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FI880899L - Oleellisesti puhdas DNA ja RNA ja menetelmä erytropoietiinin ekspressoimiseksi - Google Patents

Oleellisesti puhdas DNA ja RNA ja menetelmä erytropoietiinin ekspressoimiseksi Download PDF

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Publication number
FI880899L
FI880899L FI880899A FI880899A FI880899L FI 880899 L FI880899 L FI 880899L FI 880899 A FI880899 A FI 880899A FI 880899 A FI880899 A FI 880899A FI 880899 L FI880899 L FI 880899L
Authority
FI
Finland
Prior art keywords
rna
substantially pure
pure dna
expressing erythropoietin
erythropoietin
Prior art date
Application number
FI880899A
Other languages
English (en)
Swedish (sv)
Other versions
FI95393C (fi
FI880899A0 (fi
FI95393B (fi
Inventor
Jerry S Powell
Original Assignee
Univ Washington
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Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25374134&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI880899(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Washington filed Critical Univ Washington
Publication of FI880899L publication Critical patent/FI880899L/fi
Publication of FI880899A0 publication Critical patent/FI880899A0/fi
Application granted granted Critical
Publication of FI95393B publication Critical patent/FI95393B/fi
Publication of FI95393C publication Critical patent/FI95393C/fi

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/505Erythropoietin [EPO]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/13011Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • C12N2795/10341Use of virus, viral particle or viral elements as a vector
    • C12N2795/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/10Plasmid DNA
    • C12N2800/108Plasmid DNA episomal vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/001Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
FI880899A 1986-06-27 1988-02-26 Oleellisesti puhdas DNA ja RNA ja menetelmä erytropoietiinin ekspressoimiseksi FI95393C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US87942386A 1986-06-27 1986-06-27
US87942386 1986-06-27
US8701459 1987-06-23
PCT/US1987/001459 WO1988000241A1 (en) 1986-06-27 1987-06-23 Human erythropoietin gene: high level expression in stably transfected mammalian cells

Publications (4)

Publication Number Publication Date
FI880899L true FI880899L (fi) 1988-02-26
FI880899A0 FI880899A0 (fi) 1988-02-26
FI95393B FI95393B (fi) 1995-10-13
FI95393C FI95393C (fi) 1996-01-25

Family

ID=25374134

Family Applications (1)

Application Number Title Priority Date Filing Date
FI880899A FI95393C (fi) 1986-06-27 1988-02-26 Oleellisesti puhdas DNA ja RNA ja menetelmä erytropoietiinin ekspressoimiseksi

Country Status (17)

Country Link
US (3) US5688679A (fi)
EP (1) EP0255231B1 (fi)
JP (1) JPS63126488A (fi)
KR (1) KR970009935B1 (fi)
CN (2) CN101041819A (fi)
AT (1) ATE76431T1 (fi)
AU (1) AU611088B2 (fi)
BR (1) BR8703269A (fi)
CA (1) CA1341361C (fi)
DE (1) DE3779206D1 (fi)
DK (1) DK173067B1 (fi)
ES (1) ES2037083T3 (fi)
FI (1) FI95393C (fi)
GR (1) GR3004707T3 (fi)
NO (1) NO303398B1 (fi)
PT (1) PT85193B (fi)
WO (1) WO1988000241A1 (fi)

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US6692737B1 (en) 1991-11-05 2004-02-17 Transkaryotic Therapies, Inc. In vivo protein production and delivery system for gene therapy
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PT101031B (pt) 1991-11-05 2002-07-31 Transkaryotic Therapies Inc Processo para o fornecimento de proteinas por terapia genetica
US5641670A (en) * 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
US5733761A (en) * 1991-11-05 1998-03-31 Transkaryotic Therapies, Inc. Protein production and protein delivery
US6054288A (en) * 1991-11-05 2000-04-25 Transkaryotic Therapies, Inc. In vivo protein production and delivery system for gene therapy
US6531124B1 (en) 1992-07-10 2003-03-11 Transkaryotic Therapies, Inc. In vivo production and delivery of insulinotropin for gene therapy
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Also Published As

Publication number Publication date
WO1988000241A1 (en) 1988-01-14
CN87104424A (zh) 1988-04-27
KR880007726A (ko) 1988-08-29
EP0255231B1 (en) 1992-05-20
BR8703269A (pt) 1988-03-15
US20020045255A1 (en) 2002-04-18
NO303398B1 (no) 1998-07-06
CN1044133C (zh) 1999-07-14
DK309387A (da) 1987-12-28
US5688679A (en) 1997-11-18
US20020137145A1 (en) 2002-09-26
FI95393C (fi) 1996-01-25
CN101041819A (zh) 2007-09-26
JPS63126488A (ja) 1988-05-30
DE3779206D1 (de) 1992-06-25
EP0255231A1 (en) 1988-02-03
GR3004707T3 (fi) 1993-04-28
DK309387D0 (da) 1987-06-17
KR970009935B1 (ko) 1997-06-19
NO880863L (no) 1988-04-26
FI880899A0 (fi) 1988-02-26
ES2037083T3 (es) 1993-06-16
FI95393B (fi) 1995-10-13
US6867020B2 (en) 2005-03-15
AU611088B2 (en) 1991-06-06
NO880863D0 (no) 1988-02-26
ATE76431T1 (de) 1992-06-15
US6682910B2 (en) 2004-01-27
PT85193B (pt) 1990-08-31
PT85193A (en) 1987-07-01
DK173067B1 (da) 1999-12-13
AU7475787A (en) 1988-01-07
CA1341361C (en) 2002-05-21

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