[go: up one dir, main page]

AR022469A1 - USE OF SUBSTITUTED AND DERIVATIVE ISOXAZOLCARBOXILIC ACIDS AND NEW SUBSTANCES - Google Patents

USE OF SUBSTITUTED AND DERIVATIVE ISOXAZOLCARBOXILIC ACIDS AND NEW SUBSTANCES

Info

Publication number
AR022469A1
AR022469A1 ARP000100427A ARP000100427A AR022469A1 AR 022469 A1 AR022469 A1 AR 022469A1 AR P000100427 A ARP000100427 A AR P000100427A AR P000100427 A ARP000100427 A AR P000100427A AR 022469 A1 AR022469 A1 AR 022469A1
Authority
AR
Argentina
Prior art keywords
acids
substituted
isoxazolcarboxilic
derivative
new substances
Prior art date
Application number
ARP000100427A
Other languages
Spanish (es)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of AR022469A1 publication Critical patent/AR022469A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

La presente invencion se refiere al uso de ácidos isoxazolcarboxílicos sustituidos y derivados de formula general (1) para el tratamiento y profilaxis deenfermedades de anemias, así como de nuevas sustancias de formula general (2) y a nuevos procedimientos para su obtencion.The present invention relates to the use of substituted isoxazolcarboxylic acids and derivatives of the general formula (1) for the treatment and prophylaxis of anemia diseases, as well as new substances of the general formula (2) and to new methods for obtaining them.

ARP000100427A 1999-02-04 2000-02-01 USE OF SUBSTITUTED AND DERIVATIVE ISOXAZOLCARBOXILIC ACIDS AND NEW SUBSTANCES AR022469A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19904389A DE19904389A1 (en) 1999-02-04 1999-02-04 Use of substituted isoxazolecarboxylic acids and derivatives and new substances

Publications (1)

Publication Number Publication Date
AR022469A1 true AR022469A1 (en) 2002-09-04

Family

ID=7896332

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000100427A AR022469A1 (en) 1999-02-04 2000-02-01 USE OF SUBSTITUTED AND DERIVATIVE ISOXAZOLCARBOXILIC ACIDS AND NEW SUBSTANCES

Country Status (5)

Country Link
AR (1) AR022469A1 (en)
AU (1) AU2110000A (en)
DE (1) DE19904389A1 (en)
GT (1) GT200000011A (en)
WO (1) WO2000045799A2 (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6320998A (en) 1997-02-21 1998-09-09 Bristol-Myers Squibb Company Benzoic acid derivatives and related compounds as antiarrhythmic agents
MY151199A (en) 2001-11-02 2014-04-30 Rigel Pharmaceuticals Inc Substituted diphenyl heterocycles useful for treating hcv infection
HRP20050168A2 (en) 2002-08-23 2005-10-31 Rigel Pharmaceuticals Pyridyl substituted heterocycles useful for treating or preventing hcv infection
WO2004099164A1 (en) 2003-05-02 2004-11-18 Rigel Pharmaceuticals, Inc. Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating hcv infection
US7326790B2 (en) 2003-05-02 2008-02-05 Rigel Pharmaceuticals, Inc. Diphenylisoxazole compounds and hydro isomers thereof
US7220745B2 (en) 2003-05-15 2007-05-22 Rigel Pharmaceuticals Heterocyclic compounds useful to treat HCV
US8580842B2 (en) 2003-09-30 2013-11-12 Abbott Gmbh & Co. Kg Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
WO2005049065A2 (en) 2003-11-19 2005-06-02 Rigel Pharmaceuticals, Inc. Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
JP2008515992A (en) * 2004-10-13 2008-05-15 ピーティーシー セラピューティクス，インコーポレーテッド Use of prescribed compounds for the manufacture of medicaments for the prevention / treatment of diseases caused by somatic mutations
JP2008540425A (en) 2005-05-02 2008-11-20 ライジェル ファーマシューティカルズ， インコーポレイテッド Heterocyclic antiviral compounds containing metabolizable moieties and uses thereof
US20080306124A1 (en) * 2005-06-08 2008-12-11 Rainer Albert Polycyclic Oxadiazoles or I Soxazoles and Their Use as Sip Receptor Ligands
GB0601744D0 (en) * 2006-01-27 2006-03-08 Novartis Ag Organic compounds
CN101511827B (en) 2006-09-07 2012-02-01 埃科特莱茵药品有限公司 Pyridin-4-yl derivatives as immunomodulating agents
CA2661315C (en) * 2006-09-08 2015-11-24 Actelion Pharmaceuticals Ltd Pyridin-3-yl derivatives as immunomodulating agents
US20080167286A1 (en) 2006-12-12 2008-07-10 Abbott Laboratories Pharmaceutical compositions and their methods of use
US8486979B2 (en) 2006-12-12 2013-07-16 Abbvie Inc. 1,2,4 oxadiazole compounds and methods of use thereof
UY30846A1 (en) 2006-12-30 2008-07-31 Abbott Gmbh & Amp OXINDOL DERIVATIVES REPLACED, MEDICINES THAT UNDERSTAND AND USE THEMSELVES
SI2125797T1 (en) 2007-03-16 2014-03-31 Actelion Pharmaceuticals Ltd. Amino- pyridine derivatives as s1p1 /edg1 receptor agonists
AU2008293542B9 (en) 2007-08-27 2014-08-07 Dart Neuroscience (Cayman) Ltd. Therapeutic isoxazole compounds
ES2455197T3 (en) 2007-12-07 2014-04-14 Abbvie Deutschland Gmbh & Co Kg 5,6-disubstituted oxindole derivatives and their use for the preparation of a medicine for the treatment of vasopressin-dependent diseases
BRPI0820668A2 (en) 2007-12-07 2017-08-22 Abbott Gmbh & Co Kg 5-HALOGEN SUBSTITUTED OXINDOL DERIVATIVES AND THEIR USE TO TREAT VASOPRESSIN DEPENDENT DISEASES
WO2010009775A1 (en) 2007-12-07 2010-01-28 Abbott Gmbh & Co. Kg Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases
CA2707667C (en) 2007-12-07 2016-02-23 Abbott Gmbh & Co. Kg Amidomethyl-substituted oxindole derivatives and the use thereof for the treatment of vasopressin-dependent illnesses
US9040568B2 (en) 2009-05-29 2015-05-26 Abbvie Inc. Pharmaceutical compositions for the treatment of pain
CA2766643C (en) 2009-07-08 2017-01-03 Dermira (Canada), Inc. Tofa analogs useful in treating dermatological disorders or conditions
EP2454255B1 (en) 2009-07-16 2013-11-06 Actelion Pharmaceuticals Ltd. Pyridin-4-yl derivatives as s1p1/edg1 agonists
ES2544086T3 (en) 2011-01-19 2015-08-27 Actelion Pharmaceuticals Ltd. 2-Methoxy-pyridin-4-yl derivatives
CN102329277B (en) * 2011-10-24 2013-08-07 海南霞迪药业有限公司 Method for preparing Parecoxib
PH12017502097B1 (en) 2015-05-20 2023-05-05 Idorsia Pharmaceuticals Ltd Crystalline form of the compound (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol
CN116535399B (en) * 2022-01-25 2024-02-27 中国药科大学 3-hydroxy-5- (isoxazol-5-yl) pyridine formyl glycine compound, preparation method, pharmaceutical composition and application
EP4567034A1 (en) * 2022-08-01 2025-06-11 Korea Institute of Science and Technology Novel heterocyclyl-phenyl-methylamine derivative, preparation method therefor, and use thereof for prevention, alleviation, or treatment of multiple sclerosis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB149877A (en) * 1919-11-22 1920-08-26 Arthur William Wells Improvements in and in connection with safety razors
DE3065860D1 (en) * 1979-02-22 1984-01-19 Monsanto Co Thermolysis of 2-(3-aryl-isoxazol-5-yl)benzoic acids, salts and halides from 3'-(aryl)-spiro(isobenzofuran-1(3h),5'(4'h)isoxazol)-3-ones
US5330994A (en) * 1992-03-24 1994-07-19 Warner-Lambert Company Tetrahydropyridine isoxazoline derivatives
DE4314966A1 (en) * 1993-05-06 1994-11-10 Fahlberg List Pharma Gmbh 2-Hydroxyphenyl-substituted isoxazoles, the use thereof as pharmaceutical agents and pharmaceutical compositions containing them
WO1997019039A1 (en) * 1995-11-17 1997-05-29 Novartis Ag Solid phase synthesis of heterocyclic compounds and combinatorial compound library
DE19640370C1 (en) * 1996-09-30 1998-02-12 Dornier Gmbh Lindauer Assemblies to hold and guide loom shaft rods
EP0994101A4 (en) * 1997-06-18 2002-05-02 Fujisawa Pharmaceutical Co New production process

Also Published As

Publication number Publication date
GT200000011A (en) 2001-07-27
AU2110000A (en) 2000-08-25
WO2000045799A2 (en) 2000-08-10
DE19904389A1 (en) 2000-08-10
WO2000045799A3 (en) 2002-01-24

Similar Documents

Publication Publication Date Title
AR022469A1 (en) USE OF SUBSTITUTED AND DERIVATIVE ISOXAZOLCARBOXILIC ACIDS AND NEW SUBSTANCES
HN1999000124A (en) SUBSTITUTED PYRAZOLE DERIVATIVES.
BRPI0409611A (en) piperazine derivatives and their use for the treatment of neurological and psychiatric disorders
CY1121202T1 (en) PYRROL PRODUCTS [2,3-b)] PYRIMIDINE AS A MOVEMENT INHIBITOR JANUS
EA200600621A1 (en) DERIVATIVES OF TETRAHYDRONAPTALINE, METHOD OF THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY MEANS
UY26495A1 (en) "THIAZOLYLAMIDE DERIVATIVES"
DE60204452D1 (en) [1,5] pyridine derivatives
BRPI0408347A (en) pyrimidine derivatives
SV1999000047A (en) NEW DIHYDROPYRIMIDINES FEF. READ 32792-SV
GT200100137A (en) PRO-DRUGS OF 4-PHENYL-PYRIDINE DERIVATIVES.
CY1109558T1 (en) Benzo derivative [D] AZEPINIS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
WO2002055496A8 (en) Aryl piperidine and piperazine derivatives as inducers of ldl-receptor expression
AR047529A1 (en) SUBSTITUTED QUINOLINE COMPOUNDS
MX9503529A (en) Glycinamide derivatives, process for their preparation and medicaments containing them.
ES2243579T3 (en) DERIVATIVES OF PIRAZOLOPIRIDENO.
ECSP045469A (en) THE USE OF REPLACED CYANOPIRROLIDINS AND COMBINATION PREPARATIONS CONTAINING THEM TO TREAT HYPERLIPIDEMIA AND ASSOCIATED DISEASES
CR9182A (en) DERIVATIVE OF QUINOLINA, ITS USE, PREPARATION AND MEDICINAL PRODUCT CONTAINING IT
PA8573501A1 (en) BENZOXAZINE DERIVATIVES AND THEIR EMPLOYMENT
BRPI0409376A (en) indene derivatives as pharmaceutical agents
UY27451A1 (en) 2,5-DIAMIDOINDOLES REPLACED AND ITS USE
BR0114380A (en) 1-Aminobutan-3-ol-substituted derivatives
BR0016638B1 (en) Substituted homopiperidylbenzimidazole analog compounds as authentic relaxants, process for preparing same, pharmaceutical composition and process for preparing it.
UY27733A1 (en) CYCLOPENTENE DERIVATIVES
DE60226313D1 (en) USE OF SESQUITERPENE COMPOSITIONS FOR THE TREATMENT OF CANCER
PA8558901A1 (en) NEW HEXACICLIC COMPOUNDS