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AU2110000A - Use of substituted isoxazol carboxylic acids and derivatives and novel substances - Google Patents

Use of substituted isoxazol carboxylic acids and derivatives and novel substances

Info

Publication number
AU2110000A
AU2110000A AU21100/00A AU2110000A AU2110000A AU 2110000 A AU2110000 A AU 2110000A AU 21100/00 A AU21100/00 A AU 21100/00A AU 2110000 A AU2110000 A AU 2110000A AU 2110000 A AU2110000 A AU 2110000A
Authority
AU
Australia
Prior art keywords
derivatives
carboxylic acids
novel substances
substituted isoxazol
isoxazol carboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU21100/00A
Inventor
Martin Bechem
Gabriele Braunlich
Christoph Dr. Gerdes
Berthold Hinzen
Thomas Kramer
Emanuel Lohrmann
Klemens Lustig
Lorenz Mayr
Ulrich Dr Nielsch
Josef Pernerstorfer
Michael Sperzel
Jurgen Stoltefuss
Thomas Studemann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU2110000A publication Critical patent/AU2110000A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AU21100/00A 1999-02-04 2000-01-24 Use of substituted isoxazol carboxylic acids and derivatives and novel substances Abandoned AU2110000A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19904389 1999-02-04
DE19904389A DE19904389A1 (en) 1999-02-04 1999-02-04 Use of substituted isoxazolecarboxylic acids and derivatives and new substances
PCT/EP2000/000517 WO2000045799A2 (en) 1999-02-04 2000-01-24 Use of substituted isoxazol carboxylic acids and derivatives and novel substances

Publications (1)

Publication Number Publication Date
AU2110000A true AU2110000A (en) 2000-08-25

Family

ID=7896332

Family Applications (1)

Application Number Title Priority Date Filing Date
AU21100/00A Abandoned AU2110000A (en) 1999-02-04 2000-01-24 Use of substituted isoxazol carboxylic acids and derivatives and novel substances

Country Status (5)

Country Link
AR (1) AR022469A1 (en)
AU (1) AU2110000A (en)
DE (1) DE19904389A1 (en)
GT (1) GT200000011A (en)
WO (1) WO2000045799A2 (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037068A1 (en) 1997-02-21 1998-08-27 Bristol-Myers Squibb Company Benzoic acid derivatives and related compounds as antiarrhythmic agents
MY151199A (en) 2001-11-02 2014-04-30 Rigel Pharmaceuticals Inc Substituted diphenyl heterocycles useful for treating hcv infection
JP2006501312A (en) 2002-08-23 2006-01-12 ライジェル ファーマシューティカルズ, インコーポレイテッド Pyridyl-substituted heterocycles useful for treating or preventing HCV infection
US7115642B2 (en) 2003-05-02 2006-10-03 Rigel Pharmaceuticals, Inc. Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating HCV infection
US7326790B2 (en) 2003-05-02 2008-02-05 Rigel Pharmaceuticals, Inc. Diphenylisoxazole compounds and hydro isomers thereof
US7220745B2 (en) 2003-05-15 2007-05-22 Rigel Pharmaceuticals Heterocyclic compounds useful to treat HCV
US8580842B2 (en) 2003-09-30 2013-11-12 Abbott Gmbh & Co. Kg Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
US7410979B2 (en) 2003-11-19 2008-08-12 Rigel Pharmaceuticals, Inc. Synergistically effective combinations of dihaloacetamide compounds and interferon or ribavirin against HCV infections
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
WO2006044456A1 (en) 2004-10-13 2006-04-27 Ptc Therapeutics, Inc. Compounds for nonsense suppression, and methods for their use
CN101203498A (en) 2005-05-02 2008-06-18 里格尔药品股份有限公司 Heterocyclic antiviral compounds including metabolizable moieties and uses thereof
EP1893591A1 (en) * 2005-06-08 2008-03-05 Novartis AG POLYCYCLIC OXADIAZOLES OR I SOXAZOLES AND THEIR USE AS SlP RECEPTOR LIGANDS
GB0601744D0 (en) * 2006-01-27 2006-03-08 Novartis Ag Organic compounds
AR062683A1 (en) 2006-09-07 2008-11-26 Actelion Pharmaceuticals Ltd COMPOUNDS DERIVED FROM PIRIDIN-4-ILO, PHARMACEUTICAL COMPOSITION CONTAINING THEM, AND USE OF THE SAME IN THE PREPARATION OF MEDICINES
DK2069335T3 (en) * 2006-09-08 2013-02-18 Actelion Pharmaceuticals Ltd PYRIDIN-3-YLD DERIVATIVES AS IMMUNO MODULATORS
US20080167286A1 (en) 2006-12-12 2008-07-10 Abbott Laboratories Pharmaceutical compositions and their methods of use
US8486979B2 (en) 2006-12-12 2013-07-16 Abbvie Inc. 1,2,4 oxadiazole compounds and methods of use thereof
UY30846A1 (en) 2006-12-30 2008-07-31 Abbott Gmbh & Amp OXINDOL DERIVATIVES REPLACED, MEDICINES THAT UNDERSTAND AND USE THEMSELVES
EP2125797B1 (en) 2007-03-16 2014-01-15 Actelion Pharmaceuticals Ltd. Amino- pyridine derivatives as s1p1 /edg1 receptor agonists
WO2009029632A1 (en) 2007-08-27 2009-03-05 Helicon Therapeutics, Inc. Therapeutic isoxazole compounds
MX2010006202A (en) 2007-12-07 2011-03-04 Abbott Gmbh & Co Kg Amidomethyl-substituted oxindole derivatives and the use thereof for the treatment of vasopressin-dependent illnesses.
WO2010009775A1 (en) 2007-12-07 2010-01-28 Abbott Gmbh & Co. Kg Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases
CA2707669C (en) 2007-12-07 2016-07-05 Wilfried Braje 5-halogen-substituted oxindole derivatives and use thereof for treating vasopressine-dependent diseases
WO2009071690A2 (en) 2007-12-07 2009-06-11 Abbott Gmbh & Co. Kg 5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressine-dependent diseases
WO2010138600A2 (en) 2009-05-29 2010-12-02 Abbott Laboratories Pharmaceutical compositions for the treatment of pain
WO2011005660A1 (en) 2009-07-08 2011-01-13 Valocor Therapeutics, Inc. Tofa analogs useful in treating dermatological disorders or conditions
SG178042A1 (en) 2009-07-16 2012-03-29 Actelion Pharmaceuticals Ltd Pyridin-4-yl derivatives
SI2665720T1 (en) 2011-01-19 2015-08-31 Actelion Pharmaceuticals Ltd. 2-methoxy-pyridin-4-yl derivatives
CN102329277B (en) * 2011-10-24 2013-08-07 海南霞迪药业有限公司 Method for preparing Parecoxib
US10385043B2 (en) 2015-05-20 2019-08-20 Idorsia Pharmaceuticals Ltd Crystalline form of the compound (S)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol
CN116535399B (en) * 2022-01-25 2024-02-27 中国药科大学 3-hydroxy-5- (isoxazol-5-yl) pyridine formyl glycine compound, preparation method, pharmaceutical composition and application
WO2024029638A1 (en) * 2022-08-01 2024-02-08 한국과학기술연구원 Novel heterocyclyl-phenyl-methylamine derivative, preparation method therefor, and use thereof for prevention, alleviation, or treatment of multiple sclerosis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB149877A (en) * 1919-11-22 1920-08-26 Arthur William Wells Improvements in and in connection with safety razors
ES488768A0 (en) * 1979-02-22 1981-02-16 Monsanto Co A PROCEDURE FOR PREPARING ACID 2- (3-ARIL-5-ISOXAZOLIL) -BENZOIC
US5330994A (en) * 1992-03-24 1994-07-19 Warner-Lambert Company Tetrahydropyridine isoxazoline derivatives
DE4314966A1 (en) * 1993-05-06 1994-11-10 Fahlberg List Pharma Gmbh 2-Hydroxyphenyl-substituted isoxazoles, the use thereof as pharmaceutical agents and pharmaceutical compositions containing them
WO1997019039A1 (en) * 1995-11-17 1997-05-29 Novartis Ag Solid phase synthesis of heterocyclic compounds and combinatorial compound library
DE19640370C1 (en) * 1996-09-30 1998-02-12 Dornier Gmbh Lindauer Assemblies to hold and guide loom shaft rods
EP0994101A4 (en) * 1997-06-18 2002-05-02 Fujisawa Pharmaceutical Co New production process

Also Published As

Publication number Publication date
WO2000045799A3 (en) 2002-01-24
WO2000045799A2 (en) 2000-08-10
GT200000011A (en) 2001-07-27
AR022469A1 (en) 2002-09-04
DE19904389A1 (en) 2000-08-10

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase