AU8182775A - 8-Thiomethyl ergolines - Google Patents

8-Thiomethyl ergolines

Info

Publication number: AU8182775A
Authority: AU; Australia
Prior art keywords: ergolines; thiomethyl; thiomethyl ergolines
Prior art date: 1974-06-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

AU81827/75A

Other versions

AU507574B2 (en

Inventor

E. C. and Bach N. J Kornfeld

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-06-06

Filing date

1975-06-04

Publication date

1976-12-09

1975-06-04 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1976-12-09 Publication of AU8182775A publication Critical patent/AU8182775A/en

1980-02-21 Application granted granted Critical

1980-02-21 Publication of AU507574B2 publication Critical patent/AU507574B2/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AU81827/75A 1974-06-06 1975-06-04 8-thiomethyl ergolines Expired AU507574B2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US477136A US3901894A (en)	1974-06-06	1974-06-06	8-thiomethylergolines
USUS477136		1974-06-06

Publications (2)

Publication Number	Publication Date
AU8182775A true AU8182775A (en)	1976-12-09
AU507574B2 AU507574B2 (en)	1980-02-21

Family

ID=23894677

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU81827/75A Expired AU507574B2 (en)	1974-06-06	1975-06-04	8-thiomethyl ergolines

Country Status (27)

Country	Link
US (1)	US3901894A (en)
JP (1)	JPS582946B2 (en)
AR (1)	AR210736A1 (en)
AT (1)	AT344333B (en)
AU (1)	AU507574B2 (en)
BE (1)	BE829887A (en)
BG (1)	BG24812A3 (en)
CA (1)	CA1071623A (en)
CH (1)	CH617196A5 (en)
CS (1)	CS199591B2 (en)
DD (1)	DD120438A5 (en)
DE (1)	DE2524575A1 (en)
DK (1)	DK144160C (en)
ES (1)	ES438313A1 (en)
FR (1)	FR2273542A1 (en)
GB (1)	GB1505296A (en)
HU (1)	HU173590B (en)
IE (1)	IE41474B1 (en)
IL (1)	IL47424A (en)
NL (1)	NL180911C (en)
PH (1)	PH10992A (en)
PL (1)	PL95738B1 (en)
RO (1)	RO77543A (en)
SE (1)	SE420095B (en)
SU (1)	SU613724A3 (en)
YU (1)	YU145575A (en)
ZA (1)	ZA753638B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4147789A (en) *	1974-03-14	1979-04-03	Sandoz Ltd.	6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) *	1974-12-13	1976-05-25	Eli Lilly And Company	8-Oxymethylergolines and process therefor
JPS5283894A (en) *	1976-01-01	1977-07-13	Lilly Co Eli	88thiomethyl ergoline
GB1549829A (en) *	1976-05-26	1979-08-08	Farmaceutici Italia	10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (en) *	1977-07-05	1988-03-31	Simes	ERGOLINE-2-THIOETHERS AND THEIR SULPHOXIDES DERIVATIVES
US4166182A (en) *	1978-02-08	1979-08-28	Eli Lilly And Company	6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4180582A (en) *	1978-02-08	1979-12-25	Eli Lilly And Company	6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4202979A (en) *	1979-01-11	1980-05-13	Eli Lilly And Company	6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) *	1979-10-01	1981-01-20	Eli Lilly And Company	6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) *	1979-12-06	1983-05-10	Farmitalia Carlo Erba S.P.A.	Ercoline derivatives and therapeutic compositions having CNS affecting activity
DE3216870A1 (en) *	1982-05-03	1983-11-03	Schering AG, 1000 Berlin und 4709 Bergkamen	PHARMACEUTICAL PREPARATIONS WITH A CYTOSTATIC EFFECT
FR2526797A1 (en) *	1982-05-12	1983-11-18	Roussel Uclaf	NOVEL 9-OXALYSERGIC ACID DERIVATIVES, THEIR SALTS, PREPARATION METHOD, MEDICAMENT APPLICATION AND COMPOSITIONS COMPRISING THE SAME
CH649998A5 (en) *	1982-08-09	1985-06-28	Sandoz Ag	ERGOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND HEALING AGENTS, CONTAINING THESE ERGOL DERIVATIVES AS AN ACTIVE SUBSTANCE.
GB8427536D0 (en) *	1984-10-31	1984-12-05	Lilly Industries Ltd	Ergoline derivatives
US4675322A (en) *	1984-12-10	1987-06-23	Eli Lilly And Company	1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) *	1985-06-24	1989-01-31	Eli Lilly And Company	2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (en) *	1985-11-13	1988-09-02	Roussel Uclaf	USE OF ERGOLIN DERIVATIVES FOR OBTAINING A GERIATRIC MEDICINE
HU196394B (en) *	1986-06-27	1988-11-28	Richter Gedeon Vegyeszet	Process for preparing 2-halogenated ergoline derivatives
ATE424414T1 (en) *	2001-06-08	2009-03-15	Sod Conseils Rech Applic	CHIMERS SOMATOSTATIN-DOPAMINE ANALOGUE
DE60324776D1 (en) *	2002-03-15	2009-01-02	Antibioticos Spa	PROCESS FOR SYNTHESIS OF PERGOLID
TWI523863B (en)	2012-11-01	2016-03-01	艾普森藥品公司	Somatostatin-dopamine chimeric analogs
US9777039B2 (en)	2012-11-01	2017-10-03	Ipsen Pharma S.A.S.	Somatostatin analogs and dimers thereof
EP3197429B1 (en)	2014-09-25	2024-05-22	Boehringer Ingelheim Vetmedica GmbH	Combination treatment of sglt2 inhibitors and dopamine agonists for preventing metabolic disorders in equine animals
US20190374534A1 (en)	2018-06-08	2019-12-12	Boehringer Ingelheim Vetmedica Gmbh	Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH507248A (en) *	1967-03-16	1971-05-15	Spofa Vereinigte Pharma Werke	Process for the preparation of D-6-methylergolin (I) ylacetic acid
DE1935556A1 (en) *	1969-07-12	1971-01-21	Hoechst Ag	Process for the production of lysergol
JPS5012398A (en) *	1973-06-08	1975-02-07

1974
- 1974-06-06 US US477136A patent/US3901894A/en not_active Expired - Lifetime
1975
- 1975-05-16 JP JP50059191A patent/JPS582946B2/en not_active Expired
- 1975-06-03 HU HU75EI623A patent/HU173590B/en unknown
- 1975-06-03 CS CS753882A patent/CS199591B2/en unknown
- 1975-06-03 PH PH17225A patent/PH10992A/en unknown
- 1975-06-03 SE SE7506327A patent/SE420095B/en not_active IP Right Cessation
- 1975-06-03 NL NLAANVRAGE7506584,A patent/NL180911C/en not_active IP Right Cessation
- 1975-06-03 IE IE1221/75A patent/IE41474B1/en unknown
- 1975-06-03 CA CA228,332A patent/CA1071623A/en not_active Expired
- 1975-06-03 GB GB23869/75A patent/GB1505296A/en not_active Expired
- 1975-06-03 DE DE19752524575 patent/DE2524575A1/en not_active Ceased
- 1975-06-04 IL IL47424A patent/IL47424A/en unknown
- 1975-06-04 DK DK249975A patent/DK144160C/en not_active IP Right Cessation
- 1975-06-04 PL PL1975180897A patent/PL95738B1/en unknown
- 1975-06-04 AU AU81827/75A patent/AU507574B2/en not_active Expired
- 1975-06-04 BG BG030188A patent/BG24812A3/en unknown
- 1975-06-05 BE BE1006709A patent/BE829887A/en not_active IP Right Cessation
- 1975-06-05 ZA ZA3638A patent/ZA753638B/en unknown
- 1975-06-05 AT AT427975A patent/AT344333B/en not_active IP Right Cessation
- 1975-06-05 RO RO7582445A patent/RO77543A/en unknown
- 1975-06-05 FR FR7517652A patent/FR2273542A1/en active Granted
- 1975-06-05 SU SU752140862A patent/SU613724A3/en active
- 1975-06-05 YU YU01455/75A patent/YU145575A/en unknown
- 1975-06-06 ES ES438313A patent/ES438313A1/en not_active Expired
- 1975-06-06 AR AR259118A patent/AR210736A1/en active
- 1975-06-06 CH CH731075A patent/CH617196A5/de not_active IP Right Cessation
1976
- 1976-06-05 DD DD186472A patent/DD120438A5/xx unknown

Also Published As

Publication number	Publication date
FR2273542A1 (en)	1976-01-02
ZA753638B (en)	1977-01-26
ES438313A1 (en)	1977-05-16
CH617196A5 (en)	1980-05-14
DE2524575A1 (en)	1975-12-18
PL95738B1 (en)	1977-11-30
DD120438A5 (en)	1976-06-12
US3901894A (en)	1975-08-26
AT344333B (en)	1978-07-10
SE420095B (en)	1981-09-14
CS199591B2 (en)	1980-07-31
HU173590B (en)	1979-06-28
GB1505296A (en)	1978-03-30
IE41474B1 (en)	1980-01-16
SU613724A3 (en)	1978-06-30
AU507574B2 (en)	1980-02-21
NL180911C (en)	1987-05-18
SE7506327L (en)	1975-12-08
RO77543A (en)	1982-02-26
ATA427975A (en)	1977-11-15
PH10992A (en)	1977-10-20
IL47424A (en)	1979-11-30
BG24812A3 (en)	1978-05-12
NL7506584A (en)	1975-12-09
JPS50160300A (en)	1975-12-25
FR2273542B1 (en)	1978-10-06
IE41474L (en)	1975-12-06
CA1071623A (en)	1980-02-12
JPS582946B2 (en)	1983-01-19
AR210736A1 (en)	1977-09-15
IL47424A0 (en)	1975-08-31
DK249975A (en)	1975-12-07
DK144160C (en)	1982-06-07
NL180911B (en)	1986-12-16
YU145575A (en)	1982-02-28
BE829887A (en)	1975-12-05
DK144160B (en)	1981-12-28

Publication	Publication Date	Title
AU497500B2 (en)	1978-12-14	Adriamycins
AU507574B2 (en)	1980-02-21	8-thiomethyl ergolines
AU497203B2 (en)	1978-12-07	Neohelometer
AU500773B2 (en)	1979-05-31	Carbonylaldiminomethanephosphonates
AU505194B2 (en)	1979-11-15	8, 8-disubstituted-6-methyl ergolines
AU505415B2 (en)	1979-11-22	Sofabed
AU498226B2 (en)	1979-02-22	Ergoline compounds
AU496973B2 (en)	1978-11-16	5-nitro-imidazoles
AU499459B2 (en)	1979-04-26	Antioboitics
AU503202B2 (en)	1979-08-30	3-methylenecepham sulfonides
AU499812B2 (en)	1979-05-03	Halo-pregnanes
AU507312B2 (en)	1980-02-14	1-aryloxy-4-amino-2-butanols
AU506970B2 (en)	1980-01-31	4d-phenyl-decahydroisoquinolines
AU504180B2 (en)	1979-10-04	Hexanhydroindolinols
AU497650B2 (en)	1978-12-21	2-aryl-4-cyanomethyl-5-methylimidazoles
AU504398B2 (en)	1979-10-11	Steroidal-3-thiones
AU484806B2 (en)	1975-03-06	Benzopyran-3-carbonitriles
AU468625B2 (en)	1976-01-15	Wire-connector
AU489561B2 (en)		Amidinoureas
AU490236B2 (en)	1976-09-23	Daunomycins
AU491120B2 (en)	1977-04-21	7d-hydroxy-oestradiol
AU491257B2 (en)	1976-08-26	11b-fluoro-androstenes
AU491788B2 (en)	1977-05-05	5-heptyl-2-hydroxybenzaldoximes
AU492269B2 (en)	1975-03-06	14-desoxy-14-tosyloxyacetoxy-mutilin
AU493093B2 (en)	1976-11-25	Pyridobenzodiazepinones