BG45700A3 - Метод за получаване на алфа-хетероциклично заместени толунитрили - Google Patents

Метод за получаване на алфа-хетероциклично заместени толунитрили

Info

Publication number: BG45700A3
Authority: BG; Bulgaria
Prior art keywords: tolunitrile; heterocyclic substituted; obtaining alpha; alpha; compounds
Prior art date: 1986-03-07

Application number

BG081514A

Other languages

Bulgarian (bg)

English (en)

Inventor

Robert Bowman

Ronald Steele

Leslie Browne

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-03-07

Filing date

1987-03-05

Publication date

1989-07-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25274596&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG45700(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1987-03-05 Application filed by Novartis Ag filed Critical Novartis Ag

1989-07-14 Publication of BG45700A3 publication Critical patent/BG45700A3/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Fats And Perfumes (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Hydrogenated Pyridines (AREA)
Pyrrole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Indole Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Steroid Compounds (AREA)

BG081514A 1986-03-07 1987-03-05 Метод за получаване на алфа-хетероциклично заместени толунитрили BG45700A3 (bg)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/837,489 US4749713A (en)	1986-03-07	1986-03-07	Alpha-heterocycle substituted tolunitriles

Publications (1)

Publication Number	Publication Date
BG45700A3 true BG45700A3 (bg)	1989-07-14

Family

ID=25274596

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
BG078756A BG46598A3 (bg)	1986-03-07	1987-03-05	Метод за получаване на алфа-хетероциклично заместени толунитрили
BG081515A BG45701A3 (bg)	1986-03-07	1987-03-05	Метод за получаване на алфа-хетероциклично заместени толунитрили
BG081514A BG45700A3 (bg)	1986-03-07	1987-03-05	Метод за получаване на алфа-хетероциклично заместени толунитрили
BG098212A BG61204B2 (bg)	1986-03-07	1993-11-11	Алфа-хетероциклени заместени толунитрили

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
BG078756A BG46598A3 (bg)	1986-03-07	1987-03-05	Метод за получаване на алфа-хетероциклично заместени толунитрили
BG081515A BG45701A3 (bg)	1986-03-07	1987-03-05	Метод за получаване на алфа-хетероциклично заместени толунитрили

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
BG098212A BG61204B2 (bg)	1986-03-07	1993-11-11	Алфа-хетероциклени заместени толунитрили

Country Status (36)

Country	Link
US (1)	US4749713A (xx)
EP (1)	EP0236940B3 (xx)
JP (1)	JPH0755930B2 (xx)
KR (1)	KR910000482B1 (xx)
AT (1)	ATE94873T1 (xx)
BG (4)	BG46598A3 (xx)
CA (1)	CA1316928C (xx)
CY (1)	CY1905A (xx)
CZ (3)	CZ279028B6 (xx)
DD (1)	DD264432A5 (xx)
DE (2)	DE3787480T2 (xx)
DK (1)	DK172190B1 (xx)
DZ (1)	DZ1055A1 (xx)
ES (1)	ES2059317T3 (xx)
FI (1)	FI91857C (xx)
HK (1)	HK50296A (xx)
HU (1)	HU202843B (xx)
IE (1)	IE61101B1 (xx)
IL (1)	IL81746A (xx)
LU (1)	LU90128I2 (xx)
LV (1)	LV5769B4 (xx)
MA (1)	MA20888A1 (xx)
MC (1)	MC1805A1 (xx)
MT (1)	MTP998B (xx)
MX (1)	MX5496A (xx)
MY (1)	MY102428A (xx)
NL (1)	NL970011I2 (xx)
NO (2)	NO170277C (xx)
PH (1)	PH24159A (xx)
PL (2)	PL151490B1 (xx)
PT (1)	PT84410B (xx)
RO (2)	RO101533B1 (xx)
SK (3)	SK151287A3 (xx)
SU (3)	SU1470184A3 (xx)
TN (1)	TNSN87033A1 (xx)
ZA (1)	ZA871637B (xx)

Families Citing this family (49)

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US5352795A (en) *	1986-03-07	1994-10-04	Ciba-Geigy Corporation	Alpha-heterocycle substituted tolunitriles
US5112845A (en) *	1986-03-07	1992-05-12	Ciba-Geigy Corporation	Alpha-heterocycle substituted tolunitriles
GB8714013D0 (en) *	1987-06-16	1987-07-22	Ici Plc	(substituted-aralkyl)heterocyclic compounds
DE3811574A1 (de) *	1988-03-31	1989-10-19	Schering Ag	N-substituierte imidazole, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
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DE3926365A1 (de) *	1989-08-04	1991-02-07	Schering Ag	Cycloalkylenazole, verfahren zu deren herstellung, pharmazeutische praeparate, die diese enthalten sowie ihre verwendung zur herstellung von arzneimitteln
JP2602456B2 (ja) *	1990-04-12	1997-04-23	雪印乳業株式会社	子宮内膜症治療剤
EP0457716A1 (de) *	1990-04-20	1991-11-21	Ciba-Geigy Ag	Naphthalinderivate
DE4039559A1 (de) *	1990-12-07	1992-06-11	Schering Ag	Funktionalisierte vinylazole, verfahren zu deren herstellung, pharmazeutische praeparate die diese vinylazole enthalten sowie deren verwendung zur herstellung von arzneimitteln
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DE4120107A1 (de) *	1991-06-14	1992-12-17	Schering Ag	Bicyclisch substituierte vinylimidazole, -triazole und -tetrazole
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US5426196A (en) *	1993-12-22	1995-06-20	Glaxo Inc.	Synthesis of diaryl methanes
EP0877610A4 (en) *	1996-01-30	1999-09-15	Merck & Co Inc	FARNESYL-PROTEIN TRANSFERASE INHIBITORS
WO1997027852A1 (en) *	1996-01-30	1997-08-07	Merck & Co., Inc.	Inhibitors of farnesyl-protein transferase
EP0891360A4 (en) *	1996-04-03	2002-05-15	Merck & Co Inc	INHIBITORS OF FARNESYL PROTEIN TRANSFERASE
US6063930A (en) *	1996-04-03	2000-05-16	Merck & Co., Inc.	Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
US6080870A (en) *	1996-04-03	2000-06-27	Merck & Co., Inc.	Biaryl substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
AU715658B2 (en) *	1996-04-03	2000-02-10	Merck & Co., Inc.	Inhibitors of farnesyl-protein transferase
US6858598B1 (en)	1998-12-23	2005-02-22	G. D. Searle & Co.	Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6833373B1 (en)	1998-12-23	2004-12-21	G.D. Searle & Co.	Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
MXPA03010401A (es)	2001-05-16	2004-03-09	Novartis Ag	Combinacion que comprende n-[5-[4- (4-metil- piperazino-metil) -benzoilamido] -2-metilfenil] -4-(3-piridil)-2 -pirimidin-amina, y un agente quimioterapeutico.
BR0214868A (pt) *	2001-12-11	2004-12-14	Emory Universsity	Bis-(cianofenil) metil-triazol para uso em prevenção de câncer de mama
US20060069067A1 (en) *	2002-07-30	2006-03-30	Bhatnagar Ajay S	Combination of an aromatase inhibitor with a bisphosphonate
GB0217636D0 (en) *	2002-07-30	2002-09-11	Novartis Ag	Organic compounds
JP2004196795A (ja) *	2002-12-16	2004-07-15	Wyeth	外部寄生虫駆除剤としてのｎ−フェニル−３−シクロプロピルピラゾール−４−カルボニトリル
AU2003282380A1 (en) *	2003-11-14	2004-06-06	ADIBHATLA, KALI,SATYA, Bhujanga,rao	A method for the separation of the letrozole precursor 4-1-(1,2,4-triazolyl) methyl benzonitrile from its 1,3,4-triazolyl isomer
WO2005058842A1 (en) *	2003-12-15	2005-06-30	Laboratoire Theramex	1-n-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them
CA2608904A1 (en) *	2005-07-06	2007-09-07	Sicor Inc.	Improved process for the preparation of letrozole
GT200600381A (es)	2005-08-25	2007-03-28		Compuestos organicos
US20090082413A1 (en) *	2007-09-26	2009-03-26	Protia, Llc	Deuterium-enriched letrozole
RU2425038C2 (ru) *	2009-11-27	2011-07-27	Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК")	Способ получения 1-[ди(4-цианфенил)метил]-1,2,4-триазола
EP2558098A2 (en)	2010-04-16	2013-02-20	Novartis AG	Treatment of endocrine resistant breast cancer
WO2012025762A2 (en)	2010-08-27	2012-03-01	Generics [Uk] Limited	Pure intermediate
DK2753312T3 (da)	2011-09-08	2017-02-13	Mereo Biopharma 2 Ltd	Anvendelse af en aromatase-inhibitor i behandlingen af hypogonadisme og relaterede sygdomme
MX2014014831A (es)	2012-06-08	2015-02-12	Hoffmann La Roche	Selectividad de mutante y combinaciones de un compuesto inhibidor de fosfoinositida 3 cinasa y agentes quimioterapeuticos para el tratamiento de cancer.
KR102318306B1 (ko)	2013-08-14	2021-10-28	노파르티스 아게	암의 치료를 위한 조합 요법
AR104068A1 (es)	2015-03-26	2017-06-21	Hoffmann La Roche	Combinaciones de un compuesto inhibidor de fosfoinosítido 3-cinasa y un compuesto inhibidor de cdk4/6 para el tratamiento del cáncer
GB201614179D0 (en)	2016-08-19	2016-10-05	Mereo Biopharma 2 Ltd	Dosage regimen for the treatment of endometriosis
JP2021532139A (ja)	2018-07-23	2021-11-25	エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト	Ｐｉ３ｋ阻害剤であるｇｄｃ−００７７による癌の治療方法
JP2022504388A (ja)	2018-10-08	2022-01-13	エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト	Ｐｉ３ｋアルファ阻害剤およびメトホルミンを用いたがんの処置方法
TW202133857A (zh)	2019-12-03	2021-09-16	美商建南德克公司	用於乳癌治療之組合療法
MX2023006793A (es)	2020-12-11	2023-06-20	Genentech Inc	Tratamientos conjuntos para tratamiento de cancer her2.
CN116925001B (zh) *	2023-07-26	2025-09-30	陕西师范大学	一种抗乳腺癌药物来曲唑类似物的合成方法
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US4605661A (en) *	1984-06-18	1986-08-12	Eli Lilly And Company	Aromastase inhibiting α,α-diarylimidazole-4(5)-propionitriles, α,α-diarylimidazole-4(5)-propionamides, and 4(5)-(2,2-diarylethyl)imidazoles

1986
- 1986-03-07 US US06/837,489 patent/US4749713A/en not_active Expired - Lifetime
1987
- 1987-03-02 FI FI870903A patent/FI91857C/fi not_active IP Right Cessation
- 1987-03-03 DD DD87300415A patent/DD264432A5/de not_active IP Right Cessation
- 1987-03-03 IL IL81746A patent/IL81746A/xx not_active IP Right Cessation
- 1987-03-04 DZ DZ870031A patent/DZ1055A1/fr active
- 1987-03-05 BG BG078756A patent/BG46598A3/xx unknown
- 1987-03-05 PT PT84410A patent/PT84410B/pt unknown
- 1987-03-05 MC MC871874A patent/MC1805A1/fr unknown
- 1987-03-05 EP EP87103099A patent/EP0236940B3/en not_active Expired - Lifetime
- 1987-03-05 MA MA21124A patent/MA20888A1/fr unknown
- 1987-03-05 DE DE87103099T patent/DE3787480T2/de not_active Expired - Lifetime
- 1987-03-05 CY CY190587A patent/CY1905A/xx unknown
- 1987-03-05 RO RO1987134372A patent/RO101533B1/ro unknown
- 1987-03-05 AT AT87103099T patent/ATE94873T1/de active
- 1987-03-05 PL PL1987264460A patent/PL151490B1/pl unknown
- 1987-03-05 BG BG081515A patent/BG45701A3/xx unknown
- 1987-03-05 HU HU87952A patent/HU202843B/hu unknown
- 1987-03-05 DE DE1997175016 patent/DE19775016I2/de active Active
- 1987-03-05 PL PL1987280247A patent/PL152025B1/pl unknown
- 1987-03-05 ES ES87103099T patent/ES2059317T3/es not_active Expired - Lifetime
- 1987-03-05 RO RO1987134373A patent/RO101532B1/ro unknown
- 1987-03-05 BG BG081514A patent/BG45700A3/xx unknown
- 1987-03-05 CA CA000531185A patent/CA1316928C/en not_active Expired - Lifetime
- 1987-03-06 JP JP62050446A patent/JPH0755930B2/ja not_active Expired - Lifetime
- 1987-03-06 TN TNTNSN87033A patent/TNSN87033A1/fr unknown
- 1987-03-06 KR KR1019870002004A patent/KR910000482B1/ko not_active Expired
- 1987-03-06 SK SK1512-87A patent/SK151287A3/sk unknown
- 1987-03-06 PH PH34986A patent/PH24159A/en unknown
- 1987-03-06 DK DK117687A patent/DK172190B1/da not_active IP Right Cessation
- 1987-03-06 CZ CS877368A patent/CZ279028B6/cs not_active IP Right Cessation
- 1987-03-06 NO NO870937A patent/NO170277C/no not_active IP Right Cessation
- 1987-03-06 ZA ZA871637A patent/ZA871637B/xx unknown
- 1987-03-06 SK SK7367-87A patent/SK279102B6/sk unknown
- 1987-03-06 IE IE57587A patent/IE61101B1/en not_active IP Right Cessation
- 1987-03-06 SK SK7368-87A patent/SK736887A3/sk unknown
- 1987-03-06 MX MX549687A patent/MX5496A/es unknown
- 1987-03-06 MY MYPI87000247A patent/MY102428A/en unknown
- 1987-03-06 CZ CS871512A patent/CZ279026B6/cs not_active IP Right Cessation
- 1987-03-06 SU SU874202145A patent/SU1470184A3/ru active
- 1987-03-06 MT MT998A patent/MTP998B/xx unknown
- 1987-03-06 CZ CS877367A patent/CZ279027B6/cs not_active IP Right Cessation
1988
- 1988-01-18 SU SU884203999A patent/SU1577695A3/ru active
- 1988-01-18 SU SU884203990A patent/SU1549478A3/ru active
1993
- 1993-11-11 BG BG098212A patent/BG61204B2/bg unknown
1996
- 1996-03-21 HK HK50296A patent/HK50296A/en not_active IP Right Cessation
- 1996-07-18 LV LV960274A patent/LV5769B4/xx unknown
1997
- 1997-03-03 NL NL970011C patent/NL970011I2/nl unknown
- 1997-08-20 LU LU90128C patent/LU90128I2/fr unknown
1998
- 1998-03-04 NO NO1998010C patent/NO1998010I1/no unknown

Also Published As

Publication number	Publication date
NL970011I1 (nl)	1997-05-01
MC1805A1 (fr)	1987-12-22
BG45701A3 (bg)	1989-07-14
IL81746A (en)	1992-02-16
ES2059317T3 (es)	1994-11-16
HK50296A (en)	1996-03-29
LU90128I2 (fr)	1997-10-06
PH24159A (en)	1990-03-22
SU1549478A3 (ru)	1990-03-07
ATE94873T1 (de)	1993-10-15
EP0236940B1 (en)	1993-09-22
AU604011B2 (en)	1990-12-06
TNSN87033A1 (fr)	1990-01-01
CS8707367A2 (en)	1991-02-12
PL264460A1 (en)	1988-07-21
PL152025B1 (en)	1990-10-31
JPH0755930B2 (ja)	1995-06-14
DE3787480D1 (de)	1993-10-28
DK172190B1 (da)	1997-12-22
ZA871637B (en)	1987-10-28
AU6976887A (en)	1987-09-10
SK279103B6 (sk)	1998-06-03
JPS62212369A (ja)	1987-09-18
LV5769B4 (lv)	1997-04-20
DZ1055A1 (fr)	2004-09-13
KR910000482B1 (ko)	1991-01-25
IE870575L (en)	1987-09-07
FI91857B (fi)	1994-05-13
DK117687A (da)	1987-09-08
HU202843B (en)	1991-04-29
HUT43822A (en)	1987-12-28
CS8701512A2 (en)	1991-02-12
CA1316928C (en)	1993-04-27
FI91857C (fi)	1994-08-25
CY1905A (en)	1987-03-05
SK279101B6 (sk)	1998-06-03
DK117687D0 (da)	1987-03-06
PT84410B (pt)	1989-10-04
SU1577695A3 (ru)	1990-07-07
PT84410A (en)	1987-04-01
EP0236940A3 (en)	1989-10-18
CZ279027B6 (en)	1994-11-16
SK151287A3 (en)	1998-06-03
MTP998B (en)	1987-08-21
SK736787A3 (en)	1998-06-03
NO170277C (no)	1992-09-30
RO101533B1 (en)	1992-06-25
CZ279028B6 (en)	1994-11-16
DE3787480T2 (de)	1994-02-24
LV5769A4 (lv)	1996-12-20
NO870937L (no)	1987-09-08
IE61101B1 (en)	1994-10-05
EP0236940B3 (en)	2011-03-23
DE19775016I2 (de)	2002-02-21
MY102428A (en)	1992-06-30
NO1998010I1 (no)	1998-03-04
RO101532B1 (en)	1992-11-03
PL151490B1 (en)	1990-09-28
FI870903A0 (fi)	1987-03-02
BG61204B2 (bg)	1997-02-28
EP0236940A2 (en)	1987-09-16
SK279102B6 (sk)	1998-06-03
KR870008851A (ko)	1987-10-21
MA20888A1 (fr)	1987-10-01
US4749713A (en)	1988-06-07
BG46598A3 (bg)	1990-01-15
MX5496A (es)	1993-12-01
DD264432A5 (de)	1989-02-01
NL970011I2 (nl)	1997-09-01
CS8707368A2 (en)	1991-02-12
FI870903L (fi)	1987-09-08
SK736887A3 (en)	1998-06-03
NO870937D0 (no)	1987-03-06
SU1470184A3 (ru)	1989-03-30
CZ279026B6 (en)	1994-11-16
IL81746A0 (en)	1987-10-20
NO170277B (no)	1992-06-22

Publication	Publication Date	Title
BG45700A3 (bg)	1989-07-14	Метод за получаване на алфа-хетероциклично заместени толунитрили
BG28708A3 (bg)	1980-06-16	Метод за получаване на имидазолови производни
ATE65994T1 (de)	1991-08-15	Insektentoetende pyrazoline.
FR2380266A1 (fr)	1978-09-08	Molybdates d'amines heterocycliques, procede d'obtention et application
DK142985A (da)	1985-10-01	Redox-indikatorer
BG30019A3 (bg)	1981-03-16	Метод за получаване на тризаместени 1-фенил-2,3,4,5-тетрахидро-1н- 3-бензазепини
BG31499A3 (bg)	1982-01-15	Метод за получаване на 1-винилтриазолови производни
BG38333A3 (bg)	1985-11-15	Метод за получаване на заместени фенилкарбоксиоксими
BG32115A4 (bg)	1982-05-14	Метод за получаване на хидантоини
BG28847A3 (bg)	1980-07-15	Метод за получаване на хидантоинови производни
BG35328A3 (en)	1984-03-15	Method for preparing imidodisulphamidic derivatives
BG29722A3 (bg)	1981-01-15	Метод за получаване на 2,5-дисубституирани пиримидин-4-они
BG32268A3 (bg)	1982-06-15	Метод за получаване на имидазолови производни
BG28261A3 (en)	1980-03-25	Method of obtaining of imidazol derivatives
BG41124A3 (en)	1987-04-15	Method for preparing benzamides
BG43867A3 (en)	1988-08-15	Method for preparing of 6- alpha- methylcorticoids
BG40147A3 (bg)	1986-10-15	Метод за получаване на хетероциклични съединения
DE3767287D1 (de)	1991-02-14	Potenzierung von prazosin.
BG32418A3 (en)	1982-07-15	Method for obtaining of amid derivatives of 1, 2, 3- thiadiazol- 5- carbonic acid
AU539847B2 (en)	1984-10-18	3,4,5-trihydroxypiperidine compounds
ATE69220T1 (de)	1991-11-15	Sechsgliedrige heterocyclische derivate von n'substituiertenn,n'-diacylhydrazinen.
BG36935A3 (en)	1985-02-15	Method for preparing benzodiazepine compounds
BG35749A3 (bg)	1984-06-15	Метод за получаване на 20-дихидро-20,23-дидеокситидонолид
BG29646A2 (bg)	1981-01-15	1,3-дизаместени карбамиди и 2- тиокарбамиди , метод за тяхното п получаване и приложението им
BG35032A3 (bg)	1984-01-16	Метод за получаване на 1, 1, 2- трифенилпропенови производни