CN103918900A - Low-carbon feed additive capable of replacing antibiotics - Google Patents
Low-carbon feed additive capable of replacing antibiotics Download PDFInfo
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- CN103918900A CN103918900A CN201410201586.8A CN201410201586A CN103918900A CN 103918900 A CN103918900 A CN 103918900A CN 201410201586 A CN201410201586 A CN 201410201586A CN 103918900 A CN103918900 A CN 103918900A
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- antibiotics
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- 229910052799 carbon Inorganic materials 0.000 title claims abstract description 25
- 239000003242 anti bacterial agent Substances 0.000 title claims abstract description 23
- 229940088710 antibiotic agent Drugs 0.000 title claims abstract description 23
- 239000003674 animal food additive Substances 0.000 title abstract 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 24
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 claims abstract description 16
- 108010011619 6-Phytase Proteins 0.000 claims abstract description 13
- 239000004382 Amylase Substances 0.000 claims abstract description 13
- 102000013142 Amylases Human genes 0.000 claims abstract description 13
- 108010065511 Amylases Proteins 0.000 claims abstract description 13
- 235000019418 amylase Nutrition 0.000 claims abstract description 13
- 229940085127 phytase Drugs 0.000 claims abstract description 13
- 239000000654 additive Substances 0.000 claims abstract description 12
- 230000000996 additive effect Effects 0.000 claims abstract description 12
- 239000005844 Thymol Substances 0.000 claims abstract description 8
- 229960000790 thymol Drugs 0.000 claims abstract description 8
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims abstract description 7
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims abstract description 7
- 235000005822 corn Nutrition 0.000 claims abstract description 7
- 101710121765 Endo-1,4-beta-xylanase Proteins 0.000 claims abstract description 6
- 235000013312 flour Nutrition 0.000 claims abstract description 6
- 230000000694 effects Effects 0.000 claims description 15
- WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 claims description 7
- WBYWAXJHAXSJNI-SREVYHEPSA-N Cinnamic acid Chemical compound OC(=O)\C=C/C1=CC=CC=C1 WBYWAXJHAXSJNI-SREVYHEPSA-N 0.000 claims description 7
- 229930016911 cinnamic acid Natural products 0.000 claims description 7
- 235000013985 cinnamic acid Nutrition 0.000 claims description 7
- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 claims description 7
- 241000209149 Zea Species 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 abstract description 9
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract description 6
- 240000008042 Zea mays Species 0.000 abstract description 5
- 241001465754 Metazoa Species 0.000 abstract description 4
- 229910052757 nitrogen Inorganic materials 0.000 abstract description 4
- 238000012545 processing Methods 0.000 abstract description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract description 3
- 235000019621 digestibility Nutrition 0.000 abstract description 3
- 241000282887 Suidae Species 0.000 abstract description 2
- 238000009395 breeding Methods 0.000 abstract description 2
- 230000001488 breeding effect Effects 0.000 abstract description 2
- KJPRLNWUNMBNBZ-QPJJXVBHSA-N (E)-cinnamaldehyde Chemical compound O=C\C=C\C1=CC=CC=C1 KJPRLNWUNMBNBZ-QPJJXVBHSA-N 0.000 abstract 1
- 241000282898 Sus scrofa Species 0.000 description 22
- 241001071864 Lethrinus laticaudis Species 0.000 description 12
- 230000002354 daily effect Effects 0.000 description 12
- 206010012735 Diarrhoea Diseases 0.000 description 8
- 230000003115 biocidal effect Effects 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- 235000014590 basal diet Nutrition 0.000 description 4
- 235000021050 feed intake Nutrition 0.000 description 4
- 230000037406 food intake Effects 0.000 description 4
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000003862 health status Effects 0.000 description 3
- 229910052698 phosphorus Inorganic materials 0.000 description 3
- 239000011574 phosphorus Substances 0.000 description 3
- 239000002689 soil Substances 0.000 description 3
- 206010059866 Drug resistance Diseases 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 240000007594 Oryza sativa Species 0.000 description 2
- 235000007164 Oryza sativa Nutrition 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 238000009360 aquaculture Methods 0.000 description 2
- 244000144974 aquaculture Species 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 229940088598 enzyme Drugs 0.000 description 2
- 238000013401 experimental design Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 235000009566 rice Nutrition 0.000 description 2
- 208000012153 swine disease Diseases 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 235000019750 Crude protein Nutrition 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 206010020843 Hyperthermia Diseases 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000036031 hyperthermia Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000001228 trophic effect Effects 0.000 description 1
- 235000015099 wheat brans Nutrition 0.000 description 1
Landscapes
- Feed For Specific Animals (AREA)
Abstract
The invention relates to the technical field of animal feed processing, and discloses a low-carbon feed additive capable of replacing antibiotics. The low-carbon feed additive comprises, by weight, 18.64% of corn flour, 70% of citric acid, 0.09% of thymol, 0.27% of cinnamyl aldehyde, 5% of xylanase, 5% of amylase and 1% of phytase. Generally, the appending proportion of the additive in feed is 1% to 2%, on the basis that pig production performance is guaranteed, the additive amount of the antibiotics in the feed can be greatly reduced, the antibiotics do not need to be added in the feed, and therefore the health level and the production performance of pigs can be guaranteed. Meanwhile, zymin for improving feed digestibility is added, and therefore the amount of carbon and nitrogen, discharged to the environment, of the breeding industry can be lowered.
Description
Technical field
The present invention relates to animal feed processing technique field, specifically a kind of low-carbon (LC) feed addictive of substitute antibiotics.
Background technology
China has been used a large amount of antibiotic in the process of raising pigs, cause swine disease to become increasingly complex, the treatment of swine disease is also more and more difficult, and new virus and virus variation situation often can occur in recent years, as the porcine hyperthermia in recent years occurring, high influenza and the streptococcosis etc. of causing a disease of H5N1; Simultaneously, some antibiotic are residual in animal body, harmful microbe drug resistance passes to the mankind by pig, for human diseases, treatment has also brought very large difficulty, therefore, need us to reduce as far as possible and in breeding production, use antibiotic, as far as possible by raising and the bioactivator substitute antibiotics of feeding and management, with this, reduce harmful microorganism to antibiotic drug resistance, in improving animal health level, the general level of the health that also greatly improves the mankind reduces the chance by synzoic communicable disease.
Summary of the invention
The present invention is directed to the problem of above-mentioned existence, a kind of low-carbon (LC) feed addictive of substitute antibiotics is provided.Ensureing, on the basis of pig production performance, can greatly to reduce antibiotic addition in feed, need in feed, not add antibiotic, just can ensure the general level of the health and the production performance of pig.Meanwhile, add the enzyme preparation that improves feed digestibility, can reduce the discharge capacity of aquaculture to environment carbon and nitrogen.
The present invention for achieving the above object, takes following technical scheme to be achieved:
A low-carbon (LC) feed addictive for substitute antibiotics, comprises the following component of mass percent: corn flour 18.64%, citric acid 70%, Thymol 0.09%, cinnamic acid 0.27%, zytase 5%, amylase 5% and phytase 1%.
Preferably, described corn flour 1864g, citric acid 7000g, Thymol 9g, cinnamic acid 27g, zytase 500g, amylase 500g, phytase 100g.
Preferably, described xylanase activity content is at least 4 × 10
5u/kg.
Preferably, described amylase activity content is at least 1 × 10
5u/kg.
Preferably, described phytase activity content is at least 5 × 10
4u/kg.
Preferably, the adding proportion of described additive in feed is 1%～2%.Feed addictive of the present invention can be added in any pig feed, is applicable to all pig feed kinds, comprises sow, piggy and large pig.
Compared with prior art, beneficial effect of the present invention is as follows: 1, substitute antibiotics, can ensure the general level of the health and the production performance of pig; 2, add the enzyme preparation that improves feed digestibility, can reduce the discharge capacity of aquaculture to environment carbon and nitrogen.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further illustrated.
Embodiment 1
A low-carbon (LC) feed addictive for substitute antibiotics, comprises the following component of mass percent: corn flour 18.64%, citric acid 70%, Thymol 0.09%, cinnamic acid 0.27%, zytase 5%, amylase 5% and phytase 1%.Wherein, xylanase activity content is at least 4 × 10
5u/kg, amylase activity content is at least 1 × 10
5u/kg, phytase activity content is at least 5 × 10
4u/kg.
The adding proportion of above-mentioned feed addictive in feed is 1%～2%.Add above-mentioned additive and possess following advantage: 1, improve the general level of the health of pig, can reduce the diarrhea rate of piggy stage pig, after the antibiotic interpolation substituting in feed, the diarrhea rate in piggy stage can reduce by 17%; 2, improve the feed efficiency of pig, reduce the discharge capacity of nutriment in ight soil.The discharge capacity that the discharge capacity of N in ight soil can reduce by 6%, C can reduce by 4%, and the discharge capacity of phosphorus can reduce 30%.
Embodiment 2
A low-carbon (LC) feed addictive for substitute antibiotics, is evenly mixed by following component: ground rice 1864g, citric acid 7000g, Thymol 9g, cinnamic acid 27g, zytase 500g, amylase 500g, phytase 100g.Wherein, xylanase activity content is 4 × 10
5u/kg, amylase activity content is 1 × 10
5u/kg, phytase activity content is 5 × 10
4u/kg.
In weanling pig feed, add the low-carbon (LC) feed addictive of above-mentioned substitute antibiotics, adding proportion is 1.5%, can improve the feed intake 12% of weanling pig, and feedstuff-meat ratio can decline 5%, can reduce diarrhea of weaned piglets rate 50% simultaneously.
In middle pig feed, add the low-carbon (LC) feed addictive of above-mentioned substitute antibiotics, adding proportion is 1%, can substitute the antibiotic interpolation in feed, the feed feed intake 5% of pig in raising, feedstuff-meat ratio can decline 3%, N discharge capacity in ight soil reduces by 6%, C discharge capacity and reduces by 4%, and the discharge capacity of phosphorus reduces 30%.
In farrowing sow and agent of feed for nursing sow, add the low-carbon (LC) feed addictive of above-mentioned substitute antibiotics, adding proportion is 1%, can improve the feed intake 12% of milking sow, and the weanling weight of piglet can improve 14%.
Embodiment 3
A low-carbon (LC) feed addictive for substitute antibiotics, is evenly mixed by following component: ground rice 1864g, citric acid 7000g, Thymol 9g, cinnamic acid 27g, zytase 500g, amylase 500g, phytase 100g.Wherein, xylanase activity content is 4 × 10
5u/kg, amylase activity content is 1 × 10
5u/kg, phytase activity content is 5 × 10
4u/kg.
Choose respectively the piggy stage 100 of (18-20kg) galts and the middle pig stage 100 of (50-55kg) galts, be divided at random control group (basal diet) and test group (the low-carbon (LC) feed addictive of basal diet+a kind of substitute antibiotics, hereinafter to be referred as additive) carry out the feeding experiment of 50 days, every group 5 processing (10 is 1 processing), experimental design is in table 1.
Table 1 experimental design
Basal diet is prepared in table 2:
The preparation of table 2 basal diet
| Raw material | Piggy daily ration composition | Middle swine rations composition |
| Corn | 66 | 66 |
| Dregs of beans | 25 | 21 |
| Wheat bran | 4 | 9 |
| Soya-bean oil | 1 | － |
| Premix | 4 | 4 |
| Trophic level | ? | ? |
| Digestible energy (MJ/kg) | 13.8 | 13.6 |
| Crude protein | 16.9 | 15.9 |
| Calcium | 0.8 | 0.7 |
| Total phosphorus | 0.6 | 0.5 |
| Lysine | 0.8 | 0.65 |
| Egg+Guang | 0.45 | 0.4 |
Take initial body weight and final body weight, calculate daily gain, statistics feed intake, calculates feedstuff-meat ratio.Carry out disease, diagnosis and treatment medication and death condition record every day, record diarrhea rate and the death rate.Additive of the present invention on the impact of piggy stage and middle pig stage production performance in table 3, table 4, additive of the present invention on the impact of piggy stage health status in table 5.
The impact of table 3 additive of the present invention on piggy rank production performance
| ? | Control group | Test group | With control group comparison |
| Minimum weight, kg | 19.2 | 19.5 | ? |
| Finish weight, kg | 49.5 | 52.0 | ? |
| Daily gain, g | 606 | 650 | 7％ |
| Daily ingestion amount, g | 1638 | 1688 | 3％ |
| Feedstuff-meat ratio | 2.70 | 2.6 | 4％ |
In the piggy stage, compared with control group, test group daily ingestion amount improves 3%, and daily gain improves 7%, and feedstuff-meat ratio declines 4%.
The impact of table 4 additive centering pig stage of the present invention production performance
| ? | Control group | Test group | With control group comparison |
| Minimum weight, kg | 50.9 | 50.9 | ? |
| Finish weight, kg | 88.5 | 90.4 | ? |
| Daily gain, g | 752 | 790 | 5％ |
| Daily ingestion amount, g | 2368 | 2420 | 2％ |
| Feedstuff-meat ratio | 3.15 | 3.06 | 3％ |
In the middle pig stage, compared with control group, test group daily ingestion amount improves 2%, and daily gain improves 5%, and feedstuff-meat ratio declines 3%.
The impact of table 5 additive of the present invention on piggy stage health status
| ? | The head number of days of all suffering from diarrhoea |
| Control group | 3.0 |
| Test group | 2.5 |
| Improve % | 17％ |
In the piggy stage, the average diarrhoea number of days of control group pig is 3.0 days, and the head number of days of all suffering from diarrhoea of test group is 2.5 days, and diarrhea rate declines 17%, and the health status of test pig is significantly better than control group.
The above results shows, compared with control group, adds additive of the present invention in feed, and the daily gain in piggy stage improves, and feedstuff-meat ratio reduces; In large pig stage daily gain improve, feedstuff-meat ratio improves.
Only as described above, it is only the present invention's preferred embodiment, when not limiting with this scope of the present invention, the content of generally recording according to the claims in the present invention and description has been done simple equivalence and has been changed and modify, and is all still covered by the claims of the invention.In addition, summary part and title are only the use for auxiliary patent document search, are not used for limiting the present invention's interest field.
Claims (6)
1. the low-carbon (LC) feed addictive of a substitute antibiotics, it is characterized in that, comprise the following component of mass percent: corn flour 18.64%, citric acid 70%, Thymol 0.09%, cinnamic acid 0.27%, zytase 5%, amylase 5% and phytase 1%.
2. the low-carbon (LC) feed addictive of a kind of substitute antibiotics according to claim 1, is characterized in that, described corn flour 1864g, citric acid 7000g, Thymol 9g, cinnamic acid 27g, zytase 500g, amylase 500g, phytase 100g.
3. the low-carbon (LC) feed addictive of a kind of substitute antibiotics according to claim 1, is characterized in that, described xylanase activity content is at least 4 × 10
5u/kg.
4. the low-carbon (LC) feed addictive of a kind of substitute antibiotics according to claim 1, is characterized in that, described amylase activity content is at least 1 × 10
5u/kg.
5. the low-carbon (LC) feed addictive of a kind of substitute antibiotics according to claim 1, is characterized in that, described phytase activity content is at least 5 × 10
4u/kg.
6. according to the low-carbon (LC) feed addictive of a kind of substitute antibiotics described in any one in claim 1 to 5, it is characterized in that, the adding proportion of described additive in feed is 1%～2%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410201586.8A CN103918900A (en) | 2014-05-13 | 2014-05-13 | Low-carbon feed additive capable of replacing antibiotics |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410201586.8A CN103918900A (en) | 2014-05-13 | 2014-05-13 | Low-carbon feed additive capable of replacing antibiotics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103918900A true CN103918900A (en) | 2014-07-16 |
Family
ID=51137484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410201586.8A Pending CN103918900A (en) | 2014-05-13 | 2014-05-13 | Low-carbon feed additive capable of replacing antibiotics |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103918900A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104171439A (en) * | 2014-07-17 | 2014-12-03 | 桐城市永锦建筑工程有限公司 | Feed additive |
| CN105076717A (en) * | 2015-07-14 | 2015-11-25 | 上海美农生物科技股份有限公司 | Formula and processing method of feed additive for improving production performance of animals and guaranteeing health of alimentary canals |
| CN107125472A (en) * | 2017-05-27 | 2017-09-05 | 曹江山 | A kind of agent of feed for pregnancy sow additive and preparation method |
| CN110024905A (en) * | 2019-05-22 | 2019-07-19 | 河南聚推牧业有限公司 | A kind of enterococcus faecalis feed addictive |
| CN111011634A (en) * | 2019-12-31 | 2020-04-17 | 广东汇海农牧科技集团有限公司 | Pig feed additive for preventing diarrhea of weaned piglets and pig feed |
| CN111328928A (en) * | 2020-03-24 | 2020-06-26 | 广东汇海农牧科技集团有限公司 | Antibiotic substitute feed additive |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104171439A (en) * | 2014-07-17 | 2014-12-03 | 桐城市永锦建筑工程有限公司 | Feed additive |
| CN105076717A (en) * | 2015-07-14 | 2015-11-25 | 上海美农生物科技股份有限公司 | Formula and processing method of feed additive for improving production performance of animals and guaranteeing health of alimentary canals |
| CN105076717B (en) * | 2015-07-14 | 2019-09-24 | 上海美农生物科技股份有限公司 | For improving breeding performonce fo animals and guaranteeing the feed addictive prescription and processing method of alimentary canal health |
| CN107125472A (en) * | 2017-05-27 | 2017-09-05 | 曹江山 | A kind of agent of feed for pregnancy sow additive and preparation method |
| CN110024905A (en) * | 2019-05-22 | 2019-07-19 | 河南聚推牧业有限公司 | A kind of enterococcus faecalis feed addictive |
| CN111011634A (en) * | 2019-12-31 | 2020-04-17 | 广东汇海农牧科技集团有限公司 | Pig feed additive for preventing diarrhea of weaned piglets and pig feed |
| CN111328928A (en) * | 2020-03-24 | 2020-06-26 | 广东汇海农牧科技集团有限公司 | Antibiotic substitute feed additive |
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| CB02 | Change of applicant information |
Address after: 529165 Guangdong city of Jiangmen province Hetang Tagang west two Road Development Zone No. 5 West Applicant after: JIANGMEN HUIHAI AGRICULTURAL AND ANIMAL HUSBANDRY SCIENCE AND TECHNOLOGY GROUP CO., LTD. Address before: 529000 Guangdong city of Jiangmen province Hetang Tagang Sai two Road West Development Zone No. 5 Applicant before: Jiangmen Huihai Feed Factory Co., Ltd. |
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Application publication date: 20140716 |