BR8805646A - Processo para amplificacao de genes estaveis em adn cromossomico de microorganismos procarioticos - Google Patents

Processo para amplificacao de genes estaveis em adn cromossomico de microorganismos procarioticos

Info

Publication number: BR8805646A
Authority: BR; Brazil
Prior art keywords: amplification; prokaryotic microorganisms; stable genes; chromosomic dna; chromosomic
Prior art date: 1987-02-27

Application number

BR888805646A

Other languages

English (en)

Inventor

Christiaan A G Van Eekelen

Johannes G Van Der Laan

Leonardus J S M Mulleners

Original Assignee

Gist Brocades Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-02-27

Filing date

1988-02-26

Publication date

1989-10-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8197582&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR8805646(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1988-02-26 Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv

1989-10-17 Publication of BR8805646A publication Critical patent/BR8805646A/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2414—Alpha-amylase (3.2.1.1.)
- C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Plant Pathology (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Medicinal Chemistry (AREA)
Mycology (AREA)
Tropical Medicine & Parasitology (AREA)
Virology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Enzymes And Modification Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

BR888805646A 1987-02-27 1988-02-26 Processo para amplificacao de genes estaveis em adn cromossomico de microorganismos procarioticos BR8805646A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP87200356		1987-02-27
PCT/NL1988/000006 WO1988006623A1 (en)	1987-02-27	1988-02-26	Stable gene amplification in chromosomal dna of prokaryotic microorganisms

Publications (1)

Publication Number	Publication Date
BR8805646A true BR8805646A (pt)	1989-10-17

Family

ID=8197582

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR888805646A BR8805646A (pt)	1987-02-27	1988-02-26	Processo para amplificacao de genes estaveis em adn cromossomico de microorganismos procarioticos

Country Status (20)

Country	Link
US (2)	US5733723A (pt)
EP (1)	EP0284126B1 (pt)
JP (1)	JP2637532B2 (pt)
KR (1)	KR970000188B1 (pt)
CN (1)	CN1049247C (pt)
AU (1)	AU620326B2 (pt)
BG (1)	BG60920B2 (pt)
BR (1)	BR8805646A (pt)
CA (1)	CA1327175C (pt)
DE (1)	DE3883041T2 (pt)
ES (1)	ES2045081T3 (pt)
FI (1)	FI104326B1 (pt)
HU (1)	HUT50877A (pt)
IE (1)	IE61743B1 (pt)
LT (1)	LT4001B (pt)
LV (1)	LV10791B (pt)
NO (1)	NO300382B1 (pt)
PT (1)	PT86863B (pt)
RU (1)	RU2091487C1 (pt)
WO (1)	WO1988006623A1 (pt)

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EP0896062A3 (en) *	1987-02-27	1999-04-07	Genencor International, Inc.	Transformation of alkalophilic bacillus strains
HUT50877A (en) *	1987-02-27	1990-03-28	Gist Brocades Nv	Process for producing stable gene amplification in chromosomal dna of procaryote microorganisms
US4914031A (en) *	1987-04-10	1990-04-03	Amgen, Inc.	Subtilisin analogs
US6287841B1 (en)	1988-02-11	2001-09-11	Genencor International, Inc.	High alkaline serine protease
DE69028890T2 (de) *	1989-08-11	1997-02-27	Gist Brocades Nv	Ergiebige Herstellung von Protease-Mutanten
US5695976A (en) *	1989-12-18	1997-12-09	Novo Nordisk A/S	Stable integration of DNA in bacterial genomes
JP3046344B2 (ja) *	1990-10-24	2000-05-29	塩野義製薬株式会社	新規プロテアーゼ
EP0672154A1 (en) *	1991-11-14	1995-09-20	Novo Nordisk A/S	A PROCESS FOR EXPRESSING GENES IN $i(BACILLUS LICHENIFORMIS)
DE4216246A1 (de) *	1992-05-16	1993-11-18	Solvay Enzymes Gmbh & Co Kg	Einfaches Verfahren zur stabilen chromosomalen Genamplifikation
US5395763A (en) *	1992-06-24	1995-03-07	Monsanto Company	Chromosomal expression vector
DK153992D0 (da) *	1992-12-22	1992-12-22	Novo Nordisk As	Metode
US5861273A (en) *	1993-12-21	1999-01-19	Celtrix Phamraceuticals, Inc.	Chromosomal expression of heterologous genes in bacterial cells
US6723550B1 (en)	1997-07-15	2004-04-20	Genencor International, Inc.	Proteases from gram-positive organisms
GB9724627D0 (en)	1997-11-20	1998-01-21	Genencor Int Bv	Gram positive microorganism formate pathway
GB9727470D0 (en)	1997-12-30	1998-02-25	Genencor Int Bv	Proteases from gram positive organisms
US6599731B1 (en)	1997-12-30	2003-07-29	Genencor International, Inc.	Proteases from gram positive organisms
US6465186B1 (en)	1997-12-30	2002-10-15	Genecor International, Inc.	Proteases from gram positive organisms
US6528255B1 (en)	1997-12-30	2003-03-04	Genencor International, Inc.	Proteases from gram positive organisms
US6100063A (en) *	1998-02-12	2000-08-08	Novo Nordisk A/S	Procaryotic cell comprising at least two copies of a gene
CN1160448C (zh) *	1998-02-12	2004-08-04	诺维信公司	含有两拷贝以不同方向转录之基因的原核细胞
RU2144565C1 (ru) *	1998-11-12	2000-01-20	Государственный научный центр вирусологии и биотехнологии "Вектор"	Рекомбинантная плазмидная днк pq_f35, кодирующая гибридный полипептид f 35, обладающий антигенными и иммуногенными свойствами белка vp 35 вируса марбург, способ ее получения и штамм бактерий escherichia coli - сверхпродуцент рекомбинантного полипептида f 35
US6156514A (en) *	1998-12-03	2000-12-05	Sunol Molecular Corporation	Methods for making recombinant cells
US6544792B1 (en)	1999-12-21	2003-04-08	Genencor International, Inc.	Production of secreted polypeptides
WO2002000907A1 (en) *	2000-06-23	2002-01-03	Novozymes A/S	Method for stable chromosomal multi-copy integration of genes
JP5244317B2 (ja)	2003-11-19	2013-07-24	ジェネンコー・インターナショナル・インク	セリンプロテアーゼ、セリン酵素をコードする核酸、およびこれらを取り込んだベクターおよび宿主細胞
US7985569B2 (en)	2003-11-19	2011-07-26	Danisco Us Inc.	Cellulomonas 69B4 serine protease variants
US20050227356A1 (en) *	2004-04-07	2005-10-13	Lessard Philip A	Novel compositions and methods for genetic manipulation of Rhodococcus bacteria
WO2006065272A2 (en) *	2004-05-21	2006-06-22	Idaho Research Foundation, Inc.	Methods for altering acetic acid production and enhancing cell death in bacteria
DK1766002T3 (en) *	2004-06-21	2015-12-07	Novozymes As	Stable maintenance of multiple copies of the at least two ORF in the same orientation
CN101061214B (zh)	2004-10-22	2012-12-05	诺维信公司	多个多核苷酸拷贝的稳定基因组整合
DE102007021001A1 (de)	2007-05-04	2008-11-06	Ab Enzymes Gmbh	Expressionssystem zur antibiotikafreien Produktion von Polypeptiden
CN103290048B (zh) *	2013-06-27	2015-07-15	天津科技大学	一种适用于芽孢杆菌属同源重组的质粒及工程菌
ES2855992T3 (es)	2015-12-11	2021-09-27	Wacker Chemie Ag	Cepa de microorganismos y procedimiento para la producción fermentativa exenta de antibióticos de sustancias y proteínas de bajo peso molecular
CN114032189B (zh) *	2021-05-10	2024-02-06	盐城师范学院	一种降解木质素的融合子菌株r3及其应用
GB202304540D0 (en)	2023-03-28	2023-05-10	Univ Tartu	Method of biosynthesis

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US30602A (en) *		1860-11-06		Improvement in revolver fire-arms
GB1519148A (en) *	1974-11-19	1978-07-26	Gist Brocades Nv	Compositions of matter
NO159863C (no) *	1980-01-07	1989-02-15	Univ Rochester	Fremgangsm te for fremstilling og seleksjon av en rant bakteriofag som inneholder et genetisk fragment og koder for alfa-amylase, egnet for bruk i heterolog transformering av en bacillus-verts-mikroorganisme.
IL61982A (en) *	1980-02-15	1984-01-31	Cpc International Inc	Genetically engineered microorganisms for massive production of amyloytic enzymes and process for preparing same using the corresponding recombinant dnas containing amylase coding genes
EP0074553A3 (en) *	1981-09-11	1985-01-09	The University Of Rochester	Method of increasing the yield of a product by altering a microorganism
US4617266A (en) *	1983-04-28	1986-10-14	Genex Corporation	Production of Protein A
JPS59205983A (ja) *	1983-04-28	1984-11-21	ジエネツクス・コ−ポレイシヨン	異種遺伝子を原核微生物で発現させる方法
IE81141B1 (en) *	1983-06-24	2000-04-05	Genencor Int	Procaryotic carbonyl hydrolases
AU570709B2 (en) *	1983-07-06	1988-03-24	Dsm N.V.	Cloning and expression in industrial species
FR2563533B1 (fr) *	1984-04-27	1986-08-22	Centre Nat Rech Scient	Procede d'amplification de l'expression d'un gene determine chez bacillus subtilis et souches obtenues
US4828994A (en) *	1984-09-21	1989-05-09	Genex Corporation	Bacillus strains with reduced extracellular protease levels
FR2582316B1 (fr) *	1985-05-22	1988-12-02	Centre Nat Rech Scient	Vecteurs d'expression de l'a-amylase dans bacillus subtilis, souches obtenues et procede de preparation d'a-amylase
JP2599946B2 (ja) *	1986-01-15	1997-04-16	アムジェン，インコーポレイテツド	ズブチリシン類似体
HUT50877A (en) *	1987-02-27	1990-03-28	Gist Brocades Nv	Process for producing stable gene amplification in chromosomal dna of procaryote microorganisms

1988
- 1988-02-26 HU HU881833A patent/HUT50877A/hu unknown
- 1988-02-26 WO PCT/NL1988/000006 patent/WO1988006623A1/en not_active Ceased
- 1988-02-26 JP JP63502471A patent/JP2637532B2/ja not_active Expired - Lifetime
- 1988-02-26 AU AU13981/88A patent/AU620326B2/en not_active Expired
- 1988-02-26 PT PT86863A patent/PT86863B/pt not_active IP Right Cessation
- 1988-02-26 BR BR888805646A patent/BR8805646A/pt not_active Application Discontinuation
- 1988-02-26 RU SU884356795A patent/RU2091487C1/ru active
- 1988-02-27 CN CN88101680A patent/CN1049247C/zh not_active Expired - Lifetime
- 1988-02-29 EP EP88200376A patent/EP0284126B1/en not_active Revoked
- 1988-02-29 ES ES88200376T patent/ES2045081T3/es not_active Expired - Lifetime
- 1988-02-29 CA CA000560122A patent/CA1327175C/en not_active Expired - Lifetime
- 1988-02-29 DE DE88200376T patent/DE3883041T2/de not_active Revoked
- 1988-02-29 IE IE55888A patent/IE61743B1/en not_active IP Right Cessation
- 1988-10-05 NO NO884422A patent/NO300382B1/no unknown
- 1988-10-21 KR KR88701325A patent/KR970000188B1/ko not_active Expired - Lifetime
- 1988-10-24 FI FI884903A patent/FI104326B1/fi active IP Right Grant
- 1988-10-25 BG BG085832A patent/BG60920B2/bg unknown
1993
- 1993-12-08 LV LVP-93-1313A patent/LV10791B/en unknown
1994
- 1994-01-28 LT LTIP1826A patent/LT4001B/lt not_active IP Right Cessation
- 1994-08-24 US US08/295,082 patent/US5733723A/en not_active Expired - Lifetime
1998
- 1998-03-27 US US09/049,867 patent/US6124097A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
LTIP1826A (en)	1995-08-25
US6124097A (en)	2000-09-26
CA1327175C (en)	1994-02-22
PT86863B (pt)	1992-05-29
HUT50877A (en)	1990-03-28
FI884903A7 (fi)	1988-10-24
AU620326B2 (en)	1992-02-20
KR890700664A (ko)	1989-04-26
FI104326B (fi)	1999-12-31
ES2045081T3 (es)	1994-01-16
LV10791B (en)	1995-12-20
CN1030787A (zh)	1989-02-01
RU2091487C1 (ru)	1997-09-27
WO1988006623A1 (en)	1988-09-07
FI884903A0 (fi)	1988-10-24
EP0284126B1 (en)	1993-08-11
AU1398188A (en)	1988-09-26
PT86863A (pt)	1988-03-01
KR970000188B1 (en)	1997-01-06
FI104326B1 (fi)	1999-12-31
IE880558L (en)	1988-08-27
DE3883041D1 (de)	1993-09-16
JPH01502398A (ja)	1989-08-24
US5733723A (en)	1998-03-31
LV10791A (lv)	1995-08-20
NO884422L (no)	1988-10-05
JP2637532B2 (ja)	1997-08-06
NO300382B1 (no)	1997-05-20
EP0284126A1 (en)	1988-09-28
CN1049247C (zh)	2000-02-09
IE61743B1 (en)	1994-11-30
LT4001B (en)	1996-06-25
BG60920B2 (bg)	1996-06-28
NO884422D0 (no)	1988-10-05
DE3883041T2 (de)	1994-01-20

Publication	Publication Date	Title
BR8805646A (pt)	1989-10-17	Processo para amplificacao de genes estaveis em adn cromossomico de microorganismos procarioticos
DE69627698T2 (de)	2004-01-15	Eine in kaskaden verlaufende vervielfältigungsreaktion von nukleinsäuren
BG85409A (bg)	1993-12-24	Т7 днк полимераза
ATE319854T1 (de)	2006-03-15	Enzymaktive dna moleküle
AR242987A1 (es)	1993-06-30	Secuencias de adn no codificada y genes quimicamente regulables.
IL87925A0 (en)	1989-03-31	Method for dna and rna base sequencing
FI880131A7 (fi)	1988-07-15	T7-dna-polymeras.
DE69736598D1 (de)	2006-10-12	Ribonukleaseresistente rna präparation und seine verwendung
ATE466948T1 (de)	2010-05-15	Dns-basiertes transposon-system für die einführung von nucleinsäure in die dns einer zelle
ES2104550T3 (es)	1997-10-16	Enzima purificado termoestable y proceso para amplificar, detectar y/o clonar secuencias de acido nucleico empleando dicho enzima.
FI880899L (fi)	1988-02-26	Oleellisesti puhdas DNA ja RNA ja menetelmä erytropoietiinin ekspressoimiseksi
EP0928290A4 (en)	2000-01-19	OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR THE CLIPPING OF RNS
FI924197A7 (fi)	1992-09-18	Reagensseja ja menetelmiä geeniekspression muuntamiseksi RNA:n jäljitt elyn avulla
MX9100993A (es)	1992-05-04	Secuencia de adn aislado y enzima acido 1-aminociclopropan-1-carboxilico sintasa,recombinante
DK16090A (da)	1990-01-19	Fremgangsmaade til nitrifikation og nitrogenfjernelse ved hjaelp af nitrificerende bakterier samt dertil anvendelig mikroorganisme og plasmid-dna
GB8723719D0 (en)	1987-11-11	Rna polymerase gene
ATE92963T1 (de)	1993-08-15	Stabile genamplifizierung in prokaryotischer chromosonaler dna.
MC1975A1 (fr)	1989-10-26	Adn polymerase de t7
ATE159048T1 (de)	1997-10-15	Modifizierung des zellmetabolismus durch extrazellulöse nukleasen
PT88807A (pt)	1989-07-31	Processo para a amplificacao de genes e para a preparacao melhorada de proteinas em culturas de celulas animais
KR940012633U (ko)	1994-06-18	핵산(dna) 증폭 배양기
ATE80667T1 (de)	1992-10-15	T7-dns-polymerase.
ATE104343T1 (de)	1994-04-15	T7-dns-polymerase.
IL101060A0 (en)	1992-11-15	T7 dna polymerase
GB8720381D0 (en)	1987-10-07	Hybridising probe to dna/rna target

Legal Events

Date	Code	Title
1995-08-15	FB19	Grant procedure suspended (art. 19)
1996-02-27	FB19	Grant procedure suspended (art. 19)
1998-04-07	FF	Decision: intention to grant
1999-06-22	FA11	Dismissal: dismissal - article 38, par. 2 of industrial property law