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BG60620B1 - Метод за получаване на 23-(с долу 1-6 алкилоксим)- ll-f 28249 - Google Patents

Метод за получаване на 23-(с долу 1-6 алкилоксим)- ll-f 28249 Download PDF

Info

Publication number
BG60620B1
BG60620B1 BG92810A BG9281090A BG60620B1 BG 60620 B1 BG60620 B1 BG 60620B1 BG 92810 A BG92810 A BG 92810A BG 9281090 A BG9281090 A BG 9281090A BG 60620 B1 BG60620 B1 BG 60620B1
Authority
BG
Bulgaria
Prior art keywords
nitrobenzoyl
give
compound
mmol
alkyloxime
Prior art date
Application number
BG92810A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG92810A (bg
Inventor
Donald Maulding
Anil Kumar
Original Assignee
American Cyanamid Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Company filed Critical American Cyanamid Company
Publication of BG92810A publication Critical patent/BG92810A/bg
Publication of BG60620B1 publication Critical patent/BG60620B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Cosmetics (AREA)
  • Liquid Crystal Substances (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Lubricants (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG92810A 1989-09-11 1990-09-10 Метод за получаване на 23-(с долу 1-6 алкилоксим)- ll-f 28249 BG60620B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/405,793 US4988824A (en) 1989-09-11 1989-09-11 Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds

Publications (2)

Publication Number Publication Date
BG92810A BG92810A (bg) 1993-12-24
BG60620B1 true BG60620B1 (bg) 1995-10-31

Family

ID=23605260

Family Applications (1)

Application Number Title Priority Date Filing Date
BG92810A BG60620B1 (bg) 1989-09-11 1990-09-10 Метод за получаване на 23-(с долу 1-6 алкилоксим)- ll-f 28249

Country Status (27)

Country Link
US (1) US4988824A (de)
EP (1) EP0421081B1 (de)
JP (1) JP2939312B2 (de)
KR (1) KR0160977B1 (de)
CN (1) CN1028428C (de)
AT (1) ATE107650T1 (de)
AU (1) AU634579B2 (de)
BG (1) BG60620B1 (de)
BR (1) BR9004493A (de)
CA (1) CA2024919C (de)
DE (1) DE69010129T2 (de)
DK (1) DK0421081T3 (de)
ES (1) ES2057291T3 (de)
GE (1) GEP19981003B (de)
HU (1) HU206721B (de)
IE (1) IE66030B1 (de)
IL (1) IL95303A (de)
LV (1) LV10503B (de)
MD (1) MD425C2 (de)
NZ (1) NZ235151A (de)
PL (1) PL165332B1 (de)
PT (1) PT95242B (de)
RU (1) RU2030416C1 (de)
SI (1) SI9011711A (de)
UA (1) UA26907C2 (de)
YU (1) YU47520B (de)
ZA (1) ZA907186B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU660205B2 (en) 1991-12-23 1995-06-15 Virbac, Inc Systemic control of parasites
US5439924A (en) * 1991-12-23 1995-08-08 Virbac, Inc. Systemic control of parasites
US5478951A (en) 1994-06-22 1995-12-26 American Cyanamid Company Method for the purification of 23-E isomers of 23-imino derivatives of LL-F28249 compounds
AU695656B2 (en) 1995-02-24 1998-08-20 Novartis Tiergesundheit Ag Composition for controlling parasites
ATE214603T1 (de) * 1995-06-30 2002-04-15 American Cyanamid Co Stabile makrolide und makrolide imptstoff- zusammensetzungen
WO1999017760A2 (en) 1997-10-02 1999-04-15 Microcide Pharmaceuticals, Inc. Fungal or mammalian cell efflux pump inhibitors for enhancing susceptibility of the cell to a drug
US6762327B2 (en) 2002-04-29 2004-07-13 Wyeth Selective oxidation process with enhanced safety
US7348417B2 (en) 2003-08-07 2008-03-25 Wyeth Method of purifying moxidectin through crystallization
AU2006203349B2 (en) * 2006-05-08 2008-01-31 Wyeth Process
NZ548932A (en) * 2006-05-08 2007-01-26 Wyeth Corp Intermediates and processes using them for preparing moxidectin
AU2006100660B4 (en) * 2006-06-22 2006-10-05 Wyeth Improved oxidation process with enhanced safety and use thereof
ES2978407T3 (es) 2011-12-02 2024-09-12 Boehringer Ingelheim Vetmedica Gmbh Formulaciones de moxidectina inyectables de acción prolongada
CN104277050B (zh) * 2013-07-04 2016-05-04 北大方正集团有限公司 一种制备莫西克汀的方法
CN104017001B (zh) * 2014-06-18 2016-01-13 大连九信生物化工科技有限公司 一种化学合成莫西克汀的方法
CN104292239A (zh) * 2014-09-30 2015-01-21 大连九信生物化工科技有限公司 一种消除莫西克汀生产过程中副产物二甲基硫醚的方法
CN104628740B (zh) * 2015-02-13 2017-06-16 河北圣雪大成制药有限责任公司 一种化学合成及纯化莫西克汀的方法
CN104860961B (zh) * 2015-04-10 2017-08-04 新宇药业股份有限公司 一种制备5‑氧（对‑硝基苯甲酰）‑尼莫克汀的方法
CN106831811B (zh) * 2015-08-12 2018-10-26 内蒙古佳瑞米精细化工有限公司 一种制备高含量尼莫克汀的方法
CN114591347B (zh) * 2022-03-29 2023-03-24 河北美荷药业有限公司 莫西菌素中间体及制备方法、莫西菌素的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
ES2058082T3 (es) * 1986-09-12 1994-11-01 American Cyanamid Co Derivados 23-oxo (ceto) y 23-imino de compuestos ll-f28249.
US4855317A (en) * 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
GB8721377D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
GB8721376D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
JP2629047B2 (ja) * 1988-05-10 1997-07-09 アメリカン・サイアナミツド・カンパニー マクロライド化合物
GB8813150D0 (en) * 1988-06-03 1988-07-06 American Cyanamid Co Chemical compounds
US4900758A (en) * 1989-05-11 1990-02-13 Ici Americas Inc. Novel insecticides
EP0423445B1 (de) * 1989-09-11 1995-11-08 American Cyanamid Company 13-Alkyl-23-Imino und 13-Halo-23-Imino-Derivate von LL-F28249-Verbindungen und ihre Verwendung als Endo- und Ectoparasitizide, Insektizide, Akarizide und Nematozide Mittel

Also Published As

Publication number Publication date
HK1000095A1 (en) 1997-11-21
IE66030B1 (en) 1995-11-29
KR0160977B1 (ko) 1998-12-01
PL286824A1 (en) 1991-08-12
SI9011711A (sl) 1998-02-28
JPH03141283A (ja) 1991-06-17
CA2024919C (en) 2001-12-11
ATE107650T1 (de) 1994-07-15
YU171190A (sh) 1992-07-20
YU47520B (sh) 1995-10-03
IE903273A1 (en) 1991-03-27
HUT55019A (en) 1991-04-29
HU905842D0 (en) 1991-03-28
BR9004493A (pt) 1991-09-10
IL95303A (en) 1994-11-28
DK0421081T3 (da) 1994-07-25
AU634579B2 (en) 1993-02-25
PT95242B (pt) 1997-06-30
GEP19981003B (en) 1998-10-27
UA26907C2 (uk) 1999-12-29
PT95242A (pt) 1991-05-22
LV10503A (lv) 1995-02-20
IL95303A0 (en) 1991-06-30
US4988824A (en) 1991-01-29
CA2024919A1 (en) 1991-03-12
JP2939312B2 (ja) 1999-08-25
NZ235151A (en) 1992-11-25
EP0421081A1 (de) 1991-04-10
DE69010129D1 (de) 1994-07-28
DE69010129T2 (de) 1995-01-26
CN1051043A (zh) 1991-05-01
RU2030416C1 (ru) 1995-03-10
MD425C2 (ro) 1997-04-30
AU6236290A (en) 1991-03-14
LV10503B (en) 1996-04-20
ES2057291T3 (es) 1994-10-16
HU206721B (en) 1992-12-28
CN1028428C (zh) 1995-05-17
EP0421081B1 (de) 1994-06-22
KR910006490A (ko) 1991-04-29
PL165332B1 (pl) 1994-12-30
BG92810A (bg) 1993-12-24
ZA907186B (en) 1991-06-26

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