BR9709077A - Compostos inibindo metaloproteinase de matriz composição tendo atividade inibitória de metaloprotease de matriz processos para inibir atividade de metaloprotease de matriz e para tratar um mamífero - Google Patents
Compostos inibindo metaloproteinase de matriz composição tendo atividade inibitória de metaloprotease de matriz processos para inibir atividade de metaloprotease de matriz e para tratar um mamíferoInfo
- Publication number
- BR9709077A BR9709077A BR9709077A BR9709077A BR9709077A BR 9709077 A BR9709077 A BR 9709077A BR 9709077 A BR9709077 A BR 9709077A BR 9709077 A BR9709077 A BR 9709077A BR 9709077 A BR9709077 A BR 9709077A
- Authority
- BR
- Brazil
- Prior art keywords
- processes
- matrix
- matrix metalloprotease
- mammal
- treat
- Prior art date
Links
- 102000005741 Metalloproteases Human genes 0.000 title 2
- 108010006035 Metalloproteases Proteins 0.000 title 2
- 239000011159 matrix material Substances 0.000 title 2
- 241000124008 Mammalia Species 0.000 title 1
- 102000002274 Matrix Metalloproteinases Human genes 0.000 title 1
- 108010000684 Matrix Metalloproteinases Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64502896A | 1996-05-15 | 1996-05-15 | |
| PCT/US1997/007921 WO1997043245A1 (en) | 1996-05-15 | 1997-05-12 | Inhibition of matrix metalloproteases by acetylene containing compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9709077A true BR9709077A (pt) | 1999-08-03 |
Family
ID=24587368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9709077A BR9709077A (pt) | 1996-05-15 | 1997-05-12 | Compostos inibindo metaloproteinase de matriz composição tendo atividade inibitória de metaloprotease de matriz processos para inibir atividade de metaloprotease de matriz e para tratar um mamífero |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0912496A1 (pt) |
| JP (1) | JP3090957B2 (pt) |
| CN (1) | CN1139570C (pt) |
| AR (1) | AR007097A1 (pt) |
| AU (1) | AU710759B2 (pt) |
| BR (1) | BR9709077A (pt) |
| CA (1) | CA2253796C (pt) |
| CO (1) | CO5080759A1 (pt) |
| HN (1) | HN1997000088A (pt) |
| HR (1) | HRP970245B1 (pt) |
| ID (1) | ID16910A (pt) |
| PA (1) | PA8429301A1 (pt) |
| SV (1) | SV1997000035A (pt) |
| TN (1) | TNSN97084A1 (pt) |
| TW (1) | TW381079B (pt) |
| WO (1) | WO1997043245A1 (pt) |
| YU (1) | YU18697A (pt) |
| ZA (1) | ZA974031B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6288063B1 (en) | 1998-05-27 | 2001-09-11 | Bayer Corporation | Substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors |
| AR035478A1 (es) * | 1999-01-27 | 2004-06-02 | Wyeth Corp | Acido amida-hidroxamico, acido acetilenico, beta-sulfonamido y fosfinico como inhibidores de la tace, uso de los mismos para la manufactura de un medicamento y composicion farmaceutica que los contiene |
| US6326516B1 (en) | 1999-01-27 | 2001-12-04 | American Cyanamid Company | Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors |
| EP1031349A1 (en) * | 1999-02-25 | 2000-08-30 | Bayer Aktiengesellschaft | Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives for the treatment of cerebral diseases |
| US7141607B1 (en) | 2000-03-10 | 2006-11-28 | Insite Vision Incorporated | Methods and compositions for treating and inhibiting retinal neovascularization |
| HUE030114T2 (en) * | 2010-07-08 | 2017-04-28 | Kaken Pharma Co Ltd | N-hydroxyformamide derivatives and pharmaceutical compositions containing them |
| JP2017509665A (ja) | 2014-04-03 | 2017-04-06 | バイエル ファーマ アクチエンゲゼルシャフト | 気道疾患治療のための２，５−ジ置換されたシクロペンタンカルボン酸類 |
| US20170022171A1 (en) | 2014-04-03 | 2017-01-26 | Bayer Pharma Aktiengesellschaft | 2,5-disubstituted cyclopentanecarboxylic acids and their use |
| US20170119776A1 (en) | 2014-04-03 | 2017-05-04 | Bayer Pharma Aktiengesellschaft | Chiral 2,5-disubstituted cyclopentanecarboxylic acid derivatives and use thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3784701A (en) * | 1970-09-21 | 1974-01-08 | American Cyanamid Co | Compositions containing substituted benzoylpropionic acids and method of use to treat inflammation and pain |
| DE2112716A1 (de) * | 1971-03-17 | 1972-10-05 | Thomae Gmbh Dr K | Neue 4-(4-Biphenylyl)-4-oxobuttersaeuren,ihre Salze und ihre Ester |
| FR2378741A1 (fr) | 1977-02-01 | 1978-08-25 | Fabre Sa Pierre | Acides garyl goxo isovaleriques doues de proprietes antiphlogistiques et antalgiques |
| US5789434A (en) | 1994-11-15 | 1998-08-04 | Bayer Corporation | Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors |
| ZA974033B (en) | 1996-05-15 | 1998-02-19 | Bayer Ag | Substituted 4-arylbutyric acid derivatives as matrix metalloprotease inhibitors. |
-
1997
- 1997-05-09 HR HR970245A patent/HRP970245B1/xx not_active IP Right Cessation
- 1997-05-09 CO CO97025172A patent/CO5080759A1/es unknown
- 1997-05-09 ZA ZA9704031A patent/ZA974031B/xx unknown
- 1997-05-09 TN TNTNSN97084A patent/TNSN97084A1/fr unknown
- 1997-05-12 CA CA002253796A patent/CA2253796C/en not_active Expired - Fee Related
- 1997-05-12 JP JP09540980A patent/JP3090957B2/ja not_active Expired - Fee Related
- 1997-05-12 PA PA19978429301A patent/PA8429301A1/es unknown
- 1997-05-12 TW TW086106283A patent/TW381079B/zh not_active IP Right Cessation
- 1997-05-12 EP EP97923622A patent/EP0912496A1/en not_active Withdrawn
- 1997-05-12 AR ARP970101977A patent/AR007097A1/es unknown
- 1997-05-12 HN HN1997000088A patent/HN1997000088A/es unknown
- 1997-05-12 AU AU29386/97A patent/AU710759B2/en not_active Ceased
- 1997-05-12 WO PCT/US1997/007921 patent/WO1997043245A1/en not_active Ceased
- 1997-05-12 YU YU18697A patent/YU18697A/sr unknown
- 1997-05-12 BR BR9709077A patent/BR9709077A/pt not_active Application Discontinuation
- 1997-05-12 CN CNB971964564A patent/CN1139570C/zh not_active Expired - Fee Related
- 1997-05-12 SV SV1997000035A patent/SV1997000035A/es unknown
- 1997-05-14 ID IDP971606A patent/ID16910A/id unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ID16910A (id) | 1997-11-20 |
| JP3090957B2 (ja) | 2000-09-25 |
| JPH11511179A (ja) | 1999-09-28 |
| ZA974031B (en) | 1998-02-19 |
| CN1139570C (zh) | 2004-02-25 |
| CO5080759A1 (es) | 2001-09-25 |
| HRP970245A2 (en) | 1998-04-30 |
| AU710759B2 (en) | 1999-09-30 |
| TNSN97084A1 (fr) | 2005-03-15 |
| TW381079B (en) | 2000-02-01 |
| CA2253796A1 (en) | 1997-11-20 |
| WO1997043245A1 (en) | 1997-11-20 |
| CA2253796C (en) | 2003-10-28 |
| YU18697A (en) | 1999-11-22 |
| SV1997000035A (es) | 1999-01-14 |
| PA8429301A1 (es) | 2000-05-24 |
| HN1997000088A (es) | 1997-06-18 |
| CN1225623A (zh) | 1999-08-11 |
| AU2938697A (en) | 1997-12-05 |
| HRP970245B1 (en) | 2002-06-30 |
| AR007097A1 (es) | 1999-10-13 |
| EP0912496A1 (en) | 1999-05-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB36 | Technical and formal requirements: requirement - article 36 of industrial property law | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |