NL180911C - METHOD FOR PREPARING PHARMACEUTICAL PREPARATIONS AND METHOD FOR PREPARING ERGOLINE DERIVATIVES - Google Patents

METHOD FOR PREPARING PHARMACEUTICAL PREPARATIONS AND METHOD FOR PREPARING ERGOLINE DERIVATIVES

Info

Publication number: NL180911C
Authority: NL; Netherlands
Prior art keywords: preparing; pharmaceutical preparations; ergoline derivatives; preparing pharmaceutical; derivatives
Prior art date: 1974-06-06

Application number

NLAANVRAGE7506584,A

Other languages

Dutch (nl)

Other versions

NL180911B (en

NL7506584A (en

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-06-06

Filing date

1975-06-03

Publication date

1987-05-18

1975-06-03 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1975-12-09 Publication of NL7506584A publication Critical patent/NL7506584A/en

1986-12-16 Publication of NL180911B publication Critical patent/NL180911B/en

1987-05-18 Application granted granted Critical

1987-05-18 Publication of NL180911C publication Critical patent/NL180911C/en

Links

238000000034 method Methods 0.000 title 2
AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical class O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NLAANVRAGE7506584,A 1974-06-06 1975-06-03 METHOD FOR PREPARING PHARMACEUTICAL PREPARATIONS AND METHOD FOR PREPARING ERGOLINE DERIVATIVES NL180911C (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US477136A US3901894A (en)	1974-06-06	1974-06-06	8-thiomethylergolines

Publications (3)

Publication Number	Publication Date
NL7506584A NL7506584A (en)	1975-12-09
NL180911B NL180911B (en)	1986-12-16
NL180911C true NL180911C (en)	1987-05-18

Family

ID=23894677

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NLAANVRAGE7506584,A NL180911C (en)	1974-06-06	1975-06-03	METHOD FOR PREPARING PHARMACEUTICAL PREPARATIONS AND METHOD FOR PREPARING ERGOLINE DERIVATIVES

Country Status (27)

Country	Link
US (1)	US3901894A (en)
JP (1)	JPS582946B2 (en)
AR (1)	AR210736A1 (en)
AT (1)	AT344333B (en)
AU (1)	AU507574B2 (en)
BE (1)	BE829887A (en)
BG (1)	BG24812A3 (en)
CA (1)	CA1071623A (en)
CH (1)	CH617196A5 (en)
CS (1)	CS199591B2 (en)
DD (1)	DD120438A5 (en)
DE (1)	DE2524575A1 (en)
DK (1)	DK144160C (en)
ES (1)	ES438313A1 (en)
FR (1)	FR2273542A1 (en)
GB (1)	GB1505296A (en)
HU (1)	HU173590B (en)
IE (1)	IE41474B1 (en)
IL (1)	IL47424A (en)
NL (1)	NL180911C (en)
PH (1)	PH10992A (en)
PL (1)	PL95738B1 (en)
RO (1)	RO77543A (en)
SE (1)	SE420095B (en)
SU (1)	SU613724A3 (en)
YU (1)	YU145575A (en)
ZA (1)	ZA753638B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4147789A (en) *	1974-03-14	1979-04-03	Sandoz Ltd.	6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) *	1974-12-13	1976-05-25	Eli Lilly And Company	8-Oxymethylergolines and process therefor
JPS5283894A (en) *	1976-01-01	1977-07-13	Lilly Co Eli	88thiomethyl ergoline
GB1549829A (en) *	1976-05-26	1979-08-08	Farmaceutici Italia	10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (en) *	1977-07-05	1988-03-31	Simes	ERGOLINE-2-THIOETHERS AND THEIR SULPHOXIDES DERIVATIVES
US4180582A (en) *	1978-02-08	1979-12-25	Eli Lilly And Company	6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4166182A (en) *	1978-02-08	1979-08-28	Eli Lilly And Company	6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4202979A (en) *	1979-01-11	1980-05-13	Eli Lilly And Company	6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) *	1979-10-01	1981-01-20	Eli Lilly And Company	6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) *	1979-12-06	1983-05-10	Farmitalia Carlo Erba S.P.A.	Ercoline derivatives and therapeutic compositions having CNS affecting activity
DE3216870A1 (en) *	1982-05-03	1983-11-03	Schering AG, 1000 Berlin und 4709 Bergkamen	PHARMACEUTICAL PREPARATIONS WITH A CYTOSTATIC EFFECT
FR2526797A1 (en) *	1982-05-12	1983-11-18	Roussel Uclaf	NOVEL 9-OXALYSERGIC ACID DERIVATIVES, THEIR SALTS, PREPARATION METHOD, MEDICAMENT APPLICATION AND COMPOSITIONS COMPRISING THE SAME
CH649998A5 (en) *	1982-08-09	1985-06-28	Sandoz Ag	ERGOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND HEALING AGENTS, CONTAINING THESE ERGOL DERIVATIVES AS AN ACTIVE SUBSTANCE.
GB8427536D0 (en) *	1984-10-31	1984-12-05	Lilly Industries Ltd	Ergoline derivatives
US4675322A (en) *	1984-12-10	1987-06-23	Eli Lilly And Company	1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) *	1985-06-24	1989-01-31	Eli Lilly And Company	2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (en) *	1985-11-13	1988-09-02	Roussel Uclaf	USE OF ERGOLIN DERIVATIVES FOR OBTAINING A GERIATRIC MEDICINE
HU196394B (en) *	1986-06-27	1988-11-28	Richter Gedeon Vegyeszet	Process for preparing 2-halogenated ergoline derivatives
DK2062914T3 (en) *	2001-06-08	2014-07-14	Ipsen Pharma	Somatostatin-dopamine chimeric analogs
DE60324776D1 (en) *	2002-03-15	2009-01-02	Antibioticos Spa	PROCESS FOR SYNTHESIS OF PERGOLID
TWI523863B (en)	2012-11-01	2016-03-01	艾普森藥品公司	Somatostatin-dopamine chimeric analogs
RU2015120570A (en)	2012-11-01	2016-12-20	Ипсен Фарма С.А.С.	SOMATOSTATIN ANALOGUES AND THEIR DIMERS
KR102539788B1 (en)	2014-09-25	2023-06-07	베링거잉겔하임베트메디카게엠베하	Combination treatment of sglt2 inhibitors and dopamine agonists for preventing metabolic disorders in equine animals
WO2019234069A1 (en)	2018-06-08	2019-12-12	Boehringer Ingelheim Vetmedica Gmbh	Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH507248A (en) *	1967-03-16	1971-05-15	Spofa Vereinigte Pharma Werke	Process for the preparation of D-6-methylergolin (I) ylacetic acid
DE1935556A1 (en) *	1969-07-12	1971-01-21	Hoechst Ag	Process for the production of lysergol
JPS5012398A (en) *	1973-06-08	1975-02-07

1974
- 1974-06-06 US US477136A patent/US3901894A/en not_active Expired - Lifetime
1975
- 1975-05-16 JP JP50059191A patent/JPS582946B2/en not_active Expired
- 1975-06-03 NL NLAANVRAGE7506584,A patent/NL180911C/en not_active IP Right Cessation
- 1975-06-03 CA CA228,332A patent/CA1071623A/en not_active Expired
- 1975-06-03 GB GB23869/75A patent/GB1505296A/en not_active Expired
- 1975-06-03 IE IE1221/75A patent/IE41474B1/en unknown
- 1975-06-03 PH PH17225A patent/PH10992A/en unknown
- 1975-06-03 CS CS753882A patent/CS199591B2/en unknown
- 1975-06-03 HU HU75EI623A patent/HU173590B/en unknown
- 1975-06-03 SE SE7506327A patent/SE420095B/en not_active IP Right Cessation
- 1975-06-03 DE DE19752524575 patent/DE2524575A1/en not_active Ceased
- 1975-06-04 BG BG030188A patent/BG24812A3/en unknown
- 1975-06-04 IL IL47424A patent/IL47424A/en unknown
- 1975-06-04 PL PL1975180897A patent/PL95738B1/en unknown
- 1975-06-04 DK DK249975A patent/DK144160C/en not_active IP Right Cessation
- 1975-06-04 AU AU81827/75A patent/AU507574B2/en not_active Expired
- 1975-06-05 BE BE1006709A patent/BE829887A/en not_active IP Right Cessation
- 1975-06-05 RO RO7582445A patent/RO77543A/en unknown
- 1975-06-05 ZA ZA3638A patent/ZA753638B/en unknown
- 1975-06-05 AT AT427975A patent/AT344333B/en not_active IP Right Cessation
- 1975-06-05 SU SU752140862A patent/SU613724A3/en active
- 1975-06-05 FR FR7517652A patent/FR2273542A1/en active Granted
- 1975-06-05 YU YU01455/75A patent/YU145575A/en unknown
- 1975-06-06 AR AR259118A patent/AR210736A1/en active
- 1975-06-06 ES ES438313A patent/ES438313A1/en not_active Expired
- 1975-06-06 CH CH731075A patent/CH617196A5/de not_active IP Right Cessation
1976
- 1976-06-05 DD DD186472A patent/DD120438A5/xx unknown

Also Published As

Publication number	Publication date
JPS50160300A (en)	1975-12-25
AR210736A1 (en)	1977-09-15
IE41474L (en)	1975-12-06
HU173590B (en)	1979-06-28
NL180911B (en)	1986-12-16
SE7506327L (en)	1975-12-08
US3901894A (en)	1975-08-26
GB1505296A (en)	1978-03-30
NL7506584A (en)	1975-12-09
PL95738B1 (en)	1977-11-30
CH617196A5 (en)	1980-05-14
DK249975A (en)	1975-12-07
PH10992A (en)	1977-10-20
CA1071623A (en)	1980-02-12
FR2273542A1 (en)	1976-01-02
YU145575A (en)	1982-02-28
SE420095B (en)	1981-09-14
IE41474B1 (en)	1980-01-16
RO77543A (en)	1982-02-26
FR2273542B1 (en)	1978-10-06
DK144160B (en)	1981-12-28
ATA427975A (en)	1977-11-15
AU8182775A (en)	1976-12-09
BE829887A (en)	1975-12-05
DK144160C (en)	1982-06-07
IL47424A (en)	1979-11-30
CS199591B2 (en)	1980-07-31
IL47424A0 (en)	1975-08-31
DD120438A5 (en)	1976-06-12
AU507574B2 (en)	1980-02-21
DE2524575A1 (en)	1975-12-18
JPS582946B2 (en)	1983-01-19
ES438313A1 (en)	1977-05-16
AT344333B (en)	1978-07-10
ZA753638B (en)	1977-01-26
BG24812A3 (en)	1978-05-12
SU613724A3 (en)	1978-06-30

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Legal Events

Date	Code	Title	Description
1993-02-16	V1	Lapsed because of non-payment of the annual fee