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BR9808825A - Monooxigenases do citocromo p450 - Google Patents

Monooxigenases do citocromo p450

Info

Publication number
BR9808825A
BR9808825A BR9808825-4A BR9808825A BR9808825A BR 9808825 A BR9808825 A BR 9808825A BR 9808825 A BR9808825 A BR 9808825A BR 9808825 A BR9808825 A BR 9808825A
Authority
BR
Brazil
Prior art keywords
monooxygenases
cytochrome
nitriles
dna molecules
conversion
Prior art date
Application number
BR9808825-4A
Other languages
English (en)
Inventor
Barbara Ann Halkier
Soren Bak
Racel Alice Kahn
Birger Lindberg Moller
Original Assignee
Novartis Ag
Royal Veterinary & Agricultural Univ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Royal Veterinary & Agricultural Univ filed Critical Novartis Ag
Priority claimed from PCT/EP1998/001253 external-priority patent/WO1998040470A2/en
Publication of BR9808825A publication Critical patent/BR9808825A/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8285—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for nematode resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Pest Control & Pesticides (AREA)
  • Nutrition Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

Patente de Invenção: <B>"MONOOXIGENASES DO CITOCROMO P450"<D>. Monooxigenases dependentes do citocromo P450~ II~ e moléculas de DNA que codificam essas monooxigenases são proporcionadas, monooxigenases estas que são capazes de catalisar a conversão biossintética de aldoximas em nitrilas e a conversão das nitrilas nas cianidrinas correspondentes, que são os precursores de glicosídeos cianogênicos. Além disso, a invenção proporciona métodos para obtenção de moléculas de DNA de acordo com a invenção e métodos para obtenção de plantas transgênicas resistentes a insetos, acarídeos ou nematóides, ou plantas com valor nutritivo aperfeiçoado.
BR9808825-4A 1997-03-07 1998-03-05 Monooxigenases do citocromo p450 BR9808825A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97810132 1997-03-07
EP97810954 1997-12-08
PCT/EP1998/001253 WO1998040470A2 (en) 1997-03-07 1998-03-05 Cytochrome p450 monooxygenases

Publications (1)

Publication Number Publication Date
BR9808825A true BR9808825A (pt) 2000-07-04

Family

ID=56289831

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9808825-4A BR9808825A (pt) 1997-03-07 1998-03-05 Monooxigenases do citocromo p450

Country Status (7)

Country Link
US (1) US6300544B1 (pt)
EP (1) EP0970191A2 (pt)
JP (1) JP2001514515A (pt)
KR (1) KR100583538B1 (pt)
BR (1) BR9808825A (pt)
CA (1) CA2282809A1 (pt)
PL (1) PL335643A1 (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7009088B1 (en) * 2000-12-18 2006-03-07 The Arizona Board Of Regents On Behalf Of The University Of Arizona Methods of modulating auxin production in plants
WO2003052050A2 (en) * 2001-08-03 2003-06-26 Diversa Corporation P450 enzymes, nucleic acids encoding them and methods of making and using them
KR100454237B1 (ko) * 2002-04-22 2004-10-26 한국과학기술원 알데히드옥심으로부터 니트릴의 제조방법
US20030228579A1 (en) * 2002-06-05 2003-12-11 Uri Alon Ordering genes by analysis of expression kinetics
US20070130640A1 (en) * 2005-12-06 2007-06-07 The Arizona Board Of Regents On Behalf Of The University Of Arizona A Arizona Corporation, Methods of modulating auxin production in plants
KR100834378B1 (ko) * 2007-01-19 2008-06-02 명지대학교 산학협력단 식물의 정단 우성을 강화시키는 시토크롬 ｐ４５０ 유전자
KR100834380B1 (ko) * 2007-01-19 2008-06-02 명지대학교 산학협력단 식물의 수분 스트레스 저항성을 증가시키는 시토크롬ｐ４５０ 유전자
CL2008001592A1 (es) * 2007-05-30 2009-03-06 Syngenta Participations Ag Celula vegetal que comprende una construccion de acido nucleico que contine una secuencia nucleotidica que codifica un citocromo p450, y metodo para conferir resistencia a un herbicida en la planta basado en la transformacion de la construccion descrita anteriormente.
US9347046B2 (en) 2009-01-22 2016-05-24 Syngenta Participations Ag Hydroxyphenylpyruvate dioxygenase polypeptides and methods of use
EP2573183B1 (en) 2009-01-22 2017-01-04 Syngenta Participations AG Mutant hydroxyphenylpyruvate dioxgenase polypeptids and methods of use
TWI667347B (zh) 2010-12-15 2019-08-01 瑞士商先正達合夥公司 大豆品種ｓｙｈｔ０ｈ２及偵測其之組合物及方法
UY35702A (es) 2013-08-12 2015-02-27 Basf Se Hidroxifenilpiruvato dioxigenasas resistentes a herbicidas
US11248234B2 (en) 2015-02-11 2022-02-15 Basf Se Herbicide-resistant hydroxyphenylpyruvate dioxygenases
US20190062777A1 (en) 2015-06-17 2019-02-28 BASF Agro B.V. Plants having increased tolerance to herbicides
BR112018072473A2 (pt) 2016-05-20 2019-02-19 Basf Agro Bv molécula de ácido nucleico, cassete de expressão, célula vegetal, planta, semente, métodos para expressar um ácido nucleico, produzir uma planta, controlar vegetação e cultivar a planta, combinação útil para o controle, processo para preparar uma combinação e uso de uma combinação
US11149030B2 (en) 2016-07-27 2021-10-19 BASF Agro B.V. Plants having increased tolerance to herbicides
US11479786B2 (en) 2017-11-29 2022-10-25 Basf Se Plants having increased tolerance to herbicides
BE1029146B1 (fr) * 2021-02-26 2022-09-26 Xpress Biologics Procede de purification d'une proteine d'interet
CN117897378A (zh) 2021-09-03 2024-04-16 巴斯夫农业种子解决方案美国有限责任公司 对除草剂具有增加的耐受性的植物
WO2025038723A1 (en) 2023-08-14 2025-02-20 The Texas A&M University System Corn endotype-derived polypeptides capable of metabolizing fumonisin
WO2025153595A1 (en) 2024-01-17 2025-07-24 Basf Se Plants having increased tolerance to herbicides
WO2025153657A2 (en) 2024-01-17 2025-07-24 Basf Se Plants having increased tolerance to herbicides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022441A1 (en) 1992-04-23 1993-11-11 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Dna sequence of a plant resistance gene
AU1108295A (en) 1993-12-08 1995-06-27 Ciba-Geigy Ag Cytochrome p-450 monooxygenases

Also Published As

Publication number Publication date
EP0970191A2 (en) 2000-01-12
AU6727898A (en) 1998-09-29
JP2001514515A (ja) 2001-09-11
PL335643A1 (en) 2000-05-08
US6300544B1 (en) 2001-10-09
KR100583538B1 (ko) 2006-05-26
AU723454B2 (en) 2000-08-24
CA2282809A1 (en) 1998-09-17
KR20000076045A (ko) 2000-12-26

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: ROYAL VETERINARY AND AGRICULTURE UNIVERSITY (DK) ,

Free format text: TRANSFERIDO DE: NOVARTIS AG

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 10A E 11A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 1986 DE 27/03/2009.