[go: up one dir, main page]

BRPI0408407A - composto, composição farmacêutica, método de tratamento ou prevenção de dor, uso de um composto, e, processo para produzir um composto - Google Patents

composto, composição farmacêutica, método de tratamento ou prevenção de dor, uso de um composto, e, processo para produzir um composto

Info

Publication number
BRPI0408407A
BRPI0408407A BRPI0408407-1A BRPI0408407A BRPI0408407A BR PI0408407 A BRPI0408407 A BR PI0408407A BR PI0408407 A BRPI0408407 A BR PI0408407A BR PI0408407 A BRPI0408407 A BR PI0408407A
Authority
BR
Brazil
Prior art keywords
compound
pain
compounds
alone
pharmaceutically acceptable
Prior art date
Application number
BRPI0408407-1A
Other languages
English (en)
Inventor
Prasun K Chakravarty
Michael H Fisher
Brenda Palucki
Min K Park
William H Parsons
Bishan Zhou
James P Carey
Douglas E Frantz
Michael H Kress
Damian Weaver
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of BRPI0408407A publication Critical patent/BRPI0408407A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"COMPOSTO, COMPOSIçãO FARMACêUTICA, MéTODO DE TRATAMENTO OU PREVENçãO DE DOR, USO DE UM COMPOSTO, E, PROCESSO PARA PRODUZIR UM COMPOSTO". Os compostos de triazóis biaril-substituídos representados pelas Fórmulas (I), (II) ou (III), ou seus sais farmaceuticamente aceitáveis, e um processo para produzir tais compostos e seus sais. As composições farmacêuticas compreendem uma quantidade eficaz dos compostos presentes, ou sozinhos ou em combinação com um ou mais outros compostos terapeuticamente ativos, e um portador farmaceuticamente aceitável. Métodos de tratar condições associadas ou causadas pela atividade do canal de sódio, incluindo, por exemplo, a dor aguda, a dor crónica, a dor visceral, a dor inflamatória, a dor neuropática, epilepsia, a síndrome de intestino irritável, depressão, ansiedade, esclerose múltipla e distúrbio bipolar, compreendem administrar uma quantidade eficaz dos presentes compostos, ou sozinhos ou em combinação com um ou mais outros compostos terapeuticamente ativos. Um método de administrar anestesia local compreende administrar uma quantidade eficaz de um composto da presente invenção, ou sozinho ou em combinação com um ou mais outros composto terapeuticamente ativos, e um portador farmaceuticamente aceitável.
BRPI0408407-1A 2003-03-18 2004-03-12 composto, composição farmacêutica, método de tratamento ou prevenção de dor, uso de um composto, e, processo para produzir um composto BRPI0408407A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45595203P 2003-03-18 2003-03-18
PCT/US2004/007830 WO2004083190A1 (en) 2003-03-18 2004-03-12 Biaryl substituted triazoles as sodium channel blockers

Publications (1)

Publication Number Publication Date
BRPI0408407A true BRPI0408407A (pt) 2006-03-21

Family

ID=33030073

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408407-1A BRPI0408407A (pt) 2003-03-18 2004-03-12 composto, composição farmacêutica, método de tratamento ou prevenção de dor, uso de um composto, e, processo para produzir um composto

Country Status (34)

Country Link
US (2) US7326726B2 (pt)
EP (1) EP1606269B1 (pt)
JP (1) JP4482554B2 (pt)
KR (1) KR100737721B1 (pt)
CN (2) CN1788002A (pt)
AR (1) AR044503A1 (pt)
AT (1) ATE412639T1 (pt)
AU (1) AU2004221885C1 (pt)
BR (1) BRPI0408407A (pt)
CA (1) CA2519252C (pt)
CL (1) CL2004000551A1 (pt)
CY (1) CY1108720T1 (pt)
DE (1) DE602004017438D1 (pt)
DK (1) DK1606269T3 (pt)
EC (1) ECSP056018A (pt)
EG (1) EG25994A (pt)
ES (1) ES2314387T3 (pt)
HR (1) HRP20050816A2 (pt)
IS (1) IS8001A (pt)
JO (1) JO2480B1 (pt)
MA (1) MA27665A1 (pt)
MX (1) MXPA05009847A (pt)
MY (1) MY142651A (pt)
NO (1) NO20054775L (pt)
NZ (1) NZ542205A (pt)
PE (1) PE20041066A1 (pt)
PL (1) PL1606269T3 (pt)
PT (1) PT1606269E (pt)
RU (1) RU2356897C2 (pt)
SI (1) SI1606269T1 (pt)
TW (1) TWI337605B (pt)
UA (1) UA81660C2 (pt)
WO (2) WO2004083189A1 (pt)
ZA (1) ZA200506906B (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1587821T6 (da) 2002-12-19 2025-05-26 Scripps Research Inst Sammensætninger og fremgangsmåder til stabilisering af trans-thyretin og inhibering af transthyretin-fejlfoldning
MY142651A (en) * 2003-03-18 2010-12-15 Merck Sharp & Dohme Biaryl substituted triazoles as sodium channel blockers
NZ547044A (en) * 2003-11-10 2010-05-28 Merck Sharp & Dohme Substituted triazoles as sodium channel blockers
AU2005245470A1 (en) 2004-05-20 2005-12-01 Foldrx Pharmaceuticals, Inc. 2-((hetero) aryl)-benzoxazole compounds and derivatives, compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding
TW200728258A (en) 2005-10-10 2007-08-01 Glaxo Group Ltd Novel compounds
ATE472529T1 (de) 2005-10-10 2010-07-15 Glaxo Group Ltd Prolinamidderivate als natriumkanalmodulatoren
TW200730494A (en) 2005-10-10 2007-08-16 Glaxo Group Ltd Novel compounds
WO2008090114A1 (en) 2007-01-24 2008-07-31 Glaxo Group Limited Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-)
US8299107B2 (en) * 2007-02-08 2012-10-30 Synta Pharmaceuticals Corporation Triazole compounds that modulate HSP90 activity
JP4827986B2 (ja) 2007-06-08 2011-11-30 マンカインド コーポレ−ション ＩＲＥ−１αインヒビター
EA025824B1 (ru) 2009-07-27 2017-02-28 Джилид Сайэнс, Инк. Конденсированные гетероциклические соединения в качестве модуляторов ионных каналов
ES2529119T3 (es) 2010-07-02 2015-02-17 Gilead Sciences, Inc. Compuestos heterocíclicos condensados como moduladores de canales iónicos
KR20140033377A (ko) 2011-05-10 2014-03-18 길리애드 사이언시즈, 인코포레이티드 나트륨 채널 조절제로서의 융합된 헤테로시클릭 화합물
TW201837023A (zh) 2011-07-01 2018-10-16 美商基利科學股份有限公司 作為離子通道調節劑之稠合雜環化合物
NO3175985T3 (pt) 2011-07-01 2018-04-28
CN103781770B (zh) 2011-09-16 2016-04-13 辉瑞公司 转甲状腺素蛋白解离抑制剂的固体形式
WO2013131018A1 (en) * 2012-03-02 2013-09-06 Zalicus Pharmaceuticals Ltd. Biaryl inhibitors of the sodium channel
TWI568722B (zh) 2012-06-15 2017-02-01 葛蘭馬克製藥公司 作爲ｍＰＧＥＳ－１抑制劑之三唑酮化合物
JP6456909B2 (ja) 2013-03-15 2019-01-23 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ Ｌｘｒ調節因子
ES2912881T3 (es) 2014-12-23 2022-05-30 Convergence Pharmaceuticals Procedimiento para preparar derivados de alfa-carboxamida pirrolidina
JP6616244B2 (ja) * 2015-05-29 2019-12-04 北興化学工業株式会社 新規なヒドロキシフェニルボロン酸エステルとその製造方法、およびヒドロキシビフェニル化合物の製造法
US11192856B2 (en) 2017-10-05 2021-12-07 Biogen Inc. Process for preparing alpha-carboxamide pyrrolidine derivatives
KR102512548B1 (ko) 2017-12-22 2023-03-22 삼성디스플레이 주식회사 유기 전계 발광 소자 및 유기 전계 발광 소자용 함질소 화합물
WO2019171234A1 (en) * 2018-03-09 2019-09-12 Pi Industries Ltd. Heterocyclic compounds as fungicides
CN108794413A (zh) * 2018-06-25 2018-11-13 青岛科技大学 一种1,2,4-三氮唑-3-甲酰胺的合成方法
CN108863965A (zh) * 2018-06-25 2018-11-23 青岛科技大学 一锅法制备1,2,4-三氮唑-3-甲酰胺的方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US875782A (en) * 1907-04-29 1908-01-07 Walter H Cook Fast-nut.
TW226993B (pt) * 1992-05-29 1994-07-21 Kumiai Chemical Industry Co
US5455252A (en) * 1993-03-31 1995-10-03 Syntex (U.S.A.) Inc. Optionally substituted 6,8-quinolines
JP3682075B2 (ja) * 1993-04-16 2005-08-10 クミアイ化学工業株式会社 トリアゾール誘導体及び殺虫、殺ダニ剤
MY129541A (en) * 1996-06-25 2007-04-30 Novartis Ag Substituded 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators
IT1292091B1 (it) * 1997-06-05 1999-01-25 Geange Ltd Derivati eterociclici aromatici azotati,procedimento per la loro preparazione e loro impiego come antigestativi,immunosoppressori e
GB9726987D0 (en) 1997-12-22 1998-02-18 Glaxo Group Ltd Compounds
IL145508A0 (en) 1999-03-26 2002-06-30 Euro Celtique Sa Aryl substituted pyrazole, imidazole, oxazole, thiazole and pyrrole derivatives and pharmaceutical compositions containing the same
AR029489A1 (es) 2000-03-10 2003-07-02 Euro Celtique Sa Piridinas, pirimidinas, pirazinas, triazinas sustituidas por arilo, composiciones farmaceuticas y el uso de las mismas para la manufactura de un medicamento
US6962936B2 (en) * 2001-04-27 2005-11-08 Vertex Pharmaceuticals Incorporated Triazole-derived kinase inhibitors and uses thereof
US6797722B2 (en) * 2002-05-03 2004-09-28 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole for the treatment of autoimmune diseases
HRP20050001A2 (en) * 2002-07-09 2005-08-31 Bristol-Myers Squibb Company A Delaware (Usa) Corp Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method
KR100467668B1 (ko) * 2002-08-07 2005-01-24 씨제이 주식회사 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물
KR100470075B1 (ko) * 2002-11-21 2005-02-05 씨제이 주식회사 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물
JO2397B1 (en) * 2002-12-20 2007-06-17 ميرك شارب اند دوم كوربوريشن Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors
MY142651A (en) * 2003-03-18 2010-12-15 Merck Sharp & Dohme Biaryl substituted triazoles as sodium channel blockers
NZ547044A (en) * 2003-11-10 2010-05-28 Merck Sharp & Dohme Substituted triazoles as sodium channel blockers

Also Published As

Publication number Publication date
SI1606269T1 (sl) 2009-02-28
PL1606269T3 (pl) 2009-04-30
JO2480B1 (en) 2009-01-20
NO20054775D0 (no) 2005-10-17
ES2314387T3 (es) 2009-03-16
CN101289428A (zh) 2008-10-22
JP4482554B2 (ja) 2010-06-16
MY142651A (en) 2010-12-15
UA81660C2 (ru) 2008-01-25
RU2005132168A (ru) 2006-04-27
ATE412639T1 (de) 2008-11-15
ECSP056018A (es) 2006-01-27
KR20050109583A (ko) 2005-11-21
US20080171777A1 (en) 2008-07-17
EG25994A (en) 2012-11-28
NZ542205A (en) 2008-11-28
EP1606269B1 (en) 2008-10-29
MXPA05009847A (es) 2005-12-05
WO2004083189A1 (en) 2004-09-30
MA27665A1 (fr) 2005-12-01
AU2004221885C1 (en) 2010-09-23
US7326726B2 (en) 2008-02-05
KR100737721B1 (ko) 2007-07-11
JP2006520782A (ja) 2006-09-14
CA2519252A1 (en) 2004-09-30
EP1606269A1 (en) 2005-12-21
AU2004221885A1 (en) 2004-09-30
US20050119261A1 (en) 2005-06-02
DK1606269T3 (da) 2009-02-09
WO2004083190A1 (en) 2004-09-30
US7572822B2 (en) 2009-08-11
TWI337605B (en) 2011-02-21
IS8001A (is) 2005-08-29
CA2519252C (en) 2008-11-18
PE20041066A1 (es) 2005-01-22
DE602004017438D1 (de) 2008-12-11
HRP20050816A2 (hr) 2006-04-30
RU2356897C2 (ru) 2009-05-27
AU2004221885B2 (en) 2010-04-22
AR044503A1 (es) 2005-09-14
ZA200506906B (en) 2007-02-28
TW200505876A (en) 2005-02-16
CY1108720T1 (el) 2013-09-04
CN1788002A (zh) 2006-06-14
CL2004000551A1 (es) 2005-01-21
PT1606269E (pt) 2008-12-16
NO20054775L (no) 2005-12-16

Similar Documents

Publication Publication Date Title
BRPI0408407A (pt) composto, composição farmacêutica, método de tratamento ou prevenção de dor, uso de um composto, e, processo para produzir um composto
US8889736B2 (en) Formulations for the treatment of pain
NZ504986A (en) Erythromycin and azalide derivatives and pharmaceutical compositions thereof, useful as antibacterial agents and antoprotozoa agents
BR0313352A (pt) Composto, composições farmacêuticas, método para a produção de um composto, método para o tratamento, prevenção ou a melhora de um distúrbio e método para o tratamento de um mamìfero
EP1091745A4 (en) TREATMENT OF HYPERPROLIFERATIVE DISEASES
BRPI0415167A (pt) composto de amina como ligandos de canal de ìon e usos dos mesmos
BR0111126A (pt) Derivados de aminoácidos cìclicos úteis como agentes farmacêuticos
BRPI9810519A (pt) derivados de 4''-substituído-9-desoxo-9a-aza-9a-homoeritromicina a e composição farmacêutica compreendendo os mesmos.
DE60316779D1 (de) Thiadiazolylpiperazinderivate geeignet für die behandlung bzw. prävention von schmerzen
BR9904150A (pt) Composições de proteìnas estabilizadas
BRPI0415179A (pt) derivados de amida como ligandos de canal de ìon e composições farmacêuticas e métodos de empregar as mesmas
AP2001002142A0 (en) 13-membered azalides and their use as antibiotic agents.
BR0207978A (pt) N-but-3enil norbuprenorfina e métodos de uso
IS8438A (is) Setin tríasól sem natríum gangahemla
BR9812148A (pt) Derivados de eritromicina 6,9-ligados em ponte
BR9813317A (pt) Composto, composição farmacêutica para tratar infecções bacterianas, e, processos para tratar infecções bacterianas, e para preparar um composto
BR9812577A (pt) Composto, processo para preparar o mesmo, composição farmacêutica, e, processo para tratar infecções bacterianas
BRPI0409151A (pt) uso de derivados de 10-hidróxi-10,11-diidrocarbamazepina para o tratamento de transtornos afetivos
BRPI0407529A (pt) uso de r-10-hidróxi-10,11-dihidro-carbamazepina em dor neuropática
BR9809489A (pt) Composto, processo para preparar o mesmo, e, composição farmacêutica e processo para tratar infecções bacterianas.
TW200503673A (en) Methods for the treatment of pain and traumatic injury using benzamides and compositions containing the same

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25D Requested change of name of applicant approved

Owner name: MERCK SHARP AND DOHME CORP. (US)

Free format text: NOME ALTERADO DE: MERCK AND CO., INC.

B25A Requested transfer of rights approved

Owner name: SCHERING CORPORATION, (US)

B25D Requested change of name of applicant approved

Owner name: MERCK SHARP AND DOHME CORP. (US)

B25G Requested change of headquarter approved

Owner name: MERCK SHARP AND DOHME CORP. (US)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2368 DE 24-05-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.