CL2008002088A1 - Compuestos derivados de fenilo sustituido, moduladores del receptor de histamina 3; proceso de preparacion; composicion farmaceutica; y uso en el tratamiento de trastornos cognitivos tales como demencia, alzheimer, entre otros. - Google Patents
Compuestos derivados de fenilo sustituido, moduladores del receptor de histamina 3; proceso de preparacion; composicion farmaceutica; y uso en el tratamiento de trastornos cognitivos tales como demencia, alzheimer, entre otros.Info
- Publication number
- CL2008002088A1 CL2008002088A1 CL200802088A CL2008002088A CL2008002088A1 CL 2008002088 A1 CL2008002088 A1 CL 2008002088A1 CL 200802088 A CL200802088 A CL 200802088A CL 2008002088 A CL2008002088 A CL 2008002088A CL 2008002088 A1 CL2008002088 A1 CL 2008002088A1
- Authority
- CL
- Chile
- Prior art keywords
- phenyll
- dementia
- alzheimer
- replaced
- treatment
- Prior art date
Links
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 title 2
- 206010012289 Dementia Diseases 0.000 title 1
- 208000010877 cognitive disease Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 229960001340 histamine Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95974107P | 2007-07-16 | 2007-07-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2008002088A1 true CL2008002088A1 (es) | 2008-09-05 |
Family
ID=39708793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200802088A CL2008002088A1 (es) | 2007-07-16 | 2008-07-15 | Compuestos derivados de fenilo sustituido, moduladores del receptor de histamina 3; proceso de preparacion; composicion farmaceutica; y uso en el tratamiento de trastornos cognitivos tales como demencia, alzheimer, entre otros. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7803825B2 (es) |
| EP (1) | EP2170875A1 (es) |
| JP (1) | JP2010533725A (es) |
| AR (1) | AR067549A1 (es) |
| CA (1) | CA2693138A1 (es) |
| CL (1) | CL2008002088A1 (es) |
| PA (1) | PA8790101A1 (es) |
| PE (1) | PE20090812A1 (es) |
| TW (1) | TW200920356A (es) |
| WO (1) | WO2009012252A1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100016609A1 (en) * | 2008-07-15 | 2010-01-21 | Wyeth | Methods for the preparation of azole compounds |
| AU2010264422B2 (en) * | 2009-06-26 | 2014-12-18 | Sanofi | Novel fumarate salts of a histamine H3 receptor antagonist |
| EA021047B1 (ru) * | 2009-07-15 | 2015-03-31 | Янссен Фармасьютикалз, Инк. | Замещенные производные триазола и имидазола в качестве модуляторов гамма-секретазы |
| US20120208827A1 (en) * | 2009-10-27 | 2012-08-16 | Glaxosmithkline Llc | Benzimidazoles as fatty acid synthase inhibitors |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| CN103570705B (zh) * | 2012-07-18 | 2017-01-25 | 中国医学科学院医药生物技术研究所 | 取代的n‑((1＇,3＇‑杂唑‑4＇‑基)‑甲基)‑4‑苯甲酰基六氢吡啶类化合物及其用途 |
| MX2018011214A (es) | 2016-03-15 | 2019-03-28 | Bayer Cropscience Ag | Sulfonamidas sustituidas para controlar plagas animales. |
| MX2023001758A (es) * | 2020-08-11 | 2023-04-11 | Univ Michigan State | Potenciadores de proteasoma y usos de los mismos. |
| EP4467539A4 (en) * | 2022-01-21 | 2025-11-05 | Pasteur Institut Korea | Oxazole-derived compound with antibacterial activity and its medical use |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1416872A (en) | 1972-03-10 | 1975-12-10 | Wyeth John & Brother Ltd | 4-aminoquinoline derivatives |
| US3933829A (en) | 1974-08-22 | 1976-01-20 | John Wyeth & Brother Limited | 4-Aminoquinoline derivatives |
| US4168853A (en) * | 1977-06-08 | 1979-09-25 | Vetco, Inc. | Shiftable ring gasket retainer for flanged connectors |
| US4166853A (en) | 1978-05-05 | 1979-09-04 | The Upjohn Company | Antihypertensive 7-trifluoromethyl-4-aminoquinolones |
| US4159331A (en) | 1978-05-05 | 1979-06-26 | The Upjohn Company | Antihypertensive 4-aminoquinolines |
| CN1052224C (zh) | 1993-04-07 | 2000-05-10 | 大塚制药株式会社 | 哌啶衍生物、含有它的外周血管舒张剂及其应用 |
| IL117149A0 (en) | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
| WO1998048800A1 (en) | 1997-05-01 | 1998-11-05 | Eli Lilly And Company | Antithrombotic agents |
| AU1734401A (en) | 1999-12-09 | 2001-06-18 | Mitsubishi Pharma Corporation | Carboxyamido derivatives |
| ES2325477T3 (es) | 2000-03-31 | 2009-09-07 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Indoles sustituidos por fenilo como antagonistas del receptor de histamina h3. |
| HN2002000156A (es) | 2001-07-06 | 2003-11-27 | Inc Agouron Pharmaceuticals | Derivados de benzamida tiazol y composiciones farmaceuticas para inhibir la proliferacion de celulas y metodos para su utilización. |
| EA007987B1 (ru) | 2002-03-29 | 2007-02-27 | Чирон Корпорейшн | Замещённые бензазолы и их применение в качестве ингибиторов киназы raf |
| EP1603917B1 (en) | 2003-03-14 | 2010-11-24 | MediGene Ltd. | Immunomodulating heterocyclic compounds |
| US7572784B2 (en) | 2004-05-14 | 2009-08-11 | Millennium Pharmaceuticals, Inc. | Compounds and methods for inhibiting mitotic progression |
| TW200602314A (en) | 2004-05-28 | 2006-01-16 | Tanabe Seiyaku Co | A novel pyrrolidine compound and a process for preparing the same |
| US20060014733A1 (en) | 2004-07-19 | 2006-01-19 | Pfizer Inc | Histamine-3 agonists and antagonists |
| BRPI0513777A (pt) | 2004-07-26 | 2008-05-13 | Lilly Co Eli | composto ou um sal do mesmo, composição farmacêutica, e, uso de um composto ou de um sal do mesmo |
| CA2577061C (en) | 2004-08-23 | 2014-02-18 | Eli Lilly And Company | Histamine h3 receptor agents, preparation and therapeutic uses |
| UY29149A1 (es) | 2004-10-07 | 2006-05-31 | Boehringer Ingelheim Int | Tiazolil-dihidro-indazoles |
| US7381732B2 (en) | 2004-10-26 | 2008-06-03 | Bristol-Myers Squibb Company | Pyrazolobenzamides and derivatives as factor Xa inhibitors |
| MX2007008843A (es) | 2005-01-21 | 2007-08-22 | Schering Corp | Derivados de imidazol y bencimidazol utiles como antagonistas de histamina h3. |
| US20070032475A1 (en) | 2005-04-15 | 2007-02-08 | Ye Xiaocong M | Novel compounds useful for bradykinin B1 receptor antagonism |
| JP2009530274A (ja) | 2006-03-15 | 2009-08-27 | ワイス | ヒスタミン−３アンタゴニストとしてのｎ−置換−アザシクリルアミン化合物 |
| AU2007228778A1 (en) | 2006-03-20 | 2007-09-27 | Glaxo Group Limited | Compounds which potentiate AMPA receptor and uses thereof in medicine |
| US20070238718A1 (en) | 2006-04-06 | 2007-10-11 | Matthias Grauert | Thiazolyl-dihydro-indazole |
| PE20081152A1 (es) | 2006-10-06 | 2008-08-10 | Wyeth Corp | Azaciclilaminas n-sustituidas como antagonistas de histamina-3 |
-
2008
- 2008-07-15 EP EP08781841A patent/EP2170875A1/en not_active Withdrawn
- 2008-07-15 CL CL200802088A patent/CL2008002088A1/es unknown
- 2008-07-15 PE PE2008001183A patent/PE20090812A1/es not_active Application Discontinuation
- 2008-07-15 WO PCT/US2008/070048 patent/WO2009012252A1/en not_active Ceased
- 2008-07-15 CA CA2693138A patent/CA2693138A1/en not_active Abandoned
- 2008-07-15 JP JP2010517115A patent/JP2010533725A/ja not_active Withdrawn
- 2008-07-15 AR ARP080103037A patent/AR067549A1/es unknown
- 2008-07-15 US US12/173,255 patent/US7803825B2/en not_active Expired - Fee Related
- 2008-07-16 PA PA20088790101A patent/PA8790101A1/es unknown
- 2008-07-16 TW TW097127000A patent/TW200920356A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010533725A (ja) | 2010-10-28 |
| US20090023707A1 (en) | 2009-01-22 |
| PE20090812A1 (es) | 2009-06-14 |
| CA2693138A1 (en) | 2009-01-22 |
| EP2170875A1 (en) | 2010-04-07 |
| PA8790101A1 (es) | 2009-02-09 |
| AR067549A1 (es) | 2009-10-14 |
| US7803825B2 (en) | 2010-09-28 |
| TW200920356A (en) | 2009-05-16 |
| WO2009012252A1 (en) | 2009-01-22 |
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