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AR038431A2 - Derivados 2-desoxo-15-alquilo de marcfortina - Google Patents

Derivados 2-desoxo-15-alquilo de marcfortina

Info

Publication number
AR038431A2
AR038431A2 ARP030100485A ARP030100485A AR038431A2 AR 038431 A2 AR038431 A2 AR 038431A2 AR P030100485 A ARP030100485 A AR P030100485A AR P030100485 A ARP030100485 A AR P030100485A AR 038431 A2 AR038431 A2 AR 038431A2
Authority
AR
Argentina
Prior art keywords
marcfortina
desoxo
rent
derivatives
alkyl
Prior art date
Application number
ARP030100485A
Other languages
English (en)
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21695455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR038431(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of AR038431A2 publication Critical patent/AR038431A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Percussion Or Vibration Massage (AREA)

Abstract

Compuestos de 2-desoxo-15-alquilo de la fórmula (1) en donde R14 es -H ó alquilo C1-4 y en donde R15 es -H ó alquilo C1-4, sus óxidos y sus sales farmacéuticamente aceptables.
ARP030100485A 1995-07-21 2003-02-13 Derivados 2-desoxo-15-alquilo de marcfortina AR038431A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US132495P 1995-07-21 1995-07-21

Publications (1)

Publication Number Publication Date
AR038431A2 true AR038431A2 (es) 2005-01-12

Family

ID=21695455

Family Applications (10)

Application Number Title Priority Date Filing Date
ARP960103674A AR003466A1 (es) 1995-07-21 1996-07-19 Compuestos 14-hidroxi-2-desoxoparahercuamida b
ARP030100485A AR038431A2 (es) 1995-07-21 2003-02-13 Derivados 2-desoxo-15-alquilo de marcfortina
ARP030100481A AR038427A2 (es) 1995-07-21 2003-02-13 Compuestos 15-alquil-14-hidroxilo de marcfortina y parahercuamida
ARP030100482A AR038428A2 (es) 1995-07-21 2003-02-13 Compuestos fluorados de marcfortina
ARP030100486A AR038432A2 (es) 1995-07-21 2003-02-13 Derivados 1,2-dihidro de parahercuamida y marcfortina
ARP030100483A AR038429A2 (es) 1995-07-21 2003-02-13 Compuestos 15-alquil-16-hidroxilo de marcfortina
ARP030100484A AR038430A2 (es) 1995-07-21 2003-02-13 Derivados de parahercuamida b
ARP030100488A AR038434A2 (es) 1995-07-21 2003-02-13 Compuesto 14,15-dihidro-16-oxoparahercuamida y compuestos 2-desoxo de parahercuamida y marcfortina
ARP030100487A AR038433A2 (es) 1995-07-21 2003-02-13 Derivados 2-alquil-2-desoxo de parahercuamida y marcfortina
ARP060100487A AR052907A1 (es) 1995-07-21 2006-02-10 Compuesto 14,15-deshidro-16-oxoparahercuamida y compuestos 2- desoxo de parahercuamida y marcfortina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP960103674A AR003466A1 (es) 1995-07-21 1996-07-19 Compuestos 14-hidroxi-2-desoxoparahercuamida b

Family Applications After (8)

Application Number Title Priority Date Filing Date
ARP030100481A AR038427A2 (es) 1995-07-21 2003-02-13 Compuestos 15-alquil-14-hidroxilo de marcfortina y parahercuamida
ARP030100482A AR038428A2 (es) 1995-07-21 2003-02-13 Compuestos fluorados de marcfortina
ARP030100486A AR038432A2 (es) 1995-07-21 2003-02-13 Derivados 1,2-dihidro de parahercuamida y marcfortina
ARP030100483A AR038429A2 (es) 1995-07-21 2003-02-13 Compuestos 15-alquil-16-hidroxilo de marcfortina
ARP030100484A AR038430A2 (es) 1995-07-21 2003-02-13 Derivados de parahercuamida b
ARP030100488A AR038434A2 (es) 1995-07-21 2003-02-13 Compuesto 14,15-dihidro-16-oxoparahercuamida y compuestos 2-desoxo de parahercuamida y marcfortina
ARP030100487A AR038433A2 (es) 1995-07-21 2003-02-13 Derivados 2-alquil-2-desoxo de parahercuamida y marcfortina
ARP060100487A AR052907A1 (es) 1995-07-21 2006-02-10 Compuesto 14,15-deshidro-16-oxoparahercuamida y compuestos 2- desoxo de parahercuamida y marcfortina

Country Status (30)

Country Link
US (2) US5703078A (es)
EP (3) EP1400523A3 (es)
JP (2) JP4122447B2 (es)
KR (1) KR100428335B1 (es)
CN (2) CN1125824C (es)
AR (10) AR003466A1 (es)
AT (1) ATE311390T1 (es)
AU (1) AU699644B2 (es)
BR (7) BR9612975B8 (es)
CA (1) CA2225813C (es)
CO (1) CO4750664A1 (es)
CZ (1) CZ296008B6 (es)
DE (1) DE69635524T2 (es)
DK (2) DK0871631T3 (es)
ES (2) ES2249783T3 (es)
FI (2) FI115912B (es)
HU (1) HU226296B1 (es)
ID (1) ID30373A (es)
MX (1) MX9800625A (es)
MY (1) MY113806A (es)
NO (1) NO324287B1 (es)
NZ (1) NZ311952A (es)
PL (1) PL185007B1 (es)
PT (1) PT1489082E (es)
RU (1) RU2162090C2 (es)
SI (1) SI0871631T1 (es)
SK (2) SK284833B6 (es)
TW (1) TW334436B (es)
WO (1) WO1997003988A1 (es)
ZA (1) ZA965908B (es)

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PE20011289A1 (es) * 2000-04-07 2001-12-21 Upjohn Co Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles
BRPI0921546A8 (pt) 2008-11-14 2022-08-16 Merial Ltd Compostos de arilazol-2-il cianoetilamina enriquecidos enantiomericamente, método para fabricação e método de uso dos mesmos
NZ592865A (en) 2008-11-19 2013-08-30 Merial Ltd Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof
ES2537424T3 (es) 2008-12-04 2015-06-08 Merial Limited Derivados de dímeros de avermectina y de milbemicina
EP2314292A1 (en) 2009-10-20 2011-04-27 Novartis AG Endoparasiticidal compositions
AU2010325827B2 (en) 2009-12-04 2015-11-05 Basf Se Pesticidal bis-organosulfur compounds
AU2010330844B2 (en) 2009-12-17 2014-11-27 Boehringer Ingelheim Animal Health USA Inc. Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
MX336189B (es) 2009-12-17 2016-01-11 Merial Ltd Compuesto de dihidroazol antiparasiticos y composiciones qe¡ue comprenden los mismos.
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
EP2640728B1 (en) 2010-11-16 2016-09-07 Merial, Inc. Novel monensin derivatives for the treatment and prevention of protozoal infections
EP2723716B1 (en) 2011-06-27 2017-01-11 Merial, Inc. Amido-pyridyl ether compounds and compositions and their use against parasites
WO2013003168A1 (en) 2011-06-27 2013-01-03 Merial Limited Novel insect-repellent coumarin derivatives, syntheses, and methods of use
CN106474120B (zh) 2011-09-12 2020-07-28 勃林格殷格翰动物保健美国公司 包含异噁唑啉活性剂的杀寄生物组合物，其方法和用途
US20130079394A1 (en) 2011-09-23 2013-03-28 Cnrs (Centre National Recherche Scientifique) Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
CA2855954C (en) 2011-11-17 2020-09-01 Merial Limited Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof.
HUE067125T2 (hu) 2011-12-02 2024-10-28 Boehringer Ingelheim Vetmedica Gmbh Hosszú hatású injektálható moxidektin formulációk
TR201909461T4 (tr) 2012-02-06 2019-07-22 Boehringer Ingelheim Animal Health Usa Inc Si̇stemi̇k olarak etki̇ eden akti̇f maddeleri̇ i̇çeren parazi̇ti̇si̇dal oral veteri̇nerli̇ğe ai̇t bi̇leşi̇mler, bunlarin yöntemleri̇ ve kullanimlari
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
NZ701185A (en) 2012-04-20 2015-08-28 Merial Ltd Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
JP5737255B2 (ja) * 2012-09-27 2015-06-17 ダイキン工業株式会社 チオノカルボン酸エステルの製造方法
NZ716598A (en) 2012-11-20 2017-02-24 Merial Inc Anthelmintic compounds and compositions and method of using thereof
EA030935B1 (ru) 2013-11-01 2018-10-31 Мериал, Инк. Антипаразитарные и пестицидные изоксазолиновые соединения
CA2945766C (en) 2014-04-17 2023-09-26 Merial, Inc. Use of malononitrile compounds for protecting animals from parasites
CA2949511A1 (en) 2014-05-19 2015-11-26 Merial, Inc. Anthelmintic compounds
BR112016029888B1 (pt) 2014-06-19 2021-05-18 Merial, Inc composições parasiticidas compreendendo derivados de indol, métodos e usos dos mesmos
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BR112020003217A2 (pt) 2017-08-14 2020-10-06 Boehringer Ingelheim Animal Health USA Inc. compostos pesticidas e parasiticidas de pirazolisoxazolina
WO2019157241A1 (en) 2018-02-08 2019-08-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
BR112021000257A2 (pt) 2018-07-09 2021-04-06 Boehringer Ingelheim Animal Health USA Inc. Compostos heterocíclicos anti-helmínticos
US11773066B2 (en) 2018-11-20 2023-10-03 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
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Also Published As

Publication number Publication date
AR052907A1 (es) 2007-04-11
AR038429A2 (es) 2005-01-12
AR038430A2 (es) 2005-01-12
CO4750664A1 (es) 1999-03-31
CZ296008B6 (cs) 2005-12-14
FI115912B (fi) 2005-08-15
SK5498A3 (en) 1998-08-05
BR9612975B8 (pt) 2014-10-29
BR9609812B8 (pt) 2014-10-29
AU699644B2 (en) 1998-12-10
EP1489082A1 (en) 2004-12-22
HUP9802221A3 (en) 2000-05-29
ES2439569T3 (es) 2014-01-23
CA2225813C (en) 2008-02-26
AR038433A2 (es) 2005-01-12
PL185007B1 (pl) 2003-01-31
JPH11509550A (ja) 1999-08-24
EP1400523A2 (en) 2004-03-24
CN1495183A (zh) 2004-05-12
JP4122447B2 (ja) 2008-07-23
PT1489082E (pt) 2013-12-23
CN1277830C (zh) 2006-10-04
WO1997003988A1 (en) 1997-02-06
MY113806A (en) 2002-05-31
EP1400523A3 (en) 2004-04-07
JP2008007516A (ja) 2008-01-17
DE69635524D1 (de) 2006-01-05
BR9609812A (pt) 1999-03-02
BR9612944B8 (pt) 2014-10-29
BR9612972B8 (pt) 2014-10-29
NO980255D0 (no) 1998-01-20
MX9800625A (es) 1998-04-30
BR9612974B8 (pt) 2014-10-29
AR003466A1 (es) 1998-08-05
ATE311390T1 (de) 2005-12-15
HU226296B1 (hu) 2008-08-28
RU2162090C2 (ru) 2001-01-20
NO980255L (no) 1998-03-20
DE69635524T2 (de) 2006-07-06
ZA965908B (en) 1997-01-12
AU6337396A (en) 1997-02-18
NO324287B1 (no) 2007-09-17
TW334436B (en) 1998-06-21
HK1017883A1 (en) 1999-12-03
EP0871631A1 (en) 1998-10-21
AR038427A2 (es) 2005-01-12
DK0871631T3 (da) 2006-03-13
CZ11098A3 (cs) 1998-06-17
US5750695A (en) 1998-05-12
EP0871631B1 (en) 2005-11-30
FI118471B (fi) 2007-11-30
SK284833B6 (sk) 2005-12-01
FI980112L (fi) 1998-01-20
NZ311952A (en) 1999-03-29
KR100428335B1 (ko) 2004-06-16
AR038432A2 (es) 2005-01-12
CA2225813A1 (en) 1997-02-06
DK1489082T3 (da) 2013-12-09
CN1125824C (zh) 2003-10-29
HK1061242A1 (en) 2004-09-10
EP1489082B1 (en) 2013-11-20
BR9612973B8 (pt) 2014-10-29
FI20050238L (fi) 2005-03-04
SK285248B6 (sk) 2006-09-07
PL324574A1 (en) 1998-06-08
HUP9802221A2 (hu) 1999-02-01
AR038434A2 (es) 2005-01-12
AR038428A2 (es) 2005-01-12
ID30373A (id) 1997-01-23
BR9612963B8 (pt) 2014-10-29
US5703078A (en) 1997-12-30
SI0871631T1 (sl) 2006-04-30
ES2249783T3 (es) 2006-04-01
FI980112A0 (fi) 1998-01-20
CN1191537A (zh) 1998-08-26

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