BR9811657A - Clonagem usando-se núcleos doadores oriundos de células diferenciadas não-carentes de soro - Google Patents

Clonagem usando-se núcleos doadores oriundos de células diferenciadas não-carentes de soro

Info

Publication number: BR9811657A
Authority: BR; Brazil
Prior art keywords: cells; differentiated; serum; production; cloning
Prior art date: 1997-07-03

Application number

BR9811657-6A

Other languages

English (en)

Portuguese (pt)

Inventor

Steven L Stice

Jose Cibelli

James M Robl

Paul Golueke

F Abel Ponce De Leon

D Joseph Jerry

Original Assignee

Univ Massachusetts Public Inst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-03

Filing date

1998-06-24

Publication date

2000-09-05

1998-06-24 Application filed by Univ Massachusetts Public Inst filed Critical Univ Massachusetts Public Inst

2000-09-05 Publication of BR9811657A publication Critical patent/BR9811657A/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- C12N15/877—Techniques for producing new mammalian cloned embryos
- C12N15/8771—Bovine embryos
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2517/00—Cells related to new breeds of animals
- C12N2517/02—Cells from transgenic animals
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2517/00—Cells related to new breeds of animals
- C12N2517/04—Cells produced using nuclear transfer

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Neurology (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Developmental Biology & Embryology (AREA)
General Engineering & Computer Science (AREA)
Psychology (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Toxicology (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Pathology (AREA)
Gastroenterology & Hepatology (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Molecular Biology (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Hospice & Palliative Care (AREA)

BR9811657-6A 1997-07-03 1998-06-24 Clonagem usando-se núcleos doadores oriundos de células diferenciadas não-carentes de soro BR9811657A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US88828397A	1997-07-03	1997-07-03
PCT/US1998/012800 WO1999001163A1 (fr)	1997-07-03	1998-06-24	Clonage a l'aide de noyaux donneurs a partir de cellules differentiees ne presentant pas de carence serique

Publications (1)

Publication Number	Publication Date
BR9811657A true BR9811657A (pt)	2000-09-05

Family

ID=25392916

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9811657-6A BR9811657A (pt)	1997-07-03	1998-06-24	Clonagem usando-se núcleos doadores oriundos de células diferenciadas não-carentes de soro

Country Status (9)

Country	Link
EP (1)	EP1017422A4 (fr)
JP (1)	JP2001509361A (fr)
CN (2)	CN101003800A (fr)
AU (1)	AU8154398A (fr)
BR (1)	BR9811657A (fr)
CA (1)	CA2294916A1 (fr)
IL (1)	IL133786A0 (fr)
NZ (1)	NZ502129A (fr)
WO (1)	WO1999001163A1 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6235969B1 (en) *	1997-01-10	2001-05-22	University Of Massachusetts	Cloning pigs using donor nuclei from non-quiescent differentiated cells
ATE278775T1 (de) *	1998-01-16	2004-10-15	Agrobiogen Gmbh	Effizienter kerntransfer mit fetalen fibroblasten
US6331659B1 (en)	1998-01-21	2001-12-18	University Of Hawaii	Cumulus cells as nuclear donors
JP2002511234A (ja) *	1998-03-16	2002-04-16	リレグピーティーワイリミテッド	ブタの核移植
AUPP294898A0 (en) *	1998-04-15	1998-05-07	Monash University	Method of nuclear transfer
US6781030B1 (en)	1998-11-02	2004-08-24	Trustee Of Tufts College, Ballou Hall	Methods for cloning mammals using telophase oocytes
EP1375654A3 (fr) *	1998-11-02	2008-01-16	GTC Biotherapeutics, Inc.	Mammifères trangéniques et clonés
EP1818397A1 (fr) *	1998-11-02	2007-08-15	Trustees Of Tufts College	Procéde pour le clonage des animaux
WO2000025578A2 (fr) *	1999-04-26	2000-05-11	Trustees Of Tufts College	Procedes de clonage des animaux
JP2002537785A (ja)	1999-03-04	2002-11-12	ピーピーエルセラピューティクス（スコットランド）リミテッド	体細胞の遺伝的改変とそれらの使用
EP1109890A4 (fr) *	1999-06-30	2004-12-29	Hwang Woo Suk	Procede d'obtention d'embryons humains clones au moyen de techniques de transplantation inter-especes de noyaux
EP1117763A4 (fr) *	1999-06-30	2004-12-01	Hwang Woo Suk	Procede de production de tigres clones utilisant une technique de transplantation de noyau inter-especes
RU2205536C2 (ru) *	1999-06-30	2003-06-10	Воо-Сук ХВАНГ	Способ получения клонированной коровы
CA2388497A1 (fr) *	1999-10-15	2001-04-26	Advanced Cell Technology, Inc.	Methode de production de progeniteurs differencies par culture de cellules de la morula ou de la masse cellulaire interne
DE10084883D2 (de) *	2000-06-08	2004-04-29	Trostner Jens	Verfahren zur genetischen Rekonstruktion von menschlichen Organen
NZ524523A (en)	2000-08-03	2006-02-24	Therapeutic Human Polyclonals	Production of humanized antibodies in transgenic animals
FR2814642B1 (fr)	2000-10-03	2005-07-01	Ass Pour Le Dev De La Rech En	Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee
NZ526243A (en) *	2000-11-30	2006-02-24	Stemron Inc	Isolated homozygous stem cells, differentiated cells derived therefrom, and materials and methods for making and using same
MXPA03005624A (es) *	2000-12-22	2004-12-03	Vaurox Llc	Metodos para clonar mamiferos usando cromatina reprogramada del donador o celulas donadoras.
ATE466089T1 (de)	2000-12-22	2010-05-15	Agronomique Inst Nat Rech	Positionsunabhängige und gewebespezifische expression eines transgens in der milch eines transgen-tieres
JP4381139B2 (ja)	2001-08-13	2009-12-09	エンブレクス，インコーポレイテッド	鳥類の卵の処理方法
US20030204860A1 (en) *	2002-04-01	2003-10-30	David Melican	Method for selecting cell lines to be used for nuclear transfer in mammalian species
US7612250B2 (en)	2002-07-29	2009-11-03	Trustees Of Tufts College	Nuclear transfer embryo formation method
RU2308281C1 (ru) *	2006-04-05	2007-10-20	ГУ Научно-исследовательский институт фармакологии Томского научного центра Сибирского отделения Российской академии медицинских наук (ГУ НИИ фармакологии ТНЦ СО РАМН)	Способ клонирования in vitro регионарных стволовых клеток поджелудочной железы
JP5087625B2 (ja)	2006-09-01	2012-12-05	セラピューティック・ヒューマン・ポリクローナルズ・インコーポレーテッド	非ヒトトランスジェニック動物におけるヒトまたはヒト化免疫グロブリンの発現強化
EP2267153A1 (fr)	2009-05-26	2010-12-29	Université Claude Bernard Lyon 1	Identification de la mutation du gène unc5c du récepteur de la nétrine-1 dans des cancers solides
US10865383B2 (en)	2011-07-12	2020-12-15	Lineage Cell Therapeutics, Inc.	Methods and formulations for orthopedic cell therapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1149898A2 (fr) *	1993-12-23	2001-10-31	Infigen, Inc.	Cellules d'ongules, souches d'embryons utilisees comme donneuses de noyaux et procedes de transfert de noyaux pour la production d'animaux chimeriques et transgeniques
GB9517780D0 (en) *	1995-08-31	1995-11-01	Roslin Inst Edinburgh	Biological manipulation
GB9517779D0 (en)	1995-08-31	1995-11-01	Roslin Inst Edinburgh	Biological manipulation
US5945577A (en)	1997-01-10	1999-08-31	University Of Massachusetts As Represented By Its Amherst Campus	Cloning using donor nuclei from proliferating somatic cells
ATE278775T1 (de) *	1998-01-16	2004-10-15	Agrobiogen Gmbh	Effizienter kerntransfer mit fetalen fibroblasten

1998
- 1998-06-24 NZ NZ502129A patent/NZ502129A/en unknown
- 1998-06-24 CN CNA2007100081920A patent/CN101003800A/zh active Pending
- 1998-06-24 AU AU81543/98A patent/AU8154398A/en not_active Abandoned
- 1998-06-24 CN CN98807691A patent/CN1265599A/zh active Pending
- 1998-06-24 WO PCT/US1998/012800 patent/WO1999001163A1/fr not_active Ceased
- 1998-06-24 EP EP19980931400 patent/EP1017422A4/fr not_active Withdrawn
- 1998-06-24 JP JP2000500926A patent/JP2001509361A/ja active Pending
- 1998-06-24 BR BR9811657-6A patent/BR9811657A/pt not_active Application Discontinuation
- 1998-06-24 CA CA002294916A patent/CA2294916A1/fr not_active Abandoned
- 1998-06-24 IL IL13378698A patent/IL133786A0/xx unknown

Also Published As

Publication number	Publication date
JP2001509361A (ja)	2001-07-24
CN101003800A (zh)	2007-07-25
AU8154398A (en)	1999-01-25
CN1265599A (zh)	2000-09-06
EP1017422A1 (fr)	2000-07-12
CA2294916A1 (fr)	1999-01-14
EP1017422A4 (fr)	2002-10-29
IL133786A0 (en)	2001-04-30
NZ502129A (en)	2005-02-25
WO1999001163A1 (fr)	1999-01-14

Publication	Publication Date	Title
BR9811657A (pt)	2000-09-05	Clonagem usando-se núcleos doadores oriundos de células diferenciadas não-carentes de soro
BR9811659A (pt)	2000-09-05	Clonagem de porcos usando-se núcleos doadores de células diferenciadas
BR9806872A (pt)	2000-04-18	Transferência nuclear com células diferenciadas doadoras fetais e adultas
Kaneda et al.	2010	Genetic evidence for Dnmt3a‐dependent imprinting during oocyte growth obtained by conditional knockout with Zp3‐Cre and complete exclusion of Dnmt3b by chimera formation
ATE318307T1 (de)	2006-03-15	Kultur einer zelllinieaus der inneren zellmasse von huftierembryonen.
DK1044262T3 (da)	2009-02-02	Könsspecifik inseminering af pattedyr med et lavt antal sædceller
BR9913643A (pt)	2001-09-25	Transgênese de mamìferos através de injeção intracitoplásmica de espermatozóides
Han et al.	2018	Overexpression of Tet3 in donor cells enhances goat somatic cell nuclear transfer efficiency
IL146296A0 (en)	2002-07-25	Cell reprogramming
BR0013959A (pt)	2002-05-21	Clonagem de porcos usando células ou núcleos doadores a partir de células diferenciadas e produção de porcino pluripotente
Arat et al.	2011	Using cell banks as a tool in conservation programmes of native domestic breeds: the production of the first cloned Anatolian Grey cattle
BR9913644A (pt)	2001-11-20	Método de realização de transgênese
EP1375654A3 (fr)	2008-01-16	Mammifères trangéniques et clonés
Honda	2018	Applying iPSCs for preserving endangered species and elucidating the evolution of mammalian sex determination
WO2001060152A3 (fr)	2002-04-18	Mammifere knockout transgenique non humain a gene ucp2 desactive
BR0010588A (pt)	2003-07-22	Oócitos enucleados de telofase para transferência nuclear
Shimozawa et al.	2002	Direct production of gene-targeted mice from ES cells by nuclear transfer and gene transmission to their progeny
NO20021538D0 (no)	2002-03-27	Fremgangsmåter for fremstilling av klonede og transgene pattedyr
EP1405068A4 (fr)	2007-09-26	Procedes destines au clonage de mammiferes au moyen de facteurs de remodelage
WO2003005810A3 (fr)	2003-08-14	Mammiferes non humains clones a partir de cellules donneuses a inhibition de contact
DE69940057D1 (de)	2009-01-22	Quelle für zellkerne zum kern-transfer
Gao et al.	0	VISIBLE BLUE LIGHT INDUCES MITOCHONDRIAL DYSFUNCTION IN TROUT EMBRYOS DURING EARLY DEVELOPMENT
Sansinena et al.	2007	52 Initiation of pregnancies in south african riverine rabbit (bunolagus monticulares) by interspecies nuclear transfer using adipose-derived somatic cells
Cocquet et al.	2009	The Multicopy Gene Sly Represses the Sex Chromosomes in the Male Mouse
CA2431859A1 (fr)	2000-05-11	Mammiferes transgeniques et clones

Legal Events

Date	Code	Title	Description
2008-04-15	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2008-10-14	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2009-05-19	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. PORTANTO, INDEFIRO O PRESENTE PEDIDO DE PATENTE COMO INVENCAO - DE ACORDO COM O ART. 8O DA LPI.
2009-10-06	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.