BR9612974B8 - Para-herquamidas e marcfortinas antiparasíticas. - Google Patents
Para-herquamidas e marcfortinas antiparasíticas.Info
- Publication number
- BR9612974B8 BR9612974B8 BRPI9612974-3B8A BR9612974A BR9612974B8 BR 9612974 B8 BR9612974 B8 BR 9612974B8 BR 9612974 A BR9612974 A BR 9612974A BR 9612974 B8 BR9612974 B8 BR 9612974B8
- Authority
- BR
- Brazil
- Prior art keywords
- marcfortines
- antiparasitic
- parameters
- antiparasitic parameters
- Prior art date
Links
- 229930188848 Marcfortine Natural products 0.000 title 1
- 230000002141 anti-parasite Effects 0.000 title 1
- 239000003096 antiparasitic agent Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Agronomy & Crop Science (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Epoxy Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Percussion Or Vibration Massage (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US132495P | 1995-07-21 | 1995-07-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9612974B8 true BR9612974B8 (pt) | 2014-10-29 |
Family
ID=21695455
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI9612975-1B8A BR9612975B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas e marcfortinas antiparasíticas. |
| BRPI9612974-3B8A BR9612974B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas e marcfortinas antiparasíticas. |
| BRPI9612973-5B8A BR9612973B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas e marcfortinas antiparasíticas. |
| BRPI9612944-1B8A BR9612944B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas antiparasíticas. |
| BRPI9612972-7B8A BR9612972B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas e marcfortinas antiparasíticas. |
| BRPI9609812-0B8A BR9609812B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas e marcfortinas antiparasíticas. |
| BRPI9612963-8B8A BR9612963B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas e marcfortinas antiparasíticas. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI9612975-1B8A BR9612975B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas e marcfortinas antiparasíticas. |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI9612973-5B8A BR9612973B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas e marcfortinas antiparasíticas. |
| BRPI9612944-1B8A BR9612944B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas antiparasíticas. |
| BRPI9612972-7B8A BR9612972B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas e marcfortinas antiparasíticas. |
| BRPI9609812-0B8A BR9609812B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas e marcfortinas antiparasíticas. |
| BRPI9612963-8B8A BR9612963B8 (pt) | 1995-07-21 | 1996-06-26 | Para-herquamidas e marcfortinas antiparasíticas. |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US5703078A (pt) |
| EP (3) | EP1400523A3 (pt) |
| JP (2) | JP4122447B2 (pt) |
| KR (1) | KR100428335B1 (pt) |
| CN (2) | CN1125824C (pt) |
| AR (10) | AR003466A1 (pt) |
| AT (1) | ATE311390T1 (pt) |
| AU (1) | AU699644B2 (pt) |
| BR (7) | BR9612975B8 (pt) |
| CA (1) | CA2225813C (pt) |
| CO (1) | CO4750664A1 (pt) |
| CZ (1) | CZ296008B6 (pt) |
| DE (1) | DE69635524T2 (pt) |
| DK (2) | DK0871631T3 (pt) |
| ES (2) | ES2249783T3 (pt) |
| FI (2) | FI115912B (pt) |
| HU (1) | HU226296B1 (pt) |
| ID (1) | ID30373A (pt) |
| MX (1) | MX9800625A (pt) |
| MY (1) | MY113806A (pt) |
| NO (1) | NO324287B1 (pt) |
| NZ (1) | NZ311952A (pt) |
| PL (1) | PL185007B1 (pt) |
| PT (1) | PT1489082E (pt) |
| RU (1) | RU2162090C2 (pt) |
| SI (1) | SI0871631T1 (pt) |
| SK (2) | SK284833B6 (pt) |
| TW (1) | TW334436B (pt) |
| WO (1) | WO1997003988A1 (pt) |
| ZA (1) | ZA965908B (pt) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA976761B (en) * | 1996-09-09 | 1999-01-29 | Upjohn Co | 25 Methylene and 24,25-epoxy marcfortines and paraherquamides |
| WO1998021211A1 (en) * | 1996-11-15 | 1998-05-22 | Pharmacia & Upjohn Company | 1- and 2-substituted marcfortines and paraherquamides as antiparasitic agents |
| PE20011289A1 (es) * | 2000-04-07 | 2001-12-21 | Upjohn Co | Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles |
| BRPI0921546A8 (pt) | 2008-11-14 | 2022-08-16 | Merial Ltd | Compostos de arilazol-2-il cianoetilamina enriquecidos enantiomericamente, método para fabricação e método de uso dos mesmos |
| NZ592865A (en) | 2008-11-19 | 2013-08-30 | Merial Ltd | Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof |
| ES2537424T3 (es) | 2008-12-04 | 2015-06-08 | Merial Limited | Derivados de dímeros de avermectina y de milbemicina |
| EP2314292A1 (en) | 2009-10-20 | 2011-04-27 | Novartis AG | Endoparasiticidal compositions |
| AU2010325827B2 (en) | 2009-12-04 | 2015-11-05 | Basf Se | Pesticidal bis-organosulfur compounds |
| AU2010330844B2 (en) | 2009-12-17 | 2014-11-27 | Boehringer Ingelheim Animal Health USA Inc. | Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles |
| MX336189B (es) | 2009-12-17 | 2016-01-11 | Merial Ltd | Compuesto de dihidroazol antiparasiticos y composiciones qe¡ue comprenden los mismos. |
| UA108641C2 (uk) | 2010-04-02 | 2015-05-25 | Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування | |
| EP2640728B1 (en) | 2010-11-16 | 2016-09-07 | Merial, Inc. | Novel monensin derivatives for the treatment and prevention of protozoal infections |
| EP2723716B1 (en) | 2011-06-27 | 2017-01-11 | Merial, Inc. | Amido-pyridyl ether compounds and compositions and their use against parasites |
| WO2013003168A1 (en) | 2011-06-27 | 2013-01-03 | Merial Limited | Novel insect-repellent coumarin derivatives, syntheses, and methods of use |
| CN106474120B (zh) | 2011-09-12 | 2020-07-28 | 勃林格殷格翰动物保健美国公司 | 包含异噁唑啉活性剂的杀寄生物组合物,其方法和用途 |
| US20130079394A1 (en) | 2011-09-23 | 2013-03-28 | Cnrs (Centre National Recherche Scientifique) | Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods |
| CA2855954C (en) | 2011-11-17 | 2020-09-01 | Merial Limited | Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof. |
| HUE067125T2 (hu) | 2011-12-02 | 2024-10-28 | Boehringer Ingelheim Vetmedica Gmbh | Hosszú hatású injektálható moxidektin formulációk |
| TR201909461T4 (tr) | 2012-02-06 | 2019-07-22 | Boehringer Ingelheim Animal Health Usa Inc | Si̇stemi̇k olarak etki̇ eden akti̇f maddeleri̇ i̇çeren parazi̇ti̇si̇dal oral veteri̇nerli̇ğe ai̇t bi̇leşi̇mler, bunlarin yöntemleri̇ ve kullanimlari |
| JO3626B1 (ar) | 2012-02-23 | 2020-08-27 | Merial Inc | تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها |
| NZ701185A (en) | 2012-04-20 | 2015-08-28 | Merial Ltd | Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof |
| JP5737255B2 (ja) * | 2012-09-27 | 2015-06-17 | ダイキン工業株式会社 | チオノカルボン酸エステルの製造方法 |
| NZ716598A (en) | 2012-11-20 | 2017-02-24 | Merial Inc | Anthelmintic compounds and compositions and method of using thereof |
| EA030935B1 (ru) | 2013-11-01 | 2018-10-31 | Мериал, Инк. | Антипаразитарные и пестицидные изоксазолиновые соединения |
| CA2945766C (en) | 2014-04-17 | 2023-09-26 | Merial, Inc. | Use of malononitrile compounds for protecting animals from parasites |
| CA2949511A1 (en) | 2014-05-19 | 2015-11-26 | Merial, Inc. | Anthelmintic compounds |
| BR112016029888B1 (pt) | 2014-06-19 | 2021-05-18 | Merial, Inc | composições parasiticidas compreendendo derivados de indol, métodos e usos dos mesmos |
| AU2015339096B2 (en) | 2014-10-31 | 2018-08-02 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal composition comprising fipronil |
| UY36570A (es) | 2015-02-26 | 2016-10-31 | Merial Inc | Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas |
| WO2016187534A1 (en) | 2015-05-20 | 2016-11-24 | Merial, Inc. | Anthelmintic depsipeptide compounds |
| UY37137A (es) | 2016-02-24 | 2017-09-29 | Merial Inc | Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos |
| WO2018039508A1 (en) | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
| AU2017344097A1 (en) | 2016-10-14 | 2019-05-02 | Boehringer Ingelheim Animal Health USA Inc. | Pesticidal and parasiticidal vinyl isoxazoline compounds |
| WO2018093920A1 (en) | 2016-11-16 | 2018-05-24 | Merial, Inc. | Anthelmintic depsipeptide compounds |
| BR112020003217A2 (pt) | 2017-08-14 | 2020-10-06 | Boehringer Ingelheim Animal Health USA Inc. | compostos pesticidas e parasiticidas de pirazolisoxazolina |
| WO2019157241A1 (en) | 2018-02-08 | 2019-08-15 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof |
| BR112021000257A2 (pt) | 2018-07-09 | 2021-04-06 | Boehringer Ingelheim Animal Health USA Inc. | Compostos heterocíclicos anti-helmínticos |
| US11773066B2 (en) | 2018-11-20 | 2023-10-03 | Boehringer Ingelheim Animal Health USA Inc. | Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof |
| AU2020231319A1 (en) | 2019-03-01 | 2021-10-21 | Boehringer Ingelheim Animal Health USA Inc. | Injectable clorsulon compositions, methods and uses thereof |
| US11560388B2 (en) | 2019-03-19 | 2023-01-24 | Boehringer Ingelheim Vetmedica Gmbh | Anthelmintic aza-benzothiophene and aza-benzofuran compounds |
| EP4185589A1 (en) | 2020-05-29 | 2023-05-31 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic heterocyclic compounds |
| CN111748503B (zh) * | 2020-08-04 | 2021-12-14 | 华中农业大学 | 一种深海独岛枝芽胞杆菌培养基和剂型 |
| EP4262789A1 (en) | 2020-12-21 | 2023-10-25 | Boehringer Ingelheim Vetmedica GmbH | Parasiticidal collar comprising isoxazoline compounds |
| JP2025507585A (ja) | 2022-02-17 | 2025-03-21 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | 流体製品メーラーを提供する方法及びシステム |
| WO2025257633A1 (en) | 2024-06-12 | 2025-12-18 | Boehringer Ingelheim Vetmedica Gmbh | Long-acting castor oil-containing injectable formulations and methods of use thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5075307A (en) * | 1987-07-28 | 1991-12-24 | Merck & Co., Inc. | Paraherquamide and dihydroparaherquamide as antihelminthic agents |
| US4873247A (en) * | 1987-11-27 | 1989-10-10 | Goegelman Robert T | Derivatives of paraherquamide isolated from a fermentation broth active as antiparasitic agents |
| US4978656A (en) * | 1988-08-12 | 1990-12-18 | Merck & Co., Inc. | Synthetic derivatives of paraherquamide |
| US4866060A (en) * | 1988-08-19 | 1989-09-12 | Merck & Co., Inc. | Use of the natural product marcfortines as antiparasitic agents |
| US4923867A (en) * | 1988-08-24 | 1990-05-08 | Merck & Co., Inc. | Synthetic marcfortine derivatives useful as antiparasitic agents |
| NZ233043A (en) * | 1989-03-30 | 1992-09-25 | Merck & Co Inc | Anthelmintic heterocyclic compounds prepared by action of cunninghamella blakesleeana on (dihydro)paraherquamide |
| IE904606A1 (en) * | 1989-12-21 | 1991-07-03 | Beecham Group Plc | Novel products |
| GB9014194D0 (en) * | 1990-06-26 | 1990-08-15 | Pfizer Ltd | Antiparasitic agents |
| WO1992022555A1 (en) * | 1991-06-17 | 1992-12-23 | Beecham Group Plc | Paraherquamide derivatives, precursor thereof, processes for their preparation, microorganism used and their use as antiparasitic agents |
| TW410227B (en) * | 1993-06-16 | 2000-11-01 | Upjohn Co | 14-substituted marcfortines and derivatives useful as antiparasitic agents |
-
1996
- 1996-06-04 TW TW085106656A patent/TW334436B/zh not_active IP Right Cessation
- 1996-06-04 MY MYPI96002158A patent/MY113806A/en unknown
- 1996-06-26 MX MX9800625A patent/MX9800625A/es unknown
- 1996-06-26 ES ES96922529T patent/ES2249783T3/es not_active Expired - Lifetime
- 1996-06-26 BR BRPI9612975-1B8A patent/BR9612975B8/pt not_active IP Right Cessation
- 1996-06-26 PL PL96324574A patent/PL185007B1/pl unknown
- 1996-06-26 WO PCT/US1996/010686 patent/WO1997003988A1/en not_active Ceased
- 1996-06-26 BR BRPI9612974-3B8A patent/BR9612974B8/pt not_active IP Right Cessation
- 1996-06-26 SI SI9630723T patent/SI0871631T1/sl unknown
- 1996-06-26 SK SK54-98A patent/SK284833B6/sk not_active IP Right Cessation
- 1996-06-26 CN CN96195723A patent/CN1125824C/zh not_active Expired - Fee Related
- 1996-06-26 CZ CZ1998110A patent/CZ296008B6/cs not_active IP Right Cessation
- 1996-06-26 KR KR10-1998-0700418A patent/KR100428335B1/ko not_active Expired - Fee Related
- 1996-06-26 PT PT40226383T patent/PT1489082E/pt unknown
- 1996-06-26 EP EP03023859A patent/EP1400523A3/en not_active Withdrawn
- 1996-06-26 CN CNB03158991XA patent/CN1277830C/zh not_active Expired - Lifetime
- 1996-06-26 HU HU9802221A patent/HU226296B1/hu not_active IP Right Cessation
- 1996-06-26 CA CA002225813A patent/CA2225813C/en not_active Expired - Lifetime
- 1996-06-26 BR BRPI9612973-5B8A patent/BR9612973B8/pt not_active IP Right Cessation
- 1996-06-26 AU AU63373/96A patent/AU699644B2/en not_active Expired
- 1996-06-26 SK SK5057-2005A patent/SK285248B6/sk not_active IP Right Cessation
- 1996-06-26 BR BRPI9612944-1B8A patent/BR9612944B8/pt not_active IP Right Cessation
- 1996-06-26 DE DE69635524T patent/DE69635524T2/de not_active Expired - Lifetime
- 1996-06-26 BR BRPI9612972-7B8A patent/BR9612972B8/pt not_active IP Right Cessation
- 1996-06-26 BR BRPI9609812-0B8A patent/BR9609812B8/pt not_active IP Right Cessation
- 1996-06-26 AT AT96922529T patent/ATE311390T1/de active
- 1996-06-26 DK DK96922529T patent/DK0871631T3/da active
- 1996-06-26 ES ES04022638.3T patent/ES2439569T3/es not_active Expired - Lifetime
- 1996-06-26 EP EP04022638.3A patent/EP1489082B1/en not_active Expired - Lifetime
- 1996-06-26 RU RU98103337/04A patent/RU2162090C2/ru active
- 1996-06-26 JP JP50667697A patent/JP4122447B2/ja not_active Expired - Fee Related
- 1996-06-26 DK DK04022638.3T patent/DK1489082T3/da active
- 1996-06-26 NZ NZ311952A patent/NZ311952A/xx not_active IP Right Cessation
- 1996-06-26 EP EP96922529A patent/EP0871631B1/en not_active Expired - Lifetime
- 1996-06-26 BR BRPI9612963-8B8A patent/BR9612963B8/pt not_active IP Right Cessation
- 1996-06-27 US US08/670,306 patent/US5703078A/en not_active Expired - Lifetime
- 1996-07-11 ZA ZA9605908A patent/ZA965908B/xx unknown
- 1996-07-19 CO CO96038153A patent/CO4750664A1/es unknown
- 1996-07-19 AR ARP960103674A patent/AR003466A1/es active IP Right Grant
- 1996-07-22 ID IDP00200100831A patent/ID30373A/id unknown
-
1997
- 1997-03-21 US US08/822,419 patent/US5750695A/en not_active Expired - Lifetime
-
1998
- 1998-01-20 NO NO19980255A patent/NO324287B1/no not_active IP Right Cessation
- 1998-01-20 FI FI980112A patent/FI115912B/fi not_active IP Right Cessation
-
2003
- 2003-02-13 AR ARP030100485A patent/AR038431A2/es active IP Right Grant
- 2003-02-13 AR ARP030100481A patent/AR038427A2/es active IP Right Grant
- 2003-02-13 AR ARP030100482A patent/AR038428A2/es active IP Right Grant
- 2003-02-13 AR ARP030100486A patent/AR038432A2/es active IP Right Grant
- 2003-02-13 AR ARP030100483A patent/AR038429A2/es active IP Right Grant
- 2003-02-13 AR ARP030100484A patent/AR038430A2/es active IP Right Grant
- 2003-02-13 AR ARP030100488A patent/AR038434A2/es active IP Right Grant
- 2003-02-13 AR ARP030100487A patent/AR038433A2/es active IP Right Grant
-
2005
- 2005-03-04 FI FI20050238A patent/FI118471B/fi not_active IP Right Cessation
-
2006
- 2006-02-10 AR ARP060100487A patent/AR052907A1/es not_active Application Discontinuation
-
2007
- 2007-08-22 JP JP2007216098A patent/JP2008007516A/ja active Pending
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