[go: up one dir, main page]

BG107447A - Приложение на щамове parapoxvirus ovis при органни фибрози - Google Patents

Приложение на щамове parapoxvirus ovis при органни фибрози Download PDF

Info

Publication number
BG107447A
BG107447A BG107447A BG10744703A BG107447A BG 107447 A BG107447 A BG 107447A BG 107447 A BG107447 A BG 107447A BG 10744703 A BG10744703 A BG 10744703A BG 107447 A BG107447 A BG 107447A
Authority
BG
Bulgaria
Prior art keywords
fibrosis
manufacture
liver
preventive
cells
Prior art date
Application number
BG107447A
Other languages
Bulgarian (bg)
English (en)
Inventor
Claudia Hirth-Dietrich
Tobias Schlapp
Angela Siegling
Andreas Knorr
Olaf Weber
Gudrun Theiss
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10122233A external-priority patent/DE10122233A1/de
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of BG107447A publication Critical patent/BG107447A/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24211Parapoxvirus, e.g. Orf virus
    • C12N2710/24232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BG107447A 2000-07-11 2003-01-08 Приложение на щамове parapoxvirus ovis при органни фибрози BG107447A (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10033581 2000-07-11
DE10122233A DE10122233A1 (de) 2000-07-11 2001-05-08 Verwendung von Stämmen des Parapoxvirus ovis gegen Organfibrosen
PCT/EP2001/007978 WO2002004019A2 (de) 2000-07-11 2001-07-11 Verwendung von stämmen des parapoxvirus ovis gegen organfibrosen

Publications (1)

Publication Number Publication Date
BG107447A true BG107447A (bg) 2003-09-30

Family

ID=26006334

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107447A BG107447A (bg) 2000-07-11 2003-01-08 Приложение на щамове parapoxvirus ovis при органни фибрози

Country Status (30)

Country Link
US (1) US6632647B2 (lt)
EP (1) EP1303302B1 (lt)
JP (1) JP5106736B2 (lt)
CN (1) CN1452496B (lt)
AR (1) AR028800A1 (lt)
AU (2) AU8582701A (lt)
BG (1) BG107447A (lt)
CA (1) CA2415399C (lt)
CZ (1) CZ200372A3 (lt)
DK (1) DK200300014A (lt)
EE (1) EE200300019A (lt)
FI (1) FI20030038A7 (lt)
GB (1) GB2383752B (lt)
HK (1) HK1054330B (lt)
HR (1) HRP20030097A2 (lt)
HU (1) HU227668B1 (lt)
IL (1) IL153826A0 (lt)
LT (1) LT5064B (lt)
LU (1) LU90996B1 (lt)
LV (1) LV12991B (lt)
MA (1) MA25765A1 (lt)
MX (1) MXPA03000278A (lt)
NO (1) NO20030081D0 (lt)
NZ (1) NZ523535A (lt)
PL (1) PL360839A1 (lt)
RU (1) RU2003104522A (lt)
SE (1) SE0300033L (lt)
SI (1) SI21171A (lt)
SK (1) SK382003A3 (lt)
WO (1) WO2002004019A2 (lt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19922407A1 (de) * 1999-05-14 2000-11-16 Bayer Ag Organ-, gewebs- und zellspezifisches Immuntherapeutikum für chronische virale Infektionen, sowie entzündliche, degenerative und proliferative Erkrankungen insbesondere der Leber sowie Krebs auf der Basis von rekombinantem Parapoxvirus
US6752995B2 (en) 2002-04-15 2004-06-22 Board Of Regents, The University Of Texas System Nucleic acid and polypeptide sequences useful as adjuvants
EP1499355A4 (en) 2001-12-07 2005-10-05 Bayer Pharmaceuticals Corp USE OF PARAPOX B2L PROTEIN FOR THE TREATMENT OF CANCER AND THE MODIFICATION OF IMMUNE RESPONSES
EP1574211A1 (en) 2004-03-09 2005-09-14 Inserm Use of antagonists of the CB1 receptor for the manufacture of a composition useful for the treatment of hepatic diseases
WO2012045473A1 (en) * 2010-10-07 2012-04-12 Technische Universität München Viruses for the treatment of fibrosis
EA201891848A1 (ru) 2016-02-16 2019-02-28 Осака Юниверсити Фармацевтическая композиция для применения в лечении фиброза
TW201919675A (zh) * 2017-09-07 2019-06-01 德商艾庫瑞斯公司 使用羊副痘疹病毒(Parapoxvirus ovis;PPVO)及至少一種額外抗病毒藥之經B型肝炎病毒(HBV)感染之個體之組合療法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714665A1 (de) * 1977-04-01 1978-10-05 Mayr Anton Praeparat zur behandlung von herpes zoster und anderen herpes-infektionen, sowie verfahren zu seiner herstellung
US4360510A (en) * 1979-11-30 1982-11-23 Proctor Julian W Method for screening anti-tumor agents of the reticulo-endothelial stimulant class
US4663306A (en) * 1983-09-23 1987-05-05 Ribi Immunochem Research, Inc. Pyridine-soluble extract-refined detoxified endotoxin composition and use
DE3504940C2 (de) 1984-02-17 1997-11-06 Bayer Ag Multipotente Paramunitätsmediatoren, Verfahren zu ihrer Herstellung und diese Mediatoren enthaltende Arzneimittel
DE3816139A1 (de) * 1987-10-17 1989-04-27 Bayer Ag Verfahren zur herstellung von paramunitaetsinducern
DE4405841C1 (de) * 1994-02-23 1995-01-05 Mayr Anton Prof Dr Med Vet Dr Multipotente Paramunitätsinducer auf der Basis von Kombinationen von Pockenviruskomponenten, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
ATE203678T1 (de) * 1996-04-15 2001-08-15 Anton Prof Dr Med Vet Dr Mayr Verwendung von multipotenten paramunitätsinducern aus attenuierten, nicht-immunogenen pockenviren oder parapockenviren zur herstellung von arzneimitteln
DE19922407A1 (de) * 1999-05-14 2000-11-16 Bayer Ag Organ-, gewebs- und zellspezifisches Immuntherapeutikum für chronische virale Infektionen, sowie entzündliche, degenerative und proliferative Erkrankungen insbesondere der Leber sowie Krebs auf der Basis von rekombinantem Parapoxvirus
IL139593A (en) * 2000-11-09 2010-12-30 Biogem Optical Ltd Method for the detection of viable microorganisms

Also Published As

Publication number Publication date
GB2383752A (en) 2003-07-09
LT5064B (lt) 2003-11-25
AU8582701A (en) 2002-01-21
CN1452496B (zh) 2012-10-10
HUP0303830A2 (hu) 2004-04-28
HU227668B1 (en) 2011-11-28
NZ523535A (en) 2004-12-24
EP1303302A2 (de) 2003-04-23
MA25765A1 (fr) 2003-04-01
HK1054330A1 (en) 2003-11-28
DK200300014A (da) 2003-03-07
HUP0303830A3 (en) 2004-10-28
SI21171A (sl) 2003-10-31
HK1054330B (zh) 2005-07-15
CZ200372A3 (cs) 2003-05-14
IL153826A0 (en) 2003-07-31
EE200300019A (et) 2004-10-15
CA2415399A1 (en) 2003-01-08
US20020076418A1 (en) 2002-06-20
US6632647B2 (en) 2003-10-14
NO20030081L (no) 2003-01-08
EP1303302B1 (de) 2009-10-14
AU2001285827B2 (en) 2006-11-30
LT2003008A (lt) 2003-07-25
JP2004502741A (ja) 2004-01-29
WO2002004019A3 (de) 2002-08-01
SK382003A3 (en) 2003-07-01
LU90996B1 (en) 2003-01-08
LV12991B (en) 2003-08-20
RU2003104522A (ru) 2004-06-27
CN1452496A (zh) 2003-10-29
JP5106736B2 (ja) 2012-12-26
SE0300033D0 (sv) 2003-01-10
NO20030081D0 (no) 2003-01-08
SE0300033L (sv) 2003-03-10
GB2383752B (en) 2004-11-24
CA2415399C (en) 2011-11-08
FI20030038A7 (fi) 2003-03-10
PL360839A1 (pl) 2004-09-20
WO2002004019A2 (de) 2002-01-17
HRP20030097A2 (en) 2005-02-28
MXPA03000278A (es) 2004-04-05
AR028800A1 (es) 2003-05-21
GB0302629D0 (en) 2003-03-12

Similar Documents

Publication Publication Date Title
KR0149677B1 (ko) 안정화된 생 백신
CN102858959B (zh) 溶瘤弹状病毒
CN102803477B (zh) 新城疫病毒的新克隆、其制备及其在癌症医学治疗中的应用
BG107447A (bg) Приложение на щамове parapoxvirus ovis при органни фибрози
JP5950964B2 (ja) 臓器線維形成に対するパラポックスウイルスovis株の使用
CN114377127A (zh) 一种三联卵黄抗体制剂及其制备方法和应用
TWI807609B (zh) 乳酸菌用於提升對腸病毒71型之抵抗力之用途
KR102353119B1 (ko) 시아노박테리아 추출물, 이의 제조 방법 및 그 용도
JP7639136B2 (ja) 呼吸器ウイルス感染症の処置又は予防のためのスーパーオキシドジスムターゼ活性を有するポリペプチド及び細胞外小胞の使用
CN111329859B (zh) 叶绿素铜钠盐在制备用于抗肠道病毒的药物中的应用
HK1060050A (en) Use of strains of the parapox ovis virus against organ fibrosis
TWI803229B (zh) 一種化合物tsyi-zac用於抑制登革熱病毒感染及其醫藥治療用途
CN118526483A (zh) 一种天然植物来源的联苯多酚化合物在制备治疗疱疹性疾病的药物中的应用
WO2022000167A1 (zh) 转铁蛋白、转铁蛋白受体及其抗体在制备抗SARS-CoV-2病毒的药物中的应用
CN115475196A (zh) 腹安颗粒浸膏在制备用于治疗手足口病的药物中的用途
CN117018034A (zh) 胎盘源细胞因子在治疗和预防疱疹病毒感染及其相关疾病的应用
CN116987171A (zh) 一种用于防治疱疹病毒感染的胎盘源细胞因子制备方法及其制剂的应用
Lozitsky Anti-Infectious Actions of Proteolysis Inhibitor e-Aminocaproic Acid (ε-ACA)
Kriek IOUOnivIers~ ityIF~ ree~ St~ ate~~~~~~~~~ 34300002088221 Universiteit Vrystaat The Oncolytic Properties of Two Newcastle Disease Virus Strains.
Vivo Functional Antagonism of Chemokine