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MX2010004271A - Formulaciones de vacuna meningococica. - Google Patents

Formulaciones de vacuna meningococica.

Info

Publication number
MX2010004271A
MX2010004271A MX2010004271A MX2010004271A MX2010004271A MX 2010004271 A MX2010004271 A MX 2010004271A MX 2010004271 A MX2010004271 A MX 2010004271A MX 2010004271 A MX2010004271 A MX 2010004271A MX 2010004271 A MX2010004271 A MX 2010004271A
Authority
MX
Mexico
Prior art keywords
men
lyophilised
vaccine formulations
formulation
meningococcal vaccine
Prior art date
Application number
MX2010004271A
Other languages
English (en)
Inventor
Mario Contorni
Manmohan Singh
Jina Kazzaz
Derek O'hagan
Mildred Ugozzoli
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2010004271A publication Critical patent/MX2010004271A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Una formulación dual para vacunas contra el serogrupo B de Neisseria meningitidis ("Men-B") comprende (i) un adyuvante de emulsión de aceite en agua y (ii) un componente inmunogénico de Men-B en forma liofilizada. Los antígenos liofilizados de Men-B se pueden reconstituir en forma líquida con adyuvante en el momento de uso listo para administración a un paciente. Se ha encontrado que esta formulación da excelentes resultados en términos tanto de estabilidad como de inmunogenicidad. El componente liofilizado también puede incluir uno o más sacáridos conjugados de los serogrupos A, C, W135 y/o Y de N. meningitidis.
MX2010004271A 2007-10-19 2008-10-17 Formulaciones de vacuna meningococica. MX2010004271A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99959007P 2007-10-19 2007-10-19
PCT/IB2008/003283 WO2009050586A1 (en) 2007-10-19 2008-10-17 Meningococcal vaccine formulations

Publications (1)

Publication Number Publication Date
MX2010004271A true MX2010004271A (es) 2010-05-03

Family

ID=40428348

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2010004271A MX2010004271A (es) 2007-10-19 2008-10-17 Formulaciones de vacuna meningococica.
MX2012007222A MX340096B (es) 2007-10-19 2008-10-17 Formulaciones de vacuna meningococica.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2012007222A MX340096B (es) 2007-10-19 2008-10-17 Formulaciones de vacuna meningococica.

Country Status (20)

Country Link
US (2) US20100285069A1 (es)
EP (2) EP2462949A3 (es)
JP (3) JP5701058B2 (es)
CN (1) CN101951949B (es)
AT (1) ATE553774T1 (es)
AU (1) AU2008313424B2 (es)
BR (2) BR122016015627A2 (es)
CA (2) CA2702871A1 (es)
CO (1) CO6270339A2 (es)
CY (1) CY1112908T1 (es)
DK (1) DK2200642T3 (es)
ES (1) ES2383231T3 (es)
HR (1) HRP20120433T1 (es)
MX (2) MX2010004271A (es)
NZ (1) NZ584683A (es)
PL (1) PL2200642T3 (es)
PT (1) PT2200642E (es)
RU (2) RU2498815C2 (es)
SI (1) SI2200642T1 (es)
WO (1) WO2009050586A1 (es)

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WO2012117377A1 (en) 2011-03-02 2012-09-07 Novartis Ag Combination vaccines with lower doses of antigen and/or adjuvant
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CA2866406A1 (en) 2012-03-08 2013-09-12 Novartis Ag Adjuvanted formulations of booster vaccines
JP5925342B2 (ja) 2012-03-09 2016-05-25 ファイザー・インク 髄膜炎菌（Ｎｅｉｓｓｅｒｉａｍｅｎｉｎｇｉｔｉｄｉｓ）組成物およびその方法
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Also Published As

Publication number Publication date
PT2200642E (pt) 2012-05-30
PL2200642T3 (pl) 2012-09-28
RU2013133864A (ru) 2015-01-27
AU2008313424A1 (en) 2009-04-23
AU2008313424B2 (en) 2014-05-22
ES2383231T3 (es) 2012-06-19
CY1112908T1 (el) 2016-04-13
JP2011500662A (ja) 2011-01-06
NZ584683A (en) 2012-05-25
SI2200642T1 (sl) 2012-06-29
JP2013216704A (ja) 2013-10-24
CO6270339A2 (es) 2011-04-20
DK2200642T3 (da) 2012-07-16
US20100285069A1 (en) 2010-11-11
JP2016029108A (ja) 2016-03-03
ATE553774T1 (de) 2012-05-15
EP2200642A1 (en) 2010-06-30
BR122016015627A2 (pt) 2018-10-30
CA2925217A1 (en) 2009-04-23
MX340096B (es) 2016-06-27
WO2009050586A1 (en) 2009-04-23
CN101951949B (zh) 2013-10-02
EP2200642B1 (en) 2012-04-18
CA2702871A1 (en) 2009-04-23
BRPI0818545A2 (pt) 2017-07-04
RU2498815C2 (ru) 2013-11-20
CN101951949A (zh) 2011-01-19
HRP20120433T1 (en) 2012-07-31
JP5701058B2 (ja) 2015-04-15
EP2462949A3 (en) 2012-09-05
US20160228529A1 (en) 2016-08-11
RU2010119947A (ru) 2011-11-27
JP5925736B2 (ja) 2016-05-25
EP2462949A2 (en) 2012-06-13

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