[go: up one dir, main page]

BR9504072A - Composiçao farmacêutica métodos para o tratamento de hipercolesterolemia de aterosclerose e kit - Google Patents

Composiçao farmacêutica métodos para o tratamento de hipercolesterolemia de aterosclerose e kit

Info

Publication number
BR9504072A
BR9504072A BR9504072A BR9504072A BR9504072A BR 9504072 A BR9504072 A BR 9504072A BR 9504072 A BR9504072 A BR 9504072A BR 9504072 A BR9504072 A BR 9504072A BR 9504072 A BR9504072 A BR 9504072A
Authority
BR
Brazil
Prior art keywords
hypercholesterolemia
atherosclerosis
kit
treatment
pharmaceutical composition
Prior art date
Application number
BR9504072A
Other languages
English (en)
Inventor
Lee A Morehouse
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR9504072A publication Critical patent/BR9504072A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BR9504072A 1994-09-20 1995-09-19 Composiçao farmacêutica métodos para o tratamento de hipercolesterolemia de aterosclerose e kit BR9504072A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30890894A 1994-09-20 1994-09-20

Publications (1)

Publication Number Publication Date
BR9504072A true BR9504072A (pt) 1996-07-30

Family

ID=23195885

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9504072A BR9504072A (pt) 1994-09-20 1995-09-19 Composiçao farmacêutica métodos para o tratamento de hipercolesterolemia de aterosclerose e kit

Country Status (12)

Country Link
US (1) US5807834A (pt)
EP (1) EP0782451A1 (pt)
JP (1) JPH09511753A (pt)
AU (1) AU2453295A (pt)
BR (1) BR9504072A (pt)
CA (1) CA2200436A1 (pt)
FI (1) FI971151A0 (pt)
HR (1) HRP950488A2 (pt)
IL (1) IL115310A0 (pt)
MX (1) MX9702175A (pt)
WO (1) WO1996009827A2 (pt)
ZA (1) ZA957879B (pt)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995018143A1 (en) * 1993-12-28 1995-07-06 Pfizer Inc. Hypocholesterolemic agents
WO1996020184A1 (en) * 1994-12-23 1996-07-04 Pfizer Inc. Naphthyl-benzoxazepines or -benzothiazepines as squalene synthetase inhibitors
US5965553A (en) * 1996-06-20 1999-10-12 Pfizer Inc. Squalene synthetase inhibitors
US6537987B1 (en) * 1996-06-20 2003-03-25 Pfizer Inc. 4,1-benzoxazepines or 4,1-benzothiazepines and their use as squalene synthetase inhibitors
US6352982B1 (en) 1997-04-21 2002-03-05 Takeda Chemical Industries, Ltd. 4,1-benzoxazepines, their analogues, and their use as somatostatin agonists
US6180660B1 (en) * 1997-08-26 2001-01-30 Merck & Co., Inc. Cholesterol-lowering therapy
US20030153541A1 (en) * 1997-10-31 2003-08-14 Robert Dudley Novel anticholesterol compositions and method for using same
GB9923076D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
DE69933016T2 (de) * 1998-03-26 2007-03-29 Phytopharm Plc, Godmanchester Steroidale saponine zur behandlung der alzheimerischen krankheit
US6207664B1 (en) 1998-11-25 2001-03-27 Pfizer Inc. Squalene synthetase inhibitor agents
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
US6465011B2 (en) 1999-05-29 2002-10-15 Abbott Laboratories Formulations comprising lipid-regulating agents
US6372251B2 (en) 1999-06-11 2002-04-16 Abbott Laboratories Formulations comprising lipid-regulating agents
GB9923077D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
US20030092745A1 (en) * 2000-02-25 2003-05-15 Pfizer Inc. Combination therapy
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
ATE331512T1 (de) 2001-01-26 2006-07-15 Schering Corp Verwendung azetidinone-substituierter verbindungen zur behandlung der sitosterolhämie
MEP27808A (en) 2001-01-26 2010-10-10 Schering Corp Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
GB0107822D0 (en) * 2001-03-28 2001-05-23 Phytopharm Plc Sapogenin derivatives their synthesis and use methods based upon their use
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
JP2005504091A (ja) 2001-09-21 2005-02-10 シェーリング　コーポレイション ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
US20050130948A1 (en) * 2002-03-27 2005-06-16 Daryl Rees Therapeutic methods and uses of sapogenins and their derivatives
KR101130212B1 (ko) * 2002-03-27 2012-04-13 파이토팜 피엘씨 사포게닌 및 그 유도체의 치료 방법 및 사용법
GB0215579D0 (en) 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds
AR040588A1 (es) 2002-07-26 2005-04-13 Schering Corp Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
DE60331572D1 (de) * 2002-10-28 2010-04-15 Phytopharm Plc Godmanchester Stereospezifische reduktion von sapogen-3-onen
WO2004043457A1 (en) 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
EP1606287B1 (en) 2003-03-07 2013-10-02 Merck Sharp & Dohme Corp. Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
MXPA05009501A (es) 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
CA2517571C (en) 2003-03-07 2011-07-05 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP2007512359A (ja) 2003-11-19 2007-05-17 メタバシス・セラピューティクス・インコーポレイテッド 新規なリン含有甲状腺ホルモン様物質
US7871998B2 (en) 2003-12-23 2011-01-18 Astrazeneca Ab Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity
JP4477474B2 (ja) * 2004-11-15 2010-06-09 株式会社日立製作所 糞便懸濁ろ過用容器
SA06270191B1 (ar) 2005-06-22 2010-03-29 استرازينيكا ايه بي مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
WO2007048027A2 (en) 2005-10-21 2007-04-26 Novartis Ag Combination of a renin-inhibitor and an anti-dyslipidemic agent and/or an antiobesity agent
AR060623A1 (es) 2006-04-27 2008-07-02 Astrazeneca Ab Compuestos derivados de 2-azetidinona y un metodo de preparacion
US20100092479A1 (en) * 2008-08-18 2010-04-15 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
US20120046364A1 (en) 2009-02-10 2012-02-23 Metabasis Therapeutics, Inc. Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4602005A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis
US5063210A (en) * 1989-04-20 1991-11-05 Lange Iii Louis G Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption
WO1994000480A1 (en) * 1992-06-26 1994-01-06 Pfizer Inc. Steroidal glycosides for treating hypercholesterolemia
LT3300B (en) * 1992-12-23 1995-06-26 Schering Corp Combination of a cholesterol biosynhtesis inhibitor and a beta- lactam cholesterol absorbtion inhibitor

Also Published As

Publication number Publication date
ZA957879B (en) 1997-03-19
FI971151A7 (fi) 1997-03-19
WO1996009827A2 (en) 1996-04-04
FI971151L (fi) 1997-03-19
FI971151A0 (fi) 1997-03-19
WO1996009827A3 (en) 1996-05-23
AU2453295A (en) 1996-04-19
EP0782451A1 (en) 1997-07-09
US5807834A (en) 1998-09-15
HRP950488A2 (en) 1997-08-31
IL115310A0 (en) 1995-12-31
CA2200436A1 (en) 1996-04-04
JPH09511753A (ja) 1997-11-25
MX9702175A (es) 1997-06-28

Similar Documents

Publication Publication Date Title
BR9504072A (pt) Composiçao farmacêutica métodos para o tratamento de hipercolesterolemia de aterosclerose e kit
BR9508886A (pt) Compostos e métodos para o tratamento de câncer
BR9407799A (pt) Composição de matéria método de tratamento e composição farmaceutica
BR9407869A (pt) Combinaçao composiçao farmacêutica e processo para o tratamento de osteoporose
FI971969A0 (fi) Peräpukamien hoitoon tarkoitettuja koostumuksia ja käyttömenetelmä
FI970920L (fi) Trifenyylietyleenejä käytettäväksi osteoporoosin ehkäisyyn ja hoitoon
BR9406178A (pt) Composição de amino-açucar e glicosaminoglicano para o tratamento e restauração de tecido conectivo
BR9611986A (pt) Compostos processo para a preparação dos mesmos composição farmcéutica e utilização dos compostos
BR9612204A (pt) Composto uso do composto composição farmacêutica e processo para preparação do composto e para o tratamento de dor
BR9702147A (pt) Composição farmacéutica uso de uma composição farmacéutica e processo para o tratamento da dor associada com escarificação periodontal e para a preparação de uma composição farmacéutica
BR9709196A (pt) Derivados de azetidinona para o tratamento de aterosclerose
EE9800234A (et) Ravimeetod ja farmatseutiline kompositsioon
FI971750A0 (fi) Koostumuksia multippeliskleroosia varten ja sen hoito
FI951060L (fi) Formulaatioita ja hoitomenetelmiä
BR9509688A (pt) Composto e composição farmacêutica
PT1017388E (pt) Composicao farmaceutica contendo ibuprofeno e domperidona para o tratamento de enxaqueca
EE03783B1 (et) Farmatseutiline kompositsioon epitelioomide raviks ja antikeha või antikeha molekuli kasutamine
BR9510554A (pt) Uso de moléculas de ligação de mch-ii e/ou moléculas de imitação para a prevenção e/ou tratamento de doenças inflamatórias
BR9806083A (pt) Composi-Æo farmac-utica para o tratamento da hapattite c
DE69708418D1 (de) Naphthylverbindungen und Zusammensetzungen
PT853959E (pt) Composicao para o tratamento do amianto
PT1021200E (pt) Metodos e composicoes para o tratamento da artrite reumatoide
BR9505995A (pt) Composto método para tratamentos e composição farmacêutica
FI933642A7 (fi) Koostumus ja menetelmiä luun muodostamiseksi
BR9612206A (pt) Composto uso do composto composição farmacêutica processo para preparação do composto e para o tratamento da dor

Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B15K Others concerning applications: alteration of classification

Ipc: A61K 31/58 (2006.01), A61K 31/22 (2006.0