[go: up one dir, main page]

BR9911549A - Processo de produção de fitase em levedura - Google Patents

Processo de produção de fitase em levedura

Info

Publication number
BR9911549A
BR9911549A BR9911549-2A BR9911549A BR9911549A BR 9911549 A BR9911549 A BR 9911549A BR 9911549 A BR9911549 A BR 9911549A BR 9911549 A BR9911549 A BR 9911549A
Authority
BR
Brazil
Prior art keywords
production process
yeast
phytase
phytase production
yeast phytase
Prior art date
Application number
BR9911549-2A
Other languages
English (en)
Other versions
BRPI9911549B1 (pt
Inventor
Xingen Lei
Original Assignee
Cornell Res Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22302276&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9911549(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cornell Res Foundation Inc filed Critical Cornell Res Foundation Inc
Publication of BR9911549A publication Critical patent/BR9911549A/pt
Publication of BRPI9911549B1 publication Critical patent/BRPI9911549B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Devices For Dispensing Beverages (AREA)

Abstract

"PROCESSO DE PRODUçãO DE FITAS EM LEVEDURA". A presente invenção refere-se a um processo para produzir um polipeptídeo ou proteína heteróloga apresentando atividade de fitase em um sistema de levedura. A invenção também proporciona proteínas com atividade de fitase que apresentam maior termoestabilidade. As cepas de levedura que produzem uma fitase heteróloga e os vetores utilizados para produzir a fitase também são proporcionados.
BRPI9911549A 1998-06-25 1999-06-23 processo de produção de fitase appa de escherichia coli em levedura, proteína ou polipeptídeo, vetor de expressão, e, levedura BRPI9911549B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/104,769 US6451572B1 (en) 1998-06-25 1998-06-25 Overexpression of phytase genes in yeast systems
PCT/US1999/014106 WO1999067398A2 (en) 1998-06-25 1999-06-23 Overexpression of phytase genes in yeast systems

Publications (2)

Publication Number Publication Date
BR9911549A true BR9911549A (pt) 2001-03-20
BRPI9911549B1 BRPI9911549B1 (pt) 2016-08-30

Family

ID=22302276

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9911549A BRPI9911549B1 (pt) 1998-06-25 1999-06-23 processo de produção de fitase appa de escherichia coli em levedura, proteína ou polipeptídeo, vetor de expressão, e, levedura

Country Status (18)

Country Link
US (6) US6451572B1 (pt)
EP (3) EP1090129B2 (pt)
JP (2) JP2002518052A (pt)
KR (1) KR100870886B1 (pt)
CN (1) CN100365126C (pt)
AT (1) ATE317904T1 (pt)
AU (1) AU772071B2 (pt)
BR (1) BRPI9911549B1 (pt)
CA (1) CA2332180C (pt)
CZ (1) CZ301680B6 (pt)
DE (1) DE69929886C5 (pt)
DK (2) DK1090129T4 (pt)
ES (2) ES2560661T3 (pt)
HU (1) HUP0102800A2 (pt)
MX (1) MX258391B (pt)
PL (1) PL345408A1 (pt)
PT (1) PT1688500E (pt)
WO (1) WO1999067398A2 (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6720014B1 (en) * 1997-08-13 2004-04-13 Diversa Corporation Phytase-containing foodstuffs and methods of making and using them
US6451572B1 (en) 1998-06-25 2002-09-17 Cornell Research Foundation, Inc. Overexpression of phytase genes in yeast systems
US6841370B1 (en) 1999-11-18 2005-01-11 Cornell Research Foundation, Inc. Site-directed mutagenesis of Escherichia coli phytase
KR100375673B1 (ko) * 2000-01-29 2003-03-15 대한민국 피타제 생산 효모 균주를 함유하는 사료용 조성물
US6737262B1 (en) * 2000-07-11 2004-05-18 Robert I. Bolla Animal feed containing polypeptides
JP3813055B2 (ja) * 2000-07-26 2006-08-23 ソレイ リミテッド ライアビリティ カンパニー 高純度植物タンパク材料の製造方法
AU2002255851B2 (en) * 2001-03-23 2008-03-06 Advanced Bionutrition Microbial feeds for aquaculture and agriculture
EP1450627B1 (en) 2001-10-31 2012-09-05 Phytex, Llc Use of phytase containing animal food
TWI262083B (en) * 2001-12-28 2006-09-21 Syngenta Participations Ag Microbially-expressed thermotolerant phytase for animal feed
TW200305430A (en) * 2001-12-28 2003-11-01 Syngenta Participations Ag Thermotolerant phytase for animal feed
SE0200911D0 (sv) * 2002-03-22 2002-03-22 Chalmers Technology Licensing Phytase active yeast
CN100398645C (zh) * 2002-08-16 2008-07-02 广东肇庆星湖生物科技股份有限公司 用化学合成和分子进化获得酵母表达高比活植酸酶基因
CN100354421C (zh) * 2002-08-16 2007-12-12 广东肇庆星湖生物科技股份有限公司 在甲醇酵母中高表达的耐高温植酸酶基因
EP1604008B1 (en) * 2002-09-13 2010-12-22 Cornell Research Foundation, Inc. Using mutations to improve aspergillus phytases
AU2003291063A1 (en) * 2002-11-19 2004-06-15 Board Of Trustees Operating Michigan State University Antioxidant and antimicrobial agents and methods of use thereof
US20070184521A1 (en) * 2003-07-03 2007-08-09 Alissa Jourdan Novel phytase and gene
US7276362B2 (en) 2004-01-30 2007-10-02 Roche Diagnostics Operations, Inc. Recombinant histidine-tagged inosine monophosphate dehydrogenase polypeptides
US20070224126A1 (en) * 2004-06-01 2007-09-27 Therese Dufresne Index and Method of use of Adapted Food Compositions for Dysphagic Persons
WO2006012739A1 (en) * 2004-08-02 2006-02-09 UNIVERSITé LAVAL Nutritional ingredient containing bioavailable mineral nutrients
KR100754242B1 (ko) 2005-08-29 2007-09-03 (주)진바이오텍 효모 유래 프로모터를 이용한 대장균 유래 파이타제의제조방법
US7919297B2 (en) 2006-02-21 2011-04-05 Cornell Research Foundation, Inc. Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase
US8540984B2 (en) * 2006-08-03 2013-09-24 Cornell Research Foundation, Inc. Phytases with improved thermal stability
US8192734B2 (en) 2007-07-09 2012-06-05 Cornell University Compositions and methods for bone strengthening
EP2258854A1 (en) * 2009-05-20 2010-12-08 FH Campus Wien Eukaryotic host cell comprising an expression enhancer
RU2409670C1 (ru) * 2009-07-10 2011-01-20 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП ГосНИИгенетика) Рекомбинантная плазмида для экспрессии в дрожжах pichia pastoris гена фитазы (варианты), штамм дрожжей pichia pastoris - продуцент фитазы (варианты)
EP2743347A2 (en) 2011-08-08 2014-06-18 Fertinagro Nutrientes, S.L. Novel phytase, method for obtaining same and use thereof
WO2014138679A1 (en) 2013-03-08 2014-09-12 Biogrammatics, Inc. Yeast promoters for protein expression
EP2964765B1 (en) 2013-03-08 2019-05-08 Keck Graduate Institute of Applied Life Sciences Yeast promoters from pichia pastoris
WO2019023034A2 (en) * 2017-07-27 2019-01-31 Locus Agriculture Ip Company, Llc EFFICIENT PRODUCTION OF PICHIA YEASTS AND USE THEREOF TO IMPROVE PLANT AND ANIMAL HEALTH
EP3453719A1 (en) 2017-09-07 2019-03-13 Huvepharma Eood New thermostable phytases with high catalytic efficacy
CN109601822B (zh) * 2019-01-22 2022-11-08 北京三强核力辐射工程技术有限公司 一种生物碱协同辐照降解动物源性食品中抗生素的方法
CN110029120B (zh) * 2019-03-19 2022-03-01 青岛蔚蓝生物集团有限公司 一种植酸酶高产菌株及其应用
CN112680464B (zh) * 2020-12-10 2022-04-26 南京农业大学 一种单甲基砷和三价锑氧化酶基因arsV及其编码的蛋白和应用

Family Cites Families (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA940070A (en) 1968-12-23 1974-01-15 Jim S. Berry Stabilized aqueous enzyme composition
US3860484A (en) 1972-09-28 1975-01-14 Xerox Corp Enzyme stabilization
DE2426988C2 (de) 1974-06-04 1985-02-14 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Trägerbindung biologisch aktiver Proteine
US3966971A (en) 1975-01-02 1976-06-29 Grain Processing Corporation Separation of protein from vegetable sources
DE2931999A1 (de) 1979-08-03 1981-02-26 Schering Ag Herstellung und anwendung von neukombinierten plasmiden mit genen fuer alkalische phosphatasen
DE3126759A1 (de) 1981-07-07 1983-01-27 Boehringer Mannheim Gmbh, 6800 Mannheim Loesliche leber-uricase, verfahren zu ihrer herstellung und verwendung
JPS5931799A (ja) 1982-08-16 1984-02-20 Science & Tech Agency Ｂ型肝炎ウイルス遺伝子を組込んだ組換えプラスミド
US4470968A (en) 1983-01-13 1984-09-11 Miles Laboratories, Inc. Pasteurized therapeutically active blood coagulation factor concentrates
SE450325B (sv) 1983-02-23 1987-06-22 Tricum Ab Kostfiberprodukt baserad pa skaldelar fran froet hos ceralier
AR245671A1 (es) 1984-08-15 1994-02-28 American Safety Closure Perfeccionamientos en tapones de material plastico a prueba de manipulaciones indebidas.
SE465951B (sv) 1984-10-23 1991-11-25 Perstorp Ab Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav
DE3515586A1 (de) 1985-04-30 1986-11-06 Boehringer Mannheim Gmbh, 6800 Mannheim Stabilisiertes sarcosinoxidase-praeparat
US5024941A (en) * 1985-12-18 1991-06-18 Biotechnica International, Inc. Expression and secretion vector for yeast containing a glucoamylase signal sequence
JPH0655146B2 (ja) 1985-12-27 1994-07-27 財団法人化学及血清療法研究所 シヤトルベクタ−
US5780292A (en) 1987-04-29 1998-07-14 Alko Group Ltd. Production of phytate degrading enzymes in trichoderma
NL8702735A (nl) 1987-11-17 1989-06-16 Dorr Oliver Inc Werkwijze voor het weken van granen met een nieuw enzympreparaat.
JPH04501662A (ja) 1988-09-26 1992-03-26 ザ・サルク・インスティチュート・バイオテクノロジー／インダストリアル・アソシエイツ・インコーポレーテッド 混合給送組換え酵母発酵
GB8826429D0 (en) 1988-11-11 1988-12-14 Univ Leeds Ind Service Ltd Enzyme stabilisation systems
US5316770A (en) 1989-02-16 1994-05-31 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
US5366736A (en) 1989-02-16 1994-11-22 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
UA27702C2 (uk) 1989-09-27 2000-10-16 Гіст-Брокейдс Н.В. Фрагмент геномної днк, що кодує фітазу aspergillus niger,фрагмент кднк, що кодує фітазу aspergillus niger, рекомбінантна плазмідна днк для експресії фітази в aspergillus (варіанти), штам aspergillus-продуцент фітази aspergillus (варіанти), спосіб одержання фітази, рекомбінанта фітаза aspergillus niger
CZ289014B6 (cs) 1989-09-27 2001-10-17 Dsm N. V. Vyčiątěná a izolovaná sekvence DNA kódující fungální fytázu, konstrukt pro expresi, vektory a transformované hostitelské buňky a způsob produkce fytázy
US5593963A (en) 1990-09-21 1997-01-14 Mogen International Expression of phytase in plants
PT97110B (pt) 1990-03-23 1998-11-30 Gist Brocades Nv Processo para catalisar reaccoes acelaraveis por enzimas, mediante adicao ao meio reaccional de sementes de plantas transgenicas e para obtencao das referidas sementes
KR100225087B1 (ko) 1990-03-23 1999-10-15 한스 발터라벤 피타아제의 식물내 발현
GB9006642D0 (en) 1990-03-24 1990-05-23 Gibson Timothy D Enzyme stabilisation
DE4011084A1 (de) 1990-04-05 1991-10-10 Boehringer Mannheim Gmbh Saccharid-modifizierte, wasserloesliche proteine
US5200399A (en) 1990-09-14 1993-04-06 Boyce Thompson Institute For Plant Research, Inc. Method of protecting biological materials from destructive reactions in the dry state
EP0513332A4 (en) 1990-11-14 1993-03-17 Cargill, Incorporated Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
US5268273A (en) 1990-12-14 1993-12-07 Phillips Petroleum Company Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same
DE4119281A1 (de) 1991-06-12 1992-12-17 Basf Ag Verfahren zur herstellung von enzymzubereitungen
WO1993014645A1 (en) 1992-01-24 1993-08-05 Gist-Brocades N.V Method for the preparation of feed pellets
FI943707A0 (fi) 1992-02-13 1994-08-10 Gist Brocades Nv Stabiloidut vesipitoiset nestemäiset fytaasivalmisteet
US5216770A (en) * 1992-03-11 1993-06-08 Holt William J Support device
WO1994003072A1 (en) 1992-07-31 1994-02-17 Panlabs Incorporated Recombinant cells, dna constructs, vectors and methods for expressing phytate degrading enzymes in desired ratios
DK0619369T3 (da) 1993-04-05 2003-10-06 Aveve Nv Phytathydrolyse og enzymsammensætning til hydrolyse af phytat
JP2696057B2 (ja) 1993-05-11 1998-01-14 ニチモウ株式会社 穀類を原料とした生成物の製造方法
DK82893D0 (da) 1993-07-08 1993-07-08 Novo Nordisk As Peptid
FR2715802B1 (fr) 1994-02-04 1996-03-15 Rhone Poulenc Nutrition Animal Utilisation d'enzymes dans l'alimentation des animaux pour réduire les rejets azotés.
US5955448A (en) 1994-08-19 1999-09-21 Quadrant Holdings Cambridge Limited Method for stabilization of biological substances during drying and subsequent storage and compositions thereof
DE69524951T3 (de) 1994-04-22 2009-07-09 Novozymes A/S Verfahren zum verbessern der löslichkeit von pflanzlichen proteinen
US6291221B1 (en) 1994-04-25 2001-09-18 Roche Vitamins Inc. Heat tolerant phytases
EP0684313B1 (en) 1994-04-25 2006-07-05 DSM IP Assets B.V. Polypeptides with phytase activity
US5830732A (en) 1994-07-05 1998-11-03 Mitsui Toatsu Chemicals, Inc. Phytase
GB9416841D0 (en) 1994-08-19 1994-10-12 Finnfeeds Int Ltd An enzyme feed additive and animal feed including it
FR2729971B1 (fr) 1995-01-31 1997-06-06 Roquette Freres Composition nutritive resultant de la trempe du mais et son procede d'obtention
US5935624A (en) 1995-02-06 1999-08-10 Wisconsin Alumni Research Foundation Low phosphorus animal feed containing 1α-hydroxylated vitamin D compounds and method of preparing
US5556771A (en) 1995-02-10 1996-09-17 Gen-Probe Incorporated Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification
SK40697A3 (en) 1995-07-28 1997-10-08 Gist Brocades Bv Salt-stabilized enzyme preparations
AU7489896A (en) 1995-11-02 1997-05-22 Novo Nordisk A/S Feed enzyme preparations
DK172530B1 (da) 1995-11-10 1998-11-23 Leo Pharm Prod Ltd Tilsætningsprodukt til drikkevand og foder til dyr samt fremgangsmåde for tilsætning
US5830696A (en) 1996-12-05 1998-11-03 Diversa Corporation Directed evolution of thermophilic enzymes
AU2077197A (en) 1996-03-18 1997-10-10 Novo Nordisk Biotech, Inc. Polypeptides having phytase activity and nucleic acids encoding same
WO1997038096A1 (en) 1996-04-05 1997-10-16 Kyowa Hakko Kogyo Co., Ltd. Novel phytase and gene encoding said phytase
EP0902623A1 (en) 1996-04-23 1999-03-24 Novo Nordisk A/S Animal feed additives
US5900525A (en) 1996-04-26 1999-05-04 Wisconsin Alumni Research Foundation Animal feed compositions containing phytase derived from transgenic alfalfa and methods of use thereof
EP1015826A2 (en) 1996-05-29 2000-07-05 Universal Preservation Technologies, Inc. Long-term shelf preservation by vitrification
US5985605A (en) 1996-06-14 1999-11-16 Her Majesty The Queen In Right Of Canada, As Represented By The Dept. Of Agriculture & Agri-Food Canada DNA sequences encoding phytases of ruminal microorganisms
US6323316B1 (en) 1996-06-18 2001-11-27 The United States Of America As Represented By The Secretary Of The Department Of And Human Services Fibroblast growth factor receptor activating gene 1 and related compositions and methods
FR2751333B1 (fr) 1996-07-18 1998-09-25 Roquette Freres Composition nutritive amelioree resultant de la trempe du mais et son procede d'obtention
FR2751987B1 (fr) 1996-08-01 1998-12-31 Biocem Phytases de plantes et applications biotechnologiques
GB2316082A (en) 1996-08-13 1998-02-18 Finnfeeds Int Ltd Phytase
SE507355C2 (sv) 1996-09-18 1998-05-18 Semper Ab Förfarande för reducering av halten fytat i korn av spannmål
EA003632B1 (ru) 1996-09-25 2003-08-28 Киова Хакко Когио Ко., Лтд. Фитазы из микроорганизма monascus anka, способ их получения и корм для животных, содержащий указанные фитазы
GB2319030A (en) 1996-11-05 1998-05-13 Finnfeeds Int Ltd Phytase extracted from soybean
US6039942A (en) 1996-12-20 2000-03-21 Novo Nordick A/S Phytase polypeptides
AU5477898A (en) 1997-01-09 1998-08-03 Novo Nordisk A/S Phytase combinations
KR100222638B1 (ko) 1997-01-20 1999-10-01 배희동 종자를 이용한 효소산물 및 사료원료의 생산
CA2231948C (en) 1997-03-25 2010-05-18 F. Hoffmann-La Roche Ag Modified phytases
KR100206453B1 (ko) 1997-03-27 1999-07-01 박원훈 신규한플라즈미드를이용하여형질전환시킨균주 이.채씨오엘아이.피와이로부터생산된피타제
CN1151256C (zh) 1997-05-28 2004-05-26 基本应用私人有限公司 工业用酶的增强
EP1457560A1 (en) 1997-06-04 2004-09-15 Basf Aktiengesellschaft High-activity phytase compositions
NZ330940A (en) 1997-07-24 2000-02-28 F Production of consensus phytases from fungal origin using computer programmes
US6183740B1 (en) 1997-08-13 2001-02-06 Diversa Corporation Recombinant bacterial phytases and uses thereof
US6720014B1 (en) 1997-08-13 2004-04-13 Diversa Corporation Phytase-containing foodstuffs and methods of making and using them
US7432097B2 (en) 1997-08-13 2008-10-07 Verenium Corporation Phytases, nucleic acids encoding them and methods of making and using them
US5876997A (en) 1997-08-13 1999-03-02 Diversa Corporation Phytase
US6855365B2 (en) 1997-08-13 2005-02-15 Diversa Corporation Recombinant bacterial phytases and uses thereof
US7078035B2 (en) 1997-08-13 2006-07-18 Diversa Corporation Phytases, nucleic acids encoding them and methods for making and using them
US6022555A (en) 1997-09-05 2000-02-08 Wisconsin Alumni Research Foundation Animal feed containing carboxylic acids
DK0911416T3 (da) 1997-10-01 2006-08-14 Dsm Ip Assets Bv Fremgangsmåde til fremstilling af protein
DE19743683A1 (de) 1997-10-02 1999-04-08 Basf Ag Verfahren zur Änderung der Substratspezifität von Enzymen
US20010018197A1 (en) 1997-12-23 2001-08-30 Protein Technologies International, Inc. Method for producing ultrapure vegetable protein materials
ATE235836T1 (de) 1997-12-23 2003-04-15 Cargill Bv Proteine enthaltendes futtermittel und verfahren zur herstellung
CN1192103C (zh) 1998-01-27 2005-03-09 三井化学株式会社 生产植酸酶的方法
US6514495B1 (en) 1998-03-23 2003-02-04 Novozymes A/S Phytase varinats
DE69940306D1 (de) 1998-03-23 2009-03-05 Novozymes As Varianten der phytase
CA2323581A1 (en) 1998-04-01 1999-10-07 Dsm N.V. Application of phytase in feed having low content of phytate
US6451572B1 (en) 1998-06-25 2002-09-17 Cornell Research Foundation, Inc. Overexpression of phytase genes in yeast systems
GB2340727B (en) 1998-08-19 2002-05-22 Univ Saskatchewan Process for converting phytate into inorganic phosphate
US6284502B1 (en) 1998-08-21 2001-09-04 University Of Saskatchewan Process for converting phytate into inorganic phosphate
EP1117771B1 (en) 1998-10-02 2003-04-23 Novozymes A/S Solid phytase compositions
WO2000041509A2 (en) 1999-01-14 2000-07-20 Novozymes Biotech, Inc. Polypeptides having acid phosphatase activity and nucleic acids encoding same
EP1151088B1 (en) 1999-01-22 2006-08-30 Novozymes A/S Improved phytases
US6720174B1 (en) 1999-01-28 2004-04-13 Novozymes A/S Phytases
BR0004713A (pt) 1999-02-10 2000-12-19 Dsm Nv Granulados contendo enzimas de alimentação
EP1165806B1 (en) 1999-03-31 2005-08-03 Cornell Research Foundation, Inc. Phosphatases with improved phytase activity
CN1258333C (zh) 1999-05-31 2006-06-07 雀巢制品公司 低植酸含量的谷物产品
CA2382084C (en) 1999-08-13 2013-03-05 The Victoria University Of Manchester Phytase enzymes, nucleic acids encoding phytase enzymes and vectors and host cells incorporating same
EP1092764B1 (en) 1999-10-11 2010-01-06 DSM IP Assets B.V. Continuous fermentation
US6509432B2 (en) * 1999-10-25 2003-01-21 Kansai Paint Co., Ltd. Ordinary temperature curable coating composition
US6841370B1 (en) 1999-11-18 2005-01-11 Cornell Research Foundation, Inc. Site-directed mutagenesis of Escherichia coli phytase
JP2003531574A (ja) 1999-11-18 2003-10-28 コーネル リサーチ ファウンデーション、インコーポレイティッド 大腸菌フィターゼの部位特異的変異誘発
FR2804691B1 (fr) 2000-02-04 2003-11-07 Roquette Freres Composition azotee resultant de l'hydrolyse du gluten de mais et son procede de fabrication
DE60133802T2 (de) 2000-02-08 2009-06-25 Dsm Ip Assets B.V. Verwendung von säurestabilen proteasen in tierfutter
CA2411230A1 (en) 2000-05-25 2001-11-29 Diversa Corporation Dietary aids and methods of use thereof
AU2002230953A1 (en) 2000-12-12 2002-06-24 Diversa Corporation Recombinant phytases and uses thereof
EP1450627B1 (en) 2001-10-31 2012-09-05 Phytex, Llc Use of phytase containing animal food
TWI262083B (en) 2001-12-28 2006-09-21 Syngenta Participations Ag Microbially-expressed thermotolerant phytase for animal feed
JP3970811B2 (ja) 2002-09-09 2007-09-05 独立行政法人科学技術振興機構 リンカー化合物及びリガンド、並びにそれらの製造方法
EP1604008B1 (en) 2002-09-13 2010-12-22 Cornell Research Foundation, Inc. Using mutations to improve aspergillus phytases
US7658922B2 (en) 2005-06-24 2010-02-09 Ab Enzymes Gmbh Monoclonal antibodies, hybridoma cell lines, methods and kits for detecting phytase
US7919297B2 (en) 2006-02-21 2011-04-05 Cornell Research Foundation, Inc. Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase
WO2007112739A1 (en) 2006-04-04 2007-10-11 Novozymes A/S Phytase variants
US8540984B2 (en) 2006-08-03 2013-09-24 Cornell Research Foundation, Inc. Phytases with improved thermal stability
US8192734B2 (en) 2007-07-09 2012-06-05 Cornell University Compositions and methods for bone strengthening
US20090074994A1 (en) * 2007-09-14 2009-03-19 Mclean Linda L Kit for Decorating A Car
GB0922467D0 (en) 2009-04-24 2010-02-03 Danisco Feed supplement
US8334124B1 (en) 2009-09-23 2012-12-18 The United States Of America As Represented By The Secretary Of Agriculture Modified Aspergillus niger phytase

Also Published As

Publication number Publication date
DK1090129T4 (da) 2013-06-03
DK1688500T3 (en) 2016-03-14
ES2560661T3 (es) 2016-02-22
US20060153902A1 (en) 2006-07-13
ES2255281T5 (es) 2013-06-04
US7026150B2 (en) 2006-04-11
DE69929886D1 (de) 2006-04-20
PT1688500E (pt) 2016-02-15
US7829318B2 (en) 2010-11-09
DE69929886C5 (de) 2021-07-15
CZ20004805A3 (cs) 2002-04-17
MXPA00012794A (es) 2001-05-01
US8455232B2 (en) 2013-06-04
AU772071B2 (en) 2004-04-08
US20130244303A1 (en) 2013-09-19
KR100870886B1 (ko) 2008-11-28
AU5083799A (en) 2000-01-10
CN100365126C (zh) 2008-01-30
EP3020815A1 (en) 2016-05-18
US20020192791A1 (en) 2002-12-19
WO1999067398A9 (en) 2000-06-02
EP1688500A2 (en) 2006-08-09
CA2332180A1 (en) 1999-12-29
US7312063B2 (en) 2007-12-25
JP2010046085A (ja) 2010-03-04
US8993300B2 (en) 2015-03-31
US20020102692A1 (en) 2002-08-01
CZ301680B6 (cs) 2010-05-26
MX258391B (es) 2008-07-02
PL345408A1 (en) 2001-12-17
EP1090129B1 (en) 2006-02-15
EP1090129B2 (en) 2013-05-01
DE69929886T3 (de) 2013-11-14
CA2332180C (en) 2014-08-19
EP1090129A2 (en) 2001-04-11
ES2255281T3 (es) 2006-06-16
US6451572B1 (en) 2002-09-17
EP1688500B1 (en) 2015-12-30
HUP0102800A2 (hu) 2001-12-28
EP1688500A3 (en) 2008-11-05
WO1999067398A2 (en) 1999-12-29
ATE317904T1 (de) 2006-03-15
US20110053246A1 (en) 2011-03-03
BRPI9911549B1 (pt) 2016-08-30
WO1999067398A3 (en) 2000-04-20
DE69929886T2 (de) 2006-08-24
CN1313898A (zh) 2001-09-19
KR20010043988A (ko) 2001-05-25
US20080227150A1 (en) 2008-09-18
DK1090129T3 (da) 2006-06-06
JP2002518052A (ja) 2002-06-25

Similar Documents

Publication Publication Date Title
BR9911549A (pt) Processo de produção de fitase em levedura
DE69435049D1 (de) Chimäre proteine zur vermeidung der komplementaktivierung
DE69333766D1 (de) Herstellung von phytat-degradierenden enzymen in trichoderma
BR9609791A (pt) Processo para estabilizar proteínas em um meio ácido com um pectina de elevado teor em éster
DE60033138D1 (de) Polypeptide mit galaktoseoxidaseaktivität und dafür kodierende nukleisäuren
BR0015114A (pt) Sequências de ácido nucléico e de aminoácido, construção de ácido nucleico, vetor, microorganismo, l-pantolactona hidrolase, e, processo para preparar d-pantolactona
BR8301918A (pt) Proteina,sequencia de dna,veiculo de expressao replicavel,microorganismo ou cultura celular,plasmideo,composicao,cultura de celulas,utilizacao de tal proteina,processo de expressao,processo para producao de um veiculo de expressao e processo para preparacao de uma proteina uroquinase
DE69521752D1 (de) Verfahren für die Herstellung von Proteinen
ATE323770T1 (de) Polypeptide mit lysophospholipaseaktivität und nukleinesäuren die sie kodieren
PT1204738E (pt) Processo para a diminuicao da formacao de espuma durante a cultura de um microrganismo
ES2191011T3 (es) Acido nucleico, vector de expresion y composiciones para la identificacion y sintesis de sialiltransferasas recombinantes.
ATE212059T1 (de) Methoden zur identifizierung heterofunktionaler fusionsproteine
DE69837475D1 (de) Polypeptide mit aminopeptidaseaktivität und dafür kodierende nukleinsäuren
ATE281528T1 (de) Rekombinante ribonuklease proteine
GB9801408D0 (en) Frozen food product
PT635025E (pt) Processo para preparar proteinas modificadas
AUPM772494A0 (en) Improvements in production of proteins in host cells
FI945877A0 (fi) Menetelmä proteiini C:n tuottamiseksi
KR890008166A (ko) 융합 단백질의 선택적 분해 방법
ATE346941T1 (de) Protein-disulfidisomerase-gen eines methylotrophen hefestammes
WO1995021916A3 (en) Pp32: a newly identified cd45-associated protein
ATE282701T1 (de) Rekombinante dnase b aus streptococcus pyogenes
EP0326799A3 (de) Verfahren zur enzymatischen Peptidsynthese
YU47990A (sh) Sekvenca cdna za ovčji preprokimozin

Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10O(IX), 11, 13 E 25 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 30/08/2016, OBSERVADAS AS CONDICOES LEGAIS.