BR9508886A - Compostos e métodos para o tratamento de câncer - Google Patents
Compostos e métodos para o tratamento de câncerInfo
- Publication number
- BR9508886A BR9508886A BR9508886A BR9508886A BR9508886A BR 9508886 A BR9508886 A BR 9508886A BR 9508886 A BR9508886 A BR 9508886A BR 9508886 A BR9508886 A BR 9508886A BR 9508886 A BR9508886 A BR 9508886A
- Authority
- BR
- Brazil
- Prior art keywords
- cancer
- compounds
- treatment
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/301,298 US5817667A (en) | 1991-04-17 | 1994-09-06 | Compounds and methods for the treatment of cancer |
| US39063395A | 1995-02-17 | 1995-02-17 | |
| PCT/US1995/011464 WO1996007413A1 (en) | 1994-09-06 | 1995-09-05 | Compounds and methods for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9508886A true BR9508886A (pt) | 1997-12-30 |
Family
ID=26972285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9508886A BR9508886A (pt) | 1994-09-06 | 1995-09-05 | Compostos e métodos para o tratamento de câncer |
Country Status (31)
| Country | Link |
|---|---|
| US (3) | US6063787A (pt) |
| EP (2) | EP0781136B1 (pt) |
| JP (1) | JP3979662B2 (pt) |
| KR (1) | KR100374477B1 (pt) |
| CN (3) | CN1827108A (pt) |
| AP (1) | AP783A (pt) |
| AT (1) | ATE267015T1 (pt) |
| AU (1) | AU704977B2 (pt) |
| BG (1) | BG63122B1 (pt) |
| BR (1) | BR9508886A (pt) |
| CA (1) | CA2199117C (pt) |
| CZ (1) | CZ297873B6 (pt) |
| DE (1) | DE69533066T2 (pt) |
| DK (1) | DK0781136T3 (pt) |
| ES (1) | ES2219666T3 (pt) |
| FI (1) | FI970918L (pt) |
| HU (1) | HUT77172A (pt) |
| IL (1) | IL115156A (pt) |
| IS (1) | IS2011B (pt) |
| MY (1) | MY121548A (pt) |
| NO (1) | NO313268B1 (pt) |
| NZ (1) | NZ335013A (pt) |
| OA (1) | OA10473A (pt) |
| PL (2) | PL189288B1 (pt) |
| PT (1) | PT781136E (pt) |
| RO (1) | RO118748B1 (pt) |
| RU (1) | RU2168995C2 (pt) |
| SI (1) | SI0781136T1 (pt) |
| SK (1) | SK284564B6 (pt) |
| WO (1) | WO1996007413A1 (pt) |
| ZA (1) | ZA957483B (pt) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6903224B2 (en) | 1988-04-11 | 2005-06-07 | Biochem Pharma Inc. | Substituted 1,3-oxathiolanes |
| US5728575A (en) * | 1990-02-01 | 1998-03-17 | Emory University | Method of resolution of 1,3-oxathiolane nucleoside enantiomers |
| IL115156A (en) * | 1994-09-06 | 2000-07-16 | Univ Georgia | Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines |
| US6022876A (en) * | 1996-11-15 | 2000-02-08 | Yale University | L-β-dioxolane uridine analogs and methods for treating and preventing Epstein-Barr virus infections |
| WO1999008110A1 (en) | 1997-08-08 | 1999-02-18 | Newbiotics, Inc. | Methods and compositions for overcoming resistance to biologic and chemotherapy |
| JP2002500880A (ja) | 1998-01-23 | 2002-01-15 | ニューバイオティックス インコーポレイテッド | 酵素に触媒される治療剤 |
| US7462605B2 (en) | 1998-01-23 | 2008-12-09 | Celmed Oncology (Usa), Inc. | Phosphoramidate compounds and methods of use |
| BR9908270A (pt) | 1998-02-25 | 2004-06-29 | Univ Emory | 2-fluoro-nucleosìdeos, composições farmacêuticas e seus usos |
| AU2004201676B2 (en) * | 1999-03-29 | 2006-03-09 | University Of Georgia Research Foundation, Inc. | Methods of treating leukemia |
| DK1165096T3 (da) * | 1999-03-29 | 2010-01-25 | Shire Canada Inc | Anvendelse af cytidinderivater til behandling af leukæmi |
| US6653318B1 (en) | 1999-07-21 | 2003-11-25 | Yale University | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use |
| US6683061B1 (en) | 1999-07-22 | 2004-01-27 | Newbiotics, Inc. | Enzyme catalyzed therapeutic activation |
| WO2001022950A2 (en) | 1999-09-24 | 2001-04-05 | Shire Biochem Inc. | Diosolane nucleoside analogs for the treatment or prevention of viral infection |
| EP1225899A2 (en) | 1999-11-04 | 2002-07-31 | Virochem Pharma Inc. | Method for the treatment or prevention of flaviviridae viral infection using nucleoside analogues |
| EP1600451A3 (en) | 1999-11-12 | 2008-09-10 | Pharmasset, Inc. | Synthesis of 2'-deoxy-l-nucleosides |
| JP2004510832A (ja) * | 2000-10-13 | 2004-04-08 | シャイアー・バイオケム・インコーポレイテッド | 改善された細胞間送達のためのジオキソランアナログ |
| EP1359921A4 (en) | 2001-01-19 | 2006-09-06 | Newbiotics Inc | METHODS RELATING TO THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES |
| CN1744902B (zh) * | 2001-03-23 | 2010-05-26 | 希拉加拿大股份有限公司 | 治疗癌症的药物组合 |
| CA2441568A1 (en) | 2001-03-23 | 2002-10-03 | Shire Biochem Inc. | Pharmaceutical combinations for the treatment of cancer |
| AU2002242561A1 (en) * | 2001-03-30 | 2002-10-15 | Shire Biochem Inc. | Methods of treating cancer using cyplastin combined with a dioxolane nucleoside such as troxacitabine |
| AU2002336864B2 (en) * | 2001-11-02 | 2006-08-17 | Shire Biochem Inc. | Pharmaceutical compositions for the treatment of leukemia comprising dioxolane nucleosides analogs |
| IL161625A0 (en) * | 2001-11-19 | 2004-09-27 | Medigene Ag | Medicament for the treatment of viral skin and tumour diseases |
| MXPA04002365A (es) | 2002-06-21 | 2004-11-22 | Lg Electronics Inc | Medio de grabacion que tiene estructura de datos para manejar la reproduccion de datos de video grabados en el mismo. |
| CN1556988B (zh) | 2002-06-21 | 2011-09-14 | Lg电子株式会社 | 具有用于管理记录在其上面的视频数据的再现的数据结构的记录介质 |
| KR20040000290A (ko) | 2002-06-24 | 2004-01-03 | 엘지전자 주식회사 | 고밀도 광디스크의 멀티 경로 데이터 스트림 관리방법 |
| BR0305211A (pt) | 2002-06-24 | 2005-06-28 | Lg Electronics Inc | Meio de gravação possuindo estrutura de dados para gerenciamento de reprodução de dados de vìdeo de trajetória de reprodução múltipla gravados no mesmo e aparelhos e métodos de gravação e reprodução |
| KR100554767B1 (ko) | 2002-06-28 | 2006-02-22 | 엘지전자 주식회사 | 다중 경로 데이터의 기록 및 재생을 관리하기 위한 데이터구조를 갖는 기록 매체와 그에 따른 기록 및 재생 방법 및장치 |
| WO2004028542A1 (en) * | 2002-09-24 | 2004-04-08 | Novartis Ag | Use of 4-pyridylmethyl-phthalazine derivatives for the manufacture of a medicament for the treatment of myelodysplastic syndromes |
| JP4431043B2 (ja) | 2002-10-14 | 2010-03-10 | エルジー エレクトロニクス インコーポレイティド | 記録された複数のオーディオストリームの再生を管理するためのデータ構造を有する光ディスク、それによる記録及び再生方法及び装置 |
| KR100672111B1 (ko) | 2002-10-15 | 2007-01-19 | 엘지전자 주식회사 | 기록된 복수의 그래픽 스트림의 재생을 관리하기 위한데이터 구조를 갖는 기록 매체, 그에 따른 기록 및 재생방법 및 장치 |
| ES2541122T3 (es) | 2002-11-12 | 2015-07-16 | Lg Electronics Inc. | Medio de grabación que tiene una estructura de datos para gestionar la reproducción de datos de vídeo de múltiples trayectorias de reproducción grabados en el mismo y métodos y aparatos de grabación y reproducción |
| US7720356B2 (en) | 2002-11-12 | 2010-05-18 | Lg Electronics Inc | Recording medium having data structure for managing reproduction of multiple reproduction path video data recorded thereon and recording and reproducing methods and apparatuses |
| US7664372B2 (en) | 2002-11-20 | 2010-02-16 | Lg Electronics Inc. | Recording medium having data structure for managing reproduction of multiple component data recorded thereon and recording and reproducing methods and apparatuses |
| US7606463B2 (en) | 2003-02-24 | 2009-10-20 | Lg Electronics, Inc. | Recording medium having data structure for managing playback control and recording and reproducing methods and apparatuses |
| US7693394B2 (en) | 2003-02-26 | 2010-04-06 | Lg Electronics Inc. | Recording medium having data structure for managing reproduction of data streams recorded thereon and recording and reproducing methods and apparatuses |
| US7809775B2 (en) | 2003-02-27 | 2010-10-05 | Lg Electronics, Inc. | Recording medium having data structure for managing playback control recorded thereon and recording and reproducing methods and apparatuses |
| WO2004077417A1 (en) | 2003-02-28 | 2004-09-10 | Lg Electronics Inc. | Recording medium having data structure for managing random/shuffle reproduction of video data recorded thereon and recording and reproducing methods and apparatuses |
| US7620301B2 (en) | 2003-04-04 | 2009-11-17 | Lg Electronics Inc. | System and method for resuming playback |
| CA2541405C (en) | 2003-10-09 | 2014-07-29 | Medigene Ag | The use of a polyphenol for the treatment of a cancerous or pre-cancerous lesion of the skin |
| JP5149168B2 (ja) * | 2005-06-07 | 2013-02-20 | エール ユニヴァーシティ | Lfmauおよびldtを用いる癌および他の症状または病状の処置方法 |
| CN101511375B (zh) * | 2005-12-02 | 2012-09-05 | 耶鲁大学 | L-胞嘧啶核苷类似物在制备用于治疗癌症和其它病症或疾病状态的药物中的应用 |
| NO324263B1 (no) * | 2005-12-08 | 2007-09-17 | Clavis Pharma Asa | Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser |
| AU2007293377A1 (en) * | 2006-09-01 | 2008-03-13 | University Of Georgia Research Foundation, Inc. | L- OddC prodrugs for cancer |
| RU2322243C1 (ru) * | 2006-10-20 | 2008-04-20 | Наталья Юрьевна Костюкова | Фармацевтическая композиция для лечения поражений роговицы |
| CN102406649A (zh) * | 2011-11-15 | 2012-04-11 | 张始状 | 人体五种正常碱基在制备治疗肿瘤药物中的应用 |
| CN103720693A (zh) * | 2011-11-15 | 2014-04-16 | 张始状 | 人体五种正常碱基在制备治疗肿瘤药物中的应用 |
| SG10201609131YA (en) | 2016-11-01 | 2018-06-28 | Xylonix Ip Holdings Pte Ltd | Zinc-pga compositions and methods for treating cancer |
| US20190330655A1 (en) * | 2016-12-28 | 2019-10-31 | Transgene Sa | Oncolytic viruses and therapeutic molecules |
| SG10201708886RA (en) * | 2017-10-30 | 2019-05-30 | Xylonix Ip Holdings Pte Ltd | α-PGA-ZINC COMPOSITIONS AND METHODS FOR TREATING CANCER |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4000137A (en) * | 1975-06-10 | 1976-12-28 | American Home Products Corporation | Antitumor derivatives of periodate-oxidized nucleosides |
| JPS5668674A (en) * | 1979-11-08 | 1981-06-09 | Shionogi & Co Ltd | 5-fluorouracil derivative |
| PT82580B (pt) * | 1985-05-15 | 1989-01-17 | Wellcome Found | Processo para a preparacao de 2',3'- didesoxinucleosidos e de composicoes farmaceuticas que os contem |
| WO1987001284A1 (en) * | 1985-08-26 | 1987-03-12 | United States Of America, Represented By The Unite | Inhibition of in vitro infectivity and cytopathic effect of htlv-iii/lav by 2',3'-dideoxynosine, 2',3'-dideoxyguanosine, or 2',3'-dideoxyadenosine |
| US4879277A (en) * | 1985-08-26 | 1989-11-07 | The United States Of America As Represented By The Department Of Health And Human Services | Antiviral compositions and methods |
| DE3650741T2 (de) * | 1985-09-17 | 2000-10-12 | The Wellcome Foundation Ltd., Greenford | Kombination therapeutische Nukleoside mit weiteren therapeutisch wirksamen Komponenten. |
| IN164556B (pt) * | 1986-03-06 | 1989-04-08 | Takeda Chemical Industries Ltd | |
| US4916122A (en) * | 1987-01-28 | 1990-04-10 | University Of Georgia Research Foundation, Inc. | 3'-Azido-2',3'-dideoxyuridine anti-retroviral composition |
| FR2601385B1 (fr) * | 1986-07-09 | 1989-09-29 | Sucre Rech & Dev | Procede de preparation a partir de saccharose d'un melange de sucres a haute teneur en isomaltose par voie enzymatique et produits obtenus |
| US4963533A (en) * | 1986-10-24 | 1990-10-16 | Stichting Rega Vzw (Rega) | Therapeutic application of dideoxycytidinene |
| US5215971A (en) * | 1986-12-19 | 1993-06-01 | Medivir Ab | Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides |
| ATE108183T1 (de) * | 1987-03-24 | 1994-07-15 | Nycomed Imaging As | 2',3'-dideoxyribofuranoxid-derivate. |
| US5185437A (en) * | 1987-04-09 | 1993-02-09 | Burroughs Wellcome Co. | Therapeutic nucleosides |
| US5270315A (en) * | 1988-04-11 | 1993-12-14 | Biochem Pharma Inc. | 4-(purinyl bases)-substituted-1,3-dioxlanes |
| US5047407A (en) * | 1989-02-08 | 1991-09-10 | Iaf Biochem International, Inc. | 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties |
| US5041449A (en) * | 1988-04-11 | 1991-08-20 | Iaf Biochem International, Inc. | 4-(nucleoside base)-substituted-1,3-dioxolanes useful for treatment of retroviral infections |
| US5466806A (en) * | 1989-02-08 | 1995-11-14 | Biochem Pharma Inc. | Processes for preparing substituted 1,3-oxathiolanes with antiviral properties |
| NZ228645A (en) * | 1988-04-11 | 1991-09-25 | Iaf Biochem Int | 1,3-dioxolane derivatives substituted in the 5th position by a purine or pyrimidine radical; treatment of viral infections |
| US4900828A (en) * | 1988-05-12 | 1990-02-13 | Hoffmann-Laroche Inc. | Intermediate compounds and an improved procedure for the synthesis of 2',3'-dideoxycytidine |
| SE8802687D0 (sv) * | 1988-07-20 | 1988-07-20 | Astra Ab | Nucleoside derivatives |
| EP0375329B1 (en) * | 1988-12-19 | 1995-05-31 | The Wellcome Foundation Limited | Antiviral pyrimidine and purine compounds, process for their preparation and pharmaceutical compositions containing them |
| UA45942A (uk) * | 1989-02-08 | 2002-05-15 | Біокем Фарма, Інк. | 1,3-оксатіолан, його похідні, спосіб (варіанти) його одержання та фармацевтична композиція |
| NZ233197A (en) * | 1989-04-13 | 1991-11-26 | Richard Thomas Walker | Aromatically substituted nucleotide derivatives, intermediates therefor and pharmaceutical compositions |
| US5059690A (en) * | 1990-03-01 | 1991-10-22 | E. R. Squibb & Sons, Inc. | Purinyl tetrahydrofurans |
| US5071983A (en) * | 1989-10-06 | 1991-12-10 | Burroughs Wellcome Co. | Therapeutic nucleosides |
| US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
| IE904378A1 (en) * | 1989-12-20 | 1991-07-03 | Abbott Lab | Analogs of oxetanyl purines and pyrimidines |
| US5276151A (en) * | 1990-02-01 | 1994-01-04 | Emory University | Method of synthesis of 1,3-dioxolane nucleosides |
| US5700937A (en) * | 1990-02-01 | 1997-12-23 | Emory University | Method for the synthesis, compositions and use of 2'-deoxy-5-fluoro-3'-thiacytidine and related compounds |
| US5204466A (en) * | 1990-02-01 | 1993-04-20 | Emory University | Method and compositions for the synthesis of bch-189 and related compounds |
| US5527782A (en) * | 1990-03-13 | 1996-06-18 | Acic (Canada) Inc. | 5-halo-2,3'-O-cyclocytidines |
| GB9009861D0 (en) * | 1990-05-02 | 1990-06-27 | Glaxo Group Ltd | Chemical compounds |
| AU9125991A (en) * | 1990-12-05 | 1992-07-08 | University Of Georgia Research Foundation, Inc., The | Enantiomerically pure beta -l-(-)-1,3-oxathiolane nucleosides |
| US5179104A (en) * | 1990-12-05 | 1993-01-12 | University Of Georgia Research Foundation, Inc. | Process for the preparation of enantiomerically pure β-D-(-)-dioxolane-nucleosides |
| US5444063A (en) * | 1990-12-05 | 1995-08-22 | Emory University | Enantiomerically pure β-D-dioxolane nucleosides with selective anti-Hepatitis B virus activity |
| US5248776A (en) * | 1990-12-05 | 1993-09-28 | University Of Georgia Research Foundation, Inc. | Process for enantiomerically pure β-L-1,3-oxathiolane nucleosides |
| IL100502A (en) * | 1991-01-03 | 1995-12-08 | Iaf Biochem Int | PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (- |
| NZ250842A (en) * | 1991-02-22 | 1996-03-26 | Univ Emory | Resolution of a racemic mixture of nucleoside enantiomers such as 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane (ftc) |
| GB9104740D0 (en) * | 1991-03-06 | 1991-04-17 | Wellcome Found | Antiviral nucleoside combination |
| EP1142891B1 (en) * | 1991-03-06 | 2007-05-02 | Emory University | Salts and amides of (-)cis 5-Fluoro-2'-deoxy-3'-thiacytidine useful for the treatment of hepatitis B |
| US5817667A (en) * | 1991-04-17 | 1998-10-06 | University Of Georgia Research Foudation | Compounds and methods for the treatment of cancer |
| WO1992018517A1 (en) * | 1991-04-17 | 1992-10-29 | Yale University | Method of treating or preventing hepatitis b virus |
| GB9110874D0 (en) * | 1991-05-20 | 1991-07-10 | Iaf Biochem Int | Medicaments |
| ZA923641B (en) * | 1991-05-21 | 1993-02-24 | Iaf Biochem Int | Processes for the diastereoselective synthesis of nucleosides |
| GB9111902D0 (en) * | 1991-06-03 | 1991-07-24 | Glaxo Group Ltd | Chemical compounds |
| GB9116601D0 (en) * | 1991-08-01 | 1991-09-18 | Iaf Biochem Int | 1,3-oxathiolane nucleoside analogues |
| GB9226927D0 (en) | 1992-12-24 | 1993-02-17 | Iaf Biochem Int | Dideoxy nucleoside analogues |
| US5627160A (en) * | 1993-05-25 | 1997-05-06 | Yale University | L-2',3'-dideoxy nucleoside analogs as anti-hepatitis B (HBV) and anti-HIV agents |
| AU1596495A (en) * | 1993-12-30 | 1995-07-17 | Genta Incorporated | Improved process for the purification of oligomers |
| US5587362A (en) * | 1994-01-28 | 1996-12-24 | Univ. Of Ga Research Foundation | L-nucleosides |
| IL115156A (en) * | 1994-09-06 | 2000-07-16 | Univ Georgia | Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines |
| US5971983A (en) * | 1997-05-09 | 1999-10-26 | The Regents Of The University Of California | Tissue ablation device and method of use |
-
1995
- 1995-09-04 IL IL11515695A patent/IL115156A/xx not_active IP Right Cessation
- 1995-09-05 PT PT95933071T patent/PT781136E/pt unknown
- 1995-09-05 AP APAP/P/1997/000939A patent/AP783A/en active
- 1995-09-05 PL PL95358979A patent/PL189288B1/pl not_active IP Right Cessation
- 1995-09-05 PL PL95318971A patent/PL188359B1/pl not_active IP Right Cessation
- 1995-09-05 ES ES95933071T patent/ES2219666T3/es not_active Expired - Lifetime
- 1995-09-05 DE DE69533066T patent/DE69533066T2/de not_active Expired - Lifetime
- 1995-09-05 AU AU35862/95A patent/AU704977B2/en not_active Ceased
- 1995-09-05 SI SI9530703T patent/SI0781136T1/xx unknown
- 1995-09-05 EP EP95933071A patent/EP0781136B1/en not_active Expired - Lifetime
- 1995-09-05 KR KR1019970701464A patent/KR100374477B1/ko not_active Expired - Lifetime
- 1995-09-05 AT AT95933071T patent/ATE267015T1/de not_active IP Right Cessation
- 1995-09-05 DK DK95933071T patent/DK0781136T3/da active
- 1995-09-05 RO RO97-00419A patent/RO118748B1/ro unknown
- 1995-09-05 HU HU9701687A patent/HUT77172A/hu unknown
- 1995-09-05 CN CNA2006100549917A patent/CN1827108A/zh active Pending
- 1995-09-05 BR BR9508886A patent/BR9508886A/pt not_active Application Discontinuation
- 1995-09-05 CZ CZ0063397A patent/CZ297873B6/cs not_active IP Right Cessation
- 1995-09-05 WO PCT/US1995/011464 patent/WO1996007413A1/en not_active Ceased
- 1995-09-05 JP JP50970596A patent/JP3979662B2/ja not_active Expired - Lifetime
- 1995-09-05 FI FI970918A patent/FI970918L/fi unknown
- 1995-09-05 US US08/809,007 patent/US6063787A/en not_active Expired - Fee Related
- 1995-09-05 SK SK281-97A patent/SK284564B6/sk not_active IP Right Cessation
- 1995-09-05 CN CN95195621A patent/CN1111409C/zh not_active Expired - Lifetime
- 1995-09-05 CA CA002199117A patent/CA2199117C/en not_active Expired - Fee Related
- 1995-09-05 EP EP04003357A patent/EP1468687A1/en not_active Withdrawn
- 1995-09-05 RU RU97105381/04A patent/RU2168995C2/ru not_active IP Right Cessation
- 1995-09-06 MY MYPI95002637A patent/MY121548A/en unknown
- 1995-09-06 ZA ZA957483A patent/ZA957483B/xx unknown
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1997
- 1997-03-03 OA OA60972A patent/OA10473A/en unknown
- 1997-03-04 IS IS4434A patent/IS2011B/is unknown
- 1997-03-05 NO NO19971015A patent/NO313268B1/no not_active IP Right Cessation
- 1997-03-05 BG BG101284A patent/BG63122B1/xx unknown
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1999
- 1999-04-01 NZ NZ335013A patent/NZ335013A/xx not_active IP Right Cessation
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2003
- 2003-04-18 CN CNB031106706A patent/CN1251680C/zh not_active Expired - Lifetime
- 2003-08-22 US US10/646,980 patent/US7262213B2/en not_active Expired - Lifetime
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2007
- 2007-03-05 US US11/713,975 patent/US8076347B2/en not_active Expired - Lifetime
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| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
| B25G | Requested change of headquarter approved |
Owner name: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (U Free format text: A SEDE DA 2A TITULAR FOI ALTERADA, CONFORME SOLICITADO NA PETICAO NO 020050028195 DE 26/04/2005 |