BG105365A - Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents - Google Patents

Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents

Info

Publication number: BG105365A
Authority: BG; Bulgaria
Prior art keywords: compounds; alkynyl; anticancer agents; derivatives useful; substituted quinolin
Prior art date: 1998-08-27

Application number

BG105365A

Other languages

Bulgarian (bg)

English (en)

Inventor

GRECA Susan LA

Joseph Lyssikatos

Original Assignee

Pfizer Products Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-27

Filing date

2001-03-20

Publication date

2001-11-30

2001-03-20 Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.

2001-11-30 Publication of BG105365A publication Critical patent/BG105365A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BG105365A 1998-08-27 2001-03-20 Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents BG105365A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US9814598P	1998-08-27	1998-08-27
PCT/IB1999/001398 WO2000012499A1 (en)	1998-08-27	1999-08-06	Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents

Publications (1)

Publication Number	Publication Date
BG105365A true BG105365A (en)	2001-11-30

Family

ID=22267481

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG105365A BG105365A (en)	1998-08-27	2001-03-20	Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents

Country Status (40)

Country	Link
US (3)	US6150377A (xx)
EP (1)	EP1107963B1 (xx)
JP (1)	JP3495706B2 (xx)
KR (1)	KR20010072991A (xx)
CN (1)	CN1314904A (xx)
AP (1)	AP2001002079A0 (xx)
AT (1)	ATE321037T1 (xx)
AU (1)	AU4925499A (xx)
BG (1)	BG105365A (xx)
BR (1)	BRPI9913138B8 (xx)
CA (2)	CA2578326C (xx)
CO (1)	CO5130017A1 (xx)
CZ (1)	CZ2001660A3 (xx)
DE (1)	DE69930518T2 (xx)
DZ (1)	DZ2880A1 (xx)
EA (1)	EA200100135A1 (xx)
EE (1)	EE200100118A (xx)
ES (1)	ES2259237T3 (xx)
GE (1)	GEP20033001B (xx)
GT (1)	GT199900140A (xx)
HK (1)	HK1039123A1 (xx)
HR (1)	HRP20010142A2 (xx)
HU (1)	HUP0103228A3 (xx)
ID (1)	ID27562A (xx)
IL (1)	IL141239A0 (xx)
IS (1)	IS5818A (xx)
MA (1)	MA26680A1 (xx)
NO (1)	NO20010964L (xx)
NZ (1)	NZ509372A (xx)
OA (1)	OA11645A (xx)
PA (1)	PA8480101A1 (xx)
PE (1)	PE20000986A1 (xx)
PL (1)	PL346426A1 (xx)
SK (1)	SK2442001A3 (xx)
SV (1)	SV1999000141A (xx)
TN (1)	TNSN99162A1 (xx)
TR (1)	TR200101343T2 (xx)
UY (1)	UY25682A1 (xx)
WO (1)	WO2000012499A1 (xx)
ZA (1)	ZA200101173B (xx)

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DE69923849T2 (de) *	1998-08-27	2006-01-12	Pfizer Products Inc., Groton	Quinolin-2-on-derivate verwendbar als antikrebsmittel
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1999
- 1999-08-06 IL IL14123999A patent/IL141239A0/xx unknown
- 1999-08-06 CA CA002578326A patent/CA2578326C/en not_active Expired - Fee Related
- 1999-08-06 BR BRPI9913138A patent/BRPI9913138B8/pt not_active IP Right Cessation
- 1999-08-06 AU AU49254/99A patent/AU4925499A/en not_active Abandoned
- 1999-08-06 ES ES99933084T patent/ES2259237T3/es not_active Expired - Lifetime
- 1999-08-06 AT AT99933084T patent/ATE321037T1/de not_active IP Right Cessation
- 1999-08-06 DE DE69930518T patent/DE69930518T2/de not_active Expired - Lifetime
- 1999-08-06 CN CN99810204A patent/CN1314904A/zh active Pending
- 1999-08-06 EA EA200100135A patent/EA200100135A1/ru unknown
- 1999-08-06 HR HR20010142A patent/HRP20010142A2/hr not_active Application Discontinuation
- 1999-08-06 HU HU0103228A patent/HUP0103228A3/hu unknown
- 1999-08-06 PL PL99346426A patent/PL346426A1/xx not_active Application Discontinuation
- 1999-08-06 EE EEP200100118A patent/EE200100118A/xx unknown
- 1999-08-06 TR TR2001/01343T patent/TR200101343T2/xx unknown
- 1999-08-06 JP JP2000567527A patent/JP3495706B2/ja not_active Expired - Fee Related
- 1999-08-06 ID IDW20010457A patent/ID27562A/id unknown
- 1999-08-06 NZ NZ509372A patent/NZ509372A/en unknown
- 1999-08-06 GE GEAP19995770A patent/GEP20033001B/en unknown
- 1999-08-06 CA CA002341690A patent/CA2341690C/en not_active Expired - Fee Related
- 1999-08-06 WO PCT/IB1999/001398 patent/WO2000012499A1/en not_active Ceased
- 1999-08-06 OA OA1200100051A patent/OA11645A/en unknown
- 1999-08-06 KR KR1020017002442A patent/KR20010072991A/ko not_active Ceased
- 1999-08-06 EP EP99933084A patent/EP1107963B1/en not_active Expired - Lifetime
- 1999-08-06 AP APAP/P/2001/002079A patent/AP2001002079A0/en unknown
- 1999-08-06 CZ CZ2001660A patent/CZ2001660A3/cs unknown
- 1999-08-06 HK HK02100579.7A patent/HK1039123A1/zh unknown
- 1999-08-06 SK SK244-2001A patent/SK2442001A3/sk unknown
- 1999-08-10 PA PA19998480101A patent/PA8480101A1/es unknown
- 1999-08-24 GT GT199900140A patent/GT199900140A/es unknown
- 1999-08-25 TN TNTNSN99162A patent/TNSN99162A1/fr unknown
- 1999-08-25 DZ DZ990180A patent/DZ2880A1/xx active
- 1999-08-25 MA MA25743A patent/MA26680A1/fr unknown
- 1999-08-26 PE PE1999000862A patent/PE20000986A1/es not_active Application Discontinuation
- 1999-08-26 US US09/383,755 patent/US6150377A/en not_active Expired - Lifetime
- 1999-08-27 CO CO99054519A patent/CO5130017A1/es unknown
- 1999-08-27 UY UY25682A patent/UY25682A1/es unknown
- 1999-08-27 SV SV1999000141A patent/SV1999000141A/es not_active Application Discontinuation
2000
- 2000-07-27 US US09/628,039 patent/US6294552B1/en not_active Expired - Lifetime
2001
- 2001-01-19 IS IS5818A patent/IS5818A/is unknown
- 2001-02-12 ZA ZA200101173A patent/ZA200101173B/en unknown
- 2001-02-26 NO NO20010964A patent/NO20010964L/no not_active Application Discontinuation
- 2001-03-20 BG BG105365A patent/BG105365A/xx unknown
- 2001-07-06 US US09/900,401 patent/US6579887B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
MA26680A1 (fr)	2004-12-20
BR9913138B1 (pt)	2013-11-05
HK1039123A1 (zh)	2002-04-12
KR20010072991A (ko)	2001-07-31
US6579887B2 (en)	2003-06-17
NO20010964D0 (no)	2001-02-26
EP1107963B1 (en)	2006-03-22
HUP0103228A3 (en)	2003-01-28
DE69930518D1 (de)	2006-05-11
JP3495706B2 (ja)	2004-02-09
IL141239A0 (en)	2002-03-10
DE69930518T2 (de)	2006-09-21
PL346426A1 (en)	2002-02-11
WO2000012499A1 (en)	2000-03-09
IS5818A (is)	2001-01-19
US6294552B1 (en)	2001-09-25
NZ509372A (en)	2003-08-29
BRPI9913138B8 (pt)	2016-05-17
CA2578326C (en)	2009-11-24
PA8480101A1 (es)	2003-06-30
TR200101343T2 (tr)	2001-09-21
US20020128287A1 (en)	2002-09-12
GT199900140A (es)	2001-02-14
CO5130017A1 (es)	2002-02-27
EA200100135A1 (ru)	2001-08-27
ZA200101173B (en)	2002-04-12
CA2578326A1 (en)	2000-03-09
JP2002523504A (ja)	2002-07-30
ID27562A (id)	2001-04-12
CZ2001660A3 (cs)	2002-05-15
TNSN99162A1 (fr)	2005-11-10
BR9913138A (pt)	2001-05-08
US6150377A (en)	2000-11-21
GEP20033001B (en)	2003-06-25
EE200100118A (et)	2002-06-17
NO20010964L (no)	2001-04-26
UY25682A1 (es)	2000-03-31
DZ2880A1 (fr)	2003-12-15
EP1107963A1 (en)	2001-06-20
HRP20010142A2 (en)	2002-02-28
CA2341690A1 (en)	2000-03-09
SK2442001A3 (en)	2002-10-08
CA2341690C (en)	2007-04-17
SV1999000141A (es)	2000-07-06
ATE321037T1 (de)	2006-04-15
OA11645A (en)	2004-11-16
ES2259237T3 (es)	2006-09-16
AP2001002079A0 (en)	2001-03-31
CN1314904A (zh)	2001-09-26
AU4925499A (en)	2000-03-21
PE20000986A1 (es)	2000-09-30
HUP0103228A2 (hu)	2002-02-28

Publication	Publication Date	Title
BG105365A (en)	2001-11-30	Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents
AU4925199A (en)	2000-03-21	Quinolin-2-one derivatives useful as anticancer agents
BG105860A (en)	2002-03-29	Heteroaryl-substituted quinolin-2-one derivatives useful as anticancer agents
MY124390A (en)	2006-06-30	Substituted bicyclic derivatives useful as anticancer agents
BG104998A (en)	2001-07-31	Isothiazole derivatives useful as anticancer agents
BR9805734A (pt)	2000-05-16	Derivados de imidazolin-4-ona úteis como agentes anticancerìgenos.
YU30702A (sh)	2005-06-10	Novi derivati benzoimidazola, korisni agensi protiv proliferacije
DK1029853T3 (da)	2004-05-24	Heteroaromatiske bicykliske derivativer, der er egnede som anticancermidler
MY139357A (en)	2009-09-30	Novel benzoimidazole derivatives useful as antiproliferative agents
YU95102A (sh)	2005-11-28	Supstituisani biciklični derivati u lečenju abnormalnog rasta ćelija
AP9701039A0 (en)	1997-07-31	Derivatives of 2- (2-oxo-ethlidene)-imidazolidin-4-one.
BRPI0413876A (pt)	2006-10-24	tienopiridin-fenilacetamidas e seus derivados úteis como agentes antiangiogênicos
MXPA04005157A (es)	2004-08-11	Procedimientos para la preparacion de derivados biciclicos sustituidos para el tratamiento del crecimiento celular anormal.
TR200102315T2 (tr)	2001-12-21	Antikanser maddeleri olarak faydalı heteroaril-ikame edilmiş kinolin-2- on türevleri.