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BR0110331A - Substâncias que mimetizam beta que têm uma atividade de longa duração, processos para prepará-las e o uso das mesmas como medicamentos - Google Patents

Substâncias que mimetizam beta que têm uma atividade de longa duração, processos para prepará-las e o uso das mesmas como medicamentos

Info

Publication number
BR0110331A
BR0110331A BR0110331-8A BR0110331A BR0110331A BR 0110331 A BR0110331 A BR 0110331A BR 0110331 A BR0110331 A BR 0110331A BR 0110331 A BR0110331 A BR 0110331A
Authority
BR
Brazil
Prior art keywords
beta
substances
processes
long
nitrogen
Prior art date
Application number
BR0110331-8A
Other languages
English (en)
Inventor
Kurt Schromm
Alexander Walland
Karl-Heinz Bozung
Hermann Schollenberger
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ECSP003424 external-priority patent/ECSP003424A/es
Priority claimed from DE2000151318 external-priority patent/DE10051318A1/de
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of BR0110331A publication Critical patent/BR0110331A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • H—ELECTRICITY
    • H03—ELECTRONIC CIRCUITRY
    • H03F—AMPLIFIERS
    • H03F2200/00—Indexing scheme relating to amplifiers
    • H03F2200/331—Sigma delta modulation being used in an amplifying circuit

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"SUBSTâNCIAS QUE MIMETIZAM BETA QUE TêM UMA ATIVIDADE DE LONGA DURAçãO, PROCESSOS PARA PREPARá-LAS E O USO DAS MESMAS COMO MEDICAMENTOS". A invenção refere-se a novas substâncias que mimetizam beta da fórmula geral (1), em que R^ 1^ representa um grupo (a), em que R^ 3^ representa benzila, que pode opcionalmente ser substituído por metóxi, R^ 4^ representa hidrogênio, ou R^ 3^ e R^ 4^ juntos representam uma ponte -CO-CH~ 2~-O-, sendo que o grupo carbonila desta ponte está ligado ao nitrogênio; R^ 2^ representa um grupo selecionado entre (b) e (c), sendo que R^ 5^ representa dimetilamino, metóxi ou butóxi, X representa um nitrogênio ou um carbono, R^ 6^ representa metoxifenila se X representa nitrogênio, ou se X é carbono um anel fenila anelado que também está ligado a X. A invenção também refere-se a um processo para a produção das ditas substâncias que mimetizam beta e para uso das mesmas como medicamentos.
BR0110331-8A 2000-04-27 2001-04-14 Substâncias que mimetizam beta que têm uma atividade de longa duração, processos para prepará-las e o uso das mesmas como medicamentos BR0110331A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ECSP003424 ECSP003424A (es) 2000-04-27 2000-04-27 NUEVAS COMPOSICIONES DE MEDICAMENTOS A BASE DE COMPUESTOS ANTICOLINERGICAMENTE ACTIVOS Y ß-MIMETICOS
DE2000151318 DE10051318A1 (de) 2000-10-17 2000-10-17 Neu, langwirksame Betamimetika, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
PCT/EP2001/004278 WO2001083462A1 (de) 2000-04-27 2001-04-14 Neue, langwirksame betamimetika, verfahren zu deren herstellung und deren verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
BR0110331A true BR0110331A (pt) 2003-01-07

Family

ID=40317111

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0110331-8A BR0110331A (pt) 2000-04-27 2001-04-14 Substâncias que mimetizam beta que têm uma atividade de longa duração, processos para prepará-las e o uso das mesmas como medicamentos

Country Status (23)

Country Link
US (2) US20020022625A1 (pt)
EP (1) EP1305300A1 (pt)
JP (1) JP2003533448A (pt)
KR (1) KR20020093083A (pt)
CN (1) CN1426401A (pt)
AR (1) AR035637A1 (pt)
AU (1) AU5629301A (pt)
BG (1) BG107120A (pt)
BR (1) BR0110331A (pt)
CA (1) CA2405745A1 (pt)
CZ (1) CZ20023537A3 (pt)
EA (1) EA200201056A1 (pt)
EE (1) EE200200602A (pt)
HR (1) HRP20020845A2 (pt)
HU (1) HUP0300832A2 (pt)
IL (1) IL152140A0 (pt)
MX (1) MXPA02010179A (pt)
NO (1) NO20025133L (pt)
NZ (1) NZ522677A (pt)
PL (1) PL362868A1 (pt)
SK (1) SK15382002A3 (pt)
WO (1) WO2001083462A1 (pt)
YU (1) YU79502A (pt)

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FR2648709A1 (fr) * 1989-06-23 1990-12-28 Boehringer Ingelheim France Nouvelle utilisation de derives de 1-phenyl-2-aminoethanol en tant que moyens cicatrisants
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DE4108393A1 (de) * 1991-03-15 1992-09-17 Boehringer Ingelheim Kg Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln
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DE19515625C2 (de) * 1995-04-28 1998-02-19 Boehringer Ingelheim Kg Verfahren zur Herstellung von enantiomerenreinen Tropasäureestern
US6506900B1 (en) * 2001-01-31 2003-01-14 Boehringer Ingelheim Pharma Ag Process for preparing a scopine ester intermediate
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CA2405745A1 (en) 2001-11-08
PL362868A1 (en) 2004-11-02
MXPA02010179A (es) 2003-04-25
EP1305300A1 (de) 2003-05-02
CN1426401A (zh) 2003-06-25
NO20025133D0 (no) 2002-10-25
NO20025133L (no) 2002-10-25
AR035637A1 (es) 2004-06-23
EE200200602A (et) 2004-04-15
EA200201056A1 (ru) 2003-04-24
BG107120A (bg) 2003-05-30
KR20020093083A (ko) 2002-12-12
US20050137242A1 (en) 2005-06-23
NZ522677A (en) 2004-10-29
YU79502A (sh) 2006-05-25
SK15382002A3 (sk) 2003-03-04
IL152140A0 (en) 2003-05-29
HUP0300832A2 (hu) 2003-08-28
US20020022625A1 (en) 2002-02-21
JP2003533448A (ja) 2003-11-11
WO2001083462A1 (de) 2001-11-08

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