BR9707624A - '' poducao de acidos graxos hidroxilados em plantas modificadas geneticamente '' - Google Patents
'' poducao de acidos graxos hidroxilados em plantas modificadas geneticamente ''Info
- Publication number
- BR9707624A BR9707624A BR9707624-4A BR9707624A BR9707624A BR 9707624 A BR9707624 A BR 9707624A BR 9707624 A BR9707624 A BR 9707624A BR 9707624 A BR9707624 A BR 9707624A
- Authority
- BR
- Brazil
- Prior art keywords
- fatty acid
- genetically modified
- modified plants
- hydroxylated fatty
- acid production
- Prior art date
Links
- 235000014113 dietary fatty acids Nutrition 0.000 title abstract 4
- 229930195729 fatty acid Natural products 0.000 title abstract 4
- 239000000194 fatty acid Substances 0.000 title abstract 4
- 150000004665 fatty acids Chemical class 0.000 title abstract 3
- 102100027297 Fatty acid 2-hydroxylase Human genes 0.000 abstract 2
- 101000937693 Homo sapiens Fatty acid 2-hydroxylase Proteins 0.000 abstract 2
- 102000008109 Mixed Function Oxygenases Human genes 0.000 abstract 2
- 108010074633 Mixed Function Oxygenases Proteins 0.000 abstract 2
- 230000009261 transgenic effect Effects 0.000 abstract 2
- 108010087894 Fatty acid desaturases Proteins 0.000 abstract 1
- 102000009114 Fatty acid desaturases Human genes 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- -1 fatty acid lipid Chemical class 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8222—Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0073—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.14.13
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fats And Perfumes (AREA)
Abstract
"PRODUçãO DE áCIDOS GRAXOS HIDROXILADOS EM PLANTAS MODIFICADAS GENETICAMENTE". Esta invenção se refere a hidroxilases de ácido graxo. Processos para usar sequências de aminoácidos ou nucleotídeos conservados para obter hidroxilases de ácido graxo são descritos. Também é descrito o uso de clones de cDNA codificando uma hidroxilase de planta para produzir uma família de ácidos graxos hidroxilados em plantas transgênicas. Adicionalmente, o uso de genes codificando hidroxilases ou desaturases de ácidos graxos para alterar o nível de insaturação de lipídeos de ácidos graxos em plantas transgênicas é descrito.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/597,313 US6310194B1 (en) | 1994-09-26 | 1996-02-06 | Plant fatty acid hydroxylases |
| PCT/US1997/002187 WO1997030582A1 (en) | 1996-02-06 | 1997-02-06 | Production of hydroxylated fatty acids in genetically modified plants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9707624A true BR9707624A (pt) | 2000-01-04 |
Family
ID=24390991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9707624-4A BR9707624A (pt) | 1996-02-06 | 1997-02-06 | '' poducao de acidos graxos hidroxilados em plantas modificadas geneticamente '' |
Country Status (7)
| Country | Link |
|---|---|
| US (6) | US6310194B1 (pt) |
| EP (1) | EP1009220A1 (pt) |
| JP (1) | JP2000506006A (pt) |
| AU (1) | AU723161B2 (pt) |
| BR (1) | BR9707624A (pt) |
| CA (1) | CA2242859A1 (pt) |
| WO (1) | WO1997030582A1 (pt) |
Families Citing this family (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6310194B1 (en) * | 1994-09-26 | 2001-10-30 | Carnegie Institution Of Washington | Plant fatty acid hydroxylases |
| US5965793A (en) * | 1995-09-20 | 1999-10-12 | Monsanto Company, Inc. | Strong early seed-specific gene regulatory region |
| US7109392B1 (en) | 1996-10-09 | 2006-09-19 | Cargill, Incorporated | Methods for increasing oleic acid content in seeds from transgenic plants containing a mutant delta 12 desaturase |
| US6075183A (en) * | 1997-04-11 | 2000-06-13 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants |
| CN1253588A (zh) * | 1997-04-11 | 2000-05-17 | 艾博特公司 | 在植物中合成长链多不饱和脂肪酸的方法和组合物 |
| US7745694B1 (en) | 1997-04-11 | 2010-06-29 | Monsanto Technology Llc | Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants |
| US6051754A (en) * | 1997-04-11 | 2000-04-18 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants |
| US5968809A (en) * | 1997-04-11 | 1999-10-19 | Abbot Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| AU761152B2 (en) * | 1998-03-17 | 2003-05-29 | Cargill Incorporated | Genes for mutant microsomal delta-12 fatty acid desaturases and related enzymes from plants |
| EP1071785A2 (en) * | 1998-04-16 | 2001-01-31 | Pierre Broun | Interconversion of plant fatty acid desaturases and hydroxylases |
| PT1086236E (pt) | 1998-06-12 | 2007-12-12 | Calgene Llc | Ácidos gordos poliinsaturados em plantas |
| US6323392B1 (en) * | 1999-03-01 | 2001-11-27 | Pioneer Hi-Bred International, Inc. | Formation of brassica napus F1 hybrid seeds which exhibit a highly elevated oleic acid content and a reduced linolenic acid content in the endogenously formed oil of the seeds |
| IT1312109B1 (it) * | 1999-05-18 | 2002-04-04 | Metapontum Agrobios S C R L | Gene isolato da ricinus communis che codifica per una nuova proteinache interagisce con l'enzima oleato 12-idrossilasi |
| IL146782A0 (en) | 1999-06-07 | 2002-07-25 | Basf Plant Science Gmbh | 6-acetylenase and 6-desaturase from ceratodon purpureus |
| FR2794772B1 (fr) * | 1999-06-10 | 2001-09-21 | Agronomique Inst Nat Rech | Promoteur permettant l'expression de transgenes dans toute la plante hormis dans la graine |
| DE10030976A1 (de) | 2000-06-30 | 2002-01-10 | Basf Ag | DELTA6-Desaturasegene exprimierende Pflanzen und PUFAS enthaltende Öle aus diesen Pflanzen und ein Verfahren zur Herstellung ungesättigter Fettsäuren |
| DE60028053T2 (de) * | 1999-08-27 | 2006-12-21 | SemBioSys Genetics, Inc., Calgary | Samenspezifischer promoter aus flachs (linum usitatissimum) |
| DE10102337A1 (de) | 2001-01-19 | 2002-07-25 | Basf Plant Science Gmbh | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte |
| WO2003060092A2 (en) * | 2002-01-14 | 2003-07-24 | Brookhaven Science Associates, Llc | Modified fatty acid hydroxylase protein and genes |
| DE50312241D1 (de) | 2002-01-30 | 2010-01-28 | Basf Plant Science Gmbh | Verfahren zur herstellung mehrfach ungesättigter f |
| GB2385852A (en) | 2002-02-27 | 2003-09-03 | Rothamsted Ex Station | Delta 6-desaturases from Primulaceae |
| US6887900B2 (en) * | 2002-03-04 | 2005-05-03 | Divergence, Inc. | Nematicidal compositions and methods |
| US20040157803A1 (en) * | 2002-03-04 | 2004-08-12 | Williams Deryck J. | Nematicidal fatty acid and fatty acid ester related compounds |
| DE10219203A1 (de) | 2002-04-29 | 2003-11-13 | Basf Plant Science Gmbh | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen |
| CA2510462A1 (en) | 2002-12-19 | 2004-07-08 | University Of Bristol | Method for producing polyunsaturated fatty acids in a transgenic plant or microorganism comprising an introduced delta-9-elongase and a delta-8-desaturase |
| BRPI0407296A (pt) * | 2003-02-05 | 2006-03-07 | Divergence Inc | ácidos nucléicos que codificam agentes antelmìnticos e plantas produzidas a partir deles |
| BRPI0407138A (pt) | 2003-02-27 | 2006-01-10 | Basf Plant Science Gmbh | Sequência de ácido nucleico isolada, sequência de aminoácido, construção de gene, vetor, organismo transgênico não humano, processo para produzir ácidos graxos poliinsaturados, óleo, lipìdeo, ou um ácido graxo poliinsaturado ou uma fração dos mesmos, composições de óleo, de lipìdeos, ou de ácido graxo, e, uso do óleo, lipìdeos ou ácidos graxos ou de composições de óleo, de lipìdeos ou de ácido graxo |
| WO2004087902A2 (de) | 2003-03-31 | 2004-10-14 | University Of Bristol | Neue pflanzliche acyltransferasen spezifisch für langkettige mehrfach ungesättigte fettsäuren |
| WO2004090123A2 (de) | 2003-04-08 | 2004-10-21 | Basf Plant Science Gmbh | Δ-4-desaturasen aus euglena gracilis, exprimierende pflanzen und pufa enthaltende öle |
| US7554007B2 (en) | 2003-05-22 | 2009-06-30 | Evogene Ltd. | Methods of increasing abiotic stress tolerance and/or biomass in plants |
| AU2005234725B2 (en) * | 2003-05-22 | 2012-02-23 | Evogene Ltd. | Methods of Increasing Abiotic Stress Tolerance and/or Biomass in Plants and Plants Generated Thereby |
| US11952581B2 (en) | 2003-08-01 | 2024-04-09 | Basf Plant Science Gmbh | Process for the production of polyunsaturated fatty acids in transgenic organisms |
| ES2590077T3 (es) | 2003-08-01 | 2016-11-18 | Basf Plant Science Gmbh | Procedimiento para la producción de ácidos grasos poliinsaturados en organismos transgénicos |
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-
1996
- 1996-02-06 US US08/597,313 patent/US6310194B1/en not_active Expired - Lifetime
-
1997
- 1997-02-06 EP EP97908648A patent/EP1009220A1/en not_active Withdrawn
- 1997-02-06 WO PCT/US1997/002187 patent/WO1997030582A1/en not_active Ceased
- 1997-02-06 AU AU20504/97A patent/AU723161B2/en not_active Ceased
- 1997-02-06 BR BR9707624-4A patent/BR9707624A/pt not_active Application Discontinuation
- 1997-02-06 CA CA002242859A patent/CA2242859A1/en not_active Abandoned
- 1997-02-06 JP JP9530216A patent/JP2000506006A/ja active Pending
-
2001
- 2001-06-21 US US09/885,189 patent/US6936728B2/en not_active Expired - Fee Related
-
2004
- 2004-04-08 US US10/820,202 patent/US20040237139A1/en not_active Abandoned
-
2005
- 2005-02-16 US US11/058,746 patent/US20060101543A1/en not_active Abandoned
-
2007
- 2007-09-27 US US11/905,067 patent/US8003855B2/en not_active Expired - Fee Related
-
2009
- 2009-07-15 US US12/503,705 patent/US20100168455A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20040237139A1 (en) | 2004-11-25 |
| US6310194B1 (en) | 2001-10-30 |
| WO1997030582A1 (en) | 1997-08-28 |
| AU2050497A (en) | 1997-09-10 |
| EP1009220A4 (en) | 2000-06-21 |
| US20060101543A1 (en) | 2006-05-11 |
| AU723161B2 (en) | 2000-08-17 |
| US20020151699A1 (en) | 2002-10-17 |
| US8003855B2 (en) | 2011-08-23 |
| US6936728B2 (en) | 2005-08-30 |
| US20090070902A1 (en) | 2009-03-12 |
| CA2242859A1 (en) | 1997-08-28 |
| EP1009220A1 (en) | 2000-06-21 |
| US20100168455A1 (en) | 2010-07-01 |
| JP2000506006A (ja) | 2000-05-23 |
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| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: O DEPOSITANTE DEIXOU DE APRESENTAR MANIFESTACAO SOBRE O PARECER NEGATIVO, ASSIM, DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. |