BR9408378A - Composto sal farmaceuticamente aceitável composição farmacêutica e processos para o tratamento de um paciente que sofreu um derrame e que sofre de uma condição de perda progressiva de função de sistema nervoso central e para melhorar os efeitos colaterais causados em um paciente por tratamento antineoplástico de doença que produz danos oxidativos - Google Patents
Composto sal farmaceuticamente aceitável composição farmacêutica e processos para o tratamento de um paciente que sofreu um derrame e que sofre de uma condição de perda progressiva de função de sistema nervoso central e para melhorar os efeitos colaterais causados em um paciente por tratamento antineoplástico de doença que produz danos oxidativosInfo
- Publication number
- BR9408378A BR9408378A BR9408378A BR9408378A BR9408378A BR 9408378 A BR9408378 A BR 9408378A BR 9408378 A BR9408378 A BR 9408378A BR 9408378 A BR9408378 A BR 9408378A BR 9408378 A BR9408378 A BR 9408378A
- Authority
- BR
- Brazil
- Prior art keywords
- patient
- nervous system
- central nervous
- stroke
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/46—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Toxicology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/173,579 US5488145A (en) | 1993-12-23 | 1993-12-23 | 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps |
| PCT/US1994/014545 WO1995017876A2 (en) | 1993-12-23 | 1994-12-22 | 2,4-disulphophenyl butylnitrone, its salts, and their use as pharmaceutical spintraps |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9408378A true BR9408378A (pt) | 1997-08-19 |
Family
ID=22632663
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9408378A BR9408378A (pt) | 1993-12-23 | 1994-12-22 | Composto sal farmaceuticamente aceitável composição farmacêutica e processos para o tratamento de um paciente que sofreu um derrame e que sofre de uma condição de perda progressiva de função de sistema nervoso central e para melhorar os efeitos colaterais causados em um paciente por tratamento antineoplástico de doença que produz danos oxidativos |
| BR1100626-9A BR1100626A (pt) | 1993-12-23 | 1997-05-13 | Composto, sal farmaceuticamente aceitável, e, composição farmacêutica |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR1100626-9A BR1100626A (pt) | 1993-12-23 | 1997-05-13 | Composto, sal farmaceuticamente aceitável, e, composição farmacêutica |
Country Status (28)
| Country | Link |
|---|---|
| US (4) | US5488145A (pt) |
| EP (1) | EP0736004B1 (pt) |
| JP (3) | JP3412821B2 (pt) |
| KR (1) | KR100370522B1 (pt) |
| CN (1) | CN1070176C (pt) |
| AT (1) | ATE192736T1 (pt) |
| AU (1) | AU679835B2 (pt) |
| BR (2) | BR9408378A (pt) |
| CA (1) | CA2179521C (pt) |
| CZ (1) | CZ289629B6 (pt) |
| DE (1) | DE69424441T2 (pt) |
| DK (1) | DK0736004T3 (pt) |
| ES (1) | ES2145264T3 (pt) |
| FI (1) | FI111718B (pt) |
| GR (1) | GR3034134T3 (pt) |
| HR (1) | HRP950358B1 (pt) |
| HU (1) | HU221167B1 (pt) |
| MY (1) | MY114178A (pt) |
| NO (1) | NO306457B1 (pt) |
| NZ (1) | NZ279025A (pt) |
| PL (1) | PL185189B1 (pt) |
| PT (1) | PT736004E (pt) |
| RU (1) | RU2159231C2 (pt) |
| SG (1) | SG64903A1 (pt) |
| SK (1) | SK282403B6 (pt) |
| TW (1) | TW299315B (pt) |
| UA (1) | UA45964C2 (pt) |
| WO (1) | WO1995017876A2 (pt) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5723502A (en) * | 1985-07-18 | 1998-03-03 | Proctor; Peter H. | Topical spin trap composition and method |
| US5622994A (en) * | 1989-10-17 | 1997-04-22 | Oklahoma Medical Research Foundation | Spin trapping pharmaceutical compositions and methods for use thereof |
| KR960008230B1 (ko) * | 1989-10-17 | 1996-06-21 | 윌리엄 쥐.씨먼 | 중추신경계의 산화적 손상에 관련된 질병들을 억제하기 위한 조성물들 |
| US20050107366A1 (en) * | 1991-06-18 | 2005-05-19 | Carney John M. | Spin trapping pharmaceutical compositions and methods for use thereof |
| US6002001A (en) * | 1991-06-18 | 1999-12-14 | Oklahoma Medical Research Foundation | Spin trapping pharmaceutical compositions and methods for use thereof |
| US20040208875A1 (en) * | 1995-03-15 | 2004-10-21 | Queen's University At Kingston | Method for treating amyloidosis |
| US5488145A (en) * | 1993-12-23 | 1996-01-30 | Oklahoma Medical Research Foundation | 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps |
| WO1997010218A1 (en) * | 1995-09-11 | 1997-03-20 | Hoechst Marion Roussel, Inc. | Cyclic nitrones and pharmaceutical compositions containing them |
| JP3887020B2 (ja) * | 1995-11-17 | 2007-02-28 | フロリダ インターナショナル ユニバーシティー | アズレニルニトロンスピントラッピング剤、ならびにその製造方法および使用方法 |
| WO1997038683A1 (en) * | 1996-04-17 | 1997-10-23 | Oklahoma Medical Research Foundation | Nitrone free radical trap treatment of dementia associated with aids virus (hiv-1) infection |
| IL128070A0 (en) * | 1996-07-19 | 1999-11-30 | Centaur Pharmaceuticals Inc | Furan nitrone compounds |
| TW429241B (en) | 1996-09-26 | 2001-04-11 | Sumitomo Pharma | Nitrone derivatives |
| US6046232A (en) | 1997-10-17 | 2000-04-04 | Centaur Pharmaceuticals, Inc. | α-aryl-N-alkylnitrones and pharmaceutical compositions containing the same |
| US5998469A (en) * | 1998-01-16 | 1999-12-07 | Centaur Pharmaceuticals, Inc. | Thioether furan nitrone compounds |
| JP2002509147A (ja) * | 1998-01-16 | 2002-03-26 | センター ファーマシューティカルズ, インコーポレイテッド | チオフェンニトロン化合物 |
| CA2323490A1 (en) * | 1998-03-13 | 1999-09-16 | Lowell D. Waterbury | Inhibition of angiogenesis |
| US6083989A (en) * | 1999-05-18 | 2000-07-04 | Centaur Pharmaceuticals, Inc. | Aryl nitrone therapeutics for the treatment of inflammatory bowel disease |
| EP1077696A1 (en) * | 1998-05-19 | 2001-02-28 | Centaur Pharmaceuticals, Inc. | Furan nitrone therapeutics for the treatment of inflammatory bowel disease |
| UA66401C2 (en) | 1998-12-02 | 2004-05-17 | Sentor Pharmaceuticals Inc | 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical composition containing the same |
| US6730700B2 (en) * | 1998-12-02 | 2004-05-04 | Renovis, Inc. | 3,4,5,-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same |
| EP1616869B1 (en) | 1999-01-25 | 2012-04-04 | National Jewish Health | Substituted porphyrins and their therapeutic use |
| JP4726304B2 (ja) * | 1999-04-28 | 2011-07-20 | ベルス ヘルス (インターナショナル) リミティッド | アミロイドーシスを治療するための組成物および方法 |
| BR9904931A (pt) * | 1999-10-18 | 2001-06-12 | Sergio Teixeira Ferreira | Inibição de amiloidoses |
| AU1574701A (en) * | 1999-10-22 | 2001-04-30 | Wrair Walter Reed Army Institute Of Research | A pharmaceutical composition containing pglu-glu-pro-nh2 and method for treating diseases and injuries to the brain, spinal cord and retina using same |
| US6815425B1 (en) | 1999-10-22 | 2004-11-09 | The United States Of America As Represented By The Secretary Of The Army | Pharmaceutical composition containing pGLU-GLU-PRO-NH2 and method for treating diseases and injuries to the brain, spinal cord and retina using same |
| SE0000055D0 (sv) * | 2000-01-10 | 2000-01-10 | Centaur Pharmaceuticals Inc | Novel process |
| WO2001051459A1 (en) * | 2000-01-10 | 2001-07-19 | Centaur Phamaceuticals, Inc. | Method for the purification of aryl sulfonic acids and salts |
| SE0000056D0 (sv) | 2000-01-10 | 2000-01-10 | Astrazeneca Ab | Novel process |
| SE0001916D0 (sv) * | 2000-05-23 | 2000-05-23 | Astrazeneca Ab | Novel formulation |
| US6664297B1 (en) | 2000-10-18 | 2003-12-16 | Universidade Federal Do Rio De Janeiro | Methods for inhibition and dissolution of amyloidoses by administration of compositions comprising 2,4-dinitrophenol |
| AU2002253857A1 (en) | 2001-01-08 | 2002-09-04 | Centaur Pharmaceuticals, Inc. | Use of aryl nitrone compounds in methods for treating neuropathic pain |
| WO2003010154A1 (en) * | 2001-07-26 | 2003-02-06 | Samsung Electronics Co. Ltd. | Seleno compounds containing nitrone moiety, their preparation and their therapeutic uses |
| US20030045461A1 (en) * | 2001-09-06 | 2003-03-06 | Jen-Chang Hsia | Composition and methods of esterified nitroxides gated with carboxylic acids |
| FR2846968B1 (fr) * | 2002-11-08 | 2005-02-04 | Salles Jean Pierre | Nouveaux derives amphiphiles de l'alpha-c-phenyl-n-tert- butyl nitrone |
| US20070010573A1 (en) * | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| US7414076B2 (en) * | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7244764B2 (en) * | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US20050059638A1 (en) * | 2003-08-04 | 2005-03-17 | Kelly Michael G. | Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders |
| US20050182060A1 (en) * | 2004-02-13 | 2005-08-18 | Kelly Michael G. | 2-Substituted and 4-substituted aryl nitrone compounds |
| BRPI0517790A (pt) * | 2004-11-12 | 2008-10-21 | Neurochem Int Ltd | métodos e composições fluoradas para tratar doenças relacionadas à amilóide |
| CA2586334A1 (en) * | 2004-11-16 | 2006-06-08 | Neurochem (International) Limited | Compounds for the treatment of cns and amyloid associated diseases |
| CA2592320C (en) * | 2004-12-22 | 2015-11-24 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US20060235370A1 (en) * | 2005-04-04 | 2006-10-19 | Oblong John E | Method of regulating mammalian keratinous tissue |
| TW200716088A (en) * | 2005-04-15 | 2007-05-01 | Neurochem Int Ltd | Formulations and methods for treating amyloidosis |
| WO2007013842A1 (en) * | 2005-07-26 | 2007-02-01 | Astrazeneca Ab | Use of 4-((tert-butylimino)methyl) benzene-1,3-disulfonate n-oxide against maemorrhagic changes in the brain |
| WO2007013841A1 (en) * | 2005-07-26 | 2007-02-01 | Astrazeneca Ab | Use of 4-((tert-butylimine)methyl) benzene-1,3-disulfonate n-oxide against cerebral oedema |
| WO2007013844A1 (en) * | 2005-07-26 | 2007-02-01 | Astrazeneca Ab | Use of 4-[(tert-butylimino)benzene-1,3-disulfonate n-oxide against nausea |
| WO2007013843A1 (en) * | 2005-07-26 | 2007-02-01 | Astrazeneca Ab | Use of 4-[(tert-butylimino)methyl]benzene-1,3-disulfonate n-oxide against myocardial ischaemia |
| WO2007125385A2 (en) * | 2005-12-22 | 2007-11-08 | Neurochem (International) Limited | Treatment of renal disorders, diabetic nephopathy and dyslipidemias |
| AU2007277193B2 (en) * | 2006-07-25 | 2013-06-13 | Hough Ear Institute | Methods for treating acute acoustic trauma |
| KR101443573B1 (ko) | 2006-10-12 | 2014-11-03 | 비에이치아이 리미티드 파트너쉽 | 3-아미노-1-프로판설폰산을 전달하기 위한 방법, 화합물, 조성물 및 비히클 |
| EP2120905A1 (en) * | 2006-12-22 | 2009-11-25 | BELLUS Health (International) Limited | Methods, compounds, and compositions for treating metabolic disorders and diabetes |
| US20090082454A1 (en) * | 2007-09-25 | 2009-03-26 | Protia, Llc | Deuterium-enriched disufenton |
| EP2572675B1 (en) | 2007-09-26 | 2016-06-22 | St. Jude Medical, Inc. | Collapsible prosthetic heart valves |
| CN104622879A (zh) * | 2008-02-12 | 2015-05-20 | 托斯克公司 | 减少毒性的多柔比星助剂及其使用方法 |
| ES2600469T3 (es) * | 2008-05-23 | 2017-02-09 | National Jewish Health | Un compuesto para su uso en el tratamiento de lesiones asociadas con la exposición al gas fosgeno o al gas de cloro |
| AU2009288057B2 (en) * | 2008-09-02 | 2014-07-03 | Oklahoma Medical Research Foundation | 2, 4-disulfonyl pheny tert-butyl nitrone for the treatment of gliomas |
| WO2011028503A1 (en) * | 2009-08-24 | 2011-03-10 | Hough Ear Institute | Methods for treating acute acoustic trauma |
| EP2670403B1 (en) | 2011-02-04 | 2021-08-18 | Hough Ear Institute | Methods for treating brain injury |
| EP3532042A4 (en) | 2016-10-31 | 2020-06-24 | Hough Ear Institute | METHOD FOR IMPROVING SYNAPTOGENESIS AND NEURITOGENESIS |
| CN110392568A (zh) | 2017-01-19 | 2019-10-29 | 耳科制药公司 | N-乙酰半胱氨酸的制剂及其用途 |
| JP7254780B2 (ja) | 2017-09-20 | 2023-04-10 | オクラホマ・メディカル・リサーチ・ファウンデーション | 薬剤耐性神経膠腫の治療法 |
| US10829441B2 (en) | 2017-11-14 | 2020-11-10 | The University Of Toledo | Reactive oxygen species-sensitive nitric oxide synthase inhibitors for the treatment of ischemic stroke |
| EP3787750A1 (en) * | 2018-05-03 | 2021-03-10 | Hough Ear Institute | Methods for reducing accumulated pathologic tau protein |
| CA3111793A1 (en) | 2018-09-12 | 2020-03-19 | Hough Ear Institute | Methods for treating hearing loss incident to cochlear implant surgery |
| WO2021173702A1 (en) * | 2020-02-24 | 2021-09-02 | Oblato, Inc. | Compositions and methods for treating cancer and tumor |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3914650A1 (de) * | 1989-05-03 | 1990-11-08 | Basf Ag | Neue phenylendiamine sowie ein verfahren zur herstellung von phenylendiaminen |
| KR960008230B1 (ko) * | 1989-10-17 | 1996-06-21 | 윌리엄 쥐.씨먼 | 중추신경계의 산화적 손상에 관련된 질병들을 억제하기 위한 조성물들 |
| US5036097A (en) * | 1989-10-17 | 1991-07-30 | Oklahoma Medical Research Foundation | Phenylbutyl nitrone compositions and methods for prevention of gastric ulceration |
| US5025032A (en) * | 1989-10-17 | 1991-06-18 | Oklahoma Medical Research Foundation | Phenyl butyl nitrone compositions and methods for treatment of oxidative tissue damage |
| DE3937342A1 (de) * | 1989-11-09 | 1991-05-16 | Bayer Ag | Verfahren zur herstellung von 2-aminobenzol-disulfonsaeuren-(1,4) und die neue verbindung 6-chlor-2-aminobenzol-disulfonsaeure-(1,4) |
| CA2111836C (en) * | 1991-06-18 | 2006-08-29 | John M. Carney | Spin-trapping pharmaceutical compositions and methods for use thereof |
| US5488145A (en) * | 1993-12-23 | 1996-01-30 | Oklahoma Medical Research Foundation | 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps |
-
1993
- 1993-12-23 US US08/173,579 patent/US5488145A/en not_active Expired - Lifetime
-
1994
- 1994-12-22 SG SG1996007103A patent/SG64903A1/en unknown
- 1994-12-22 UA UA96072885A patent/UA45964C2/uk unknown
- 1994-12-22 AT AT95907224T patent/ATE192736T1/de not_active IP Right Cessation
- 1994-12-22 CZ CZ19961775A patent/CZ289629B6/cs not_active IP Right Cessation
- 1994-12-22 ES ES95907224T patent/ES2145264T3/es not_active Expired - Lifetime
- 1994-12-22 KR KR1019960703367A patent/KR100370522B1/ko not_active Expired - Fee Related
- 1994-12-22 BR BR9408378A patent/BR9408378A/pt not_active Application Discontinuation
- 1994-12-22 SK SK788-96A patent/SK282403B6/sk unknown
- 1994-12-22 JP JP51809895A patent/JP3412821B2/ja not_active Expired - Lifetime
- 1994-12-22 RU RU96115200/04A patent/RU2159231C2/ru not_active IP Right Cessation
- 1994-12-22 PT PT95907224T patent/PT736004E/pt unknown
- 1994-12-22 EP EP95907224A patent/EP0736004B1/en not_active Expired - Lifetime
- 1994-12-22 PL PL94315154A patent/PL185189B1/pl not_active IP Right Cessation
- 1994-12-22 DE DE69424441T patent/DE69424441T2/de not_active Expired - Fee Related
- 1994-12-22 CN CN94194993A patent/CN1070176C/zh not_active Expired - Fee Related
- 1994-12-22 CA CA002179521A patent/CA2179521C/en not_active Expired - Lifetime
- 1994-12-22 AU AU15527/95A patent/AU679835B2/en not_active Ceased
- 1994-12-22 NZ NZ279025A patent/NZ279025A/en unknown
- 1994-12-22 HU HU9601739A patent/HU221167B1/hu not_active IP Right Cessation
- 1994-12-22 DK DK95907224T patent/DK0736004T3/da active
- 1994-12-22 US US08/663,316 patent/US5780510A/en not_active Expired - Fee Related
- 1994-12-22 WO PCT/US1994/014545 patent/WO1995017876A2/en not_active Ceased
-
1995
- 1995-01-27 TW TW084100747A patent/TW299315B/zh active
- 1995-04-24 US US08/426,961 patent/US5475032A/en not_active Expired - Lifetime
- 1995-06-06 US US08/468,564 patent/US5508305A/en not_active Expired - Lifetime
- 1995-06-20 MY MYPI95001668A patent/MY114178A/en unknown
- 1995-06-23 HR HR950358A patent/HRP950358B1/xx not_active IP Right Cessation
-
1996
- 1996-06-20 NO NO962637A patent/NO306457B1/no unknown
- 1996-06-20 FI FI962589A patent/FI111718B/fi not_active IP Right Cessation
-
1997
- 1997-05-13 BR BR1100626-9A patent/BR1100626A/pt active IP Right Grant
-
2000
- 2000-05-22 JP JP2000150128A patent/JP2001010953A/ja not_active Withdrawn
- 2000-08-07 GR GR20000401829T patent/GR3034134T3/el not_active IP Right Cessation
-
2003
- 2003-12-02 JP JP2003403744A patent/JP2004075696A/ja not_active Withdrawn
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9408378A (pt) | Composto sal farmaceuticamente aceitável composição farmacêutica e processos para o tratamento de um paciente que sofreu um derrame e que sofre de uma condição de perda progressiva de função de sistema nervoso central e para melhorar os efeitos colaterais causados em um paciente por tratamento antineoplástico de doença que produz danos oxidativos | |
| CY1111088T1 (el) | Θεραπευτικη φαρμακοτεχνικη μορφη για χορηγηση τολτεροδινης με ελεγχομενη απελευθερωση | |
| ES2164040T1 (es) | Uso de agonistas del sitio de union de la glicina o de inhibidores de la absorcion de la glicina para el tratamiento de trastornos neuropsiquiatricos. | |
| ES2162615T3 (es) | Metodo para tratar o prevenir diabetes de tipo 1 mediante la administracion oral de insulina. | |
| BR9908488A (pt) | Composição farmacêutica de topiramato | |
| BR0013065A (pt) | Método e composto para tratar de uma doença associada com recrutamento e/ ou ativação aberrante de leucócitos | |
| ES2178430T3 (es) | Utilizacion de composiciones farmaceuticas gelificables en parodontologia. | |
| BRPI0011867B8 (pt) | preparação farmacêutica de levodopa/carbidopa/entacapona e processo para preparação da mesma | |
| KR940703676A (ko) | 알렌드로네이트를 사용한 치근막 질환의 치료방법(Treatment of periodontal disease with alendronate) | |
| DE69034043D1 (de) | Pcp-rezeptor-liganden und deren verwendung | |
| RU94041223A (ru) | Средство для лечения мотонейроновых заболеваний | |
| ES2170069T3 (es) | 1-alfa-hidroxiprevitamina d para administracion oral. | |
| BRPI0406883A (pt) | Composto, composição farmacêutica, método de tratar um distúrbio, e, uso de um composto | |
| BR9916114A (pt) | Uso de apomorfina na fabricação de um medicamento para tratamento de disfunção erétil orgânica masculina | |
| ES2098920T3 (es) | Formulaciones farmaceuticas para el tratamiento de la dependencia a la nicotina. | |
| ES2153906T3 (es) | Uso de incienso para el tratamiento de la enfermedad de alzheimer. | |
| KR970025615A (ko) | 암 전이 억제제 | |
| BR9607964A (pt) | Processo de preparação de um medicamento para tratar doença inflamatória do intestino | |
| ES2147788T3 (es) | 3,4-diarilcromanos para el tratamiento de la dermatitis. | |
| BR9915729A (pt) | Amidas Èmega de n-arilsulfonil-aminoácido | |
| KR910015300A (ko) | 부스피론 : 수면 무호흡증의 치료용도 | |
| DK0378146T3 (da) | Polyamin-derivater som antineoplastiske midler | |
| KR930702985A (ko) | 식도암의 치료 | |
| PT742716E (pt) | Composicao farmaceutica para administracao transdermica sistemica contendo a substancia activa morfina-6-glucuronido | |
| BR9808305A (pt) | Forma hidratada cristalina, processo para a preparação da forma hidratada cristalina, composição farmacêutica, processo de tratamento de um mamìfero, e, processo de tratamento ou de prevenção de dor. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Application withdrawn |