BR9612422A - Pseudo-partìculas virais recombinantes, composição, utilização de pseudo-partìculas, e, processo de estimulação in vitro de respostas t citotóxicas de linfócitos provenientes de indivìduos atingidos por infecções virais ou tumorais. - Google Patents
Pseudo-partìculas virais recombinantes, composição, utilização de pseudo-partìculas, e, processo de estimulação in vitro de respostas t citotóxicas de linfócitos provenientes de indivìduos atingidos por infecções virais ou tumorais.Info
- Publication number
- BR9612422A BR9612422A BR9612422-9A BR9612422A BR9612422A BR 9612422 A BR9612422 A BR 9612422A BR 9612422 A BR9612422 A BR 9612422A BR 9612422 A BR9612422 A BR 9612422A
- Authority
- BR
- Brazil
- Prior art keywords
- pseudo
- particles
- viral
- lymphocytes
- cytotoxic
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 4
- 230000003612 virological effect Effects 0.000 title abstract 4
- 231100000433 cytotoxic Toxicity 0.000 title abstract 2
- 230000001472 cytotoxic effect Effects 0.000 title abstract 2
- 238000000338 in vitro Methods 0.000 title abstract 2
- 210000004698 lymphocyte Anatomy 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000000638 stimulation Effects 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108700018351 Major Histocompatibility Complex Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000527 lymphocytic effect Effects 0.000 abstract 1
- 238000001338 self-assembly Methods 0.000 abstract 1
- 210000000605 viral structure Anatomy 0.000 abstract 1
- 229960004854 viral vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14311—Parvovirus, e.g. minute virus of mice
- C12N2750/14322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
- Y10S977/802—Virus-based particle
- Y10S977/803—Containing biological material in its interior
- Y10S977/804—Containing nucleic acid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
''PSEUDO-PARTìCULAS VIRAIS RECOMBINANTES, COMPOSIçãO, UTILIZAçãO DE PSEUDO-PARTìCULAS, E, PROCESSO DE ESTIMULAçãO IN VITRO DE RESPOSTAS T CITOTóXICAS DE LINFóCITOS PROVENIENTES DE INDIVìDUOS ATINGIDOS POR INFECçõES VIRAIS OU TUMORAIS''. Pseudo-partículas virais recombinantes caracterizadas em que elas são constituídas por auto-montagem de pelo menos uma proteína de estrutura viral, em que elas tem um tamanho compreendido entre cerca de 20 e 60 nm, e em que elas formam uma estrutura aproximadamente isoesaédrica, e em que a referida proteína é mdificada pela presença de pelo menos um epítopo compreendendo uma seq³ência de 8 a 25 aminoácidos suscetível de se associar com pelo menos uma molécula de classe I e/ou II do complexo principal de histocompatibilidade, com exclusão do epítopo C3:T, a referida associação sendo reconhecida pelos linfócitos TCD8^ +^ citotóxicos e/ou TCD4^ +^. Estas pseudo-partículas podem ser usadas como vacinas antivirais ou como medicamentos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96400009A EP0783038B1 (fr) | 1996-01-02 | 1996-01-02 | Pseudo-particules virales recombinantes et applications vaccinales et antitumorales |
| PCT/FR1996/001337 WO1997024443A1 (fr) | 1996-01-02 | 1996-08-30 | Pseudo-particules virales recombinantes et applications vaccinales et antitumorales |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9612422A true BR9612422A (pt) | 1999-12-28 |
Family
ID=8225214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9612422-9A BR9612422A (pt) | 1996-01-02 | 1996-08-30 | Pseudo-partìculas virais recombinantes, composição, utilização de pseudo-partìculas, e, processo de estimulação in vitro de respostas t citotóxicas de linfócitos provenientes de indivìduos atingidos por infecções virais ou tumorais. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6458362B1 (pt) |
| EP (2) | EP0783038B1 (pt) |
| JP (1) | JP2000502900A (pt) |
| AT (1) | ATE317901T1 (pt) |
| AU (1) | AU731706B2 (pt) |
| BR (1) | BR9612422A (pt) |
| CA (1) | CA2241280A1 (pt) |
| DE (1) | DE69635825T2 (pt) |
| DK (1) | DK0871738T3 (pt) |
| ES (2) | ES2282998T3 (pt) |
| IL (1) | IL167886A (pt) |
| NO (1) | NO324205B1 (pt) |
| NZ (1) | NZ316970A (pt) |
| PT (1) | PT871738E (pt) |
| WO (1) | WO1997024443A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60124523T2 (de) * | 2001-07-10 | 2007-09-06 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Zusammensetzung einer Parvovirus VP1-Proteinvariante und eines arvovirus NS1-Proteins zur Induktion von Zytolyse |
| EP1614096A1 (en) * | 2003-04-07 | 2006-01-11 | Koninklijke Philips Electronics N.V. | Display device |
| ES2307345B1 (es) * | 2004-01-21 | 2009-11-13 | Consejo Sup. Investig. Cientificas | Capsidas vacias quimericas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones. |
| ES2307346B1 (es) * | 2004-01-21 | 2009-11-13 | Consejo Sup. Investig. Cientificas | Capsidas vacias (vlps(-vp4)) del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones. |
| ES2310062B1 (es) | 2005-07-15 | 2009-11-13 | Bionostra, S.L. | Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones. |
| US20090092638A1 (en) * | 2007-09-14 | 2009-04-09 | Institut Pasteur And Inserm | Polynucleotides allowing the expression and secretion of recombinant pseudo-virus containing foreign epitopes, their production, and use |
| EP2268801A4 (en) * | 2008-03-14 | 2011-12-28 | Us Gov Health & Human Serv | COMPOSITIONS AND METHODS RELATED TO A HUMAN BOCAVIRUS |
| CN116640189B (zh) * | 2023-04-13 | 2024-08-27 | 北京烁谷生物科技有限公司 | 一种病原微生物快速检测试剂盒及其应用 |
| CN117866053B (zh) * | 2024-01-10 | 2024-07-02 | 武汉珈创生物技术股份有限公司 | 同时检测多种猪细小病毒的多克隆抗体及其制备和应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8902301A (nl) * | 1989-09-14 | 1991-04-02 | Rijksuniversiteit | Humaan parvovirus b19 eiwitten, hun produktie en hun gebruik in diagnostische assays en vaccins. |
-
1996
- 1996-01-02 ES ES96400009T patent/ES2282998T3/es not_active Expired - Lifetime
- 1996-01-02 EP EP96400009A patent/EP0783038B1/fr not_active Expired - Lifetime
- 1996-08-30 NZ NZ316970A patent/NZ316970A/xx not_active IP Right Cessation
- 1996-08-30 JP JP09524051A patent/JP2000502900A/ja active Pending
- 1996-08-30 DK DK96930192T patent/DK0871738T3/da active
- 1996-08-30 EP EP96930192A patent/EP0871738B1/fr not_active Expired - Lifetime
- 1996-08-30 CA CA002241280A patent/CA2241280A1/fr not_active Abandoned
- 1996-08-30 DE DE69635825T patent/DE69635825T2/de not_active Expired - Lifetime
- 1996-08-30 AU AU69332/96A patent/AU731706B2/en not_active Ceased
- 1996-08-30 AT AT96930192T patent/ATE317901T1/de active
- 1996-08-30 BR BR9612422-9A patent/BR9612422A/pt not_active Application Discontinuation
- 1996-08-30 US US08/704,867 patent/US6458362B1/en not_active Expired - Fee Related
- 1996-08-30 WO PCT/FR1996/001337 patent/WO1997024443A1/fr not_active Ceased
- 1996-08-30 PT PT96930192T patent/PT871738E/pt unknown
- 1996-08-30 ES ES96930192T patent/ES2257753T3/es not_active Expired - Lifetime
-
1998
- 1998-06-30 IL IL167886A patent/IL167886A/en not_active IP Right Cessation
- 1998-07-01 NO NO19983054A patent/NO324205B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997024443A1 (fr) | 1997-07-10 |
| IL167886A (en) | 2011-02-28 |
| DE69635825T2 (de) | 2006-10-19 |
| NO983054D0 (no) | 1998-07-01 |
| NZ316970A (en) | 1999-03-29 |
| EP0783038A1 (fr) | 1997-07-09 |
| JP2000502900A (ja) | 2000-03-14 |
| ES2282998T3 (es) | 2007-10-16 |
| ATE317901T1 (de) | 2006-03-15 |
| NO324205B1 (no) | 2007-09-10 |
| AU731706B2 (en) | 2001-04-05 |
| AU6933296A (en) | 1997-07-28 |
| DE69635825D1 (de) | 2006-04-20 |
| ES2257753T3 (es) | 2006-08-01 |
| PT871738E (pt) | 2006-07-31 |
| CA2241280A1 (fr) | 1997-07-10 |
| DK0871738T3 (da) | 2006-06-19 |
| EP0871738B1 (fr) | 2006-02-15 |
| EP0783038B1 (fr) | 2007-04-04 |
| US6458362B1 (en) | 2002-10-01 |
| NO983054L (no) | 1998-08-14 |
| EP0871738A1 (fr) | 1998-10-21 |
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| FA10 | Dismissal: dismissal - article 33 of industrial property law |