BRPI0712429A2 - Derivados de benzazepina como inibidores de re-captação de monoamina - Google Patents

Derivados de benzazepina como inibidores de re-captação de monoamina

Info

Publication number: BRPI0712429A2
Authority: BR; Brazil
Prior art keywords: retaking; monoamine; inhibitors; benzazepine derivatives; benzazepine
Prior art date: 2006-05-31

Application number

BRPI0712429-5A2A

Other languages

English (en)

Inventor

Ryan Craig Schoenfeld

Robert James Weikert

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-05-31

Filing date

2007-05-21

Publication date

2014-03-11

2007-05-21 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2014-03-11 Publication of BRPI0712429A2 publication Critical patent/BRPI0712429A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Hematology (AREA)
Psychiatry (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Child & Adolescent Psychology (AREA)
Addiction (AREA)
Hospice & Palliative Care (AREA)
Reproductive Health (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

BRPI0712429-5A2A 2006-05-31 2007-05-21 Derivados de benzazepina como inibidores de re-captação de monoamina BRPI0712429A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US80956506P	2006-05-31	2006-05-31
PCT/EP2007/054851 WO2007137953A1 (en)	2006-05-31	2007-05-21	Benzazepine derivatives as monoamine reuptake inhibitors

Publications (1)

Publication Number	Publication Date
BRPI0712429A2 true BRPI0712429A2 (pt)	2014-03-11

Family

ID=38283557

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0712429-5A2A BRPI0712429A2 (pt)	2006-05-31	2007-05-21	Derivados de benzazepina como inibidores de re-captação de monoamina

Country Status (11)

Country	Link
US (1)	US7622462B2 (pt)
EP (1)	EP2032558A1 (pt)
JP (1)	JP2009538857A (pt)
KR (1)	KR20090009275A (pt)
CN (1)	CN101437814A (pt)
AU (1)	AU2007267182A1 (pt)
BR (1)	BRPI0712429A2 (pt)
CA (1)	CA2650147A1 (pt)
IL (1)	IL195014A0 (pt)
MX (1)	MX2008014935A (pt)
WO (1)	WO2007137953A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5258561B2 (ja)	2005-07-15	2013-08-07	アルバニーモレキュラーリサーチ，インコーポレイテッド	アリール置換およびヘテロアリール置換テトラヒドロベンズアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
JP2011116663A (ja) *	2008-05-30	2011-06-16	Otsuka Pharmaceut Co Ltd	ベンゾジアゼピン化合物
KR20120093408A (ko) *	2009-12-04	2012-08-22	에프. 호프만-라 로슈 아게	모노아민 재흡수 억제제로서의 테트라히드로퀴놀린 인돌 유도체
BR112012012905A2 (pt) *	2009-12-04	2017-03-01	Hoffmann La Roche	derivados de difenil azepina como inibidores da reabsorção de monoamina
US8722662B2 (en)	2010-10-07	2014-05-13	Takeda Pharmaceutical Company Limited	Heterocyclic compounds
US9719213B2 (en) *	2014-12-05	2017-08-01	First Quality Tissue, Llc	Towel with quality wet scrubbing properties at relatively low basis weight and an apparatus and method for producing same
GB2568260A (en) *	2017-11-08	2019-05-15	Elekta ltd	Wall panel and associated apparatus
WO2024067463A1 (zh) *	2022-09-27	2024-04-04	苏州阿尔脉生物科技有限公司	苯并[7]环烯类衍生物、包含其的药物组合物及其医药用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5440033A (en) *	1993-11-09	1995-08-08	Schering Corporation	Indolyl-, pyrrolyl- and pyrazolyl substituted benzazepines
WO2001032624A1 (en) *	1999-11-03	2001-05-10	Du Pont Pharmaceuticals Company	4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
JP2005518414A (ja) *	2001-12-21	2005-06-23	スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー	ドーパミン受容体のモジュレーターとしての７−スルホニル−３−ベンゾアゼピン誘導体およびｃｎｓ障害の治療のためのその使用
US7541357B2 (en)	2004-07-15	2009-06-02	Amr Technology, Inc.	Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
JP5258561B2 (ja) *	2005-07-15	2013-08-07	アルバニーモレキュラーリサーチ，インコーポレイテッド	アリール置換およびヘテロアリール置換テトラヒドロベンズアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用

2007
- 2007-05-21 EP EP07729295A patent/EP2032558A1/en not_active Withdrawn
- 2007-05-21 KR KR1020087029233A patent/KR20090009275A/ko not_active Ceased
- 2007-05-21 CA CA002650147A patent/CA2650147A1/en not_active Abandoned
- 2007-05-21 JP JP2009512540A patent/JP2009538857A/ja active Pending
- 2007-05-21 MX MX2008014935A patent/MX2008014935A/es active IP Right Grant
- 2007-05-21 CN CNA2007800163558A patent/CN101437814A/zh active Pending
- 2007-05-21 WO PCT/EP2007/054851 patent/WO2007137953A1/en not_active Ceased
- 2007-05-21 AU AU2007267182A patent/AU2007267182A1/en not_active Abandoned
- 2007-05-21 BR BRPI0712429-5A2A patent/BRPI0712429A2/pt not_active IP Right Cessation
- 2007-05-31 US US11/809,828 patent/US7622462B2/en not_active Expired - Fee Related
2008
- 2008-10-30 IL IL195014A patent/IL195014A0/en unknown

Also Published As

Publication number	Publication date
AU2007267182A1 (en)	2007-12-06
JP2009538857A (ja)	2009-11-12
KR20090009275A (ko)	2009-01-22
EP2032558A1 (en)	2009-03-11
CA2650147A1 (en)	2007-12-06
MX2008014935A (es)	2008-12-09
US7622462B2 (en)	2009-11-24
US20070281920A1 (en)	2007-12-06
WO2007137953A1 (en)	2007-12-06
CN101437814A (zh)	2009-05-20
IL195014A0 (en)	2009-08-03

Publication	Publication Date	Title
BRPI0812825A2 (pt)	2014-12-09	Derivados ftalazinona como inibidores de parp-1
CR10831A (es)	2009-06-18	INHIBIDORES ESPIRO CETONA DE ACETIL-CoA CARBOXILASA
BRPI0813707A2 (pt)	2014-12-30	Derivados de pirimidinil-piridazinona
BRPI0820112A2 (pt)	2015-05-05	Derivados de isoxazol-piridina
BRPI0809992A2 (pt)	2014-10-14	Derivados de pirrolopirimidina
BRPI0811639A2 (pt)	2014-09-30	Cicloaquilaminas fenil substituídas como inibidores da recaptação de monoamina
BRPI0820113A2 (pt)	2015-05-05	Derivados de isoxazolo-piridazina
BRPI0906625A2 (pt)	2015-07-14	Derivados de tio-2-amino-quinolina-6-substituída úteis como inibidores da beta-secretase (bace)
PT1976828T (pt)	2017-03-10	Derivados de diamina como inibidores de leucotrieno a4 hidrolase
BRPI0812155A2 (pt)	2019-09-24	derivados de espiroindolinona
BRPI0920135A2 (pt)	2019-09-24	imidazopiridazinacarbonitrilos úteis como inibidores de quinase
BRPI0817935A2 (pt)	2015-04-07	Derivados de biarila
ATE471085T1 (de)	2010-07-15	Zigarettenersatz
BRPI0815135A2 (pt)	2015-02-03	Derivados de azepina como inibidores de gama secretase.
ATE475662T1 (de)	2010-08-15	Dihydropyrazolopyrimidinonderivate
ATE483711T1 (de)	2010-10-15	Spiroindolinonderivate
BRPI0814797A2 (pt)	2015-02-03	Inibidores dna-pk
ATE469905T1 (de)	2010-06-15	Pyridopyrimidinonderivate
ATE512135T1 (de)	2011-06-15	Spiroindolinonderivate
BRPI0915064A2 (pt)	2015-10-27	derivados de qunoxalinadiona
DK2035394T3 (da)	2009-10-05	2-pyrazincarboxamidderivater
BRPI0814236A2 (pt)	2015-01-06	Derivados de quinazolinamida
EP2072519A4 (en)	2009-10-21	DIARYLKETIMINDERIVAT
BRPI0812518A2 (pt)	2015-03-31	Derivados de indazolamida
BRPI0913832A2 (pt)	2015-10-20	derivados de pirrolopiridinilpirimidin-2-ilamina

Legal Events

Date	Code	Title	Description
2014-08-26	B08L	Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette]	Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 6A E 7A ANUIDADES.
2020-11-10	B08I	Publication cancelled [chapter 8.9 patent gazette]	Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2277 DE 26/08/2014 POR TER SIDO INDEVIDA.
2020-11-17	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 6A, 7A, 8A, 9A, 10A, 11A, 12A E 13A ANUIDADES.
2021-03-09	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.