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BRPI0415966A - combinações compreendendo antagonistas do receptor ampa para tratamento de esquizofrenia - Google Patents

combinações compreendendo antagonistas do receptor ampa para tratamento de esquizofrenia

Info

Publication number
BRPI0415966A
BRPI0415966A BRPI0415966-7A BRPI0415966A BRPI0415966A BR PI0415966 A BRPI0415966 A BR PI0415966A BR PI0415966 A BRPI0415966 A BR PI0415966A BR PI0415966 A BRPI0415966 A BR PI0415966A
Authority
BR
Brazil
Prior art keywords
combinations
treatment
schizophrenia
ampa receptor
receptor antagonists
Prior art date
Application number
BRPI0415966-7A
Other languages
English (en)
Inventor
Kurt Lingenhoehl
Ferenc Martenyi
Silvio Ofner
Mary Ann Karolchyk
Hans O Kalkman
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0415966A publication Critical patent/BRPI0415966A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"COMBINAçõES COMPREENDENDO ANTAGONISTAS DO RECEPTOR AMPA PARA TRATAMENTO DE ESQUIZOFRENIA". A presente invenção refere-se a combinações adequadas para o tratamento de distúrbios psiquiátricos/neurológicos, em particular esquizofrenia. As combinações compreendem pelo menos um antagonista do receptor AMPA e pelo menos um composto selecionado do grupo que consiste em (a) drogas antiepilépticas selecionadas de barbituratos e derivados dos mesmos, benzodiazepinas, carboxamidas, hidantoínas, succinimidas, ácido valpróico e outros derivados de ácidos graxos e outras drogas antiepilépticas, (b) antipsicóticos convencionais e (c) antipsicóticos atípicos.
BRPI0415966-7A 2003-10-28 2004-10-27 combinações compreendendo antagonistas do receptor ampa para tratamento de esquizofrenia BRPI0415966A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0325175.8A GB0325175D0 (en) 2003-10-28 2003-10-28 Organic compounds
PCT/EP2004/012150 WO2005049040A1 (en) 2003-10-28 2004-10-27 Combinations comprising ampa receptor antagonists for the treatment of schizophrenia

Publications (1)

Publication Number Publication Date
BRPI0415966A true BRPI0415966A (pt) 2007-01-23

Family

ID=29725529

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0415966-7A BRPI0415966A (pt) 2003-10-28 2004-10-27 combinações compreendendo antagonistas do receptor ampa para tratamento de esquizofrenia

Country Status (10)

Country Link
US (1) US20070082873A1 (pt)
EP (1) EP1682157A1 (pt)
JP (1) JP2007509883A (pt)
CN (1) CN1874779A (pt)
AU (1) AU2004290890B2 (pt)
BR (1) BRPI0415966A (pt)
CA (1) CA2541293A1 (pt)
GB (1) GB0325175D0 (pt)
MX (1) MXPA06004780A (pt)
WO (1) WO2005049040A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009003673A (es) * 2006-10-04 2009-04-22 Pfizer Prod Inc Derivados de piridido[4,3-d]pirimidin-4(3h)-ona como antagonistas de los receptores de calcio.
IL219628A (en) 2009-12-11 2014-09-30 Autifony Therapeutics Ltd Imidazolidinedione derivatives
KR101862375B1 (ko) 2010-12-06 2018-05-29 오티포니 세라피틱스 리미티드 Kv3 억제제로서 유용한 하이단토인 유도체
US9669030B2 (en) 2012-05-22 2017-06-06 Autifony Therapeutics Limited Hydantoin derivatives as Kv3 inhibitors
US9422252B2 (en) 2012-05-22 2016-08-23 Autifony Therapeutics Limited Triazoles as Kv3 inhibitors
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0424179A3 (en) * 1989-10-20 1991-12-27 John William Olney Use of combined excitatory amino acid and cholinergic antagonists to prevent neurological deterioration
GB9022785D0 (en) * 1990-10-19 1990-12-05 Merck Sharp & Dohme Therapeutic agents
US5891871A (en) * 1996-03-21 1999-04-06 Cocensys, Inc. Substituted 2,3-benzodiazepin-4-ones and the use thereof
ES2264171T3 (es) * 1996-10-24 2006-12-16 Novartis Ag Acidos aminoalcanofosfonicos sustituidos.
DK1026950T3 (da) * 1997-10-27 2006-06-26 Univ California Behandling af skizofreni med ampakiner og neuroleptika
US6420369B1 (en) * 1999-05-24 2002-07-16 Ortho-Mcneil Pharmaceutical, Inc. Anticonvulsant derivatives useful in treating dementia
EP1187604A4 (en) * 1999-05-28 2004-02-11 Jeffrey Berlant CONNECTIONS AND METHODS FOR TREATING POST-TRAUMATIC STRESS FAILURES
US6191117B1 (en) * 2000-07-10 2001-02-20 Walter E. Kozachuk Methods of producing weight loss and treatment of obesity
MXPA04007752A (es) * 2002-02-08 2005-06-17 Abbott Lab Terapia de combinacion para tratamiento de esquizofrenia.
TW200403066A (en) * 2002-04-30 2004-03-01 Novartis Ag New uses of substituted aminoalkanephosphonic acids
DE10332473A1 (de) * 2003-07-16 2005-02-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol für die Behandlung von Epilepsie
DE10332487A1 (de) * 2003-07-16 2005-02-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol für die Behandlung von chronisch nozizeptiven Schmerzen

Also Published As

Publication number Publication date
JP2007509883A (ja) 2007-04-19
US20070082873A1 (en) 2007-04-12
EP1682157A1 (en) 2006-07-26
AU2004290890B2 (en) 2008-10-30
MXPA06004780A (es) 2006-07-03
CA2541293A1 (en) 2005-06-02
WO2005049040A1 (en) 2005-06-02
GB0325175D0 (en) 2003-12-03
CN1874779A (zh) 2006-12-06
AU2004290890A1 (en) 2005-06-02

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.