[go: up one dir, main page]

BR9609399A - Elementos de proteìnas de choque térmico estreptocócicos da famìlia hsp70 - Google Patents

Elementos de proteìnas de choque térmico estreptocócicos da famìlia hsp70

Info

Publication number
BR9609399A
BR9609399A BR9609399-4A BR9609399A BR9609399A BR 9609399 A BR9609399 A BR 9609399A BR 9609399 A BR9609399 A BR 9609399A BR 9609399 A BR9609399 A BR 9609399A
Authority
BR
Brazil
Prior art keywords
seq
heat shock
shock proteins
hsp70
hsps
Prior art date
Application number
BR9609399-4A
Other languages
English (en)
Inventor
Josee Hamel
Bernard R Brodeur
Denis Martin
Clement Rioux
Original Assignee
Biochem Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/472,534 external-priority patent/US5919620A/en
Application filed by Biochem Vaccines Inc filed Critical Biochem Vaccines Inc
Publication of BR9609399A publication Critical patent/BR9609399A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1275—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

ELEMENTOS DE PROTEìNAS DE CHOQUE TéRMICO ESTREPTOCóCICOS DA FAMìLIA HSP70. São descritas novas proteínas de choque térmico (HSPs) de Streptococcus pneumoniae, Sterptococcus pyogenes e Streptococcus agalactiae tendo massas moleculares aparentes de 70 a 72 KDa, polipeptídeos imunologicamente relacionados, o nucleotídeo e seq³ências de aminoácido derivadas de HSP72 de S. pneumoniae (SEQ ID NO: 4; SEQ ID NO: 5), o nucleotídeo e sequências de aminoácido derivadas de HSP70 de S. pyogenes (SEQ ID NO: 19; SEQ ID NO:20), o nucleotídeo e as sequências de aminoácido derivadas de HSP70 de S. agalactiae (SEQ ID NO:21; SEQ ID NO:22), anticorpos se ligam às HSPs e métodos de DNA recombinante para a produção das HSPs e polipeptídeos imunologicamente relacionados. Os polipeptídeos, as seq³ências de DNA e os anticorpos desta invenção proporcionam novos meios de diagnóstico, prevenção e/ou tratamento de doença estreptocócica.
BR9609399-4A 1995-06-07 1996-05-17 Elementos de proteìnas de choque térmico estreptocócicos da famìlia hsp70 BR9609399A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/472,534 US5919620A (en) 1995-06-07 1995-06-07 Heat shock protein HSP72 of Streptococcus pneumoniae
US180595P 1995-08-04 1995-08-04
PCT/CA1996/000322 WO1996040928A1 (en) 1995-06-07 1996-05-17 Streptococcal heat shock proteins members of the hsp70 family

Publications (1)

Publication Number Publication Date
BR9609399A true BR9609399A (pt) 2001-08-28

Family

ID=26669494

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9609399-4A BR9609399A (pt) 1995-06-07 1996-05-17 Elementos de proteìnas de choque térmico estreptocócicos da famìlia hsp70

Country Status (18)

Country Link
EP (1) EP0832238A1 (pt)
JP (1) JPH11507214A (pt)
KR (1) KR19990022742A (pt)
CN (1) CN1192241A (pt)
AP (1) AP9701163A0 (pt)
AR (1) AR003124A1 (pt)
AU (1) AU700080B2 (pt)
BR (1) BR9609399A (pt)
CA (1) CA2224015A1 (pt)
CZ (1) CZ394297A3 (pt)
EA (1) EA199800046A1 (pt)
HU (1) HUP0600442A3 (pt)
IL (1) IL118329A0 (pt)
NO (1) NO975752L (pt)
PL (1) PL323781A1 (pt)
SK (1) SK168497A3 (pt)
TR (1) TR199701537T1 (pt)
WO (1) WO1996040928A1 (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2253252A1 (en) * 1996-05-01 1997-11-06 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
US6245335B1 (en) 1996-05-01 2001-06-12 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
JP2002508156A (ja) * 1997-12-31 2002-03-19 ストレスジェン バイオテクノロジーズ コーポレイション Ｈｓｐ６０ファミリーのＳｔｒｅｐｔｏｃｏｃｃｕｓ熱ショックタンパク質
US6497880B1 (en) 1998-12-08 2002-12-24 Stressgen Biotechnologies Corporation Heat shock genes and proteins from Neisseria meningitidis, Candida glabrata and Aspergillus fumigatus
KR100802198B1 (ko) * 1998-12-23 2008-02-11 샤이어 바이오켐 인코포레이티드 신규한 스트렙토코커스 항원
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
HU229968B1 (hu) 1999-03-19 2015-03-30 Smithkline Beecham Biologicals S.A Sztreptokokkusz oltóanyag
US7015309B1 (en) 1999-06-23 2006-03-21 The Wistar Institute Of Anatomy And Biology Pyrrhocoricin-derived peptides, and methods of use thereof
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
AU2005204321B2 (en) * 1999-08-19 2008-07-10 Immunobiology Limited Vaccines from Infectious Agents
GB9919734D0 (en) * 1999-08-19 1999-10-20 Colaco Camilo Vaccines from infectious agents
EP1252517A4 (en) * 2000-01-21 2004-10-20 Wistar Inst BIOCID MOLECULES, MACROMOLECULAR OBJECTIVES AND METHOD FOR THE PRODUCTION AND USE
US6833134B2 (en) 2000-06-12 2004-12-21 University Of Saskacthewan Immunization of dairy cattle with GapC protein against Streptococcus infection
EP1294771B1 (en) 2000-06-12 2008-10-29 University Of Saskatchewan Chimeric GapC protein from Streptococcus and its use in vaccination and diagnosis
US6866855B2 (en) 2000-06-12 2005-03-15 University Of Saskatchewan Immunization of dairy cattle with GapC protein against Streptococcus infection
GB0021757D0 (en) * 2000-09-04 2000-10-18 Colaco Camilo Vaccine against microbial pathogens
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
JP4740738B2 (ja) 2002-08-02 2011-08-03 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
JP4579156B2 (ja) 2002-11-01 2010-11-10 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 免疫原組成物
EP2287311A1 (en) * 2003-03-04 2011-02-23 Intercell AG Streptococcus pyogenes antigens
EP2336357A1 (en) * 2003-04-15 2011-06-22 Intercell AG S. pneumoniae antigens
WO2005032584A2 (en) 2003-10-02 2005-04-14 Glaxosmithkline Biologicals S.A. Pertussis antigens and use thereof in vaccination
GB0505996D0 (en) 2005-03-23 2005-04-27 Glaxosmithkline Biolog Sa Fermentation process
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
CN104436180B (zh) 2006-01-17 2021-08-31 阿恩·福斯格伦 新的表面外露流感嗜血菌蛋白质(蛋白质E；pE)
CN102869377A (zh) 2010-03-10 2013-01-09 葛兰素史密丝克莱恩生物有限公司 免疫原性组合物
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
CN103146734B (zh) * 2013-03-12 2014-10-01 中国人民解放军军事医学科学院军事兽医研究所 抗烧烫伤感染多器官衰竭绿脓杆菌毒素疫苗
CN104001164A (zh) * 2014-04-23 2014-08-27 杭州师范大学 一种嗜水气单胞菌热激蛋白亚单位疫苗及其制备方法
CN114805567B (zh) * 2022-06-27 2022-09-16 和元生物技术（上海）股份有限公司 识别外泌体的标志蛋白hspa1a的单克隆抗体、方法和应用
CN116258247A (zh) * 2022-12-26 2023-06-13 三峡大学 一种基于SAINet神经网络模型的电力负荷预测方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0571538B1 (en) * 1991-02-15 1998-07-08 The Uab Research Foundation Structural gene of pneumococcal protein
IT1262896B (it) * 1992-03-06 1996-07-22 Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.

Also Published As

Publication number Publication date
TR199701537T1 (xx) 1998-03-21
EA199800046A1 (ru) 1998-06-25
EP0832238A1 (en) 1998-04-01
AU700080B2 (en) 1998-12-17
PL323781A1 (en) 1998-04-27
KR19990022742A (ko) 1999-03-25
WO1996040928A1 (en) 1996-12-19
AP9701163A0 (en) 1998-01-31
JPH11507214A (ja) 1999-06-29
CA2224015A1 (en) 1996-12-19
HUP0600442A3 (en) 2007-03-28
SK168497A3 (en) 1998-07-08
CZ394297A3 (cs) 1998-04-15
AU5682896A (en) 1996-12-30
CN1192241A (zh) 1998-09-02
NO975752D0 (no) 1997-12-05
IL118329A0 (en) 1996-09-12
HUP0600442A2 (en) 2006-08-28
NO975752L (no) 1998-02-06
AR003124A1 (es) 1998-07-08

Similar Documents

Publication Publication Date Title
BR9609399A (pt) Elementos de proteìnas de choque térmico estreptocócicos da famìlia hsp70
Porter Chemical structure of γ-globulin and antibodies
ATE382055T1 (de) Wnt-1 verwandte polypeptide und dafür kodierende nukleinsäuren
FR2637612B1 (fr) Sequences de nucleotides codant pour une proteine a activite ureasique
ATE184052T1 (de) Gdf-1 und uog1 proteine
HUP9702387A1 (hu) Neisseria meningitidis proteináz-K-rezisztens felszíni fehérjéje
GR900100716A (el) C3B/C4B υποδοχέας (CR1).
PT93910A (pt) Prodesso para a preparacao de uma proteina heterologa mediante secrecao a partir de uma celula
ATE380867T1 (de) Lactoferrinrezeptorgen von moraxella
Gallizia et al. Production of a soluble and functional recombinant streptavidin inescherichia coli
WO2001005422A3 (fr) Utilisation d'un polypeptique pour detecter, prevenir ou traiter un etat pathologique associe a une maladie degenerative, neurologique autoimmune
DE69533255D1 (de) ISOLIERTES p27 PROTEIN UND NUKLEINSÄURE DAFÜR KODIEREND
DE69637148D1 (de) Nukleinsäuremoleküle, proteine und peptide, die im zusammenhang stehen mit dickdarmzellen und dickdarm-krebszellen
KR930700661A (ko) 다양한 cd44 표면단백질, 이단백질을 코딩하는 dna 서열, 이단백질에 대한 항체와 진단과 치료의 용도
US7022485B1 (en) Fibrin citrulline derivatives and their use for diagnosing or treating rheumatoid arthritis
JP2829405B2 (ja) 機能性ポリペプチド
Benyamin et al. Anti-actin antibodies Chemical modification allows the selective production of antibodies to the N-terminal region
IE910820A1 (en) Gp75 as a tumor vaccine for melanoma
BR0012038A (pt) Molécula de ácido nucleico isolada, vetor, célula hospedeira, polopeptìdeo, proteìna, e, métodos para produzir um polipeptìdeo, para produzir um produto quìmico fino, e, de diagnosticar a presença ou atividade de corybacterium diphotheriae em um paciente
WO2000020447A3 (en) Polynucleotides coding for secreted polypeptides, some having similarity to syncollin or claudin or cytokine, their therapeutic uses
KR940021579A (ko) 골(骨)-관련 전사 조절인자형 단백질 및 이의 제조방법
WO1992007939A3 (en) Polypeptide with 46kd hmfg differentiation antigen binding specificity
EP0504335A1 (en) A fibronectin binding peptide
WO1995008628A3 (en) Nucleic acids encoding merosin, merosin fragments and uses thereof
Givol et al. Isolation and fragmentation of antibodies to polytyrosyl gelatin

Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law