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BR0003848A - Compostos de piridina, processo para sua preparação e composições farmacêuticas que os contêm - Google Patents

Compostos de piridina, processo para sua preparação e composições farmacêuticas que os contêm

Info

Publication number
BR0003848A
BR0003848A BR0003848-2A BR0003848A BR0003848A BR 0003848 A BR0003848 A BR 0003848A BR 0003848 A BR0003848 A BR 0003848A BR 0003848 A BR0003848 A BR 0003848A
Authority
BR
Brazil
Prior art keywords
group
preparation
pharmaceutical compositions
compounds
pyridine compounds
Prior art date
Application number
BR0003848-2A
Other languages
English (en)
Inventor
Jean-Louis Peglion
Aimee Dessinges
Christophe Poitevin
Mark Millan
Anne Dekeyne
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of BR0003848A publication Critical patent/BR0003848A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Patente de Invenção: <B>"COMPOSTOS DE PIRIDINA, PROCESSO PARA SUA PREPARAçãO E COMPOSIçõES FARMACêUTICAS QUE OS CONTêM"<D>. Esta invenção refere-se a compostos de fórmula (I): onde: W representa um grupo naftila opcionalmente substituído ou um grupo de fórmula Y (onde ) como definido na descrição, n representa um número inteiro de 1 a 6 inclusive, Z representa uma ligação simples, um átomo de oxigênio ou um átomo de nitrogênio opcionalmente, A e Q representam cada um grupo CH ou um átomo de nitrogênio, M, juntamente com os átomos de carbono do anel fenila aos quais se liga, representa um grupo tienila, furila, pirrolila ou oxopirrolila, seus isómeros e também sais de adição dos compostos com um ácido ou base farmaceuticamente aceitáveis. Medicamentos.
BR0003848-2A 1999-08-27 2000-08-28 Compostos de piridina, processo para sua preparação e composições farmacêuticas que os contêm BR0003848A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9910834A FR2797874B1 (fr) 1999-08-27 1999-08-27 Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
BR0003848A true BR0003848A (pt) 2001-04-03

Family

ID=9549376

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0003848-2A BR0003848A (pt) 1999-08-27 2000-08-28 Compostos de piridina, processo para sua preparação e composições farmacêuticas que os contêm

Country Status (22)

Country Link
US (2) US6399616B1 (pt)
EP (1) EP1078928B1 (pt)
JP (1) JP3602780B2 (pt)
KR (1) KR100450317B1 (pt)
CN (1) CN1163495C (pt)
AT (1) ATE266664T1 (pt)
AU (1) AU765661B2 (pt)
BR (1) BR0003848A (pt)
CA (1) CA2317053A1 (pt)
DE (1) DE60010596T2 (pt)
DK (1) DK1078928T3 (pt)
EA (1) EA004102B1 (pt)
ES (1) ES2220359T3 (pt)
FR (1) FR2797874B1 (pt)
HU (1) HUP0003413A3 (pt)
MX (1) MXPA00008241A (pt)
NO (1) NO316651B1 (pt)
NZ (1) NZ506560A (pt)
PL (1) PL342178A1 (pt)
PT (1) PT1078928E (pt)
SI (1) SI1078928T1 (pt)
ZA (1) ZA200004411B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2797874B1 (fr) * 1999-08-27 2002-03-29 Adir Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE10031391A1 (de) * 2000-07-03 2002-02-07 Knoll Ag Bicyclische Verbindungen und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
US20040106635A1 (en) * 2001-03-29 2004-06-03 Iwao Takamuro Spiroisoquinoline compound, a method for preparing the same and an intermediate thereof
DE10217006A1 (de) * 2002-04-16 2003-11-06 Merck Patent Gmbh Substituierte Indole
US7645886B2 (en) * 2002-12-20 2010-01-12 Ciba Specialty Corporation Synthesis of amines and intermediates for the synthesis thereof
JP4559749B2 (ja) * 2004-02-16 2010-10-13 あすか製薬株式会社 ピペラジニルピリジン誘導体
JP4596792B2 (ja) * 2004-02-24 2010-12-15 あすか製薬株式会社 ５−ｈｔ１ａ作動作用と５−ｈｔ３拮抗作用を併有する薬剤
WO2005082887A1 (ja) 2004-02-26 2005-09-09 Aska Pharmaceutical Co., Ltd. ピリミジン誘導体
DE102004023508A1 (de) * 2004-05-10 2005-12-08 Grünenthal GmbH Säurederivate substituierter Cyclohexyl-1,4-diamine
DE102004023501A1 (de) * 2004-05-10 2005-12-01 Grünenthal GmbH Oxosubstituierte Cyclohexyl-1,4-diamin-Derivate
DE102004023506A1 (de) * 2004-05-10 2005-12-01 Grünenthal GmbH Kettenverlängerte substituierte Cyclohexyl-1,4-diamin-Derivate
JP2008507492A (ja) * 2004-07-23 2008-03-13 バイエル・クロツプサイエンス・エス・アー 殺菌剤としてのｎ−［２−（４−ピリジニル）エチル］ベンズアミド誘導体
WO2006056600A1 (en) 2004-11-26 2006-06-01 Janssen Pharmaceutica N.V. Isoxazoline-indole derivatives with an improved antipsychotic and anxiolytic a ivity
FR2909670B1 (fr) * 2006-12-12 2010-07-30 Sanofi Aventis Derive fluore de quinoleine-2(1h)-one,son procede de preparation et son utilisation comme intermediaire de synthese
WO2015014256A1 (en) 2013-07-29 2015-02-05 Sunshine Lake Pharma Co., Ltd. Substituted heteroaryl compounds and methods of use thereof
JP2016540013A (ja) * 2013-12-13 2016-12-22 武田薬品工業株式会社 Ｔｌｒ阻害剤としてのピロロ［３，２−ｃ］ピリジン誘導体
US9968604B2 (en) 2015-04-16 2018-05-15 Chiesi Farmaceutici S.P.A. Chromene derivatives as phoshoinositide 3-kinases inhibitors
US10316025B2 (en) 2015-06-03 2019-06-11 Sunshine Lake Pharma Co., Ltd. Substituted piperazine compounds and methods of use and use thereof
WO2017012579A1 (zh) * 2015-07-23 2017-01-26 广东东阳光药业有限公司 取代的吲哚化合物及其使用方法和用途
US20240199555A1 (en) * 2021-03-19 2024-06-20 Centre National De La Recherche Scientifique Applications of biased ligands of the serotonin 5-ht7 receptor for the treatment of pain, multiple sclerosis and the control of thermoregulation

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US2761068A (en) * 1953-10-15 1956-08-28 Gen Electric Automatic pole figure recorder
FR2312498A1 (fr) * 1975-05-30 1976-12-24 Parcor Procede de preparation de la thieno (3,2-c) pyridine et de derives de celle-ci
FR2395271A1 (fr) * 1977-06-21 1979-01-19 Parcor Procede de preparation de thieno (2,3-c) et thieno (3,2-c) pyridines
KR830003481A (ko) * 1980-09-22 1983-06-20 미야다께 도꾸지로 6-플루오로-1,8-나프티리딘 유도체의 제조방법
AU553415B2 (en) * 1983-09-19 1986-07-17 Abbott Japan Co., Ltd. 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids
CA1278792C (en) * 1985-05-06 1991-01-08 Joseph P. Yevich Antipsychotic fused-ring pyridinylpiperazine derivatives
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FR2761071B1 (fr) * 1997-03-20 1999-12-03 Synthelabo Derives de quinolein-2(1h)-one et de dihydroquinolein-2(1h)- one, leur preparation et leur application en therapeutique
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FR2797874B1 (fr) * 1999-08-27 2002-03-29 Adir Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
EA200000792A2 (ru) 2001-04-23
FR2797874B1 (fr) 2002-03-29
US6399616B1 (en) 2002-06-04
CN1163495C (zh) 2004-08-25
SI1078928T1 (en) 2004-08-31
US6486171B2 (en) 2002-11-26
FR2797874A1 (fr) 2001-03-02
NO316651B1 (no) 2004-03-22
EA004102B1 (ru) 2003-12-25
EP1078928A1 (fr) 2001-02-28
NZ506560A (en) 2001-06-29
CN1286255A (zh) 2001-03-07
AU5364200A (en) 2001-03-01
EA200000792A3 (ru) 2001-06-25
DE60010596D1 (de) 2004-06-17
JP2001097978A (ja) 2001-04-10
ZA200004411B (en) 2001-02-28
PT1078928E (pt) 2004-09-30
HUP0003413A3 (en) 2003-11-28
US20020161228A1 (en) 2002-10-31
ES2220359T3 (es) 2004-12-16
HU0003413D0 (en) 2000-08-25
KR100450317B1 (ko) 2004-09-30
MXPA00008241A (es) 2002-08-20
PL342178A1 (en) 2001-03-12
CA2317053A1 (fr) 2001-02-27
EP1078928B1 (fr) 2004-05-12
DE60010596T2 (de) 2005-05-19
HUP0003413A2 (hu) 2001-07-30
AU765661B2 (en) 2003-09-25
DK1078928T3 (da) 2004-09-13
NO20004295L (no) 2001-02-28
HK1034250A1 (en) 2001-10-19
JP3602780B2 (ja) 2004-12-15
ATE266664T1 (de) 2004-05-15
KR20010050228A (ko) 2001-06-15
NO20004295D0 (no) 2000-08-28

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