[go: up one dir, main page]

CL2017002173A1 - Método de fermentación mixotrófica para producir acetona, isopropanol, acido butírico y otros bioproductos, y mezclas de los mismos. - Google Patents

Método de fermentación mixotrófica para producir acetona, isopropanol, acido butírico y otros bioproductos, y mezclas de los mismos.

Info

Publication number
CL2017002173A1
CL2017002173A1 CL2017002173A CL2017002173A CL2017002173A1 CL 2017002173 A1 CL2017002173 A1 CL 2017002173A1 CL 2017002173 A CL2017002173 A CL 2017002173A CL 2017002173 A CL2017002173 A CL 2017002173A CL 2017002173 A1 CL2017002173 A1 CL 2017002173A1
Authority
CL
Chile
Prior art keywords
fermentation
mixtures
raw material
bioproducts
isopropanol
Prior art date
Application number
CL2017002173A
Other languages
English (en)
Inventor
Bryan P Tracy
Shawn William Jones
Aharon M Eyal
Original Assignee
White Dog Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by White Dog Labs Inc filed Critical White Dog Labs Inc
Publication of CL2017002173A1 publication Critical patent/CL2017002173A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26Ketones
    • C12P7/28Acetone-containing products
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • C12P7/065Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16Butanols
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/54Acetic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56Lactic acid
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

<p>Método de fermentación mixotrófica realizado para fabricar uno o más bioproductos tales como alcoholes, ácidos orgánicos de menos de 7 carbonos, acetona, 2,3-butanodiol y mezclas de los mismos con un microorganismo. El método de fermentación mixotrófica incluye proporcionar un organismo aislado y proporcionar una primera materia prima y una segunda materia prima para su uso en un medio de fermentación. La primera materia prima incluye una fuente de carbono que se metaboliza por la forma natural del organismo a una tasa de menos de 0,01 g/h/g de la masa celular, y la segunda materia prima incluye CO, CO2, carbonato, bicarbonato, H2, glicerol, metanol, formiato, urea o mezclas de los mismos. El método de fermentación mixotrófica también incluye el cultivo del organismo en el medio de fermentación, y por esto ambas materias primas se metabolizan y se forma un caldo de fermentación, el caldo que tiene al menos un bioproducto. Opcionalmente, el bioproducto puede separarse del caldo.</p>
CL2017002173A 2015-02-27 2017-08-25 Método de fermentación mixotrófica para producir acetona, isopropanol, acido butírico y otros bioproductos, y mezclas de los mismos. CL2017002173A1 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562121871P 2015-02-27 2015-02-27
US201562183034P 2015-06-22 2015-06-22
US201562199548P 2015-07-31 2015-07-31
US201562209133P 2015-08-24 2015-08-24
US201562265239P 2015-12-09 2015-12-09

Publications (1)

Publication Number Publication Date
CL2017002173A1 true CL2017002173A1 (es) 2018-04-20

Family

ID=56789863

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017002173A CL2017002173A1 (es) 2015-02-27 2017-08-25 Método de fermentación mixotrófica para producir acetona, isopropanol, acido butírico y otros bioproductos, y mezclas de los mismos.

Country Status (7)

Country Link
US (1) US9938542B2 (es)
EP (1) EP3273782B9 (es)
CN (1) CN107404882A (es)
AU (1) AU2016222565A1 (es)
CL (1) CL2017002173A1 (es)
MX (1) MX387737B (es)
WO (1) WO2016138372A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3341471A4 (en) * 2015-08-24 2020-07-22 White Dog Labs, Inc. MICROBIAL ORGANISMS FOR CONVERTING ACETYL-COA IN CROTYL ALCOHOL AND METHOD FOR PRODUCING CROTYL ALCOHOL
WO2017059244A1 (en) * 2015-10-02 2017-04-06 White Dog Labs, Inc. A method for producing a bioproduct selected from acetone, isopropanol and combinations thereof
CN108884476B (zh) 2016-02-19 2022-10-18 英威达纺织(英国)有限公司 用于提升的碳利用率的生物催化工艺和材料
US10934562B2 (en) 2016-05-23 2021-03-02 White Dog Labs, Inc. Integrated mixotrophic fermentation method
WO2017210296A1 (en) * 2016-06-01 2017-12-07 White Dog Labs, Inc. Supplemented mixotrophic fermentation method
US11649472B2 (en) 2017-06-30 2023-05-16 Massachusetts Institute Of Technology Controlling metabolism by substrate cofeeding
EP3833771A1 (en) 2018-08-08 2021-06-16 Jupeng Bio, Inc. Carbon dioxide bioconversion process
CN114561416B (zh) * 2022-04-27 2022-07-15 深圳中科翎碳生物科技有限公司 利用电能固定co2及合成异丙醇的工程菌及构建方法
KR102804563B1 (ko) * 2022-10-07 2025-05-12 한국과학기술연구원 아세토젠 균주의 흡착수지가 보충된 반혼합영양발효를 통해 탄소화합물을 생산하는 방법
WO2024231219A1 (en) * 2023-05-11 2024-11-14 Evonik Operations Gmbh Biotechnological production of acetone

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5173429A (en) * 1990-11-09 1992-12-22 The Board Of Trustees Of The University Of Arkansas Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism
FR2808689B1 (fr) * 2000-05-11 2004-09-03 Agronomique Inst Nat Rech Utilisation de souches acetogenes hydrogenotrophes pour la prevention ou le traitement de troubles digestifs
ITBO20050217A1 (it) 2005-04-08 2006-10-09 Enrico Petazzoni Cattura della co2 da gas esausti e suo uso nella digestione anaerobica di materiale organico
US20080274526A1 (en) 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of isobutanol
JP5180060B2 (ja) 2006-02-24 2013-04-10 三菱化学株式会社 有機酸生産菌及び有機酸の製造法
NZ553984A (en) 2007-03-19 2009-07-31 Lanzatech New Zealand Ltd Alcohol production process
US20080274522A1 (en) 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of 2-butanone
US8426174B2 (en) 2007-05-02 2013-04-23 Butamax(Tm) Advanced Biofuels Llc Method for the production of 2-butanol
US8426173B2 (en) 2007-05-02 2013-04-23 Butamax (Tm) Advanced Biofuels Llc Method for the production of 1-butanol
US8309323B2 (en) 2007-11-13 2012-11-13 Synthetic Genomics, Inc. Dimethyloctane as an advanced biofuel
JP2011509691A (ja) 2008-01-22 2011-03-31 ジェノマティカ, インコーポレイテッド 合成ガスまたは他のガス状炭素源およびメタノールを利用するための方法および生物体
WO2009103026A1 (en) 2008-02-15 2009-08-20 Gevo, Inc. Engineered microorganisms for producing isopropanol
EP2250274B1 (en) 2008-03-12 2015-04-08 Lanzatech New Zealand Limited Microbial alcohol production process
EP2334800B1 (en) 2008-09-10 2018-12-26 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
KR20110097951A (ko) 2008-12-16 2011-08-31 게노마티카 인코포레이티드 합성가스와 다른 탄소원을 유용 제품으로 전환시키기 위한 미생물 및 방법
DE102009002583A1 (de) * 2009-04-23 2010-10-28 Evonik Degussa Gmbh Zellen und Verfahren zur Herstellung von Aceton
US20130217084A1 (en) 2009-05-15 2013-08-22 Zhiyou Wen Production of omega-3 fatty acids from crude glycerol
US8129169B2 (en) 2009-06-04 2012-03-06 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
NZ624392A (en) 2009-08-21 2015-12-24 Lallemand Hungary Liquidity Man Llc Production of propanols, alcohols, and polyols in consolidated bioprocessing organisms
CN102625845A (zh) 2009-09-09 2012-08-01 基因组股份公司 协同产生异丙醇与伯醇,二元醇和酸的微生物和方法
CN102762735B (zh) 2009-10-13 2016-08-03 基因组股份公司 生产1,4-丁二醇、4-羟基丁醛、4-羟基丁酰-coa、腐胺和相关化合物的微生物及其相关方法
CA2781400A1 (en) 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an organic acid and/or related chemicals
CA2781443A1 (en) 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Methods, systems, and compositions for microbial bio-production of biomolecules using syngas components, or sugars, as feedstocks
SG181607A1 (en) 2009-12-10 2012-07-30 Genomatica Inc Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol
EP2529023A4 (en) 2010-01-27 2015-06-10 Opx Biotechnologies Inc MICRO-ORGANISM MANUFACTURE FROM HIGH-FLOW CHEMICAL PRODUCTS AND CORRESPONDING COMPOSITIONS, METHODS AND SYSTEMS
US8637286B2 (en) 2010-02-23 2014-01-28 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
SG185432A1 (en) 2010-05-05 2012-12-28 Genomatica Inc Microorganisms and methods for the biosynthesis of butadiene
EP2607340B1 (en) 2010-07-26 2017-09-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
WO2012034023A2 (en) * 2010-09-10 2012-03-15 University Of Delaware Recombinant clostridia that fix co2 and co and uses thereof
WO2012080421A1 (en) 2010-12-17 2012-06-21 Total Petrochemicals Research Feluy Process for producing propylene from syngas via fermentative propanol production and dehydration
US20120196339A1 (en) * 2011-01-31 2012-08-02 Los Alamos National Security Llc Production of industrially relevant compounds in prokaryotic organisms
US9410130B2 (en) * 2011-02-25 2016-08-09 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
EP2694663A4 (en) 2011-04-01 2015-04-29 Genomatica Inc MICRO-ORGANISMS FOR THE PREPARATION OF METHACRYLIC ACID AND METHACRYLATE ESTERS AND METHODS RELATED THEREWITH
WO2012177599A2 (en) 2011-06-22 2012-12-27 Genomatica, Inc. Microorganisms for producing n-propanol 1, 3-propanediol, 1,2-propanediol or glycerol and methods related thereto
WO2012177619A2 (en) 2011-06-22 2012-12-27 Genomatica, Inc. Microorganisms for producing 1,3-butanediol and methods related thereto
AU2012272856A1 (en) 2011-06-22 2013-05-02 Genomatica, Inc. Microorganisms for producing 1,4-butanediol and methods related thereto
US20120329111A1 (en) 2011-06-22 2012-12-27 Genomatica, Inc. Microorganisms for Producing Cyclohexanone and Methods Related Thereto
US9169486B2 (en) 2011-06-22 2015-10-27 Genomatica, Inc. Microorganisms for producing butadiene and methods related thereto
AU2012273093A1 (en) 2011-06-22 2013-05-02 Genomatica, Inc. Microorganisms for producing 6-aminocaproic acid
WO2012177601A2 (en) 2011-06-22 2012-12-27 Genomatica, Inc. Microorganisms for producing isobutanol and methods related thereto
EP2734627A4 (en) 2011-07-20 2015-07-22 Genomatica Inc METHODS FOR INCREASING PRODUCT OUTPUTS
JP6440497B2 (ja) 2011-10-19 2018-12-19 サイエンティスト・オブ・フォーチュン・ソシエテ・アノニム ブタジエンの酵素的製造のための方法
BR112014010448A2 (pt) 2011-11-02 2017-04-18 Genomatica Inc microorganismos e métodos para a produção de caprolactona
EP2791342B1 (en) 2011-12-16 2020-04-29 Braskem S.A. Modified microorganisms and methods of making butadiene using same
NZ700609A (en) 2012-04-05 2016-07-29 Lanzatech New Zealand Ltd Enzyme-altered metabolite activity
WO2013181647A2 (en) 2012-06-01 2013-12-05 Danisco Us Inc. Compositions and methods of producing isoprene and/or industrrial bio-products using anaerobic microorganisms
WO2013184602A2 (en) 2012-06-04 2013-12-12 Genomatica, Inc. Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds
US9752164B2 (en) 2012-06-15 2017-09-05 Microvi Biotech, Inc. Enhanced efficiency ethanol and sugar conversion processes
US9200297B2 (en) 2012-10-03 2015-12-01 Green Cellulosity Corporation Acidogenic clostridia and processes of using thereof for producing volatile fatty acids
KR20210118216A (ko) 2012-10-15 2021-09-29 게노마티카 인코포레이티드 특정 길이의 지방 알콜 및 관련 화합물의 생산을 위한 미생물 및 방법
US20140193871A1 (en) 2013-01-04 2014-07-10 Industrial Technology Research Institute Method for enhancing carbon biofixation
ITMI20130109A1 (it) 2013-01-24 2014-07-25 Consiglio Nazionale Ricerche Procedimento per il sequestro di anidride carbonica e la produzione fermentativa di composti organici
US20150050708A1 (en) * 2013-03-15 2015-02-19 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
WO2014193473A1 (en) 2013-05-31 2014-12-04 E. I. Du Pont De Nemours And Company Recombinant anaerobic acetogenic bacteria for production of isoprene and/or industrial bio-products using synthesis gas
KR102316945B1 (ko) * 2013-10-17 2021-10-26 란자테크 뉴질랜드 리미티드 발효에서 개선된 탄소 포집
KR20160093648A (ko) * 2013-12-03 2016-08-08 란자테크 뉴질랜드 리미티드 케톤을 생산하기 위한 방법 및 미생물

Also Published As

Publication number Publication date
BR112017018257A2 (pt) 2018-04-10
EP3273782B1 (en) 2022-05-04
EP3273782A1 (en) 2018-01-31
EP3273782A4 (en) 2018-10-24
WO2016138372A1 (en) 2016-09-01
MX2017010859A (es) 2018-08-15
AU2016222565A1 (en) 2017-09-28
US20160251683A1 (en) 2016-09-01
MX387737B (es) 2025-03-18
EP3273782B9 (en) 2022-07-13
US9938542B2 (en) 2018-04-10
CN107404882A (zh) 2017-11-28
CA2977593A1 (en) 2016-09-01

Similar Documents

Publication Publication Date Title
CL2017002173A1 (es) Método de fermentación mixotrófica para producir acetona, isopropanol, acido butírico y otros bioproductos, y mezclas de los mismos.
SG10201809452RA (en) Cell culture compositions with antioxidants and methods for polypeptide production
MX353489B (es) Metodo para producir eritrocitos sin celulas alimentadoras.
MX2019002495A (es) Metodos para producir virus para la produccion de vacunas.
WO2019014310A8 (en) Biological methods for preparing terpenes
CA2830080C (en) Generation of nk cells and nk-cell progenitors
BR112018002214A2 (pt) ?métodos para cultivar células e para produzir uma proteína, meios de cultura de células cho e de batelada alimentada e/ou alimentação, e, alimentação de cultura de células cho?
MX2018010529A (es) Composiciones y metodos para la produccion y administracion de acido ribonucleico.
EA202091407A1 (ru) Состав бессывороточной среды для культивирования клеток и способы его применения
MX2016001881A (es) Metodos para la mejora de rendimiento y produccion de producto en un microorganismo a traves del reciclaje de glicerol.
MX2016004564A (es) Cultivo celular metabolicamente optimizado.
WO2013022998A3 (en) Production of carboxylates and methane from biomass waste
EP4446338A3 (en) Cells and method of cell culture
ECSP10010221A (es) Aditivo para proceso de hidroconversión y método para preparación y uso del mismo
BR112017005354A2 (pt) métodos de criação de um banco de células de densidade ultra-alta
MX2012014906A (es) Fermentacion de biomasa.
BR112013028544A2 (pt) método para produzir um composto derivado de acetil-coa heterólogo
BR112016005456A2 (pt) método para produzir um l-aminoácido por um método de fermentação, e, dna isolado
BR112013010813A2 (pt) células fúngicas, misturadas de enzimas, métodos para geração de glicose e meio de fermentação.
MX374056B (es) Microorganismo para la produccion de metionina con actividad de metionina sintasa y eflujo de metionina mejorados.
MY178060A (en) Methods of preparing a poloxamer for use in cell culture medium
MX2016014718A (es) Cocultivo de propionibacteria y levadura.
BR112016023893A2 (pt) processo de fermentação por extração e preenchimento a alta densidade celular
MY179877A (en) Method for producing 2,3-butanediol
MD4389B1 (ro) Procedeu de obţinere a biometanului