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CL2008001671A1 - Compuestos derivados de piperidina/piperazina inhibidores de dgat1, composicion farmaceutica que los comprende; y su uso en el tratamiento de enfermedades metabolicas especialmente diabetes. - Google Patents

Compuestos derivados de piperidina/piperazina inhibidores de dgat1, composicion farmaceutica que los comprende; y su uso en el tratamiento de enfermedades metabolicas especialmente diabetes.

Info

Publication number
CL2008001671A1
CL2008001671A1 CL2008001671A CL2008001671A CL2008001671A1 CL 2008001671 A1 CL2008001671 A1 CL 2008001671A1 CL 2008001671 A CL2008001671 A CL 2008001671A CL 2008001671 A CL2008001671 A CL 2008001671A CL 2008001671 A1 CL2008001671 A1 CL 2008001671A1
Authority
CL
Chile
Prior art keywords
piperidine
treatment
pharmaceutical composition
metabolic diseases
derivative compounds
Prior art date
Application number
CL2008001671A
Other languages
English (en)
Inventor
Lieven Meerpoel
Jean Pierre Andre Marc Bongartz
Joannes Theodorus Maria Linders
Lommen Guy Rosalia Eugeen Van
Go
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39865125&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2008001671(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CL2008001671A1 publication Critical patent/CL2008001671A1/es

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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
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    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
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Abstract

Compuestos derivados de piperidina/piperazina inhibidores de dgat, procedimiento para su preparación, composición farmacéutica que comprende a estos compuestos y su uso para el tratamiento de trastornos del metabolismo como la obesidad, diabetes mellitus tipo II, dislipidemia, entre otras.
CL2008001671A 2007-06-08 2008-06-06 Compuestos derivados de piperidina/piperazina inhibidores de dgat1, composicion farmaceutica que los comprende; y su uso en el tratamiento de enfermedades metabolicas especialmente diabetes. CL2008001671A1 (es)

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RU2009148320A (ru) 2011-07-20
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JP2010529089A (ja) 2010-08-26
WO2008148868A1 (en) 2008-12-11
WO2008148868A8 (en) 2009-03-05
CA2687754C (en) 2015-12-08
CN101678019A (zh) 2010-03-24
PE20090362A1 (es) 2009-04-04
AR066911A1 (es) 2009-09-23
CA2687754A1 (en) 2008-12-11
PA8783601A1 (es) 2009-01-23
US8981094B2 (en) 2015-03-17
ES2536406T3 (es) 2015-05-25
RU2470017C2 (ru) 2012-12-20
JP5385263B2 (ja) 2014-01-08
TW200911771A (en) 2009-03-16
TWI426070B (zh) 2014-02-11
CN101678019B (zh) 2016-03-30
EP2152270A1 (en) 2010-02-17
US20100190789A1 (en) 2010-07-29
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