BRPI0815918A2 - Processos de purificação de fviii ou de fvw a partir de uma solução e de obtenção de um fviii purificado e de um fvw purificado. - Google Patents

Processos de purificação de fviii ou de fvw a partir de uma solução e de obtenção de um fviii purificado e de um fvw purificado.

Info

Publication number: BRPI0815918A2
Authority: BR; Brazil
Prior art keywords: fviii; vwf; purified; obtaining; solution
Prior art date: 2007-08-30

Application number

BRPI0815918-1A2A

Other languages

English (en)

Inventor

Michel Poulle

Patrick Bonneel

Original Assignee

Lfb Biotechnologies

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-30

Filing date

2008-08-28

Publication date

2015-02-18

2008-08-28 Application filed by Lfb Biotechnologies filed Critical Lfb Biotechnologies

2015-02-18 Publication of BRPI0815918A2 publication Critical patent/BRPI0815918A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Analytical Chemistry (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BRPI0815918-1A2A 2007-08-30 2008-08-28 Processos de purificação de fviii ou de fvw a partir de uma solução e de obtenção de um fviii purificado e de um fvw purificado. BRPI0815918A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0757266A FR2920429B1 (fr)	2007-08-30	2007-08-30	Procede de purification du facteur viii et du facteur von willebrand
PCT/FR2008/051543 WO2009030866A2 (fr)	2007-08-30	2008-08-28	Procede de purification du facteur viii et du facteur von willebrand

Publications (1)

Publication Number	Publication Date
BRPI0815918A2 true BRPI0815918A2 (pt)	2015-02-18

Family

ID=39463904

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0815918-1A2A BRPI0815918A2 (pt)	2007-08-30	2008-08-28	Processos de purificação de fviii ou de fvw a partir de uma solução e de obtenção de um fviii purificado e de um fvw purificado.

Country Status (12)

Country	Link
US (1)	US20100305305A1 (pt)
EP (1)	EP2183269A2 (pt)
JP (2)	JP5704918B2 (pt)
KR (1)	KR20100058520A (pt)
CN (1)	CN101796065A (pt)
AR (1)	AR068132A1 (pt)
AU (1)	AU2008294610A1 (pt)
BR (1)	BRPI0815918A2 (pt)
CA (1)	CA2697404A1 (pt)
FR (1)	FR2920429B1 (pt)
TW (1)	TW200918145A (pt)
WO (1)	WO2009030866A2 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2920429B1 (fr) *	2007-08-30	2012-10-05	Lfb Biotechnologies	Procede de purification du facteur viii et du facteur von willebrand
ES2887187T3 (es) *	2007-12-28	2021-12-22	Takeda Pharmaceuticals Co	Formulaciones de VWF recombinante
US11197916B2 (en)	2007-12-28	2021-12-14	Takeda Pharmaceutical Company Limited	Lyophilized recombinant VWF formulations
FR2933496B1 (fr) *	2008-07-02	2012-10-05	Lfb Biotechnologies	Procede de mesure du taux de facteur vii active dans un echantillon
KR101772674B1 (ko)	2008-10-21	2017-09-01	박스알타 인코퍼레이티드	동결건조된 재조합 ｖｗｆ 제제
TWI546382B (zh)	2010-04-30	2016-08-21	Asahi Kasei Pharma Corp	High purity soluble thrombin modulator and its manufacturing method
AU2011343813B2 (en) *	2010-12-15	2015-05-21	Takeda Pharmaceutical Company Limited	Eluate collection using conductivity gradient
JP2015515482A (ja) *	2012-04-24	2015-05-28	ノヴォノルディスクアー／エス	血友病の治療に適する化合物
US20140154233A1 (en) *	2012-12-05	2014-06-05	Csl Limited	Method of purifying therapeutic proteins
ES2693380T3 (es) *	2013-11-08	2018-12-11	Csl Limited	Nuevo método para concentrar el factor de von Willebrand o complejos de este
US10822393B2 (en) *	2014-01-20	2020-11-03	Octapharma Ag	Process for manufacturing factor VIII having an improved ratio of FVIII:C/FVIII/AG
GB201506117D0 (en) *	2015-04-10	2015-05-27	Ge Healthcare Bio Sciences Ab	Method for chromatography
GB201506113D0 (en) *	2015-04-10	2015-05-27	Ge Healthcare Bio Sciences Ab	Method for chromatography
CN111491949B (zh) *	2017-10-27	2024-01-09	株式会社绿十字控股	用于制备具有血管性血友病因子(vwf)受控含量的含有因子viii(fviii)和血管性血友病因子的组合物的方法
EP3781940B1 (en) *	2018-04-19	2024-05-29	Waters Technologies Corporation	Filtration device for chromatographic instruments
CN109705208B (zh) *	2018-12-29	2022-04-26	山东泰邦生物制品有限公司	一种单步层析制备高纯度血管性血友病因子的工艺

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5198349A (en) *	1986-01-03	1993-03-30	Genetics Institute, Inc.	Method for producing factor VIII:C and analogs
FR2632309B1 (fr) *	1988-06-07	1990-08-24	Lille Transfusion Sanguine	Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
FR2673632A1 (fr) *	1991-03-08	1992-09-11	Lille Transfusion Sanguine	Procede de preparation de concentre de facteur von willebrand humain de tres haute purete, approprie a un usage therapeutique.
US5693506A (en) *	1993-11-16	1997-12-02	The Regents Of The University Of California	Process for protein production in plants
US5880327A (en) *	1994-09-21	1999-03-09	American National Red Cross	Transgenic mammals expressing human coagulation factor VIII
DE4435485C1 (de) *	1994-10-04	1996-03-21	Immuno Ag	Verfahren zur Gewinnung von hochreinem von Willebrand-Faktor
AT404358B (de) *	1997-02-04	1998-11-25	Immuno Ag	Verfahren zur chromatographischen reinigung bzw. fraktionierung von von willebrand-faktor aus einem vwf-hältigen ausgangsmaterial
AT406867B (de) *	1997-02-27	2000-10-25	Immuno Ag	Verfahren zur gewinnung von hochreinem vwf oder faktor viii/vwf-komplex
FR2772381B1 (fr) *	1997-12-15	2001-06-08	Lab Francais Du Fractionnement	Procede de preparation par filtration d'une solution de facteur viii securisee viralement
WO1999037680A1 (en) *	1998-01-23	1999-07-29	Csl Limited	Purification of fibrinogen
US20050060775A1 (en) *	1998-05-14	2005-03-17	Hooker Brian S.	Production of human coagulation factor VIII from plant cells and whole plants
US6331416B1 (en) *	1999-06-10	2001-12-18	Cbd Technologies Ltd.	Process of expressing and isolating recombinant proteins and recombinant protein products from plants, plant derived tissues or cultured plant cells
EP1148063A1 (de) *	2000-04-18	2001-10-24	Octapharma AG	Haemostatisch aktives vWF enthaltendes Präparat und Verfahren zu seiner Herstellung
AUPR110100A0 (en) *	2000-10-30	2000-11-23	Life Therapeutics Limited	Improved separation of macromolecules
FR2861395B1 (fr) *	2003-10-23	2006-02-17	Lab Francais Du Fractionnement	Facteur viii viralement securise a faible teneur en multimeres superieurs
DE102004009400A1 (de) *	2004-02-24	2005-09-08	Zlb Behring Gmbh	Fibrinogen Reinigung
FR2874216B1 (fr) *	2004-08-16	2006-11-03	Lab Francais Du Fractionnement	Procede de preparation d'un concentre de facteur von willebrand (fvw) par voie chromatographique et concentre de fvw susceptible d'etre ainsi obtenu
EP1807101B1 (en) *	2004-09-30	2016-04-13	Bayer Healthcare LLC	Devices and methods for integrated continuous manufacturing of biological molecules
US20070011752A1 (en) *	2005-05-06	2007-01-11	American Integrated Biologics, Inc.	Production of human proteins in transgenic animal saliva
WO2008057683A2 (en) *	2006-10-03	2008-05-15	Novo Nordisk A/S	Methods for the purification of polypeptide conjugates
FR2920429B1 (fr) *	2007-08-30	2012-10-05	Lfb Biotechnologies	Procede de purification du facteur viii et du facteur von willebrand

2007
- 2007-08-30 FR FR0757266A patent/FR2920429B1/fr not_active Expired - Fee Related
2008
- 2008-08-28 EP EP08829221A patent/EP2183269A2/fr not_active Withdrawn
- 2008-08-28 WO PCT/FR2008/051543 patent/WO2009030866A2/fr not_active Ceased
- 2008-08-28 CA CA2697404A patent/CA2697404A1/fr not_active Abandoned
- 2008-08-28 AU AU2008294610A patent/AU2008294610A1/en not_active Abandoned
- 2008-08-28 JP JP2010522422A patent/JP5704918B2/ja not_active Expired - Fee Related
- 2008-08-28 KR KR1020107004515A patent/KR20100058520A/ko not_active Ceased
- 2008-08-28 US US12/675,608 patent/US20100305305A1/en not_active Abandoned
- 2008-08-28 BR BRPI0815918-1A2A patent/BRPI0815918A2/pt not_active IP Right Cessation
- 2008-08-28 CN CN200880104709A patent/CN101796065A/zh active Pending
- 2008-08-29 AR ARP080103760A patent/AR068132A1/es unknown
- 2008-08-29 TW TW097133336A patent/TW200918145A/zh unknown
2014
- 2014-12-01 JP JP2014243079A patent/JP2015042687A/ja active Pending

Also Published As

Publication number	Publication date
US20100305305A1 (en)	2010-12-02
FR2920429A1 (fr)	2009-03-06
WO2009030866A2 (fr)	2009-03-12
AR068132A1 (es)	2009-11-04
KR20100058520A (ko)	2010-06-03
WO2009030866A3 (fr)	2009-05-07
EP2183269A2 (fr)	2010-05-12
TW200918145A (en)	2009-05-01
FR2920429B1 (fr)	2012-10-05
CN101796065A (zh)	2010-08-04
JP5704918B2 (ja)	2015-04-22
JP2010537960A (ja)	2010-12-09
CA2697404A1 (fr)	2009-03-12
JP2015042687A (ja)	2015-03-05
AU2008294610A1 (en)	2009-03-12

Publication	Publication Date	Title
BRPI0815918A2 (pt)	2015-02-18	Processos de purificação de fviii ou de fvw a partir de uma solução e de obtenção de um fviii purificado e de um fvw purificado.
FR2921499B1 (fr)	2009-11-13	Structure orientable de type catheter ou endoscope
EP2411973A4 (en)	2013-11-27	LIGHTING PANEL
EP2126962A4 (en)	2014-09-03	SEALED LIGHTING UNITS
EP2195270A4 (en)	2014-01-22	LIFT SYSTEM
BRPI0811678A2 (pt)	2015-02-10	"aparelho de iluminação"
ZA201008720B (en)	2012-02-29	Fviii muteins for treatment of von willebrand disease
BRPI0809866A2 (pt)	2014-11-11	"conjuntos multicamada"
EP2474496A4 (en)	2016-10-12	LIFT SYSTEM
BRPI1013015A2 (pt)	2016-03-29	"osteosíntese com nanoprata"
EP2382947A4 (en)	2012-11-28	Stent delivery system
EP2516306A4 (en)	2016-01-13	LIFT SYSTEM
EP2211083A4 (en)	2014-06-25	LIGHTING SYSTEM
BRPI1007601A2 (pt)	2016-02-16	"conjunto de luz"
EP2222278A4 (en)	2012-12-26	IMPROVED TAXAN DELIVERY SYSTEM
FR2915075B1 (fr)	2009-07-24	Article d'entretien.
EP2168898A4 (en)	2014-04-16	LIFT SYSTEM
EP2213856A4 (en)	2010-12-22	AUSPUFFROHR
EP2213220A4 (en)	2011-06-29	ENDOSCOPE SYSTEM
FR2952128B1 (fr)	2011-11-04	Dispositif d'inverseur de poussee
EP2382313A4 (en)	2013-02-20	NANOSCALE DECONTAMINATION COMPOUNDS ON ENZYME BASIS
EP2141107A4 (en)	2014-04-02	LIFT SYSTEM
BRPI0810774A2 (pt)	2015-09-15	composição de cuidado oral ou cuidado corporal.
EP2511217A4 (en)	2015-10-07	LIFT SYSTEM
FR2916954B1 (fr)	2011-11-25	Agrafe d'osteosynthese

Legal Events

Date	Code	Title	Description
2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 6A E 7A ANUIDADES.
2016-03-29	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.