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CL2011002739A1 - Compuestos derivados de 3-(1h-pirrolo[2,3-b]piridina-3-carbonil)-bencenosulfonamida; composicion farmaceutica que los comprende; kit; y su uso como inhibidores de raf para el tratamiento de una enfermedad o condicion seleccionada de melanoma, glioma, glioblastoma multiforme, cancer colorrectal, cancer de pulmon, entre otras. - Google Patents

Compuestos derivados de 3-(1h-pirrolo[2,3-b]piridina-3-carbonil)-bencenosulfonamida; composicion farmaceutica que los comprende; kit; y su uso como inhibidores de raf para el tratamiento de una enfermedad o condicion seleccionada de melanoma, glioma, glioblastoma multiforme, cancer colorrectal, cancer de pulmon, entre otras.

Info

Publication number
CL2011002739A1
CL2011002739A1 CL2011002739A CL2011002739A CL2011002739A1 CL 2011002739 A1 CL2011002739 A1 CL 2011002739A1 CL 2011002739 A CL2011002739 A CL 2011002739A CL 2011002739 A CL2011002739 A CL 2011002739A CL 2011002739 A1 CL2011002739 A1 CL 2011002739A1
Authority
CL
Chile
Prior art keywords
benzenesulfonamide
pyrrolo
glioma
melanoma
carbonyl
Prior art date
Application number
CL2011002739A
Other languages
English (en)
Inventor
Prabha N Ibrahim
Wayne Shi Songyuan Wu Guoxian Cho Hanna Spevak
Original Assignee
Plexxikon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42236712&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2011002739(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Plexxikon Inc filed Critical Plexxikon Inc
Publication of CL2011002739A1 publication Critical patent/CL2011002739A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Compuestos derivados de 3-(1h-pirrolo[2,3-b]piridina-3-carbonil)-bencenosulfonamida; composición farmacéutica que los comprende; kit; y su uso para el tratamiento de una enfermedad o condición seleccionada de melanoma, glioma, glioblastoma multiforme, cáncer colorrectal, cáncer de pulmón, entre otras.
CL2011002739A 2009-05-06 2011-11-03 Compuestos derivados de 3-(1h-pirrolo[2,3-b]piridina-3-carbonil)-bencenosulfonamida; composicion farmaceutica que los comprende; kit; y su uso como inhibidores de raf para el tratamiento de una enfermedad o condicion seleccionada de melanoma, glioma, glioblastoma multiforme, cancer colorrectal, cancer de pulmon, entre otras. CL2011002739A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17605409P 2009-05-06 2009-05-06

Publications (1)

Publication Number Publication Date
CL2011002739A1 true CL2011002739A1 (es) 2012-04-09

Family

ID=42236712

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2011002739A CL2011002739A1 (es) 2009-05-06 2011-11-03 Compuestos derivados de 3-(1h-pirrolo[2,3-b]piridina-3-carbonil)-bencenosulfonamida; composicion farmaceutica que los comprende; kit; y su uso como inhibidores de raf para el tratamiento de una enfermedad o condicion seleccionada de melanoma, glioma, glioblastoma multiforme, cancer colorrectal, cancer de pulmon, entre otras.

Country Status (23)

Country Link
US (3) US8198273B2 (es)
EP (2) EP2427462A1 (es)
JP (2) JP2012526128A (es)
KR (1) KR20140014386A (es)
CN (1) CN102459262A (es)
AR (1) AR076749A1 (es)
AU (1) AU2010246005A1 (es)
BR (1) BRPI1013843A2 (es)
CA (1) CA2759997A1 (es)
CL (1) CL2011002739A1 (es)
CR (1) CR20110562A (es)
EC (1) ECSP11011437A (es)
IL (1) IL215908A0 (es)
MA (1) MA34042B1 (es)
MX (1) MX2011011737A (es)
NI (1) NI201100189A (es)
NO (1) NO20111508A1 (es)
PE (1) PE20120518A1 (es)
RU (1) RU2011149485A (es)
SG (1) SG175810A1 (es)
TW (1) TW201041888A (es)
WO (2) WO2010129570A1 (es)
ZA (1) ZA201108124B (es)

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Also Published As

Publication number Publication date
IL215908A0 (en) 2012-01-31
NO20111508A1 (no) 2011-12-02
ECSP11011437A (es) 2011-12-30
CA2759997A1 (en) 2010-11-11
BRPI1013843A2 (pt) 2016-04-12
EP2427462A1 (en) 2012-03-14
NI201100189A (es) 2012-01-11
WO2010129567A1 (en) 2010-11-11
US20120122860A1 (en) 2012-05-17
EP2427433A1 (en) 2012-03-14
CN102459262A (zh) 2012-05-16
US8198273B2 (en) 2012-06-12
MA34042B1 (fr) 2013-03-05
ZA201108124B (en) 2014-04-30
KR20140014386A (ko) 2014-02-06
SG175810A1 (en) 2011-12-29
CR20110562A (es) 2012-02-09
US20120245174A1 (en) 2012-09-27
JP2012526127A (ja) 2012-10-25
TW201041888A (en) 2010-12-01
US20100286142A1 (en) 2010-11-11
MX2011011737A (es) 2011-12-08
AR076749A1 (es) 2011-07-06
AU2010246005A1 (en) 2011-12-01
RU2011149485A (ru) 2013-06-20
JP2012526128A (ja) 2012-10-25
PE20120518A1 (es) 2012-05-24
WO2010129570A1 (en) 2010-11-11

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