BRPI0818545A2 - formulações de vacinais meningocócicas - Google Patents
formulações de vacinais meningocócicasInfo
- Publication number
- BRPI0818545A2 BRPI0818545A2 BRPI0818545A BRPI0818545A BRPI0818545A2 BR PI0818545 A2 BRPI0818545 A2 BR PI0818545A2 BR PI0818545 A BRPI0818545 A BR PI0818545A BR PI0818545 A BRPI0818545 A BR PI0818545A BR PI0818545 A2 BRPI0818545 A2 BR PI0818545A2
- Authority
- BR
- Brazil
- Prior art keywords
- meningitidis
- vaccine formulations
- lyophilised
- meningococcal vaccine
- formulation
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 229940124731 meningococcal vaccine Drugs 0.000 title 1
- 241000588650 Neisseria meningitidis Species 0.000 abstract 2
- 241000588677 Neisseria meningitidis serogroup B Species 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000007764 o/w emulsion Substances 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR122016015627A BR122016015627A2 (pt) | 2007-10-19 | 2008-10-17 | kit, composição antigênica liofilizada e método para preparação de uma composição imunogênica |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99959007P | 2007-10-19 | 2007-10-19 | |
| PCT/IB2008/003283 WO2009050586A1 (en) | 2007-10-19 | 2008-10-17 | Meningococcal vaccine formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0818545A2 true BRPI0818545A2 (pt) | 2017-07-04 |
Family
ID=40428348
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR122016015627A BR122016015627A2 (pt) | 2007-10-19 | 2008-10-17 | kit, composição antigênica liofilizada e método para preparação de uma composição imunogênica |
| BRPI0818545A BRPI0818545A2 (pt) | 2007-10-19 | 2008-10-17 | formulações de vacinais meningocócicas |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR122016015627A BR122016015627A2 (pt) | 2007-10-19 | 2008-10-17 | kit, composição antigênica liofilizada e método para preparação de uma composição imunogênica |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20100285069A1 (pt) |
| EP (2) | EP2462949A3 (pt) |
| JP (3) | JP5701058B2 (pt) |
| CN (1) | CN101951949B (pt) |
| AT (1) | ATE553774T1 (pt) |
| AU (1) | AU2008313424B2 (pt) |
| BR (2) | BR122016015627A2 (pt) |
| CA (2) | CA2702871A1 (pt) |
| CO (1) | CO6270339A2 (pt) |
| CY (1) | CY1112908T1 (pt) |
| DK (1) | DK2200642T3 (pt) |
| ES (1) | ES2383231T3 (pt) |
| HR (1) | HRP20120433T1 (pt) |
| MX (2) | MX2010004271A (pt) |
| NZ (1) | NZ584683A (pt) |
| PL (1) | PL2200642T3 (pt) |
| PT (1) | PT2200642E (pt) |
| RU (2) | RU2498815C2 (pt) |
| SI (1) | SI2200642T1 (pt) |
| WO (1) | WO2009050586A1 (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| RU2009149359A (ru) * | 2007-06-04 | 2011-07-20 | Новартис АГ (CH) | Состав вакцин против менингита |
| US20100189737A1 (en) * | 2008-12-17 | 2010-07-29 | Arico Beatrice | Meningococcal vaccines including hemoglobin receptor |
| WO2011027222A2 (en) | 2009-09-02 | 2011-03-10 | Novartis Ag | Immunogenic compositions including tlr activity modulators |
| PT2608805T (pt) * | 2010-08-23 | 2017-09-11 | Wyeth Llc | Formulações estáveis de antigénios de rlp2086 de neisseria meningitidis |
| EP2719395A1 (en) | 2010-09-01 | 2014-04-16 | Novartis AG | Adsorption of immunopotentiators to insoluble metal salts |
| CN103096920B (zh) | 2010-09-10 | 2016-03-23 | 惠氏有限责任公司 | 脑膜炎奈瑟球菌orf2086抗原的非脂质化变体 |
| WO2012117377A1 (en) | 2011-03-02 | 2012-09-07 | Novartis Ag | Combination vaccines with lower doses of antigen and/or adjuvant |
| IN2012MU00206A (pt) * | 2012-01-20 | 2013-08-09 | ||
| ES2597755T3 (es) | 2012-03-07 | 2017-01-20 | Glaxosmithkline Biologicals Sa | Sales de arginina de un agonista de TLR7 |
| CA2866406A1 (en) | 2012-03-08 | 2013-09-12 | Novartis Ag | Adjuvanted formulations of booster vaccines |
| JP5925342B2 (ja) | 2012-03-09 | 2016-05-25 | ファイザー・インク | 髄膜炎菌(Neisseriameningitidis)組成物およびその方法 |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| CA2875391A1 (en) | 2012-07-27 | 2014-01-30 | Institut National De La Sante Et De La Recherche Medicale | Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia |
| ES2685894T3 (es) | 2013-03-08 | 2018-10-15 | Pfizer Inc. | Polipéptidos de fusión inmunogénicos |
| CA2923129C (en) | 2013-09-08 | 2020-06-09 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| KR20170103009A (ko) | 2015-02-19 | 2017-09-12 | 화이자 인코포레이티드 | 나이세리아 메닌지티디스 조성물 및 그의 방법 |
| HRP20240433T1 (hr) | 2016-09-02 | 2024-07-05 | Sanofi Pasteur, Inc. | Cjepivo protiv neisseria meningitidis |
| IL303108B2 (en) | 2017-01-31 | 2024-07-01 | Pfizer | NEISSERIA MENINGITIDIS preparations and methods therefor |
| CN111278458A (zh) * | 2017-10-25 | 2020-06-12 | 默沙东公司 | 佐剂疫苗 |
| EP4034157A1 (en) | 2019-09-27 | 2022-08-03 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
Family Cites Families (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4057685A (en) | 1972-02-02 | 1977-11-08 | Abbott Laboratories | Chemically modified endotoxin immunizing agent |
| DE2848965A1 (de) | 1978-11-11 | 1980-05-22 | Behringwerke Ag | Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine |
| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US4459286A (en) | 1983-01-31 | 1984-07-10 | Merck & Co., Inc. | Coupled H. influenzae type B vaccine |
| US4663160A (en) | 1983-03-14 | 1987-05-05 | Miles Laboratories, Inc. | Vaccines for gram-negative bacteria |
| US4761283A (en) | 1983-07-05 | 1988-08-02 | The University Of Rochester | Immunogenic conjugates |
| US4808700A (en) | 1984-07-09 | 1989-02-28 | Praxis Biologics, Inc. | Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers |
| IT1187753B (it) | 1985-07-05 | 1987-12-23 | Sclavo Spa | Coniugati glicoproteici ad attivita' immunogenica trivalente |
| US4803070A (en) * | 1986-04-15 | 1989-02-07 | Ribi Immunochem Research Inc. | Immunological emulsion adjuvants for polysaccharide vaccines |
| US5204098A (en) | 1988-02-16 | 1993-04-20 | The United States Of America As Represented By The Department Of Health And Human Services | Polysaccharide-protein conjugates |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| NL8802046A (nl) | 1988-08-18 | 1990-03-16 | Gen Electric | Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen. |
| DE3841091A1 (de) | 1988-12-07 | 1990-06-13 | Behringwerke Ag | Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung |
| CA2006700A1 (en) | 1989-01-17 | 1990-07-17 | Antonello Pessi | Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines |
| HU212924B (en) | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| FI920131A7 (fi) | 1989-07-14 | 1992-01-13 | American Cyanamid Co | Sytokiini- ja hormonikantajia konjugaattirokotteita varten |
| IT1237764B (it) | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
| SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
| DE69113564T2 (de) | 1990-08-13 | 1996-05-30 | American Cyanamid Co | Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff. |
| IL101007A (en) | 1992-02-18 | 1997-08-14 | Pharmos Ltd | Dry stable compositions prepared by lyophilization |
| IT1262896B (it) | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
| IL102687A (en) | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
| US5425946A (en) | 1992-08-31 | 1995-06-20 | North American Vaccine, Inc. | Vaccines against group C Neisseria meningitidis |
| WO1994005325A1 (en) | 1992-08-31 | 1994-03-17 | North American Vaccine, Inc. | Vaccines against group c neisseria meningitidis |
| AU5543294A (en) | 1993-10-29 | 1995-05-22 | Pharmos Corp. | Submicron emulsions as vaccine adjuvants |
| GB9422096D0 (en) * | 1994-11-02 | 1994-12-21 | Biocine Spa | Combined meningitis vaccine |
| IL117483A (en) | 1995-03-17 | 2008-03-20 | Bernard Brodeur | MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K. |
| US6180111B1 (en) | 1995-05-18 | 2001-01-30 | University Of Maryland | Vaccine delivery system |
| US6080725A (en) | 1997-05-20 | 2000-06-27 | Galenica Pharmaceuticals, Inc. | Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof |
| AU7701098A (en) | 1997-05-28 | 1998-12-30 | Michael A. Apicella | Laft mutants of pathogenic gram-negative bacteria |
| GB9711964D0 (en) | 1997-06-09 | 1997-08-06 | Medical Res Council | Live attenuated vaccines |
| GB9713156D0 (en) | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
| US7011836B1 (en) | 1997-08-21 | 2006-03-14 | De Staat Der Nederlanden, Vertenwoordigd Door De Minister Van Welzijn, Volksgezondheil En Cultuur | Mutants of gram negative mucosal bacteria and application thereof in vaccines |
| WO1999024578A2 (en) | 1997-11-06 | 1999-05-20 | Chiron S.P.A. | Neisserial antigens |
| CN1224708C (zh) | 1998-01-14 | 2005-10-26 | 启龙股份公司 | 脑膜炎奈瑟氏球菌抗原 |
| DK1584685T3 (da) * | 1998-02-05 | 2011-07-11 | Glaxosmithkline Biolog Sa | Tumorassocieret antigenderivater fra Mage-familien, anvendt til fremstilling af fusionsproteiner med T-hjælper epitoper og sammensætninger til vaccination |
| US7018637B2 (en) | 1998-02-23 | 2006-03-28 | Aventis Pasteur, Inc | Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines |
| US6645503B1 (en) | 1998-03-10 | 2003-11-11 | Wyeth Holdings Corporation | Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria |
| EP2261350A3 (en) | 1998-05-01 | 2012-01-04 | Novartis Vaccines and Diagnostics, Inc. | Neisseria meningitidis antigens and compositions |
| EP1741443B1 (en) * | 1998-05-29 | 2014-05-21 | Novartis Vaccines and Diagnostics, Inc. | Combination meningitidis B/C vaccines |
| JP5074644B2 (ja) * | 1998-05-29 | 2012-11-14 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 組合わせの髄膜炎菌b/cワクチン |
| CN1263510C (zh) | 1998-08-19 | 2006-07-12 | 巴克斯特健康护理股份有限公司 | 多糖-蛋白质缀合物或寡糖-蛋白质缀合物、其制备方法及其应用 |
| EP1559795A3 (en) | 1998-10-09 | 2005-11-09 | Chiron Corporation | Neisseria genomic sequences and methods of their use |
| GB9823978D0 (en) | 1998-11-02 | 1998-12-30 | Microbiological Res Authority | Multicomponent meningococcal vaccine |
| WO2000026384A1 (en) | 1998-11-03 | 2000-05-11 | De Staat Der Nederlanden, Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur | Lps with reduced toxicity from genetically modified gram negative bacteria |
| AU1626199A (en) | 1998-12-04 | 2000-06-26 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | A vi-repa conjugate vaccine for immunization against salmonella typhi |
| HU229968B1 (hu) | 1999-03-19 | 2015-03-30 | Smithkline Beecham Biologicals S.A | Sztreptokokkusz oltóanyag |
| WO2000061761A2 (en) | 1999-04-09 | 2000-10-19 | Techlab, Inc. | Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines |
| GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| US6531131B1 (en) | 1999-08-10 | 2003-03-11 | The United States Of America As Represented By The Department Of Health And Human Services | Conjugate vaccine for Neisseria meningitidis |
| GB9925559D0 (en) | 1999-10-28 | 1999-12-29 | Smithkline Beecham Biolog | Novel method |
| AU1917501A (en) | 1999-11-12 | 2001-06-06 | University Of Iowa Research Foundation, The | Control of neisserial membrane synthesis |
| BR0107679A (pt) | 2000-01-17 | 2004-07-06 | Chiron Spa | Vacina de vesìcula de membrana externa (omv) compreendendo proteìnas de membrana externa do grupo sérico b de neisseria meningitidis |
| AU2001239488B2 (en) | 2000-02-28 | 2006-01-19 | Glaxosmithkline Biologicals S.A. | Heterologous expression of neisserial proteins |
| GB0007432D0 (en) | 2000-03-27 | 2000-05-17 | Microbiological Res Authority | Proteins for use as carriers in conjugate vaccines |
| NO20002828D0 (no) | 2000-06-02 | 2000-06-02 | Statens Inst For Folkehelse | Proteinholdig vaksine mot Neisseria meningtidis serogruppe samt fremgangsmÕte ved fremstilling derav |
| AU2001280883A1 (en) | 2000-07-27 | 2002-02-13 | The Children's Hospital & Research Center At Oakland | Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis |
| GB0103170D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| AP1897A (en) | 2001-01-23 | 2008-10-10 | Aventis Pasteur | Multivalent Meningococcal polysaccharide-Protein Conjugate Vaccine. |
| GB0103171D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| AU2002309706A1 (en) | 2001-05-11 | 2002-11-25 | Aventis Pasteur, Inc. | Novel meningitis conjugate vaccine |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| WO2003080678A1 (en) | 2002-03-26 | 2003-10-02 | Chiron Srl | Modified saccharides having improved stability in water |
| GB0302218D0 (en) * | 2003-01-30 | 2003-03-05 | Chiron Sri | Vaccine formulation & Mucosal delivery |
| GB0213622D0 (en) | 2002-06-13 | 2002-07-24 | Glaxosmithkline Biolog Sa | Vaccine Corporation |
| JP4740738B2 (ja) | 2002-08-02 | 2011-08-03 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
| GB0218821D0 (en) * | 2002-08-13 | 2002-09-18 | Glaxosmithkline Biolog Sa | Novel compositions |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| US20060110736A1 (en) * | 2002-10-07 | 2006-05-25 | John Donnelly | Hiv vaccine formulations |
| DE60335477D1 (de) | 2002-10-11 | 2011-02-03 | Novartis Vaccines & Diagnostic | Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien |
| EP2279746B1 (en) * | 2002-11-15 | 2013-10-02 | Novartis Vaccines and Diagnostics S.r.l. | Surface proteins in neisseria meningitidis |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| EP2191844B1 (en) * | 2003-01-30 | 2014-03-05 | Novartis AG | Injectable vaccines against multiple meningococcal serogroups |
| EP1608403A2 (en) * | 2003-04-02 | 2005-12-28 | Coley Pharmaceutical Group, Ltd. | Immunostimulatory nucleic acid oil-in-water formulations for topical application |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| CA2885040C (en) * | 2003-10-02 | 2018-10-30 | Novartis Vaccines And Diagnostics S.R.L. | Liquid vaccines for multiple meningococcal serogroups |
| GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| JP5173194B2 (ja) * | 2003-12-23 | 2013-03-27 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
| CN1997390B (zh) | 2004-04-05 | 2012-10-10 | 辉瑞产品有限公司 | 微流化水包油乳状液和疫苗组合物 |
| GB0409745D0 (en) * | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
| GB0419627D0 (en) | 2004-09-03 | 2004-10-06 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| ES2434029T3 (es) * | 2004-11-15 | 2013-12-13 | Novartis Vaccines And Diagnostics, Inc. | Composiciones inmunogénicas que contiene antígeno de antrax, micropartículas de polímero biodegradable, y adyuvante inmunológico que contiene polinucleótido |
| EP2682126B1 (en) | 2005-01-27 | 2016-11-23 | Children's Hospital & Research Center at Oakland | GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis |
| AU2006226459A1 (en) | 2005-03-23 | 2006-09-28 | Glaxosmithkline Biologicals S.A. | Composition |
| US20060228369A1 (en) | 2005-04-11 | 2006-10-12 | Program For Appropriate Technology In Health | Stabilization and preservation of temperature-sensitive vaccines |
| US7691368B2 (en) | 2005-04-15 | 2010-04-06 | Merial Limited | Vaccine formulations |
| US8156755B2 (en) * | 2005-06-03 | 2012-04-17 | Intervet International B.V. | Refrigerator for storing vials and cartridge for use in the same |
| KR101408113B1 (ko) | 2005-06-27 | 2014-06-16 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 백신 제조 방법 |
| US8703095B2 (en) | 2005-07-07 | 2014-04-22 | Sanofi Pasteur S.A. | Immuno-adjuvant emulsion |
| EA014107B1 (ru) | 2005-12-22 | 2010-10-29 | Глаксосмитклайн Байолоджикалс С.А. | Вакцина, содержащая конъюгаты капсульных полисахаридов streptococcus pneumoniae |
| US8431160B2 (en) * | 2006-02-24 | 2013-04-30 | Novartis Ag | Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions |
| GB0700135D0 (en) * | 2007-01-04 | 2007-02-14 | Glaxosmithkline Biolog Sa | Vaccine |
| RU2009149359A (ru) * | 2007-06-04 | 2011-07-20 | Новартис АГ (CH) | Состав вакцин против менингита |
-
2008
- 2008-10-17 AT AT08838605T patent/ATE553774T1/de active
- 2008-10-17 EP EP12158035A patent/EP2462949A3/en not_active Withdrawn
- 2008-10-17 CN CN2008801213328A patent/CN101951949B/zh not_active Expired - Fee Related
- 2008-10-17 ES ES08838605T patent/ES2383231T3/es active Active
- 2008-10-17 MX MX2010004271A patent/MX2010004271A/es active IP Right Grant
- 2008-10-17 PT PT08838605T patent/PT2200642E/pt unknown
- 2008-10-17 RU RU2010119947/10A patent/RU2498815C2/ru not_active IP Right Cessation
- 2008-10-17 PL PL08838605T patent/PL2200642T3/pl unknown
- 2008-10-17 US US12/734,185 patent/US20100285069A1/en not_active Abandoned
- 2008-10-17 SI SI200830631T patent/SI2200642T1/sl unknown
- 2008-10-17 JP JP2010529472A patent/JP5701058B2/ja not_active Expired - Fee Related
- 2008-10-17 BR BR122016015627A patent/BR122016015627A2/pt not_active Application Discontinuation
- 2008-10-17 DK DK08838605.7T patent/DK2200642T3/da active
- 2008-10-17 AU AU2008313424A patent/AU2008313424B2/en not_active Ceased
- 2008-10-17 CA CA2702871A patent/CA2702871A1/en not_active Abandoned
- 2008-10-17 HR HRP20120433AT patent/HRP20120433T1/xx unknown
- 2008-10-17 BR BRPI0818545A patent/BRPI0818545A2/pt not_active IP Right Cessation
- 2008-10-17 NZ NZ584683A patent/NZ584683A/en not_active IP Right Cessation
- 2008-10-17 CA CA2925217A patent/CA2925217A1/en not_active Abandoned
- 2008-10-17 MX MX2012007222A patent/MX340096B/es unknown
- 2008-10-17 WO PCT/IB2008/003283 patent/WO2009050586A1/en not_active Ceased
- 2008-10-17 EP EP08838605A patent/EP2200642B1/en not_active Not-in-force
-
2010
- 2010-05-04 CO CO10052816A patent/CO6270339A2/es not_active Application Discontinuation
-
2012
- 2012-07-12 CY CY20121100625T patent/CY1112908T1/el unknown
-
2013
- 2013-07-19 RU RU2013133864/10A patent/RU2013133864A/ru not_active Application Discontinuation
- 2013-07-30 JP JP2013157634A patent/JP5925736B2/ja not_active Expired - Fee Related
-
2015
- 2015-11-19 JP JP2015226282A patent/JP2016029108A/ja not_active Withdrawn
-
2016
- 2016-01-29 US US15/011,216 patent/US20160228529A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0818545A2 (pt) | formulações de vacinais meningocócicas | |
| MX348734B (es) | Vacunacion multiple que incluye meningococcus del serogrupo c. | |
| RU2378009C2 (ru) | Иммунизация против менингококков серогруппы y с помощью белков | |
| CR10123A (es) | Vacuna. | |
| MXPA05007886A (es) | Vacunas para la mucosa con adyuvante de quitosan y antigenos para meningococo. | |
| CY1110140T1 (el) | Εμβολιασμος με μηνιγγοκοκκικο συζευγμα | |
| CY1111814T1 (el) | Ενσωματωση του εμβολιασμου μηνιγγιτιδοκοκκικων συζευματων | |
| Centers for Disease Control and Prevention (CDC | Guillain-Barré syndrome among recipients of Menactra meningococcal conjugate vaccine--United States, June-July 2005 | |
| DK1755662T3 (da) | Kombinerede meningokokkonjugater med fælles bærerprotein | |
| Sanders et al. | Adjuvant properties of meningococcal outer membrane vesicles and the use of adjuvants in Neisseria meningitidis protein vaccines | |
| WO2010067202A3 (en) | Mixing lyophilised meningococcal vaccines with non-hib vaccines | |
| WO2018042017A3 (en) | Vaccines for neisseria gonorrhoeae | |
| MX2015013401A (es) | Procedimiento de tratamiento. | |
| Haneberg et al. | Can nonliving nasal vaccines be made to work? | |
| WO2005023295A3 (en) | Naturally processed immunodominant peptides derived from neisseria meningitidis porin a protein and their use | |
| AR095579A1 (es) | Procedimiento de inmunización |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |