chinese crude drug then pulverizes or extracts, or after extracting the active ingredient of herbal mixture, again by making Chinese powder medicine after classification, total the mixing.The powder that this processing mode is made, its weak point is that the effective ingredient availability of Chinese crude drug or herbal mixture is low, curative effect is not high, onset is slower, dose is big, the processing added value is low, be unfavorable for that Chinese medicine steps into international medical main flow market, and limited natural resources of Chinese medicinal materials is utilized insufficient, particularly unfortunate to the waste of some rare natural resources of Chinese medicinal materials.
Micron Chinese medicine powder is meant the powder made from micron Chinese medicine or micron herbal mixture or Chinese medicine micron extract or herbal mixture micron extract.
Micron Chinese medicine is meant that the Chinese crude drug granularity is greater than 1 micron and less than 75 microns Chinese crude drug ultramicro powder.
The micron herbal mixture is meant that its granularity of herbal mixture is greater than 1 micron and less than 75 microns herbal mixture ultramicro powder.
Chinese medicine micron extract is meant that the granularity of Chinese crude drug through extracting the resulting extract of effective substance is greater than 1 micron and less than 75 microns Chinese crude drug extract.
Herbal mixture micron extract is meant that the granularity of herbal mixture through extracting the resulting extract of effective substance is greater than 1 micron and less than 75 microns herbal mixture extract.
The objective of the invention is to make micron Chinese medicine powder, and its preparation method is provided with micron Chinese medicine or micron herbal mixture or Chinese medicine micron extract or herbal mixture micron extract.Micron Chinese medicine powder can be improved the absorbance and the curative effect of Chinese medicine or herbal mixture effective substance, can reduce dose, and improves biological availability, saves Chinese material medicine resource.
In order to achieve the above object, the present invention makes micron Chinese medicine powder with micron Chinese medicine or micron herbal mixture or Chinese medicine micron extract or herbal mixture micron extract, and its preparation method adopts following technical scheme:
Choose Chinese crude drug or herbal mixture, earlier through evaluation, the process of preparing Chinese medicine, drying, then it is ground into micron Chinese medicine or micron herbal mixture or is ground into Chinese medicine micron extract or herbal mixture micron extract after extracting effective substance, drying, classification, total mixing are made micron Chinese medicine powder again.
The present invention compared with prior art has following advantage:
1, since the granularity of micron Chinese medicine or micron herbal mixture or Chinese medicine micron extract or herbal mixture micron extract greater than 1 micron and less than 75 microns, particle diameter does not relate to the aspect of atom and molecular structure in this scope, so do not influence the original Chinese medicine attribute of effective substance, pharmacodynamic properties substantially and cure mainly function, but this particle size range can make most of crude drug cell breaking cellular walls, therefore, micron Chinese medicine powder can improve biological availability.
2, the diffusion rate of release owing to solid drugs is directly proportional with its area, and the granularity of micron Chinese medicine or micron herbal mixture or Chinese medicine micron extract or herbal mixture micron extract is significantly smaller than existing Chinese crude drug and Chinese crude drug extract, thereby its surface area and drug solubility have been increased greatly, therefore, after the micron Chinese medicine powder made from micron Chinese medicine or micron herbal mixture or Chinese medicine micron extract or herbal mixture micron extract is taken, more convenient and rapid in the intravital absorption of people, make curative effect higher, can improve clinical therapeutic efficacy effectively.
3, because of of the raising of micron Chinese medicine powder than Chinese medicine powder medicine effective substance availability, can reduce the use amount of Chinese crude drug, extenuate growing Chinese crude drug demand and the contradiction between tight market and resource, limited Chinese material medicine resource is utilized fully.
4, because micron Chinese medicine powder has above advantage, can improve the surcharge of Chinese crude drug greatly, make commensurability Chinese material medicine resource obtain better economic benefit.
5, same drug effect, micron Chinese medicine powder is compared with Chinese medicine powder can reduce dose, thereby more easily accepted by people, and the competitiveness of Chinese medicine in the international market improved in the easier international market that enters.
Fig. 1 is the block diagram of micron Chinese medicine powder preparation method of the present invention.
Do further according to the preparation method of accompanying drawing to micron level Chinese medicine powder of the present invention below Bright.
Micron level Chinese medicine powder of the present invention has following 5 kinds of preparation methods, is now narrated respectively.
First kind of preparation method:
1, the evaluation of Chinese medicine or herbal mixture is in order to confirm the true of Chinese medicine or herbal mixture Puppet and quality;
2, the process of preparing Chinese medicine is to concoct by the concocting method of traditional Chinese medicine;
3, drying is that Chinese medicine or herbal mixture after concocting are carried out drying;
4, precomminution is to Chinese medicine or herbal mixture powder after processing through the above method Broken machine is pulverized, and makes its granularity reach 76 microns to 800 microns;
5, ultramicro grinding be with air-flow crushing, ball mill grinding, vibration pulverizing, Ultrasonic Pulverization, Stir to pulverize, one of them breaking method or two kinds of breaking methods wherein of centrifugal pulverizing In conjunction with, Chinese medicine or herbal mixture are made granularity greater than 1 micron and little less than 75 microns Rice Chinese medicine or micron herbal mixture;
6, drying;
7, classification is that above-mentioned micron Chinese medicine or micron herbal mixture are divided by the size of granularity Level;
It is 8, total mixed that to make powder all be to be undertaken by traditional handicraft.
The second preparation method:
1, Chinese medicine or herbal mixture identify it is in order to confirm the true and false of Chinese medicine or herbal mixture And quality;
2, the process of preparing Chinese medicine is to concoct by the concocting method of traditional Chinese medicine;
3, drying is that Chinese medicine or herbal mixture after concocting are carried out drying;
4, precomminution is that Chinese crude drug or herbal mixture after handling through the above method are pulverized with pulverizer, makes its granularity reach 76 microns to 800 microns;
5, extract be to the Chinese crude drug after the precomminution or herbal mixture by adding the solvent-water or the ethanol of 4～10 times of its weight, adopt infusion process or percolation or circumfluence method or extraction to extract the effective substance of Chinese crude drug or herbal mixture;
6, be condensed into clear paste or thick paste, relative density is 1.2-1.6, drying;
7, micronizing be with comminution by gas stream, ball mill pulverizing, vibrant pulverization, Ultrasonic Pulverization, stirring pulverize, one of them breaking method or the wherein combination of two kinds of breaking methods of centrifugal pulverizing, Chinese crude drug extract or herbal mixture extract are made granularity greater than 1 micron and less than 75 microns Chinese medicine micron extract or herbal mixture micron extract;
8, drying;
9, classification is that above-mentioned Chinese medicine micron extract or herbal mixture micron extract are carried out classification by the size of granularity;
It is 10, total mixed that to make powder all be to be undertaken by traditional handicraft.
The third preparation method:
1, the evaluation of Chinese crude drug or herbal mixture is the true and false and the quality in order to confirm Chinese crude drug or herbal mixture;
2, the process of preparing Chinese medicine is to concoct by the concocting method of traditional Chinese crude drug;
3, drying is that Chinese medicine or herbal mixture after concocting are carried out drying;
4, extract be to Chinese crude drug or herbal mixture by adding the solvent-water or the ethanol of 4～10 times of its weight, adopt infusion process or percolation or circumfluence method or extraction to extract the effective substance of Chinese crude drug or herbal mixture.
5, be condensed into clear paste or thick paste, relative density is 1.2-1.6, drying;
6, micronizing be with comminution by gas stream, ball mill pulverizing, vibrant pulverization, Ultrasonic Pulverization, stirring pulverize, one of them breaking method or the wherein combination of two kinds of breaking methods of centrifugal pulverizing, Chinese crude drug extract or herbal mixture extract are made granularity greater than 1 micron and less than 75 microns Chinese medicine micron extract and herbal mixture micron extract;
7, drying;
8, classification is that above-mentioned Chinese medicine micron extract or herbal mixture micron extract are carried out classification by the size of granularity;
It is 9, total mixed that to make powder all be to be undertaken by traditional handicraft.
The 4th kind of preparation method:
1, the evaluation of Chinese crude drug or herbal mixture is the true and false and the quality in order to confirm Chinese crude drug or herbal mixture;
2, the process of preparing Chinese medicine is to concoct by the concocting method of traditional Chinese crude drug;
3, drying is that Chinese medicine or herbal mixture after concocting are carried out drying;
4, precomminution is that Chinese crude drug or herbal mixture after handling through the above method are pulverized with pulverizer, and making its granularity is 76 microns to 800 microns;
5, supercritical fluid extraction is by medium-CO
2Or noble gas extracts, and obtains granularity greater than 1 micron and less than 75 microns Chinese medicine micron extract or herbal mixture micron extract;
6, drying;
7, classification is that above-mentioned Chinese medicine micron extract or herbal mixture micron extract are carried out classification by the size of granularity;
It is 8, total mixed that to make powder all be to be undertaken by traditional handicraft.
The 5th kind of preparation method:
1, the evaluation of Chinese crude drug or herbal mixture is the true and false and the quality in order to confirm Chinese crude drug or herbal mixture;
2, the process of preparing Chinese medicine is to concoct by the concocting method of traditional Chinese crude drug;
3, drying is that Chinese crude drug or herbal mixture after concocting are carried out drying;
4, supercritical fluid extraction is by medium-CO
2Or noble gas extracts, and obtains granularity greater than 1 micron and less than 75 microns Chinese medicine micron extract or herbal mixture micron extract;
5, drying;
6, classification is that above-mentioned Chinese medicine micron extract or herbal mixture micron extract are carried out classification by the size of granularity;
It is 7, total mixed that to make powder all be to be undertaken by traditional handicraft.
Embodiment 1
The preparation method of the instant Radix Isatidis powder of micron
1, identifies the true and false and the quality of Radix Isatidis; Get Radix Isatidis 500g;
2, concoct;
3, drying;
4, pulverize with pulverizer, make its granularity between 76 microns～800 microns;
5, adopt ball mill pulverizing, Radix Isatidis powder is broken into granularity greater than 1 micron and less than 75 microns ultramicro powder;
6, drying;
7, carry out classification by the size of granularity;
8, always mix with traditional method, make a micron Radix Isatidis powder.
Embodiment 2
The preparation method of micron Xuanmai Ganju powder
1, identifies the true and false and the quality of Radix Scrophulariae, Radix Ophiopogonis, Radix Platycodonis, Radix Glycyrrhizae; Get Radix Scrophulariae 400g, Radix Ophiopogonis 400g, Radix Platycodonis 400g, Radix Glycyrrhizae 400g;
2, concoct;
3, drying;
4, adding the 8000g hydromining extracts with infusion process;
5, being condensed into relative density is 1.32～1.35 thick paste, drying;
6, adopt Ultrasonic Pulverization, extract is ground into granularity greater than 1 micron and less than 75 microns extract;
7, drying;
8, carry out classification by the size of granularity;
9, always mix with traditional method, make a micron Xuanmai Ganju powder.
Embodiment 3
The preparation method of micron seven ingredient beard beautifying powder
1, identifies the true and false and the quality and the process of preparing Chinese medicine of Radix Polygoni Multiflori, Radix Angelicae Sinensis, Fructus Psoraleae, Fructus Lycii, Semen Cuscutae, Poria, Radix Achyranthis Bidentatae; Get Radix Polygoni Multiflori 640g, Radix Angelicae Sinensis 160g, Fructus Psoraleae (stir-fry) 160g, Fructus Lycii 160g, Semen Cuscutae (stir-fry) 160g, Poria 160g, Radix Achyranthis Bidentatae 160g;
2, drying;
3, adding 8000g ethanol adopts circumfluence method to extract;
4, be condensed into clear paste or thick paste, relative density is 1.2-1.6, drying;
5, adopt the method for comminution by gas stream, extract is ground into granularity greater than 1 micron and less than 75 microns extract;
6, drying;
7, carry out classification by the size of granularity;
8, always mix with traditional method, make a micron seven ingredient beard beautifying powder.
Embodiment 4
The preparation method of the sub-powder of micron XIANGSHALIUJUNZI
1, identifies the true and false and the quality and the process of preparing Chinese medicine of the Radix Aucklandiae, Fructus Amomi, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Glycyrrhizae, Pericarpium Citri Reticulatae, the Rhizoma Pinelliae; Get Radix Aucklandiae 70g, Fructus Amomi 80g, Radix Codonopsis 100g, the Rhizoma Atractylodis Macrocephalae (stir-fry) 200g, Poria 200g, Radix Glycyrrhizae (processing) 70g, Pericarpium Citri Reticulatae 80g, Rhizoma Pinelliae (processed) 100g;
2, drying;
3, above-mentioned herbal mixture is ground into 76 microns～800 microns granule with pulverizer;
4, adding 6000g ethanol adopts percolation to extract;
5, be condensed into clear paste or thick paste, relative density is 1.2-1.6, drying;
6, adopt the method for vibrant pulverization, extract is ground into granularity greater than 1 micron and less than 75 microns extract;
7, drying;
8, carry out classification by the size of granularity;
9, always mix with traditional method, make the sub-powder of micron XIANGSHALIUJUNZI.
Embodiment 5
The preparation method of micron six drugs containing rehmanniae powder
1, identifies the true and false and the quality and the process of preparing Chinese medicine of Radix Rehmanniae Preparata, Fructus Corni, Cortex Moutan, Rhizoma Dioscoreae, Poria, Rhizoma Alismatis; Get Radix Rehmanniae Preparata 160g, Fructus Corni (system) 80g, Cortex Moutan 60g, Rhizoma Dioscoreae 80g, Poria 60g, Rhizoma Alismatis 60g;
2, drying;
3, above-mentioned herbal mixture is ground into 76 microns～800 microns granule with pulverizer;
4, with CO
2Make medium,, obtain granularity greater than 1 micron and less than 75 microns extract with supercritical fluid extraction extraction;
5, drying;
6, carry out classification by the size of granularity;
7, always mix with traditional method, make a micron six drugs containing rehmanniae powder.
Embodiment 6
The preparation method of micron invigorating the spleen and replenishing QI powder
1, identifies the true and false and the quality and the process of preparing Chinese medicine of the Radix Astragali, Radix Codonopsis, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Cimicifugae, Radix Bupleuri, Pericarpium Citri Reticulatae; Get the Radix Astragali (processing) 200g, Radix Codonopsis 60g, Radix Glycyrrhizae (processing) 100g, the Rhizoma Atractylodis Macrocephalae (stir-fry) 60g, Radix Angelicae Sinensis 60g, Rhizoma Cimicifugae 60g, Radix Bupleuri 60g, Pericarpium Citri Reticulatae 60g;
2, drying;
3, with CO
2Make medium,, obtain granularity greater than 1 micron and less than 75 microns extract with supercritical fluid extraction extraction;
4, drying;
5, carry out classification by the size of granularity;
6, always mix with traditional method, make a micron invigorating the spleen and replenishing QI powder.
Embodiment 7
The preparation method of micron WULING SAN agent
1, identifies the true and false and the quality and the process of preparing Chinese medicine of Poria, Rhizoma Alismatis, Polyporus, Cortex Cinnamomi, the Rhizoma Atractylodis Macrocephalae; Get Poria 60g, Rhizoma Alismatis 300g, Polyporus 180g, Cortex Cinnamomi 120g, the Rhizoma Atractylodis Macrocephalae (stir-fry) 180g;
2, drying;
3, with pulverizer above-mentioned herbal mixture is pulverized, made its granularity between 76 microns～800 microns;
4, the water that adds 8400g adopts infusion process to extract;
5, be condensed into clear paste or thick paste, relative density is 1.2-1.6, drying;
6, adopt the method for ball mill pulverizing and centrifugal pulverizing, extract is ground into granularity greater than 1 micron and less than 75 microns extract;
7, drying;
8, carry out classification by the size of granularity;
9, always mix with traditional method, make a micron WULING SAN agent.
Embodiment 8
Micron is returned the preparation method of spleen powder
1, identifies the true and false and the quality and the process of preparing Chinese medicine of Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Radix Glycyrrhizae, Poria, Radix Polygalae, Semen Ziziphi Spinosae, Arillus Longan, Radix Angelicae Sinensis, the Radix Aucklandiae, Fructus Jujubae; Get Radix Codonopsis 80g, the Rhizoma Atractylodis Macrocephalae (stir-fry) 160g, the Radix Astragali (processing) 80g, Radix Glycyrrhizae (processing) 40g, Poria 160g, Radix Polygalae (system) 160g, Semen Ziziphi Spinosae (stir-fry) 80g, Arillus Longan 160g, Radix Angelicae Sinensis 160g, Radix Aucklandiae 40g, Fructus Jujubae (enucleation) 40g;
2, drying;
3, with pulverizer above-mentioned herbal mixture is pulverized, made its granularity between 76 microns～800 microns;
4, the water that adds 6000g adopts circumfluence method to extract;
5, be condensed into clear paste or thick paste, relative density is 1.2-1.6, drying;
6, adopt to stir pulverize the method that gentle stream is pulverized, extract is ground into granularity greater than 1 micron and less than 75 microns extract;
7, drying;
8, carry out classification by the size of granularity;
9, always mix with traditional method, make micron and return spleen powder.
Embodiment 9
The preparation method of the instant SHENGMAI SAN agent of micron
1, identifies the true and false and the quality of Radix Ginseng, winter wheat, Fructus Schisandrae Chinensis; Get Radix Ginseng 100g, winter wheat 200g, Fructus Schisandrae Chinensis 100g;
2, concoct;
3, drying;
4, pulverize with pulverizer, make its granularity between 76 microns～800 microns;
5, adopt the method for vibrant pulverization, Radix Ginseng, winter wheat, Fructus Schisandrae Chinensis powder are broken into granularity greater than 1 micron and less than 75 microns ultramicro powder;
6, drying;
7, carry out classification by the size of granularity;
8, always mix with traditional method, make the instant SHENGMAI SAN agent of micron.
Embodiment 10
The preparation method of micron five tastes Fructus Hippophae powder
1, identify that Fructus Hippophae height, the Radix Aucklandiae, Fructus Vins are done, the true and false and the quality of Radix Glycyrrhizae, Fructus Gardeniae; Get the high 180g of Fructus Hippophae, Radix Aucklandiae 150g, Fructus Vins dried 120g, Radix Glycyrrhizae 90g, Fructus Gardeniae 60g;
2, concoct;
3, drying;
4, the ethanol that adds 1800g adopts circumfluence method to extract;
5, being condensed into relative density is 1.20～1.50 clear paste, drying;
6, adopt the method for comminution by gas stream, extract is ground into granularity greater than 1 micron and less than 75 microns extract;
7, drying;
8, carry out classification by the size of granularity;
9, always mix with traditional method, make a micron five tastes Fructus Hippophae powder.
Embodiment 11
The preparation method of micron Radix Notoginseng powder
1, identifies the true and false and the quality of Radix Notoginseng; Get Radix Notoginseng 1000g;
2, concoct;
3, drying;
4, above-mentioned herbal mixture is ground into 76 microns～800 microns granule with pulverizer;
5, adopt the method for ball mill pulverizing, extract is ground into granularity greater than 1 micron and less than 75 microns granule;
6, drying;
7, carry out classification by the size of granularity;
8, always mix with traditional method, make a micron Radix Notoginseng powder.
Claims (6)
1, a kind of micron Chinese medicine powder is the Chinese powder medicine of being made by Chinese crude drug or Chinese medicine extract, it is characterized in that, micron Chinese medicine powder is to make with micron Chinese medicine or micron herbal mixture or Chinese medicine micron extract or herbal mixture micron extract.
2, a kind of preparation method that realizes the described micron Chinese medicine powder of claim 1 is characterized in that, this preparation method follows these steps to order and carries out:
A, medical material or herbal mixture evaluation, the process of preparing Chinese medicine, drying;
B, pulverize with pulverizer, making its granularity is 76 microns to 800 microns;
C, with comminution by gas stream, ball mill pulverizing, vibrant pulverization, Ultrasonic Pulverization, stirring pulverize, one of them breaking method or the wherein combination of two kinds of breaking methods of centrifugal pulverizing, make granularity greater than 1 micron and less than 75 microns granule;
D, drying;
E, carry out classification by the size of granularity;
F, always mixed with traditional method makes micron Chinese medicine powder.
3, a kind of preparation method that realizes the described micron Chinese medicine powder of claim 1 is characterized in that, this preparation method follows these steps to order and carries out:
The evaluation of a, Chinese crude drug or herbal mixture, the process of preparing Chinese medicine, drying;
B, pulverize with pulverizer, making its granularity is 76 microns to 800 microns;
C, add the solvent-water or the ethanol of 4～10 times of its weight;
D, employing infusion process or percolation or circumfluence method or extraction extract effective substance;
E, drying;
F, with comminution by gas stream, ball mill pulverizing, vibrant pulverization, Ultrasonic Pulverization, stirring pulverize, one of them breaking method or the wherein combination of two kinds of breaking methods of centrifugal pulverizing, make granularity greater than 1 micron and less than 75 microns granule;
G, drying;
H, carry out classification by the size of granularity;
I. always mix with traditional method, make micron Chinese medicine powder.
4, a kind of preparation method that realizes the described micron Chinese medicine powder of claim 1 is characterized in that, this preparation method follows these steps to order and carries out:
The evaluation of a, Chinese crude drug or herbal mixture, the process of preparing Chinese medicine, drying;
B, add the solvent-water or the ethanol of 4～10 times of its weight;
C, employing infusion process or percolation or circumfluence method or extraction extract effective substance;
D, drying;
E, with comminution by gas stream, ball mill pulverizing, vibrant pulverization, Ultrasonic Pulverization, stirring pulverize, one of them breaking method or the wherein combination of two kinds of breaking methods of centrifugal pulverizing, make granularity greater than 1 micron and less than 75 microns granule;
E, drying;
F, carry out classification by the size of granularity;
G, always mixed with traditional method makes micron Chinese medicine powder.
5, a kind of preparation method that realizes the described micron Chinese medicine powder of claim 1 is characterized in that, this preparation method follows these steps to order and carries out:
The evaluation of a, Chinese crude drug or herbal mixture, the process of preparing Chinese medicine, drying;
B, pulverize with pulverizer, making its granularity is 76 microns to 800 microns;
C, by medium-CO
2Or noble gas carries out supercritical fluid extraction, obtains granularity greater than 1 micron and less than 75 microns Chinese medicine micron extract or herbal mixture micron extract;
D, drying;
E, carry out classification by the size of granularity;
F, always mixed with traditional method makes micron Chinese medicine powder.
6, a kind of preparation method that realizes the described micron Chinese medicine powder of claim 1 is characterized in that, this preparation method follows these steps to order and carries out:
The evaluation of a, Chinese crude drug or herbal mixture, the process of preparing Chinese medicine, drying;
B, by medium-CO
2Or noble gas carries out supercritical fluid extraction, obtains granularity greater than 1 micron and less than 75 microns Chinese medicine micron extract or herbal mixture micron extract;
C, drying;
D, carry out classification by the size of granularity;
E, always mixed with traditional method makes micron Chinese medicine powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01106567 CN1375282A (en) | 2001-03-21 | 2001-03-21 | Micron level Chinese medicine powder and its prepn. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01106567 CN1375282A (en) | 2001-03-21 | 2001-03-21 | Micron level Chinese medicine powder and its prepn. |
Publications (1)
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463203A (en) * | 2013-09-18 | 2013-12-25 | 四川泷海洋动物药业有限公司 | Honeysuckle-scutellaria baicalensis-forsythia superfine powder and production method thereof |
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2001
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463203A (en) * | 2013-09-18 | 2013-12-25 | 四川泷海洋动物药业有限公司 | Honeysuckle-scutellaria baicalensis-forsythia superfine powder and production method thereof |
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