BRPI0815207A2 - pirimidinas bicíclicas fundidas - Google Patents

pirimidinas bicíclicas fundidas

Info

Publication number: BRPI0815207A2
Authority: BR; Brazil
Prior art keywords: fused bicyclic; bicyclic pyrimidines; pyrimidines; fused; bicyclic
Prior art date: 2007-08-14

Application number

BRPI0815207A

Other languages

English (en)

Inventor

Zülch Armin

Zimmermann Astrid

Beneke Gerrit

Joshi Hemant

Vennemann Matthias

Hölder Swen

Beckers Thomas

Gekeler Volker

Original Assignee

Bayer Schering Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-14

Filing date

2008-08-14

Publication date

2017-03-28

2007-10-18 Priority claimed from EP07118736A external-priority patent/EP2050748A1/en

2008-08-14 Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag

2017-03-28 Publication of BRPI0815207A2 publication Critical patent/BRPI0815207A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Hematology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

BRPI0815207A 2007-08-14 2008-08-14 pirimidinas bicíclicas fundidas BRPI0815207A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IN1572MU2007		2007-08-14
EP07118736A EP2050748A1 (en)	2007-10-18	2007-10-18	Novel fused pyrimidines
PCT/EP2008/060690 WO2009021992A2 (en)	2007-08-14	2008-08-14	Fused bicyclic pyrimidines

Publications (1)

Publication Number	Publication Date
BRPI0815207A2 true BRPI0815207A2 (pt)	2017-03-28

Family

ID=40153211

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0815207A BRPI0815207A2 (pt)	2007-08-14	2008-08-14	pirimidinas bicíclicas fundidas

Country Status (37)

Country	Link
US (2)	US7776864B2 (pt)
EP (1)	EP2188291B1 (pt)
JP (1)	JP5344637B2 (pt)
KR (1)	KR20100053556A (pt)
CN (1)	CN101778851B (pt)
AR (1)	AR067945A1 (pt)
AU (1)	AU2008288392B2 (pt)
BR (1)	BRPI0815207A2 (pt)
CA (1)	CA2694058C (pt)
CL (1)	CL2008002398A1 (pt)
CO (1)	CO6260077A2 (pt)
CR (1)	CR11270A (pt)
CY (1)	CY1113486T1 (pt)
DK (1)	DK2188291T3 (pt)
DO (1)	DOP2010000058A (pt)
EA (1)	EA020996B1 (pt)
EC (1)	ECSP109964A (pt)
ES (1)	ES2396177T3 (pt)
HN (1)	HN2010000313A (pt)
HR (1)	HRP20121022T1 (pt)
IL (1)	IL203163A (pt)
MA (1)	MA31608B1 (pt)
MX (1)	MX2010001746A (pt)
MY (1)	MY169738A (pt)
NZ (1)	NZ583267A (pt)
PA (1)	PA8793201A1 (pt)
PE (1)	PE20090944A1 (pt)
PL (1)	PL2188291T3 (pt)
PT (1)	PT2188291E (pt)
RS (1)	RS52559B (pt)
SI (1)	SI2188291T1 (pt)
SV (1)	SV2010003483A (pt)
TN (1)	TN2010000070A1 (pt)
TW (1)	TWI439272B (pt)
UA (1)	UA99735C2 (pt)
UY (1)	UY31293A1 (pt)
WO (1)	WO2009021992A2 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2008050821A1 (en) *	2006-10-19	2008-05-02	Takeda Pharmaceutical Company Limited	Indole compound
CL2008002398A1 (es)	2007-08-14	2009-07-31	Bayer Ip Gmbh	Compuestos derivados de 6-(fenil piperidina) pirimidinas fusionadas con imidazol, triazol o pirozol, inhibidores de la via pi3k/akt; composicion farmaceutica; combinacion farmaceutica; y uso de los compuestos para el tratamiento de la neoplasia benigna y/o maligna y para el cancer.
MX315904B (es)	2008-05-30	2013-11-29	Amgen Inc	Inhibidores de fosfoinosituro-3 cinasa.
CN102361872B (zh) *	2009-02-13	2014-12-03	拜耳知识产权有限责任公司	作为akt抑制剂的稠合嘧啶
MA33032B1 (fr)	2009-02-13	2012-02-01	Bayer Schering Pharma Ag	Pyrimidines condensees
US8691825B2 (en)	2009-04-01	2014-04-08	Merck Sharp & Dohme Corp.	Inhibitors of AKT activity
JPWO2010125799A1 (ja)	2009-04-27	2012-10-25	塩野義製薬株式会社	Ｐｉ３ｋ阻害活性を有するウレア誘導体
CN103189379A (zh) *	2010-07-13	2013-07-03	拜耳知识产权有限责任公司	双环嘧啶
US8987273B2 (en)	2010-07-28	2015-03-24	Bayer Intellectual Property Gmbh	Substituted imidazo[1,2-B]pyridazines
WO2012136776A1 (en)	2011-04-07	2012-10-11	Bayer Intellectual Property Gmbh	Imidazopyridazines as akt kinase inhibitors
AU2014208964B2 (en)	2013-01-23	2016-09-01	Astrazeneca Ab	Chemical compounds
US20140274685A1 (en)	2013-03-15	2014-09-18	Bayer Cropscience Lp	Compositions, additives, and methods for mitigating or controlling seed dust
AU2014232160A1 (en) *	2013-03-15	2015-09-10	Bayer Cropscience Lp	Compositions, additives, and methods for mitigating or controlling seed dust
CN111212839A (zh)	2017-09-15	2020-05-29	艾杜罗生物科技公司	吡唑并嘧啶酮化合物及其用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2004502691A (ja)	2000-06-30	2004-01-29	ワイス	抗癌薬としての置換トリアゾロピリミジン
US7449488B2 (en) *	2002-06-04	2008-11-11	Schering Corporation	Pyrazolopyrimidines as protein kinase inhibitors
US7579355B2 (en)	2003-04-24	2009-08-25	Merck & Co., Inc.	Inhibitors of Akt activity
DE602005026509D1 (de)	2004-04-09	2011-04-07	Merck Sharp & Dohme	Hemmer der akt aktivität
AR050188A1 (es) *	2004-08-03	2006-10-04	Uriach Y Compania S A J	Compuestos heterociclicos condensados utiles en terapia como inhibidores de quinasas p38 y composiciones farmaceuticas que los contienen
WO2006036395A2 (en) *	2004-08-23	2006-04-06	Merck & Co., Inc.	Inhibitors of akt activity
AU2005316826A1 (en)	2004-12-15	2006-06-22	Merck Sharp & Dohme Corp.	Inhibitors of Akt activity
JP5274842B2 (ja) *	2004-12-28	2013-08-28	エグゼリクシス，インコーポレイテッド	免疫疾患、炎症疾患および増殖疾患の処置のためのセリン−スレオニンキナーゼモジュレーター（ｐ７０Ｓ６Ｋ、Ａｋｔ−１およびＡｋｔ−２）としての［１Ｈ−ピペラゾ［３，４−ｄ］ピリミジン−４−イル］−ピペラジンまたは［１Ｈ−ピペラゾ［３，４−ｄ］ピリミジン−４−イル］−ピペラジン化合物
CN101115479A (zh)	2005-02-14	2008-01-30	默克公司	Akt活性抑制剂
EP1898903B8 (en)	2005-06-10	2013-05-15	Merck Sharp & Dohme Corp.	Inhibitors of akt activity
CL2008002398A1 (es)	2007-08-14	2009-07-31	Bayer Ip Gmbh	Compuestos derivados de 6-(fenil piperidina) pirimidinas fusionadas con imidazol, triazol o pirozol, inhibidores de la via pi3k/akt; composicion farmaceutica; combinacion farmaceutica; y uso de los compuestos para el tratamiento de la neoplasia benigna y/o maligna y para el cancer.
MA33032B1 (fr) *	2009-02-13	2012-02-01	Bayer Schering Pharma Ag	Pyrimidines condensees

2008
- 2008-08-14 CL CL2008002398A patent/CL2008002398A1/es unknown
- 2008-08-14 EP EP08787224A patent/EP2188291B1/en active Active
- 2008-08-14 ES ES08787224T patent/ES2396177T3/es active Active
- 2008-08-14 RS RS20120556A patent/RS52559B/sr unknown
- 2008-08-14 WO PCT/EP2008/060690 patent/WO2009021992A2/en not_active Ceased
- 2008-08-14 MX MX2010001746A patent/MX2010001746A/es active IP Right Grant
- 2008-08-14 CN CN2008801031086A patent/CN101778851B/zh not_active Expired - Fee Related
- 2008-08-14 UY UY31293A patent/UY31293A1/es not_active Application Discontinuation
- 2008-08-14 US US12/191,703 patent/US7776864B2/en not_active Expired - Fee Related
- 2008-08-14 MY MYPI2010000150A patent/MY169738A/en unknown
- 2008-08-14 NZ NZ583267A patent/NZ583267A/en not_active IP Right Cessation
- 2008-08-14 PT PT87872248T patent/PT2188291E/pt unknown
- 2008-08-14 PE PE2008001378A patent/PE20090944A1/es not_active Application Discontinuation
- 2008-08-14 SI SI200830848T patent/SI2188291T1/sl unknown
- 2008-08-14 HR HRP20121022AT patent/HRP20121022T1/hr unknown
- 2008-08-14 UA UAA201002746A patent/UA99735C2/uk unknown
- 2008-08-14 PL PL08787224T patent/PL2188291T3/pl unknown
- 2008-08-14 JP JP2010520586A patent/JP5344637B2/ja not_active Expired - Fee Related
- 2008-08-14 AU AU2008288392A patent/AU2008288392B2/en not_active Ceased
- 2008-08-14 TW TW097131066A patent/TWI439272B/zh not_active IP Right Cessation
- 2008-08-14 CA CA2694058A patent/CA2694058C/en not_active Expired - Fee Related
- 2008-08-14 KR KR1020107003246A patent/KR20100053556A/ko not_active Abandoned
- 2008-08-14 PA PA20088793201A patent/PA8793201A1/es unknown
- 2008-08-14 DK DK08787224.8T patent/DK2188291T3/da active
- 2008-08-14 EA EA201000298A patent/EA020996B1/ru not_active IP Right Cessation
- 2008-08-14 BR BRPI0815207A patent/BRPI0815207A2/pt not_active IP Right Cessation
- 2008-08-15 AR ARP080103562A patent/AR067945A1/es unknown
2010
- 2010-01-06 IL IL203163A patent/IL203163A/en not_active IP Right Cessation
- 2010-02-12 CR CR11270A patent/CR11270A/es unknown
- 2010-02-12 MA MA32617A patent/MA31608B1/fr unknown
- 2010-02-12 CO CO10015919A patent/CO6260077A2/es active IP Right Grant
- 2010-02-12 DO DO2010000058A patent/DOP2010000058A/es unknown
- 2010-02-12 TN TNP2010000070A patent/TN2010000070A1/fr unknown
- 2010-02-12 SV SV2010003483A patent/SV2010003483A/es unknown
- 2010-02-12 EC EC2010009964A patent/ECSP109964A/es unknown
- 2010-02-12 HN HN2010000313A patent/HN2010000313A/es unknown
- 2010-03-25 US US12/731,880 patent/US8614218B2/en not_active Expired - Fee Related
2012
- 2012-12-13 CY CY20121101220T patent/CY1113486T1/el unknown

Also Published As

Publication number	Publication date
MA31608B1 (fr)	2010-08-02
HK1146273A1 (en)	2011-05-20
NZ583267A (en)	2012-03-30
CL2008002398A1 (es)	2009-07-31
JP5344637B2 (ja)	2013-11-20
US8614218B2 (en)	2013-12-24
AR067945A1 (es)	2009-10-28
ECSP109964A (es)	2010-03-31
EA201000298A1 (ru)	2010-10-29
MY169738A (en)	2019-05-14
US20090137607A1 (en)	2009-05-28
RS52559B (sr)	2013-04-30
EP2188291A2 (en)	2010-05-26
KR20100053556A (ko)	2010-05-20
JP2010535848A (ja)	2010-11-25
EA020996B1 (ru)	2015-03-31
CO6260077A2 (es)	2011-03-22
US20100184782A1 (en)	2010-07-22
CA2694058A1 (en)	2009-02-19
WO2009021992A3 (en)	2009-04-16
DOP2010000058A (es)	2010-02-28
IL203163A (en)	2015-01-29
CN101778851A (zh)	2010-07-14
HN2010000313A (es)	2013-03-18
TW200922592A (en)	2009-06-01
CA2694058C (en)	2016-06-07
CN101778851B (zh)	2013-05-08
SI2188291T1 (sl)	2013-01-31
HRP20121022T1 (hr)	2013-01-31
TN2010000070A1 (en)	2011-09-26
US7776864B2 (en)	2010-08-17
PA8793201A1 (es)	2009-04-23
PL2188291T3 (pl)	2013-06-28
ES2396177T3 (es)	2013-02-19
UA99735C2 (uk)	2012-09-25
PT2188291E (pt)	2012-12-20
WO2009021992A2 (en)	2009-02-19
AU2008288392A1 (en)	2009-02-19
MX2010001746A (es)	2010-03-10
UY31293A1 (es)	2009-03-31
CR11270A (es)	2010-05-19
PE20090944A1 (es)	2009-08-09
CY1113486T1 (el)	2016-06-22
AU2008288392B2 (en)	2013-10-24
TWI439272B (zh)	2014-06-01
DK2188291T3 (da)	2013-01-07
SV2010003483A (es)	2010-07-06
EP2188291B1 (en)	2012-09-19

Publication	Publication Date	Title
DK2188291T3 (da)	2013-01-07	Fusionerede bicykliske pyrimidiner
BRPI0815037A2 (pt)	2015-03-17	Composto bicíclico fundido
DK2154967T3 (da)	2014-04-07	Pyrimidinderivater
BRPI1009398A2 (pt)	2016-03-08	compostos de pirimidina fundida substituída
BRPI0809643A2 (pt)	2014-11-11	Derivados de heteroarila bicíclica fundida
DE112008002410A5 (de)	2010-06-10	Glasscheiben-Geländer
DE602008002748D1 (de)	2010-11-04	Linseneinführsystem
DE602008000004D1 (de)	2009-05-20	Linseneinführsystem
BRPI0907435A2 (pt)	2015-07-14	Derivados de 5-flúor pirimidina
EP2391627A4 (en)	2012-07-18	BICYCLIC PYRAZOLO HETEROCYCLES
IL213953A0 (en)	2011-08-31	Fused pyrimidines
DK2242743T3 (da)	2013-10-14	Aminopyrazolderivater
PL2135478T3 (pl)	2013-01-31	Szybka zmiana komórki obsługującej
BRPI0811115A2 (pt)	2014-12-23	Compostos de heteroarilamida pirimidona
BRPI0810926A2 (pt)	2014-11-04	Antagonista de crig
BRPI0920496A2 (pt)	2019-09-24	derivados substituídos de pirimidina etriazina
CU20090141A7 (es)	2011-04-26	Compuestos 2-amino pirimidina
BRPI0821142A2 (pt)	2015-09-15	derivados heterocíclicos bicíclicos
BRPI0811094A2 (pt)	2014-12-09	Derivados de heteroarilamida pirimidona
DK1957492T3 (da)	2011-02-28	Substituerede bicykliske pyrimidonderivater
EP2158641A4 (en)	2011-12-21	Connector
BRPI0811611A2 (pt)	2014-11-04	Compostos de triazolil aminopirimidina
ATE519980T1 (de)	2011-08-15	Verbinder
FI20070061L (fi)	2008-07-25	Sovite
ES1066007Y (es)	2008-03-01	Gafas

Legal Events

Date	Code	Title	Description
2017-04-18	B25D	Requested change of name of applicant approved	Owner name: BAYER PHARMA AKTIENGESELLSCHAFT (DE)
2017-05-02	B25A	Requested transfer of rights approved	Owner name: BAYER INTELLECTUAL PROPERTY GMBH (DE)
2018-03-06	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2018-06-12	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
2018-10-23	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2475 DE 12-06-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.