BR9808140A - Formulação unitária - Google Patents
Formulação unitáriaInfo
- Publication number
- BR9808140A BR9808140A BR9808140-3A BR9808140A BR9808140A BR 9808140 A BR9808140 A BR 9808140A BR 9808140 A BR9808140 A BR 9808140A BR 9808140 A BR9808140 A BR 9808140A
- Authority
- BR
- Brazil
- Prior art keywords
- unit formulation
- formulation
- unit
- hydroxy
- derivative
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 229960004168 balsalazide Drugs 0.000 abstract 1
- JHDYSXXPQIFFJZ-UHFFFAOYSA-N chembl1834961 Chemical class C1=C(O)C(C(=O)O)=CC(N=NC=2C=CC=CC=2)=C1 JHDYSXXPQIFFJZ-UHFFFAOYSA-N 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- -1 sodium balsalazide dihydrate Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
<B>'FORMULAçãO UNITáRIA"<D>. A invenção proporciona uma formulação unitária que compreende um derivado de ácido 2-hidróxi-5-fenillazobenzóico, que é particularmente o dihidrato de balsalazida de sódio, cuja formulação apresenta uma densidade de pelo menos 0,9 g/mm³ e é utilizada no tratamento de doenças gastrointestinais.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9700934A SE9700934D0 (sv) | 1997-03-14 | 1997-03-14 | New formulation |
| PCT/SE1998/000455 WO1998041212A1 (en) | 1997-03-14 | 1998-03-13 | New formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9808140A true BR9808140A (pt) | 2000-03-28 |
Family
ID=20406161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9808140-3A BR9808140A (pt) | 1997-03-14 | 1998-03-13 | Formulação unitária |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6197341B1 (pt) |
| EP (1) | EP1003524A1 (pt) |
| JP (1) | JP2001519782A (pt) |
| AU (1) | AU6430198A (pt) |
| BE (1) | BE1011837A5 (pt) |
| BR (1) | BR9808140A (pt) |
| CA (1) | CA2283297A1 (pt) |
| FR (1) | FR2760638A1 (pt) |
| GR (1) | GR980100096A (pt) |
| HU (1) | HUP0000850A3 (pt) |
| NL (1) | NL1008575C2 (pt) |
| NO (1) | NO994431D0 (pt) |
| PL (1) | PL335700A1 (pt) |
| SE (1) | SE9700934D0 (pt) |
| WO (1) | WO1998041212A1 (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9700934D0 (sv) * | 1997-03-14 | 1997-03-14 | Astra Ab | New formulation |
| AU2001285489A1 (en) * | 2000-08-29 | 2002-03-13 | Nobex Corporation | 5-ASA derivatives having anti-inflammatory and antibiotic activity and methods of treating diseases therewith |
| EP1642885B1 (en) * | 2000-08-29 | 2009-11-11 | Biocon Limited | Use of a pharmaceutical composition containing a para-aminophenyl acetic acid derivative for treating inflammatory conditions of the gastrointestinal tract |
| US8048924B2 (en) * | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
| MY140707A (en) * | 2002-02-28 | 2010-01-15 | Mitsubishi Tanabe Pharma Corp | Process for preparing a phenylalanine derivative and intermediates thereof |
| ES2571252T3 (es) | 2004-02-06 | 2016-05-24 | Pharmatel (R&D) Pty Ltd As Trustee For The Pharmatel (R & D) Trust | Uso de aminosalicilatos en el síndrome de intestino irritable con predominio de diarrea |
| CN1988897B (zh) * | 2004-05-28 | 2011-06-29 | 萨利克斯药物有限公司 | 巴柳氮在制备治疗因放射所引起的肠炎的药物的应用 |
| DE602005022175D1 (de) * | 2004-05-28 | 2010-08-19 | Salix Pharmaceuticals Inc | Prävention, behandlung und linderung strahlungsinduzierter enteritis |
| PL1773767T3 (pl) * | 2004-07-07 | 2016-07-29 | Biocon Ltd | Synteza azowo związanych związków immunoregulacyjnych |
| US7741359B2 (en) * | 2005-05-27 | 2010-06-22 | Antibe Therapeutics Inc. | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs |
| WO2006125293A1 (en) | 2005-05-27 | 2006-11-30 | Antibe Therapeutics Inc. | Derivatives of 4- or 5-aminosalicylic acid |
| US7498355B2 (en) | 2005-05-27 | 2009-03-03 | Antibe Therapeutics Inc. | Derivatives of 4- or 5-aminosalicylic acid |
| US20060270635A1 (en) * | 2005-05-27 | 2006-11-30 | Wallace John L | Derivatives of 4- or 5-aminosalicylic acid |
| NZ565974A (en) | 2005-08-24 | 2012-07-27 | Salix Pharmaceuticals Ltd | Balsalazide formulations and manufacture and use thereof |
| US8921344B2 (en) * | 2006-11-03 | 2014-12-30 | Salix Pharmaceuticals, Inc. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives |
| US7452872B2 (en) * | 2005-08-24 | 2008-11-18 | Salix Pharmaceuticals, Inc. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives |
| KR20090021346A (ko) * | 2006-06-06 | 2009-03-03 | 안티브 테라퓨틱스 인크. | 트리메부틴 및 n-데스메틸 트리메부틴 염 |
| AU2011245455A1 (en) | 2010-04-26 | 2012-11-15 | Salix Pharmaceuticals, Ltd. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives for the treatment of males |
| US12053447B2 (en) | 2019-06-25 | 2024-08-06 | NuBioPharma, LLC | Oral solution and powder to liquid compositions of balsalazide |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4045429A (en) | 1970-03-06 | 1977-08-30 | Pharmacia Aktiebolag | 4-(4-Hydroxy- or acetoxy-3-carbomethoxyphenylazo)-benzenesulphonyl chloride |
| BE791889A (fr) | 1971-11-26 | 1973-05-24 | Pharmacia Ab | Nouveaux derives de la pyridine |
| JPS57500432A (pt) * | 1980-03-20 | 1982-03-11 | ||
| US4412992A (en) | 1980-07-21 | 1983-11-01 | Biorex Laboratories Limited | 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith |
| GB2080796B (en) * | 1980-07-21 | 1983-10-12 | Biorex Laboratories Ltd | 2-hydroxy-5-phenylazobenzoic acid derivatives |
| SE9003296L (sv) * | 1990-10-16 | 1992-04-17 | Kabi Pharmacia Ab | Foerfarande foer att formulera laekemedel |
| US5316772A (en) * | 1990-12-19 | 1994-05-31 | Solvay & Cie, S.A. (Societe Anonyme) | Bilayered oral pharmaceutical composition with pH dependent release |
| US5498608A (en) * | 1994-01-07 | 1996-03-12 | Salix Pharmaceuticals | Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents |
| SE9700934D0 (sv) * | 1997-03-14 | 1997-03-14 | Astra Ab | New formulation |
-
1997
- 1997-03-14 SE SE9700934A patent/SE9700934D0/xx unknown
-
1998
- 1998-03-06 GR GR980100096A patent/GR980100096A/el unknown
- 1998-03-12 FR FR9803077A patent/FR2760638A1/fr not_active Withdrawn
- 1998-03-12 NL NL1008575A patent/NL1008575C2/nl not_active IP Right Cessation
- 1998-03-13 AU AU64301/98A patent/AU6430198A/en not_active Abandoned
- 1998-03-13 BR BR9808140-3A patent/BR9808140A/pt not_active IP Right Cessation
- 1998-03-13 BE BE9800201A patent/BE1011837A5/fr not_active IP Right Cessation
- 1998-03-13 EP EP98909944A patent/EP1003524A1/en not_active Withdrawn
- 1998-03-13 JP JP54042198A patent/JP2001519782A/ja active Pending
- 1998-03-13 WO PCT/SE1998/000455 patent/WO1998041212A1/en not_active Ceased
- 1998-03-13 HU HU00008500000850A patent/HUP0000850A3/hu unknown
- 1998-03-13 PL PL98335700A patent/PL335700A1/xx unknown
- 1998-03-13 CA CA002283297A patent/CA2283297A1/en not_active Abandoned
- 1998-05-14 US US09/068,823 patent/US6197341B1/en not_active Expired - Lifetime
-
1999
- 1999-09-13 NO NO994431A patent/NO994431D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6430198A (en) | 1998-10-12 |
| GR980100096A (el) | 1998-11-30 |
| FR2760638A1 (fr) | 1998-09-18 |
| HUP0000850A2 (hu) | 2000-09-28 |
| NO994431L (no) | 1999-09-13 |
| BE1011837A5 (fr) | 2000-02-01 |
| JP2001519782A (ja) | 2001-10-23 |
| HUP0000850A3 (en) | 2000-10-30 |
| NL1008575C2 (nl) | 1999-09-10 |
| US6197341B1 (en) | 2001-03-06 |
| NO994431D0 (no) | 1999-09-13 |
| PL335700A1 (en) | 2000-05-08 |
| SE9700934D0 (sv) | 1997-03-14 |
| WO1998041212A1 (en) | 1998-09-24 |
| CA2283297A1 (en) | 1998-09-24 |
| NL1008575A1 (nl) | 1998-09-15 |
| EP1003524A1 (en) | 2000-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A,5A,6A,7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1892 DE 10/04/2007. |