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BR9612693A - Composição de estanol e uso da mesma. - Google Patents

Composição de estanol e uso da mesma.

Info

Publication number
BR9612693A
BR9612693A BR9612693-0A BR9612693A BR9612693A BR 9612693 A BR9612693 A BR 9612693A BR 9612693 A BR9612693 A BR 9612693A BR 9612693 A BR9612693 A BR 9612693A
Authority
BR
Brazil
Prior art keywords
composition
stanol
fats
edible
campestanol
Prior art date
Application number
BR9612693-0A
Other languages
English (en)
Other versions
BRPI9612693B1 (pt
BRPI9612693B8 (pt
Inventor
Ingmar Wester
Tapio Palmu
Tatu Miettinen
Helena Gylling
Original Assignee
Raision Benecol Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8546469&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9612693(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Raision Benecol Ltd filed Critical Raision Benecol Ltd
Publication of BR9612693A publication Critical patent/BR9612693A/pt
Publication of BRPI9612693B1 publication Critical patent/BRPI9612693B1/pt
Publication of BRPI9612693B8 publication Critical patent/BRPI9612693B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Edible Oils And Fats (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Seasonings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

<B>"COMPOSIçãO DE ESTANOL E USO DA MESMA"<D>. A presente invenção se refere a uma composição contendo além de sitostanol como componente principal, também uma substancial quantidade de pelo menos 10% de campestanol, tal composição sendo efetivamente encontrada como redutora dos níveis de colesterol no soro sang³íneo, quando incorporada em produtos comestíveis. Após esterificação, a composição é especialmente útil em gorduras e óleos comestíveis e em alimentos que contêm gorduras.
BRPI9612693A 1996-08-09 1996-09-02 composição de estanol e uso da mesma BRPI9612693B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI963126A FI107015B (fi) 1996-08-09 1996-08-09 Kasvistanolirasvahappoestereiden seos ja sen käyttö sekä elintarvike
PCT/FI1996/000465 WO1998006405A1 (en) 1996-08-09 1996-09-02 Stanol composition and the use thereof

Publications (3)

Publication Number Publication Date
BR9612693A true BR9612693A (pt) 1999-12-28
BRPI9612693B1 BRPI9612693B1 (pt) 2016-04-12
BRPI9612693B8 BRPI9612693B8 (pt) 2016-04-26

Family

ID=8546469

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9612693A BRPI9612693B8 (pt) 1996-08-09 1996-09-02 composição de estanol e uso da mesma

Country Status (27)

Country Link
EP (2) EP0871451B2 (pt)
JP (3) JP2000513730A (pt)
KR (1) KR100440640B1 (pt)
CN (1) CN1165312C (pt)
AT (1) ATE266408T1 (pt)
AU (1) AU734418B2 (pt)
BR (1) BRPI9612693B8 (pt)
CA (1) CA2262600C (pt)
CZ (1) CZ290903B6 (pt)
DE (1) DE69632481T3 (pt)
DK (1) DK0871451T4 (pt)
EE (1) EE03747B1 (pt)
ES (1) ES2220986T5 (pt)
FI (1) FI107015B (pt)
HU (1) HU228301B1 (pt)
IL (1) IL128458A (pt)
LT (1) LT4649B (pt)
LV (1) LV12307B (pt)
NO (1) NO326262B1 (pt)
NZ (1) NZ334496A (pt)
PL (1) PL331515A1 (pt)
PT (1) PT871451E (pt)
SI (1) SI9620141B (pt)
SK (1) SK285849B6 (pt)
UA (1) UA66763C2 (pt)
WO (1) WO1998006405A1 (pt)
ZA (1) ZA967616B (pt)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU664827B2 (en) 1991-05-03 1995-12-07 Raisio Benecol Ltd. A substance for lowering high cholesterol level in serum and a method for preparing the same
US6544973B1 (en) 1995-07-28 2003-04-08 Raisio Benecol Ltd. Substance for lowering high cholesterol level in serum and methods for preparing and using the same
US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US20030104035A1 (en) 1996-08-09 2003-06-05 Raisio Benecol Ltd. Stanol composition and the use thereof
UA69378C2 (uk) * 1996-11-04 2004-09-15 Райзіо Бенекол Лтд. Текстуруюча композиція, текстуруючий агент, харчовий продукт, жирові суміші та способи їх одержання
US6929816B2 (en) 1998-01-21 2005-08-16 Raisio Benecol Ltd. Fat compositions for use in food
FI107538B (fi) 1997-02-26 2001-08-31 Raisio Benecol Oy Menetelmä stanoliesterien valmistamiseksi
ES2222553T3 (es) * 1997-08-22 2005-02-01 Unilever N.V. Producto alimenticio a base de grasa que comprende esteroles.
EP1440619B1 (en) * 1997-08-22 2006-11-02 Unilever N.V. Fat based food products comprising sterols
DE69818942T2 (de) 1997-08-22 2004-09-09 Unilever N.V. Stanolester enthaltende Zusammensetzungen
ES2231940T3 (es) * 1997-08-22 2005-05-16 Unilever N.V. Composicion de esteres de estanol.
EP0897971B1 (en) * 1997-08-22 2004-11-03 Unilever N.V. Stanol ester composition
DK0897970T3 (da) * 1997-08-22 2004-11-08 Unilever Nv Fremgangsmåde til fremstilling af stanolestere
FI974648A7 (fi) 1997-09-09 1999-05-06 Raisio Benecol Oy Hydroksihappo-, maitohappo- ja hydroksialkanoaattiesterit ja niiden käyttö
WO1999048907A1 (de) * 1998-03-23 1999-09-30 Cognis Deutschland Gmbh Verfahren zur herstellung von stanolen
US6025348A (en) * 1998-04-30 2000-02-15 Kao Corporation Oil and fat composition containing phytosterol
US6123978A (en) * 1998-08-31 2000-09-26 Mcneil-Ppc, Inc. Stable salad dressings
US6277431B1 (en) * 1998-10-14 2001-08-21 Redeem, Inc. Anticholesterolemic edible oil
FI115527B (fi) * 1998-10-16 2005-05-31 Upm Kymmene Oyj Kasvisterolijohdannaisten käyttö ja niitä sisältäviä tuotteita
NZ501169A (en) * 1998-11-26 2001-05-25 F Fatty acid esters of phytosterol and phytostanol
US6113972A (en) * 1998-12-03 2000-09-05 Monsanto Co. Phytosterol protein complex
DE69908643T2 (de) 1998-12-23 2004-05-13 G.D. Searle Llc, Chicago Kombinationen von cholesteryl ester transfer protein inhibitoren und nicotinsäure derivaten für kardiovaskuläre indikationen
WO2000047701A2 (en) 1999-02-10 2000-08-17 Eastman Chemical Company Corn fiber for the production of advanced chemicals and materials
EP1169462B1 (en) 1999-04-12 2009-10-21 Monsanto Technology LLC Oil comprising brassicastanol
FI991533L (fi) * 1999-07-05 2001-01-06 Sohkar Oy Menetelmä orgaanisten aineiden käsittelemiseksi
US6998501B1 (en) 1999-08-30 2006-02-14 Ocean Nutrition Canada Limited Nutritional supplement for lowering serum triglyceride and cholesterol levels
US7157619B1 (en) 1999-08-30 2007-01-02 Monsanto Technology, L.L.C. Plant sterol acyltransferases
WO2001015552A1 (en) * 1999-08-30 2001-03-08 Ocean Nutrition Canada Ltd. A nutritional supplement for lowering serum triglyceride and cholesterol levels
US6677327B1 (en) 1999-11-24 2004-01-13 Archer-Daniels-Midland Company Phytosterol and phytostanol compositions
ATE323714T1 (de) * 2000-01-21 2006-05-15 Forbes Medi Tech Inc Krystalline zusammensetzungen enthaltend phytosterole und phytostanole oder derivate davon
CA2395447A1 (en) 2000-01-28 2001-08-02 Robert Joseph Sarama Palatable arginine compounds and uses thereof for cardiovascular health
ES2298197T3 (es) * 2000-01-31 2008-05-16 Harting S.A. Composiciones que contienen esteres de acidos grasos de fitosterol y de policosanol para reducir el colesterol y los trigliceridos de la sangre.
AU2001253294A1 (en) 2000-04-14 2001-10-30 Mars, Incorporated Compositions and methods for improving vascular health
FI20010780A0 (fi) * 2001-04-12 2001-04-12 Raisio Benecol Oy Parannetut koostumukset
JP2005521653A (ja) 2002-01-17 2005-07-21 ファルマシア コーポレイション 先端ナトリウム同時依存性胆汁酸輸送（ａｓｂｔ）およびタウロコール酸塩取込みの阻害剤としての新規アルキル／アリールヒドロキシまたはケトチエピン化合物
US20080182801A1 (en) 2003-12-22 2008-07-31 Btg International Limited Core 2 glcnac-t inhibitors
GB0513881D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors III
GB0329667D0 (en) 2003-12-22 2004-01-28 King S College London Core 2 GlcNAc-T inhibitor
US8158184B2 (en) 2004-03-08 2012-04-17 Bunge Oils, Inc. Structured lipid containing compositions and methods with health and nutrition promoting characteristics
GB0513883D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Diagnosis of Atherosclerosis
GB0513888D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors II
IE20060710A1 (en) * 2005-09-28 2007-07-25 Alltracel Dev Services Ltd Use of polyanhydroglucronic acid
CA2673005A1 (en) * 2005-12-20 2007-06-28 Forbes Medi-Tech Inc. Emulsions comprising non-esterified phytosterols in the aqueous phase
US20070148311A1 (en) 2005-12-22 2007-06-28 Bunge Oils, Inc. Phytosterol esterification product and method of make same
DE102006041302A1 (de) * 2006-03-08 2007-09-13 Cognis Ip Management Gmbh Sterolester mit kurzkettigen Fettsäuren
AU2007222697B2 (en) * 2006-03-08 2012-07-05 Cognis Ip Management Gmbh Powder containing sterol
US20080124387A1 (en) 2006-11-27 2008-05-29 Kapac, Llc Methods and formulations for enhancing the absorption and decreasing the absorption variability of orally administered drugs, vitamins and nutrients
FI123374B (fi) 2011-03-25 2013-03-15 Ravintoraisio Oy Uusi syötävä koostumus
PL3287014T3 (pl) * 2016-08-22 2020-08-24 Verbio Vereinigte Bioenergie Ag Sposób wytwarzania kompozycji fitosteroli-fitostanoli
WO2021170873A1 (en) * 2020-02-27 2021-09-02 Basf Se Composition for the treatment of (pre)hypercholesterolemia and/or associated morbidities thereto
GB202110358D0 (en) * 2021-07-19 2021-09-01 Meda Pharma S P A Composition

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU664827B2 (en) * 1991-05-03 1995-12-07 Raisio Benecol Ltd. A substance for lowering high cholesterol level in serum and a method for preparing the same
US5244887A (en) * 1992-02-14 1993-09-14 Straub Carl D Stanols to reduce cholesterol absorption from foods and methods of preparation and use thereof

Also Published As

Publication number Publication date
HUP0001020A3 (en) 2001-10-29
CN1165312C (zh) 2004-09-08
JP2009102421A (ja) 2009-05-14
LV12307A (lv) 1999-07-20
FI963126A0 (fi) 1996-08-09
CZ290903B6 (cs) 2002-11-13
FI107015B (fi) 2001-05-31
BRPI9612693B1 (pt) 2016-04-12
EP1452180A1 (en) 2004-09-01
CZ34699A3 (cs) 1999-07-14
JP2000513730A (ja) 2000-10-17
CA2262600A1 (en) 1998-02-19
JP4554915B2 (ja) 2010-09-29
EE9900040A (et) 1999-08-16
BRPI9612693B8 (pt) 2016-04-26
DE69632481T2 (de) 2005-05-12
UA66763C2 (en) 2004-06-15
HUP0001020A2 (hu) 2000-08-28
SI9620141A (sl) 1999-10-31
HU228301B1 (en) 2013-03-28
ES2220986T3 (es) 2004-12-16
ZA967616B (en) 1997-04-16
IL128458A (en) 2004-07-25
ES2220986T5 (es) 2008-11-01
DK0871451T3 (da) 2004-09-20
FI963126L (fi) 1998-02-10
LT4649B (lt) 2000-04-25
KR20000029884A (ko) 2000-05-25
EP0871451B2 (en) 2008-07-09
WO1998006405A1 (en) 1998-02-19
CN1228025A (zh) 1999-09-08
SI9620141B (sl) 2008-10-31
SK285849B6 (sk) 2007-09-06
LV12307B (en) 1999-10-20
DE69632481T3 (de) 2008-11-27
LT99018A (lt) 1999-12-27
AU6823096A (en) 1998-03-06
IL128458A0 (en) 2000-01-31
SK11299A3 (en) 1999-09-10
ATE266408T1 (de) 2004-05-15
PL331515A1 (en) 1999-07-19
EP0871451B1 (en) 2004-05-12
JP2004143181A (ja) 2004-05-20
PT871451E (pt) 2004-09-30
DK0871451T4 (da) 2008-11-10
NO990559D0 (no) 1999-02-05
KR100440640B1 (ko) 2004-07-19
AU734418B2 (en) 2001-06-14
NZ334496A (en) 2000-07-28
CA2262600C (en) 2009-11-17
NO990559L (no) 1999-02-05
DE69632481D1 (de) 2004-06-17
NO326262B1 (no) 2008-10-27
EP0871451A1 (en) 1998-10-21
EE03747B1 (et) 2002-06-17

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B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

Free format text: EM VIRTUDE DO ACRESCIMO DE 5 (CINCO) REIVINDICACOES NO NOVO QUADRO REIVINDICATORIO SUBMETIDO ATRAVES DA PETICAO NO 061604 DE 12 DE NOVEMBRO DE 2002, SEM QUE TENHA SIDO FEITA A DEVIDA RETRIBUICAO, A REQUERENTE DEVE COMPLEMENTAR O PAGAMENTO REFERENTE A ESTAS REIVINDICACOES ADICIONAIS. ADICIONALMENTE, A REQUERENTE TAMBEM DEVE FAZER A CPMPLEMENTACAO DE RETRIBUICAO REFERENTE AO DESPACHO 7.1 (CIENCIA DE PARECER), CUJA NOTIFICACAO FOI PUBLICADA NA RPI NO 1650 DE 20/08/2002, TENDO EM VISTA QUE O VALOR PAGO PELA REQUERENTE FOI REFERENTE A CUMPRIMENTO DE EXIGENCIA. PEDE-SE, PORTANTO, QUE SEJAM SANADAS TAIS IRREGULARIDADES PARA QUE SE DE PROSSEGUIMENTO AO EXAME TECNICO.

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