BR9907025B1 - Polissacarídeos sintéticos e uso dos mesmos - Google Patents

Polissacarídeos sintéticos e uso dos mesmos

Info

Publication number: BR9907025B1
Authority: BR; Brazil
Prior art keywords: synthetic polysaccharides; polysaccharides; synthetic; treatment; pathologies associated
Prior art date: 1998-01-19

Application number

BRPI9907025-1B1A

Other languages

English (en)

Other versions

BRPI9907025B8 (pt

BR9907025A (pt

Inventor

Johannes Basten

Cornelia Dreef-Tromp

Pierre-Alexandre Driguez

Philippe Duchaussoy

Jean-Marc Herbert

Maurice Petitou

Boeckel Constant Van

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-19

Filing date

1999-01-13

Publication date

2013-12-10

1999-01-13 Application filed filed Critical

2000-10-17 Publication of BR9907025A publication Critical patent/BR9907025A/pt

2013-12-10 Publication of BR9907025B1 publication Critical patent/BR9907025B1/pt

2016-09-13 Publication of BRPI9907025B8 publication Critical patent/BRPI9907025B8/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Materials Engineering (AREA)
Hematology (AREA)
Polymers & Plastics (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Medicinal Preparation (AREA)

BRPI9907025A 1998-01-19 1999-01-13 polissacarídeos sintéticos e uso dos mesmos BRPI9907025B8 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9800515A FR2773804B1 (fr)	1998-01-19	1998-01-19	Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant
PCT/FR1999/000044 WO1999036443A1 (fr)	1998-01-19	1999-01-13	Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant

Publications (3)

Publication Number	Publication Date
BR9907025A BR9907025A (pt)	2000-10-17
BR9907025B1 true BR9907025B1 (pt)	2013-12-10
BRPI9907025B8 BRPI9907025B8 (pt)	2016-09-13

Family

ID=9521914

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI9907025A BRPI9907025B8 (pt)	1998-01-19	1999-01-13	polissacarídeos sintéticos e uso dos mesmos

Country Status (40)

Country	Link
US (1)	US6528497B1 (pt)
EP (1)	EP1049721B1 (pt)
JP (1)	JP4402835B2 (pt)
KR (1)	KR100513196B1 (pt)
CN (1)	CN1165550C (pt)
AR (1)	AR013019A1 (pt)
AT (1)	ATE209219T1 (pt)
AU (1)	AU741748B2 (pt)
BR (1)	BRPI9907025B8 (pt)
CA (1)	CA2317465C (pt)
CO (1)	CO4970795A1 (pt)
CZ (1)	CZ297815B6 (pt)
DE (1)	DE69900718T2 (pt)
DK (1)	DK1049721T3 (pt)
DZ (1)	DZ2709A1 (pt)
EE (1)	EE04157B1 (pt)
EG (1)	EG23982A (pt)
ES (1)	ES2168000T3 (pt)
FR (1)	FR2773804B1 (pt)
GT (1)	GT199900003A (pt)
HR (1)	HRP20000480B1 (pt)
HU (1)	HU228333B1 (pt)
IL (1)	IL137241A0 (pt)
MA (1)	MA26597A1 (pt)
MY (1)	MY119090A (pt)
NO (1)	NO329903B1 (pt)
NZ (1)	NZ505492A (pt)
PE (1)	PE20000269A1 (pt)
PL (1)	PL202802B1 (pt)
PT (1)	PT1049721E (pt)
RU (1)	RU2211224C2 (pt)
SA (1)	SA99191113B1 (pt)
SI (1)	SI1049721T1 (pt)
SK (1)	SK283411B6 (pt)
TR (1)	TR200002078T2 (pt)
TW (1)	TW548279B (pt)
UA (1)	UA60352C2 (pt)
UY (1)	UY25356A1 (pt)
WO (1)	WO1999036443A1 (pt)
ZA (1)	ZA99355B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2814463B1 (fr) *	2000-09-22	2002-11-15	Sanofi Synthelabo	Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
FR2874924B1 (fr) *	2004-09-09	2006-12-01	Sanofi Aventis Sa	Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) *	2004-12-23	2013-08-01	Merck Sharp & Dohme	包含生物素殘基之抗血栓雙重抑制劑
GB0507577D0 (en)	2005-04-14	2005-05-18	Novartis Ag	Organic compounds
IL188647A0 (en) *	2008-01-08	2008-11-03	Orina Gribova	Adaptable structured drug and supplements administration system (for oral and/or transdermal applications)
US8791064B2 (en) *	2008-04-24	2014-07-29	Technion Research And Development Foundation Ltd.	Beta-lactoglobulin-polysaccharide nanoparticles for hydrophobic bioactive compounds
JP2011522805A (ja)	2008-05-30	2011-08-04	モメンタファーマシューティカルズインコーポレイテッド	糖構造ならびにそのような構造を作製および使用する方法
FR2935386B1 (fr) *	2008-08-26	2010-09-10	Sanofi Aventis	Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine
WO2010117803A2 (en) *	2009-03-30	2010-10-14	University Of Georgia Research Foundation, Inc.	Heparan sulfate synthesis
WO2011004376A1 (en)	2009-07-09	2011-01-13	Oshadi Drug Administration Ltd.	Matrix carrier compositions, methods and uses
CN104245718B (zh) *	2009-07-31	2016-11-09	可靠生物医药公司	制备磺达肝素钠的方法及其合成中使用的中间体
FR2949114B1 (fr)	2009-08-14	2011-08-26	Sanofi Aventis	OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949115B1 (fr)	2009-08-14	2012-11-02	Sanofi Aventis	OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
US8420790B2 (en)	2009-10-30	2013-04-16	Reliable Biopharmaceutical Corporation	Efficient and scalable process for the manufacture of Fondaparinux sodium
EP2614089A1 (fr)	2010-09-10	2013-07-17	Sanofi-Aventis	Polysaccharides biotinyles a activite antithrombotique et presentant une stabilite metabolique amelioree
US9005664B2 (en)	2010-10-17	2015-04-14	Technion Research And Development Foundation Ltd.	Denatured lactoglobulin and polyphenol coassemblies
FR2970969B1 (fr)	2011-01-27	2013-10-18	Sanofi Aventis	Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2704226B1 (fr) *	1993-04-22	1995-07-21	Sanofi Elf	3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
NZ260933A (en) *	1993-07-16	1996-07-26	Hercules Inc	Cation-complexed polysaccharides; use in foods and pharmaceuticals
FR2749849B1 (fr) *	1996-06-14	1998-09-04	Sanofi Sa	Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2751334B1 (fr) *	1996-07-19	1998-10-16	Sanofi Sa	Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
CZ427499A3 (cs) *	1998-05-29	2000-05-17	The Procter & Gamble Company	Jemné topické antimikrobiální přípravky

1998
- 1998-01-19 FR FR9800515A patent/FR2773804B1/fr not_active Expired - Lifetime
1999
- 1999-01-13 WO PCT/FR1999/000044 patent/WO1999036443A1/fr not_active Ceased
- 1999-01-13 DK DK99900524T patent/DK1049721T3/da active
- 1999-01-13 IL IL13724199A patent/IL137241A0/xx not_active IP Right Cessation
- 1999-01-13 AU AU19745/99A patent/AU741748B2/en not_active Ceased
- 1999-01-13 JP JP2000540158A patent/JP4402835B2/ja not_active Expired - Fee Related
- 1999-01-13 UA UA2000074011A patent/UA60352C2/uk unknown
- 1999-01-13 CZ CZ20002635A patent/CZ297815B6/cs not_active IP Right Cessation
- 1999-01-13 AT AT99900524T patent/ATE209219T1/de active
- 1999-01-13 BR BRPI9907025A patent/BRPI9907025B8/pt not_active IP Right Cessation
- 1999-01-13 KR KR10-2000-7007824A patent/KR100513196B1/ko not_active Expired - Fee Related
- 1999-01-13 US US09/600,506 patent/US6528497B1/en not_active Expired - Lifetime
- 1999-01-13 SI SI9930025T patent/SI1049721T1/xx unknown
- 1999-01-13 RU RU2000119753/04A patent/RU2211224C2/ru not_active IP Right Cessation
- 1999-01-13 TR TR2000/02078T patent/TR200002078T2/xx unknown
- 1999-01-13 DE DE69900718T patent/DE69900718T2/de not_active Expired - Lifetime
- 1999-01-13 PT PT99900524T patent/PT1049721E/pt unknown
- 1999-01-13 CA CA002317465A patent/CA2317465C/en not_active Expired - Fee Related
- 1999-01-13 HR HR970630A patent/HRP20000480B1/xx not_active IP Right Cessation
- 1999-01-13 NZ NZ505492A patent/NZ505492A/en not_active IP Right Cessation
- 1999-01-13 CN CNB998022438A patent/CN1165550C/zh not_active Expired - Fee Related
- 1999-01-13 HU HU0102009A patent/HU228333B1/hu not_active IP Right Cessation
- 1999-01-13 EP EP99900524A patent/EP1049721B1/fr not_active Expired - Lifetime
- 1999-01-13 EE EEP200000429A patent/EE04157B1/xx unknown
- 1999-01-13 ES ES99900524T patent/ES2168000T3/es not_active Expired - Lifetime
- 1999-01-13 SK SK1078-2000A patent/SK283411B6/sk not_active IP Right Cessation
- 1999-01-13 PL PL341875A patent/PL202802B1/pl unknown
- 1999-01-14 GT GT199900003A patent/GT199900003A/es unknown
- 1999-01-15 MA MA25431A patent/MA26597A1/fr unknown
- 1999-01-16 DZ DZ990010A patent/DZ2709A1/xx active
- 1999-01-16 EG EG5499A patent/EG23982A/xx active
- 1999-01-18 TW TW088100716A patent/TW548279B/zh not_active IP Right Cessation
- 1999-01-18 AR ARP990100172A patent/AR013019A1/es active IP Right Grant
- 1999-01-18 MY MYPI99000203A patent/MY119090A/en unknown
- 1999-01-18 UY UY25356A patent/UY25356A1/es not_active Application Discontinuation
- 1999-01-19 CO CO99002526A patent/CO4970795A1/es unknown
- 1999-01-19 ZA ZA9900355A patent/ZA99355B/xx unknown
- 1999-01-19 PE PE1999000044A patent/PE20000269A1/es not_active Application Discontinuation
- 1999-02-27 SA SA99191113A patent/SA99191113B1/ar unknown
2000
- 2000-07-17 NO NO20003662A patent/NO329903B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
FR2773804B1 (fr)	2000-02-18
DZ2709A1 (fr)	2003-09-01
PE20000269A1 (es)	2000-06-15
GT199900003A (es)	2000-07-07
JP4402835B2 (ja)	2010-01-20
SI1049721T1 (en)	2002-06-30
EP1049721B1 (fr)	2001-11-21
HRP20000480A2 (en)	2000-12-31
PT1049721E (pt)	2002-05-31
PL341875A1 (en)	2001-05-07
PL202802B1 (pl)	2009-07-31
US6528497B1 (en)	2003-03-04
AR013019A1 (es)	2000-11-22
WO1999036443A1 (fr)	1999-07-22
DK1049721T3 (da)	2002-04-02
MA26597A1 (fr)	2004-12-20
HK1030002A1 (en)	2001-04-20
EE04157B1 (et)	2003-10-15
KR100513196B1 (ko)	2005-09-07
CN1288470A (zh)	2001-03-21
SA99191113B1 (ar)	2006-10-11
ATE209219T1 (de)	2001-12-15
JP2002509164A (ja)	2002-03-26
UY25356A1 (es)	2000-10-31
CN1165550C (zh)	2004-09-08
HU228333B1 (en)	2013-03-28
TW548279B (en)	2003-08-21
EE200000429A (et)	2001-12-17
CA2317465A1 (en)	1999-07-22
HRP20000480B1 (en)	2002-04-30
AU1974599A (en)	1999-08-02
EE200000429A1 (et)	2003-06-16
HUP0102009A1 (hu)	2001-11-28
AU741748B2 (en)	2001-12-06
TR200002078T2 (tr)	2000-11-21
UA60352C2 (uk)	2003-10-15
CA2317465C (en)	2008-05-20
SK283411B6 (sk)	2003-07-01
NZ505492A (en)	2001-12-21
EG23982A (en)	2008-02-27
FR2773804A1 (fr)	1999-07-23
DE69900718T2 (de)	2002-08-22
NO20003662L (no)	2000-09-14
ES2168000T3 (es)	2002-05-16
IL137241A0 (en)	2001-07-24
ZA99355B (en)	2000-10-11
SK10782000A3 (sk)	2001-02-12
BRPI9907025B8 (pt)	2016-09-13
NO329903B1 (no)	2011-01-24
CZ297815B6 (cs)	2007-04-04
CZ20002635A3 (cs)	2000-12-13
EP1049721A1 (fr)	2000-11-08
NO20003662D0 (no)	2000-07-17
HUP0102009A3 (en)	2003-07-28
KR20010034189A (ko)	2001-04-25
MY119090A (en)	2005-03-31
BR9907025A (pt)	2000-10-17
RU2211224C2 (ru)	2003-08-27
CO4970795A1 (es)	2000-11-07
DE69900718D1 (de)	2002-02-21

Publication	Publication Date	Title
BR9907025B1 (pt)	2013-12-10	Polissacarídeos sintéticos e uso dos mesmos
MA24139A1 (fr)	1997-12-31	Alkylsulfates .
UY34152A (es)	2013-02-28	?oxazolidinonas substituidas y su uso?.
DE69713474D1 (de)	2002-07-25	Wegwerfhöschen
ES2187079T3 (es)	2003-05-16	Nuevos conjugados colorante-polisacarido y su uso como agente de diagnostico.
DE59007513D1 (de)	1994-11-24	Anordnung zur Gewebestimulation.
ID28238A (id)	2001-05-10	Peranti pemroses benang dan penggunaannya
DE59008148D1 (de)	1995-02-09	Anordnung zur Gewebestimulation.
EP0910380A4 (en)	2000-09-27	SUBSTITUTED BENZYLIDE INDENYL FORMAMID, ACETAMIDE AND PROPIONAMIDE
EA199800666A1 (ru)	1999-02-25	Применение lhrh-аналога или комбинации lhrh-аналогов и антиэстрогена с селективным по отношению к тканям эстрогенным действием для лечения гинекологических нарушений
TR199500758A2 (tr)	1996-06-21	Lökotriarilmetanlarin hidrokarbonlarin isaretlenmesinde kullanilmasi.
DE69025517D1 (de)	1996-04-04	Nichtgewobenes gewebe, dessen herstellung und vorrichtung dazu
ITMI912509A1 (it)	1993-03-20	Uso della nimesulide nel trattamento della cataratta
PT922703E (pt)	2003-04-30	Benzocicloalcenos substituidos e sua utilizacao como substancias com efeito analgesico
FI900862A0 (fi)	1990-02-21	Hoegeffektiva polarisatorer.
ID16394A (id)	1997-09-25	Popok sekali pakai dari jenis celana
ATE425758T1 (de)	2009-04-15	Modifizierte polysaccharide mit veranderter biologischer erkennung
ES2165020T3 (es)	2002-03-01	Monohidrato de famciclovir.
FR2715945B1 (fr)	1996-08-23	Tissu.
ES2113765T3 (es)	1998-05-01	Dimaleato de n,n-dietil-8,8-dipropil-2-azaespiro(4.5)decano-2-propanamina.
FI98821B (fi)	1997-05-15	Sähköä johtava elastomeerikoostumus, sen valmistus ja käyttö
ES1020518Y (es)	1993-02-16	Avisador de uso domestico para personas con deficiencias auditivas.
TR200103662T2 (tr)	2002-05-21	Yeni kalpainler ve bunların kullanılması
ES2141923T3 (es)	2000-04-01	Uso hipocolesterolemico, antiaterosclerotico e hipotrigliceridemico de derivados aminoacetilmercapto.
RU97111990A (ru)	1999-06-10	Обезболивающее и противозудное средство

Legal Events

Date	Code	Title	Description
2006-04-25	B25A	Requested transfer of rights approved	Owner name: SANOFI-SYNTHELABO (FR) Free format text: TRANSFERIDO DE: AKZO NOBEL N.V.
2006-05-09	B25D	Requested change of name of applicant approved	Owner name: SANOFI-AVENTIS (FR) Free format text: ALTERADO DE: SANOFI-SYNTHELABO
2008-09-16	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2009-04-28	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: INDEFERIMENTO DO PRESENTE PEDIDO DE PATENTE DE INVENCAO UMA VEZ O MESMO APRESENTA REIVINDICACOES QUE NAO CUMPREM O REQUISITO DE ATIVIDADE INVENTIVA ( ARTIGOS 8O E ARTIGO 13 DA LEI 9.279/96 ), APRESENTA REIVINDICACOES QUE NAO DEFINEM, DE UM MODO CLARO E PRECISO, A MATERIA OBJETO DE PROTECAO ( ARTIGO 25 DA LEI 9.279/96 ) E O RELATORIO DESCRITIVO NAO DESCREVE, CLARA E SUFICIENTEMENTE O OBJETO, DE MODO A POSSIBILIATR A SUA REPRODUCAO POR UM TECNICO NO ASSUNTO ( ARTIGO 24 DA LEI 9.279/96)
2009-12-15	B12B	Appeal against refusal [chapter 12.2 patent gazette]
2012-02-22	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
2013-12-10	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 10/12/2013, OBSERVADAS AS CONDICOES LEGAIS.
2016-09-13	B16C	Correction of notification of the grant [chapter 16.3 patent gazette]	Free format text: REFERENTE AO DESPACHO 16.1 PUBLICADO NA RPI 2240 DE 10.12.2013, QUANTO AO NOME DO INVENTOR
2018-03-27	B15K	Others concerning applications: alteration of classification	Ipc: C08B 37/00 (2006.01)
2018-11-13	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE A 20A ANUIDADE.
2019-03-06	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)	Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2497 DE 13-11-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.