BRPI0907247A2 - Métodos para preparar biopterina e para preparar tetraidrobiopterina - Google Patents

Métodos para preparar biopterina e para preparar tetraidrobiopterina

Info

Publication number: BRPI0907247A2
Authority: BR; Brazil
Prior art keywords: preparing; biopterin; methods; tetrahydrobiopterin; preparing tetrahydrobiopterin
Prior art date: 2008-01-07

Application number

BRPI0907247-0A

Other languages

English (en)

Inventor

Mark Henderson

Steven Jungles

Gabriele Roidl

Robert Baffi

Adriano Indolese

Christian Müller

Philipp Schmidt

Stefan Kaiser

Original Assignee

Biomarin Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-01-07

Filing date

2009-01-06

Publication date

2015-07-14

2009-01-06 Application filed by Biomarin Pharm Inc filed Critical Biomarin Pharm Inc

2015-07-14 Publication of BRPI0907247A2 publication Critical patent/BRPI0907247A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

BRPI0907247-0A 2008-01-07 2009-01-06 Métodos para preparar biopterina e para preparar tetraidrobiopterina BRPI0907247A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US1952808P	2008-01-07	2008-01-07
US4690908P	2008-04-22	2008-04-22
PCT/US2009/000030 WO2009088979A1 (en)	2008-01-07	2009-01-06	Method of synthesizing tetrahydrobiopterin

Publications (1)

Publication Number	Publication Date
BRPI0907247A2 true BRPI0907247A2 (pt)	2015-07-14

Family

ID=40428295

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0907247-0A BRPI0907247A2 (pt)	2008-01-07	2009-01-06	Métodos para preparar biopterina e para preparar tetraidrobiopterina

Country Status (16)

Country	Link
US (1)	US8178670B2 (pt)
EP (1)	EP2240484A1 (pt)
JP (1)	JP2011508781A (pt)
KR (1)	KR20100101006A (pt)
CN (1)	CN101959891A (pt)
AR (1)	AR070109A1 (pt)
AU (1)	AU2009204476A1 (pt)
BR (1)	BRPI0907247A2 (pt)
CA (1)	CA2711444C (pt)
CL (2)	CL2009000007A1 (pt)
IL (1)	IL206845A0 (pt)
MX (1)	MX2010007452A (pt)
PE (1)	PE20091314A1 (pt)
RU (1)	RU2010133160A (pt)
TW (1)	TW200942542A (pt)
WO (1)	WO2009088979A1 (pt)

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TWI481612B (zh) *	2010-10-15	2015-04-21	Innopharmax Inc	（６ｒ）－四氫生物喋呤鹽酸鹽的製備方法
KR20140007431A (ko)	2011-02-18	2014-01-17	알렉시온 파마 인터내셔널 에스에이알엘	몰리브도프테린 전구체 z 유도체들의 합성 방법
CN102627644B (zh)	2012-04-10	2014-04-16	凯莱英医药集团（天津）股份有限公司	一种通过直接手性合成方法制备二盐酸沙丙蝶呤的方法
CN102633799B (zh) *	2012-04-10	2014-06-25	凯莱英医药集团（天津）股份有限公司	一种从消旋体中间体拆分路线合成二盐酸沙丙蝶呤的方法
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KR102604510B1 (ko)	2016-07-26	2023-11-23	바이오마린 파머수티컬 인크.	신규 아데노-관련 바이러스 캡시드 단백질
CN109776540B (zh) *	2017-11-15	2021-07-06	北京启慧生物医药有限公司	一种盐酸沙丙蝶呤的制备方法
US11739345B2 (en)	2018-05-09	2023-08-29	Biomarin Pharmaceutical Inc.	Methods of treating phenylketonuria
TW202005978A (zh)	2018-05-14	2020-02-01	美商拜奧馬林製藥公司	新穎肝靶向腺相關病毒載體
CN110872293A (zh) *	2018-09-04	2020-03-10	北京启慧生物医药有限公司	一种生物蝶呤的化学合成及纯化方法
TW202144575A (zh)	2020-04-03	2021-12-01	美商拜奧馬林製藥公司	使用ａａｖ及治療調配物之苯酮尿症治療
CN111505179B (zh) *	2020-04-07	2021-07-13	厦门大学	海洋水体中生物蝶呤的检测方法
CN114814063A (zh) *	2022-04-08	2022-07-29	宁波熙宁检测技术有限公司	一种检测人体内四氢生物蝶呤的方法
GB202307239D0 (en)	2023-05-15	2023-06-28	Evox Therapeutics Ltd	Gene therapies for Phenylketonuria

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JP2674707B2 (ja)	1988-06-22	1997-11-12	株式会社ビタミン研究所	Ｌ‐ビオプテリンの製法
JP2575781B2 (ja)	1988-02-29	1997-01-29	日清製粉株式会社	２，３−ジアシルオキシ−４−ヒドロキシ−トペンタナールおよびその製造方法
JPH0231720A (ja)	1988-07-22	1990-02-01	Mitsubishi Electric Corp	自動製パン器
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US5184622A (en) *	1990-01-24	1993-02-09	Kabushiki Kaisha Toshiba	Ultrasonic diagnosing apparatus
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US5198547A (en) *	1992-03-16	1993-03-30	South Alabama Medical Science Foundation, Usa	Process for N5-formylating tetrahydropteridines
ZA939517B (en)	1992-12-23	1995-01-31	Smithkline Beecham Corp	Process
DE4308739C1 (de) *	1993-03-19	1994-06-23	Henning Berlin Gmbh	Pterinderivate, ihre Herstellung und ihre Verwendung
JP2711828B2 (ja)	1996-06-25	1998-02-10	白鳥製薬株式会社	（６ｒ）−テトラヒドローｌ−バイオプテリン塩酸塩の製造法
JP2001302665A (ja)	2000-04-19	2001-10-31	Shiratori Pharmaceutical Co Ltd	Ｌ−ビオプテリン又はｄ−ネオプテリンの製造法
US6544994B2 (en) *	2000-06-07	2003-04-08	Eprov Ag	Pharmaceutical preparation for treating or preventing cardiovascular or neurological disorders by modulating of the activity of nitric oxide synthase
BR0113411A (pt)	2000-08-31	2004-01-06	Daiichi Suntory Pharma Co Ltd	Processo para a produção do composto de biopterina
DE10260263A1 (de) *	2002-12-20	2004-07-15	Biocrates Life Sciences Gmbh	Verwendung von Tetrahydrobiopterinderivaten zur Behandlung und Ernährung von Patienten mit Aminosäurestoffwechselstörungen
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US7361759B2 (en) *	2004-12-27	2008-04-22	Shiratori Pharmaceutical Co., Ltd	Method for producing L-biopterin
US20060194808A1 (en) *	2005-01-14	2006-08-31	Chronorx Llc, An Alaska Limited Liability Company	Clinical applications of tetrahydrobiopterin, lipoic acid and their salts and methods of preparing tetrahydrobiopterin bis-lipoate
BRPI0608863B1 (pt)	2005-04-14	2022-09-27	Shiratori Pharmaceutical Co., Ltd.	Método para produzir cristais de cloridrato de sapropterina na forma alfa
AU2006241673B2 (en)	2005-04-28	2011-02-24	Daiichi Sankyo Company, Limited	Method for producing hydrazone derivatives
CA2675134A1 (en)	2007-01-12	2008-07-24	Biomarin Pharmaceutical Inc.	Pterin analogs

2009
- 2009-01-06 JP JP2010541558A patent/JP2011508781A/ja active Pending
- 2009-01-06 US US12/349,479 patent/US8178670B2/en active Active
- 2009-01-06 AR ARP090100026A patent/AR070109A1/es not_active Application Discontinuation
- 2009-01-06 AU AU2009204476A patent/AU2009204476A1/en not_active Abandoned
- 2009-01-06 CN CN2009801079643A patent/CN101959891A/zh active Pending
- 2009-01-06 BR BRPI0907247-0A patent/BRPI0907247A2/pt not_active IP Right Cessation
- 2009-01-06 TW TW098100222A patent/TW200942542A/zh unknown
- 2009-01-06 WO PCT/US2009/000030 patent/WO2009088979A1/en not_active Ceased
- 2009-01-06 RU RU2010133160/04A patent/RU2010133160A/ru not_active Application Discontinuation
- 2009-01-06 PE PE2009000007A patent/PE20091314A1/es not_active Application Discontinuation
- 2009-01-06 MX MX2010007452A patent/MX2010007452A/es active IP Right Grant
- 2009-01-06 EP EP09700703A patent/EP2240484A1/en not_active Withdrawn
- 2009-01-06 KR KR1020107017494A patent/KR20100101006A/ko not_active Withdrawn
- 2009-01-06 CA CA2711444A patent/CA2711444C/en active Active
- 2009-01-06 CL CL2009000007A patent/CL2009000007A1/es unknown
2010
- 2010-07-06 IL IL206845A patent/IL206845A0/en unknown
2011
- 2011-01-27 CL CL2011000166A patent/CL2011000166A1/es unknown

Also Published As

Publication number	Publication date
CL2009000007A1 (es)	2010-02-19
WO2009088979A1 (en)	2009-07-16
PE20091314A1 (es)	2009-09-03
EP2240484A1 (en)	2010-10-20
TW200942542A (en)	2009-10-16
AR070109A1 (es)	2010-03-17
US20090198055A1 (en)	2009-08-06
CA2711444A1 (en)	2009-07-16
CN101959891A (zh)	2011-01-26
KR20100101006A (ko)	2010-09-15
IL206845A0 (en)	2010-12-30
CL2011000166A1 (es)	2011-07-01
AU2009204476A1 (en)	2009-07-16
CA2711444C (en)	2017-12-12
US8178670B2 (en)	2012-05-15
MX2010007452A (es)	2010-08-18
RU2010133160A (ru)	2012-02-20
JP2011508781A (ja)	2011-03-17

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Legal Events

Date	Code	Title	Description
2015-08-25	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A E 6A ANUIDADES.
2016-05-10	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.