CN104906203A - Tinea manus and pedis treatment painless nano emulsifiable paste - Google Patents

Abstract

The invention discloses a painless nano cream for treating tinea manus and pedis, which belongs to the technical field of production and preparation of small daily chemical products cream for treating tinea manus and pedis. Nanoparticles are made of natural animal and plant mineral elements such as snake oil rhubarb, marmot oil centipede, musk mido, snake skin pine and cypress leaves, cicada slough propolis, mylabris medical stone, snake gall cream white ringworm skin, and are made of nano particles through modern high-tech nanotechnology The diameter scale is in the range of 0.1-5μm, and it has a huge surface area, which can directly introduce drug nanoparticles into the cells containing lesions, and directly act on cellular pathogens through lysosome uptake to achieve the effect of controlling, killing, and treating infection. Safe, long-lasting, efficient, broad-spectrum, antibacterial, sterilizing, destroys the structure of the bacterial membrane to completely degrade the bacteria, and prevents secondary infections caused by endotoxins. It is a painless nano-cream for the treatment of tinea pedis.

Description

Painless nano cream for tinea manus and pedis

technical field

The invention discloses a painless nano cream for treating tinea manus and pedis, and belongs to the technical field of production and preparation of small daily chemical products painless cream for treating tinea manus and pedis.

Background technique

Tinea manus and pedis refers to superficial fungal infection of fingers (toes) and palms and plantar surface skin. The pathogens are mostly Trichophyton rubrum, Epidermophyton flocculus and Trichophyton mentagrophytes. Most of them are indirect infections, such as using public baths and slippers. Clinically, it can be divided into blister type, scaly keratosis type, and maceration type. At the beginning, large blisters are seen in groups or scattered on needles, which are not easy to rupture. After drying, the epidermis of the blister top falls off and forms ring-shaped scales. New lesions appear one after another and merge with each other to form multiple rings, which is the blister type. The main manifestations are desquamation, thickened keratin, and rough and dry skin, which is the scaly keratosis type. Fingers (toes) are impregnated and whitish with mesothelin, often caused by severe itching, scratching and rubbing of the epidermis, exposing the flushed and rotten surface, etc., which is the impregnated type.

Western medicine often adopts corresponding external treatment methods for different clinical types, and the internal medicine mainly includes ketoconazole and the like. Tinea pedis is known as "swan palm wind" in traditional Chinese medicine, and tinea pedis is called "dampness of the feet". Control with heat-clearing and damp-damp detoxification, combine internally and externally.

Contents of the invention

The object of the present invention is to provide a kind of painless nano cream for treating tinea manus and pedis.

Technical solution of the present invention is:

1, a kind of painless nano-emulsion for treating tinea manus and pedis, is characterized in that: it is composed of snake oil rhubarb natural animal and plant mineral element nano-emulsion according to the following mass proportioning %

Preparation:

① Screen and weigh the above raw materials;

② Grind 7 kinds of solid drugs such as Danyu, calcined oyster, dried alum, calcined gypsum, borneol, camphor, and water keel to very fine nanoemulsions, and mix them with salicylic acid powder, talcum powder, and titanium dioxide. Stir to mix well;

③ Add snake oil or glycerin to the material ②, stir and mix thoroughly to form a thick paste;

④Put rhubarb, flavescens, cnidium, Kochia chinensis, chuandongzi, and licorice into the pot, add water to cook, continue for 20-30 minutes after boiling, and filter to prepare the thinning syrup.

⑤ Dilute the thick paste ③ with the cooled thinning potion ④ until it becomes a paste, then pack it into a bag and seal it to get the finished product.

This product has the effects of chasing wind and dampness, clearing heat and detoxification, sterilizing and reducing inflammation, promoting blood circulation and promoting muscle growth. It is not only suitable for patients with athlete's foot (tinea pedis), but also for the treatment of tinea manuum, tinea corporis, jock itch, and tinea versicolor.

How to use: Wash your feet first, apply the ointment evenly on the affected area with a cotton pad, 2-3 times a day until it is cured.

This product has quick effect, good effect, stable long-term curative effect, not easy to relapse; no toxic side effects and adverse reactions, no scar after healing, safe and reliable.

2. A painless nano-emulsion for treating tinea manus and pedis, characterized in that it is composed of marmot oil centipede natural animal and plant mineral element nano-emulsion according to the following mass proportioning %

Preparation:

The preparation method of marmot oil is as follows: after the captured live marmot is killed, the material is taken for plague bacteriological experiment, and if the test is negative, the skin is extracted and the oil is refined into liquid oil, and after cooling, the water and residue are removed with a centrifuge or separator.

Soak angelica and comfrey in marmot oil for 24 hours, then boil the medicine and marmot oil together until the medicine is scorched, filter the marmot oil with a cloth, remove the medicine residue and keep the marmot oil, and finally boil the marmot oil again, The wax is melted, poured into a container, added centipede powder, vaseline, and borneol and fully mixed to obtain the nano ringworm ointment for treating tinea manus, pedis and foot odor.

This product has the functions of invigorating blood, cooling blood, moistening dryness, and promoting muscle growth. The process is simple, the raw materials are easy to obtain, and animal and plant resources are fully utilized. The skin is fine and smooth. 3. A painless nano-emulsion for treating tinea manus and pedis, characterized in that it is composed of the natural animal and plant mineral element nano-emulsion of musk and amitabha, and is composed of the following mass ratios: %

Preparation:

①Dissolve borneol with ethanol;

②Grind frankincense and peppermint and liquefy them;

③ Grind alum, sulfur, realgar, metha, keel, calamine, and light powder respectively, and then make nanoemulsion and mix evenly;

④ heat-fry the rhubarb and extract the concentrated solution to develop a nanoemulsion;

⑤ adding musk and aspirin to dimethyl sulfoxide and grinding them into nanoemulsions;

⑥Put the material obtained in the above steps into a blender, heat at 75-80°C and stir evenly, then add Vaseline, continue stirring evenly and cool down before bottling;

This product has the effects of anti-inflammatory and analgesic, bactericidal and antibacterial, expelling wind and dehumidification, removing putrefaction and promoting muscle growth, drying dampness and detoxification, killing insects and relieving itching, and nourishing the skin. It is mainly used to treat athlete's foot and tinea pedis; Just the affected area. This product is simple in process, reasonable in formula, convenient in use, quick in effect, remarkable in lasting effect, and has no toxic and side effects on human body.

4. A painless nano-emulsion for treating tinea manus and pedis, characterized in that it is composed of natural animal and plant mineral element nano-emulsion of snake bark pine and cypress leaves, and is composed of the following mass ratios: %

Preparation:

Use an aluminum container (do not use iron or copper) to heat the sesame oil until it boils, then remove from the heat, first add Zhang Dan, stir evenly, then add medicines except borneol one by one, stir while adding, until the medicine is evenly stirred into a nano-emulsion ointment, Finally, add borneol, stir until the medicine becomes cool, and store in separate packages.

This product has the effects of detoxifying sores, draining pus and promoting muscle regeneration. It is mainly used to treat various intractable skin diseases and various skin inflammation abscesses, hot boils, furuncles, beriberi and mild burns caused by mites.

When in use, just apply this product to the affected area. If the wound is ulcerated, wash the wound with warm water or light salt water, and apply the drug to the affected area, once in the morning and at night. After the beriberi is cured, it will no longer recur.

Impetigo, furuncle and athlete's foot are caused by bacteria or fungi. During the treatment process, the skin and towels and other utensils should be kept clean and disinfected, and irritating food should not be eaten.

This product is simple in process, reasonable in formula, convenient in use, quick in effect, remarkable in lasting effect, and has no toxic and side effects on human body.

5. A painless nano-emulsion for treating tinea manus and pedis, characterized in that it consists of cicada slough propolis natural animal and plant mineral element nano-emulsion, which is composed of the following mass ratios: %

Preparation:

①Crush the propolis to 40-60 mesh first, then put it together with Sophora flavescens, cicada slough, and hibiscus bark into 95% ethanol to soak and seal; then stir once a day, and filter out the liquid medicine after 7 days; then add royal jelly , peppermint oil, APC tablets (grinding powder), realgar powder, sulfur powder, coptis powder, sealwort powder, talc powder, blood dried powder, pearl powder, and the medicines are mixed together and ground into nano powder by nanotechnology, and then mixed with snake oil Cream is mixed and stirred evenly;

②Method: Mix the above prescriptions thoroughly and put them into a sterilized porcelain bottle for later use. During the treatment, wash the affected area with warm boiled water first, then apply ointment, rub your hands against each other, and feel hot until the oil stains are not visible on the wound surface. Once a day, a week is a course of treatment;

Propolis contains flavonoids, biologically active organic compounds and various elements, which can effectively sterilize and inhibit bacteria; royal jelly contains various hormones, especially 10-hydroxy-2-decenoic acid; Insect and nourish the skin; hibiscus bark has the effect of clearing heat, killing insects, and relieving itching; cicada slough has the effect of dispersing wind heat and removing itching; peppermint oil has good analgesic effect; snake oil cream is produced by Nantong Snake Therapy Research Institute The Chengjinxue brand snake oil cream has good anti-cracking, sterilizing, and skin-care effects; it has strong penetrating power, large specific surface area, high drug efficacy, and strong healing power.

This product has strong antipruritic and sterilizing effects, detoxification and dehumidification, anti-inflammatory and muscle-generating effects. It is suitable for treating various beriberi and maintaining the skin at the same time.

How to use: Wash and dry the affected area first, then apply this product on the affected area, once in the morning and once in the evening, and it can be cured by continuous use for 3-5 days.

This product is simple in process, reasonable in formula, convenient in use, quick in effect, remarkable in lasting effect, and has no toxic and side effects on human body.

6. A painless nano-emulsion for treating tinea manus and pedis, characterized in that it is composed of natural animal and plant mineral element nano-emulsion from Mylabris medical stone, which is composed of the following mass ratios: %

Preparation method:

The ultra-fine powder of nano small molecules made by the high-tech nanotechnology processing device used by Shangyao, except for the yellow wax, is first fried in sesame oil and slightly rolled, then fried with yellow wax, until there is no yellow foam, take it off the fire. Add the powdered medicine gradually and mix thoroughly to form a paste. Rubbing the affected area, or heating and drying therapy, the curative effect is better. This product detoxifies, kills insects and relieves itching, and is suitable for typhoid and tinea manuum. Due to the use of nanotechnology to make ultra-fine nanoparticles with a particle size of 0.1-5 μm, the drug can directly enter the cells of pathogens and release them slowly, thereby enhancing the treatment of fungal and viral infections in cells.

7. A painless nano-emulsion for treating tinea manus and pedis, characterized in that it consists of natural animal and plant mineral element nano-emulsion of Snake Gall Cream White Moss Cortex, which is composed of the following mass ratios: %

Preparation:

Grind other medicines except snake bile cream into fine powder according to the above ratio, extract with conventional carbon dioxide extraction or 60% ethanol extraction, and the filtrate is evaporated by thin film, ethanol is recovered, and concentrated into 1:1 (that is, each milliliter Containing crude drug 1g), the liquid extract with a relative density of 1.03-1.05 is ready for use. When used, the liquid extract is vacuum-dried and finely mixed with other materials, and the mixed material is then crushed, emulsified, homogenized, and dispersed with a nano-sized ultra-fine micronization device to granulate it into nano-sized particles. Small molecules with a diameter of 1800-2200 mesh sieve, the central particle size is 0.1-5μm, because the absorption of drugs is often dominated by the dissolution rate of the drug at the absorption site, and reducing the particle size can increase the surface area exposed to the medium , and promote dissolution, thereby improving the absorption and utilization of the drug, increasing the efficacy and therapeutic effect. Then mix it with snake gall cream, stir evenly to form a paste-like nano-emulsion ointment, and bottle it to get the finished product. Nano fine powder with a particle size of 0.1-5μm is made into nanoemulsion by modern high technology. This method can be referred to for the preparation of nanoemulsions in the above-mentioned embodiments. In this product, salicylic acid, benzoic acid, light powder, dried blood, realgar, sulfur, dry alum, alum, yellow dan, white ringworm skin, impatiens, cinnabar, gall, white aconite, cnidium, hundred steps, etc. Fungi, molds, and other pathogenic bacteria have strong killing and inhibiting effects, as well as anti-inflammatory and analgesic dehumidification and softening effects; Promoting effect; has a moisturizing effect on the skin. Snake gall cream has strong antibacterial, acaricidal, anti-allergic, anti-cracking and freckle-removing effects on skin fungi and mites. It is a skin care patent special effect product produced by Nantong Snake Research Institute.

This product has the functions of antibacterial and anti-inflammatory, expelling wind and dehumidification, detoxification and detoxification, promoting muscle repair and inhibiting fungal infection, etc. It is mainly used to treat athlete's foot.

How to use: Wash your feet first, apply ointment evenly on the affected area with a cotton swab, 1-2 times a day. Mild disease usually takes 2-4 days to heal, and severe disease usually takes 5-10 days to heal.

This product has a scientific formula, rapid onset, short curative effect, ideal effect, high cure rate, and no recurrence; no toxic side effects and adverse reactions, no pain, safe, comfortable and convenient to use.

Tinea manus and pedis refers to (toe) and palm, plantar, back of hand and foot dorsal dermatophyte infectious skin disease. It is similar to "swan palm wind", "stinky snail" and "snail blister" in traditional Chinese medicine.

"Surgery Authentic" records: "The wind of goose palm is caused by the heat and dryness of the stomach meridian of Foot Yangming, and it is condensed by the cold outside, causing the skin to wither... At first, there are purple spots and white spots, and the skin will become thick and cracked for a long time." For example, "Yizong Jinjian Surgical Heart Method" records: "This syndrome begins with purple and white spots, and white skin is folded, hard and thick, dry and cracked, and spreads all over the body." Another example is the record of stinky snails: "This syndrome is caused by damp-heat infusion of the kidney meridian. The feet are broken. The affliction is very small. The itching cannot be relieved by rubbing. When the skin is rotten and the smelly water flows, the itching will stop. The itching will continue the next day. Unhealed over the years, extremely lingering."

The cause of this disease is betting on dampness and heat, or it may be caused by poisoning and infection due to long-term residence in wetlands.

The disease is usually vesicular at the beginning, appearing in groups or scattered, desquamation occurs after ulceration or absorption, and merges with each other. Repeated attacks can cause thick skin, hyperkeratosis, dryness, roughness, desquamation, and chapping to form desquamation. Crumb type. If it occurs between the fingers (toes), the epidermis is impregnated and whitish, with exudate. If the epidermis is removed, a red wound surface is exposed, accompanied by severe pain, unbearable itching, and a special odor. Treatment should be heat-clearing and damp-damp detoxification and external application of ointment treatment, but the recurrence rate is high. The present invention uses the latest high-tech nanotechnology on the basis of traditional Chinese and western medicine treatment, and selects natural animal and plant mineral elements to develop a painless nano cream for treating tinea manus and pedis.

These natural animal and plant mineral elements are obtained by microemulsion polymerization. The size of the nanoparticles is in the range of 0.1-5 μm. Enzyme intake directly acts on pathogens in cells to achieve the functions of control, killing, treatment and infection. Nano-titanium dioxide TiO ₂ is a new type of inorganic photocatalytic fungicide. The material has low toxicity and is non-irritating to human skin. Strong antibacterial ability, wide antibacterial spectrum, instant bactericidal and antibacterial effect, long-lasting antibacterial effect, zinc oxide whisker ZnOw is a multi-component nano-composite antibacterial bactericide, which is a safe, durable, efficient, broad-spectrum, antibacterial, and bactericidal material. Nano-titanium dioxide has the characteristics of broad antibacterial spectrum, strong antibacterial power and low cost. When this kind of high-safety nano-titanium dioxide is sterilized, it relies on separating electron-hole pairs to activate surface adsorption substances to produce strong oxidizing agents and strong reducing agents. , attack bacterial organisms, play a bactericidal effect. Commonly used bactericides such as silver and copper can inactivate bacterial cells, but after the bacteria are killed, harmful components can be released, such as endotoxins. Nano-titanium dioxide can not only affect bacterial reproduction, but also attack the outer layer of bacterial cells, penetrate the cell membrane, destroy the bacterial cell membrane structure, achieve the purpose of completely degrading bacteria, and further prevent secondary pollution caused by endotoxins.

Tinea manuum and tinea pedis are tinea manuum and tinea pedis, which refer to superficial fungal infections of fingers (toes) and palms and plantar surface skin. The disease is mostly indirect infection, such as using public baths and slippers. In traditional Chinese medicine, tinea manuum is called "swan's palm", and tinea pedis is called "dampness of the feet", commonly known as "Hong Kong's foot". Humid environment or wearing airtight footwear for a long time are prone to disease.

Commonly seen on the soles of the feet and the edges of the feet, there are clusters or scattered small blisters, accompanied by itching. The damage can spread to all sides, and small blisters can merge into large blisters. Pustules can be seen after secondary infection of the blisters. It is caused by excessive sweating on the feet, dampness between the toes, and airtightness. The dipping between the toes is whitish, the base is flushed, there may be erosion and exudation, and a foul smell.

Previous treatment methods: generally use lotion, soaking agent, powder, tincture, alcohol preparation, ointment, etc., the treatment time is long and painful, itching cannot be relieved quickly, and it is easy to relapse. The cream of the present invention is added with medical stone nano-powder because it has a miraculous effect of cleansing water, and has the effect of sterilizing, purifying, and antagonizing the water droplets of wet toes sealed between shoes and socks, releasing trace elements, enhancing immunity, Improve the anti-infection ability, make the water between the wet and bacteria-carrying toes into clean pure water, purify, activate, and mineralize the living water, make the toes moist, and absorb chlorine, heavy metals, bacteria, viruses and bacteria in the water, Decomposition and inhibition can eliminate the strange smell caused by bacterial infection and prevent recurrence, which is helpful for the treatment and nursing of tinea manus and pedis, and can cure tinea manus and pedis in a painless, itchy and unconscious process.

Below in conjunction with embodiment the present invention is further described:

Specific implementation method:

Embodiment 1: a kind of painless nano-emulsion for treating tinea manus and pedis is characterized in that: it is composed of snake oil rhubarb natural animal and plant mineral element nano-emulsion according to the following mass proportioning %

Embodiment 2: a kind of painless nano emulsifiable paste for treating tinea manus and pedis, is characterized in that: by marmot oil centipede natural animal and plant mineral element nano emulsifiable paste, form % by following mass proportioning

Embodiment 3: a kind of painless nano emulsifiable cream for treating tinea manus and pedis, is characterized in that: by the natural animal and plant mineral element nano emulsifiable cream of muscara amitabha monk, form % by following mass proportioning

Embodiment 4: a kind of painless nano emulsifiable cream for treating tinea manus and pedis, is characterized in that: by the natural animal and plant mineral element nano emulsifiable paste of snake bark pine and cypress leaf, form % by following mass proportioning

Embodiment 5: a kind of painless nano emulsifiable cream for treating tinea manus and pedis, is characterized in that: by cicada slough propolis natural animal and plant mineral element nano emulsifiable paste, form by following mass proportioning %

Embodiment 6: a kind of painless nano emulsifiable paste for treating tinea manus and pedis, is characterized in that: by mylabris medical stone natural animal and plant mineral element nano emulsifiable paste, is formed by following mass proportioning %

Embodiment 7: a kind of painless nano-emulsion for treating tinea manus and pedis is characterized in that: it is composed of natural animal and plant mineral element nano-emulsion of snake gall cream white moss cortex, and is formed by the following mass proportioning %

Claims (7)

1. control a tinea manus and pedis Silent Neuritis nanometer emulsifiable paste, it is characterized in that: by Adeps Serpentis Radix Et Rhizoma Rhei natural animal-plant mineral element nanometer emulsifiable paste, by following masses proportioning composition %

。

2. control a tinea manus and pedis Silent Neuritis nanometer emulsifiable paste, it is characterized in that: by woodchuck oil Scolopendra natural animal-plant mineral element nanometer emulsifiable paste, by following masses proportioning composition %

。

3. control a tinea manus and pedis Silent Neuritis nanometer emulsifiable paste, it is characterized in that: by Moschus Lithargyrum natural animal-plant mineral element nanometer emulsifiable paste, by following masses proportioning composition %

。

4. control a tinea manus and pedis Silent Neuritis nanometer emulsifiable paste, it is characterized in that: by Periostracum Serpentis Folium Pini and Cacumen Platycladi natural animal-plant mineral element nanometer emulsifiable paste, by following masses proportioning composition %

。

5. control a tinea manus and pedis Silent Neuritis nanometer emulsifiable paste, it is characterized in that: by Periostracum Cicadae propolis natural animal-plant mineral element nanometer emulsifiable paste, by following masses proportioning composition %

。

6. control a tinea manus and pedis Silent Neuritis nanometer emulsifiable paste, it is characterized in that: by Mylabris Maifanitum natural animal-plant mineral element nanometer emulsifiable paste, by following masses proportioning composition %

。

7. control a tinea manus and pedis Silent Neuritis nanometer emulsifiable paste, it is characterized in that: by Fel Serpentis frost Cortex Dictamni natural animal-plant mineral element nanometer emulsifiable paste, by following masses proportioning composition %