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BR9612973B8 - Para-herquamidas e marcfortinas antiparasíticas. - Google Patents

Para-herquamidas e marcfortinas antiparasíticas.

Info

Publication number
BR9612973B8
BR9612973B8 BRPI9612973-5B8A BR9612973A BR9612973B8 BR 9612973 B8 BR9612973 B8 BR 9612973B8 BR 9612973 A BR9612973 A BR 9612973A BR 9612973 B8 BR9612973 B8 BR 9612973B8
Authority
BR
Brazil
Prior art keywords
marcfortines
antiparasitic
parameters
antiparasitic parameters
Prior art date
Application number
BRPI9612973-5B8A
Other languages
English (en)
Inventor
Byung H Lee
Michael F Clothier
Original Assignee
Zoetis P & U Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21695455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9612973(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zoetis P & U Llc filed Critical Zoetis P & U Llc
Publication of BR9612973B8 publication Critical patent/BR9612973B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Percussion Or Vibration Massage (AREA)
BRPI9612973-5B8A 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas. BR9612973B8 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US132495P 1995-07-21 1995-07-21

Publications (1)

Publication Number Publication Date
BR9612973B8 true BR9612973B8 (pt) 2014-10-29

Family

ID=21695455

Family Applications (7)

Application Number Title Priority Date Filing Date
BRPI9612975-1B8A BR9612975B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612974-3B8A BR9612974B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612973-5B8A BR9612973B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612944-1B8A BR9612944B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas antiparasíticas.
BRPI9612972-7B8A BR9612972B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9609812-0B8A BR9609812B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612963-8B8A BR9612963B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
BRPI9612975-1B8A BR9612975B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612974-3B8A BR9612974B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.

Family Applications After (4)

Application Number Title Priority Date Filing Date
BRPI9612944-1B8A BR9612944B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas antiparasíticas.
BRPI9612972-7B8A BR9612972B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9609812-0B8A BR9609812B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612963-8B8A BR9612963B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.

Country Status (30)

Country Link
US (2) US5703078A (pt)
EP (3) EP1400523A3 (pt)
JP (2) JP4122447B2 (pt)
KR (1) KR100428335B1 (pt)
CN (2) CN1125824C (pt)
AR (10) AR003466A1 (pt)
AT (1) ATE311390T1 (pt)
AU (1) AU699644B2 (pt)
BR (7) BR9612975B8 (pt)
CA (1) CA2225813C (pt)
CO (1) CO4750664A1 (pt)
CZ (1) CZ296008B6 (pt)
DE (1) DE69635524T2 (pt)
DK (2) DK0871631T3 (pt)
ES (2) ES2249783T3 (pt)
FI (2) FI115912B (pt)
HU (1) HU226296B1 (pt)
ID (1) ID30373A (pt)
MX (1) MX9800625A (pt)
MY (1) MY113806A (pt)
NO (1) NO324287B1 (pt)
NZ (1) NZ311952A (pt)
PL (1) PL185007B1 (pt)
PT (1) PT1489082E (pt)
RU (1) RU2162090C2 (pt)
SI (1) SI0871631T1 (pt)
SK (2) SK284833B6 (pt)
TW (1) TW334436B (pt)
WO (1) WO1997003988A1 (pt)
ZA (1) ZA965908B (pt)

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ZA976761B (en) * 1996-09-09 1999-01-29 Upjohn Co 25 Methylene and 24,25-epoxy marcfortines and paraherquamides
WO1998021211A1 (en) * 1996-11-15 1998-05-22 Pharmacia & Upjohn Company 1- and 2-substituted marcfortines and paraherquamides as antiparasitic agents
PE20011289A1 (es) * 2000-04-07 2001-12-21 Upjohn Co Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles
BRPI0921546A8 (pt) 2008-11-14 2022-08-16 Merial Ltd Compostos de arilazol-2-il cianoetilamina enriquecidos enantiomericamente, método para fabricação e método de uso dos mesmos
NZ592865A (en) 2008-11-19 2013-08-30 Merial Ltd Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof
ES2537424T3 (es) 2008-12-04 2015-06-08 Merial Limited Derivados de dímeros de avermectina y de milbemicina
EP2314292A1 (en) 2009-10-20 2011-04-27 Novartis AG Endoparasiticidal compositions
AU2010325827B2 (en) 2009-12-04 2015-11-05 Basf Se Pesticidal bis-organosulfur compounds
AU2010330844B2 (en) 2009-12-17 2014-11-27 Boehringer Ingelheim Animal Health USA Inc. Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
MX336189B (es) 2009-12-17 2016-01-11 Merial Ltd Compuesto de dihidroazol antiparasiticos y composiciones qe¡ue comprenden los mismos.
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
EP2640728B1 (en) 2010-11-16 2016-09-07 Merial, Inc. Novel monensin derivatives for the treatment and prevention of protozoal infections
EP2723716B1 (en) 2011-06-27 2017-01-11 Merial, Inc. Amido-pyridyl ether compounds and compositions and their use against parasites
WO2013003168A1 (en) 2011-06-27 2013-01-03 Merial Limited Novel insect-repellent coumarin derivatives, syntheses, and methods of use
CN106474120B (zh) 2011-09-12 2020-07-28 勃林格殷格翰动物保健美国公司 包含异噁唑啉活性剂的杀寄生物组合物,其方法和用途
US20130079394A1 (en) 2011-09-23 2013-03-28 Cnrs (Centre National Recherche Scientifique) Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
CA2855954C (en) 2011-11-17 2020-09-01 Merial Limited Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof.
HUE067125T2 (hu) 2011-12-02 2024-10-28 Boehringer Ingelheim Vetmedica Gmbh Hosszú hatású injektálható moxidektin formulációk
TR201909461T4 (tr) 2012-02-06 2019-07-22 Boehringer Ingelheim Animal Health Usa Inc Si̇stemi̇k olarak etki̇ eden akti̇f maddeleri̇ i̇çeren parazi̇ti̇si̇dal oral veteri̇nerli̇ğe ai̇t bi̇leşi̇mler, bunlarin yöntemleri̇ ve kullanimlari
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
NZ701185A (en) 2012-04-20 2015-08-28 Merial Ltd Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
JP5737255B2 (ja) * 2012-09-27 2015-06-17 ダイキン工業株式会社 チオノカルボン酸エステルの製造方法
NZ716598A (en) 2012-11-20 2017-02-24 Merial Inc Anthelmintic compounds and compositions and method of using thereof
EA030935B1 (ru) 2013-11-01 2018-10-31 Мериал, Инк. Антипаразитарные и пестицидные изоксазолиновые соединения
CA2945766C (en) 2014-04-17 2023-09-26 Merial, Inc. Use of malononitrile compounds for protecting animals from parasites
CA2949511A1 (en) 2014-05-19 2015-11-26 Merial, Inc. Anthelmintic compounds
BR112016029888B1 (pt) 2014-06-19 2021-05-18 Merial, Inc composições parasiticidas compreendendo derivados de indol, métodos e usos dos mesmos
AU2015339096B2 (en) 2014-10-31 2018-08-02 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal composition comprising fipronil
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
WO2016187534A1 (en) 2015-05-20 2016-11-24 Merial, Inc. Anthelmintic depsipeptide compounds
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
AU2017344097A1 (en) 2016-10-14 2019-05-02 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
WO2018093920A1 (en) 2016-11-16 2018-05-24 Merial, Inc. Anthelmintic depsipeptide compounds
BR112020003217A2 (pt) 2017-08-14 2020-10-06 Boehringer Ingelheim Animal Health USA Inc. compostos pesticidas e parasiticidas de pirazolisoxazolina
WO2019157241A1 (en) 2018-02-08 2019-08-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
BR112021000257A2 (pt) 2018-07-09 2021-04-06 Boehringer Ingelheim Animal Health USA Inc. Compostos heterocíclicos anti-helmínticos
US11773066B2 (en) 2018-11-20 2023-10-03 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
AU2020231319A1 (en) 2019-03-01 2021-10-21 Boehringer Ingelheim Animal Health USA Inc. Injectable clorsulon compositions, methods and uses thereof
US11560388B2 (en) 2019-03-19 2023-01-24 Boehringer Ingelheim Vetmedica Gmbh Anthelmintic aza-benzothiophene and aza-benzofuran compounds
EP4185589A1 (en) 2020-05-29 2023-05-31 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic heterocyclic compounds
CN111748503B (zh) * 2020-08-04 2021-12-14 华中农业大学 一种深海独岛枝芽胞杆菌培养基和剂型
EP4262789A1 (en) 2020-12-21 2023-10-25 Boehringer Ingelheim Vetmedica GmbH Parasiticidal collar comprising isoxazoline compounds
JP2025507585A (ja) 2022-02-17 2025-03-21 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー 流体製品メーラーを提供する方法及びシステム
WO2025257633A1 (en) 2024-06-12 2025-12-18 Boehringer Ingelheim Vetmedica Gmbh Long-acting castor oil-containing injectable formulations and methods of use thereof

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US5075307A (en) * 1987-07-28 1991-12-24 Merck & Co., Inc. Paraherquamide and dihydroparaherquamide as antihelminthic agents
US4873247A (en) * 1987-11-27 1989-10-10 Goegelman Robert T Derivatives of paraherquamide isolated from a fermentation broth active as antiparasitic agents
US4978656A (en) * 1988-08-12 1990-12-18 Merck & Co., Inc. Synthetic derivatives of paraherquamide
US4866060A (en) * 1988-08-19 1989-09-12 Merck & Co., Inc. Use of the natural product marcfortines as antiparasitic agents
US4923867A (en) * 1988-08-24 1990-05-08 Merck & Co., Inc. Synthetic marcfortine derivatives useful as antiparasitic agents
NZ233043A (en) * 1989-03-30 1992-09-25 Merck & Co Inc Anthelmintic heterocyclic compounds prepared by action of cunninghamella blakesleeana on (dihydro)paraherquamide
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TW410227B (en) * 1993-06-16 2000-11-01 Upjohn Co 14-substituted marcfortines and derivatives useful as antiparasitic agents

Also Published As

Publication number Publication date
AR052907A1 (es) 2007-04-11
AR038429A2 (es) 2005-01-12
AR038430A2 (es) 2005-01-12
CO4750664A1 (es) 1999-03-31
CZ296008B6 (cs) 2005-12-14
FI115912B (fi) 2005-08-15
SK5498A3 (en) 1998-08-05
BR9612975B8 (pt) 2014-10-29
BR9609812B8 (pt) 2014-10-29
AU699644B2 (en) 1998-12-10
EP1489082A1 (en) 2004-12-22
HUP9802221A3 (en) 2000-05-29
ES2439569T3 (es) 2014-01-23
CA2225813C (en) 2008-02-26
AR038433A2 (es) 2005-01-12
PL185007B1 (pl) 2003-01-31
JPH11509550A (ja) 1999-08-24
EP1400523A2 (en) 2004-03-24
CN1495183A (zh) 2004-05-12
JP4122447B2 (ja) 2008-07-23
PT1489082E (pt) 2013-12-23
CN1277830C (zh) 2006-10-04
WO1997003988A1 (en) 1997-02-06
MY113806A (en) 2002-05-31
EP1400523A3 (en) 2004-04-07
JP2008007516A (ja) 2008-01-17
DE69635524D1 (de) 2006-01-05
BR9609812A (pt) 1999-03-02
BR9612944B8 (pt) 2014-10-29
BR9612972B8 (pt) 2014-10-29
NO980255D0 (no) 1998-01-20
MX9800625A (es) 1998-04-30
BR9612974B8 (pt) 2014-10-29
AR038431A2 (es) 2005-01-12
AR003466A1 (es) 1998-08-05
ATE311390T1 (de) 2005-12-15
HU226296B1 (hu) 2008-08-28
RU2162090C2 (ru) 2001-01-20
NO980255L (no) 1998-03-20
DE69635524T2 (de) 2006-07-06
ZA965908B (en) 1997-01-12
AU6337396A (en) 1997-02-18
NO324287B1 (no) 2007-09-17
TW334436B (en) 1998-06-21
HK1017883A1 (en) 1999-12-03
EP0871631A1 (en) 1998-10-21
AR038427A2 (es) 2005-01-12
DK0871631T3 (da) 2006-03-13
CZ11098A3 (cs) 1998-06-17
US5750695A (en) 1998-05-12
EP0871631B1 (en) 2005-11-30
FI118471B (fi) 2007-11-30
SK284833B6 (sk) 2005-12-01
FI980112L (fi) 1998-01-20
NZ311952A (en) 1999-03-29
KR100428335B1 (ko) 2004-06-16
AR038432A2 (es) 2005-01-12
CA2225813A1 (en) 1997-02-06
DK1489082T3 (da) 2013-12-09
CN1125824C (zh) 2003-10-29
HK1061242A1 (en) 2004-09-10
EP1489082B1 (en) 2013-11-20
FI20050238L (fi) 2005-03-04
SK285248B6 (sk) 2006-09-07
PL324574A1 (en) 1998-06-08
HUP9802221A2 (hu) 1999-02-01
AR038434A2 (es) 2005-01-12
AR038428A2 (es) 2005-01-12
ID30373A (id) 1997-01-23
BR9612963B8 (pt) 2014-10-29
US5703078A (en) 1997-12-30
SI0871631T1 (sl) 2006-04-30
ES2249783T3 (es) 2006-04-01
FI980112A0 (fi) 1998-01-20
CN1191537A (zh) 1998-08-26

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Legal Events

Date Code Title Description
B22O Other matters related to patents and certificates of addition of invention: legal action concerning patent

Free format text: INPI-50400.061581/2013 ORIGEM: JUIZO DA 013A VARA FEDERAL DO RIO DE JANEIRO PROCESSO NO 0132366-77.2013.4.02.5101 ACAO DE NULIDADE DAS PATENTES SUBMETIDAS AO MAILBOX (ART. 229, PARAGRAFO UNICO DA LPI); ALTERNATIVAMENTE, A DECRETACAO DA NULIDADE PARCIAL PARA CORRECAO DO PRAZO DE VIGENCIA; SUBSIDIARIAMENTE, CASO SE ENTENDA NAO SER O CASO DE NULIDADE, A CORRECAO DO ATO ADMINISTRATIVO PARA ADEQUACAO DA VIGENCIA DAS PATENTES. AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU: PHARMACIA AND UPJOHN COMPANY, PASTEUR MERIEUX SERUMS ET VACCINS S.A.NOVEN PHARMACEUTICALS, INC.

B25D Requested change of name of applicant approved

Owner name: PHARMACIA AND UPJOHN COMPANY LLC (US)

B25A Requested transfer of rights approved

Owner name: PAH PANDU LLC (US)

B25D Requested change of name of applicant approved

Owner name: ZOETIS PANDU LLC (US)

B19A Notification of judicial decision: notification of judicial decision

Free format text: INPI-52400.61581/13 SECAO JUDICIARIA DO RIO DE JANEIRO 13A VARA FEDERAL PROCESSO NO 2014.51.01.132369-7 AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL INPI REU(S): PHARMACIA AND UP JOHN COMPANY LLC E OUTROS DECISAO: ANTECIPO OS EFEITOS DA TUTELA, A FIM DE DETERMINAR A IMEDIATA READEQUACAO DO PRAZO DE VIGENCIA DA PATENTE PI9506470-2, PI9609812-0, PI9612944-1, PI9612963-8, PI9612972-7,PI9612973-5, PI9612974-3 E PI9612975-1 PARA VINTE ANOS CONTADOS A PARTIR DO RESPECTIVO DEPOSITO, NOS TERMOS DO PARAGRAFO UNICO DO ART. 229 C/C O CAPUT DO AT. 40 DA LPI, CONFORME TABELA A SEGUIR: TITULAR: NOVEN PHARMACCEUTICALS, INC. PI9506470-2 PRAZO DE VIGENCIA: 09/01/2015. TITULAR: ZOETIS PANDU

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: REFERENTE A RPI 1932, QUANTO AO PRAZO DE VALIDADE DE ACORDO COM A DECISAO DA 13A VARA FEDERAL DO RIO DE JANEIRO

B25A Requested transfer of rights approved

Owner name: ZOETIS SERVICES LLC (US)

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 26/06/2016